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Select item 102627841.

Substitution of PINK1 Gly411 modulates substrate receptivity and turnover

Fabienne C Fiesel, Dominika Fričová, Caleb S Hayes, Mathew A Coban, Roman Hudec, Jenny M Bredenberg, Benjamin J Broadway, Briana N Markham, Tingxiang Yan, Paige K Boneski, Gabriella Fiorino, Jens O Watzlawik, Xu Hou, Arthur M McCarty, Laura J Lewis-Tuffin, Jun Zhong, Benjamin J Madden, Alban Ordureau, Heeseon An, Andreas Puschmann, Zbigniew K Wszolek, Owen A Ross, J Wade Harper, Thomas R Caulfield, Wolfdieter Springer

Autophagy. 2023; 19(6): 1711–1732. Published online 2022 Dec 5. doi: 10.1080/15548627.2022.2151294

PMCID:: PMC10262784

Article PDF–5.5M

Select item 101968652.

PTEN-induced kinase PINK1 supports colorectal cancer growth by regulating the labile iron pool

Brandon Chen, Nupur K. Das, Indrani Talukder, Rashi Singhal, Cristina Castillo, Anthony Andren, Joseph D. Mancias, Costas A. Lyssiotis, Yatrik M. Shah

J Biol Chem. 2023 May; 299(5): 104691. Published online 2023 Apr 8. doi: 10.1016/j.jbc.2023.104691

PMCID:: PMC10196865

Article PDF–3.2M

Select item 99483483.

PINK1 regulates apoptosis of osteosarcoma as the target gene of cisplatin

Zhenxing Si, Zilong Shen, Feiyu Luan, Jinglong Yan

J Orthop Surg Res. 2023; 18: 132. Published online 2023 Feb 23. doi: 10.1186/s13018-023-03615-w

PMCID:: PMC9948348

Article PDF–2.7M

Select item 97460614.

The emerging multifaceted role of PINK1 in cancer biology

Meng Wang, Shijia Luan, Xiang Fan, Jie Wang, Ju Huang, Xu Gao, Dong Han

Cancer Sci. 2022 Dec; 113(12): 4037–4047. Published online 2022 Oct 1. doi: 10.1111/cas.15568

PMCID:: PMC9746061

Article PDF–3.9M

Select item 91143765.

piR-823 inhibits cell apoptosis via modulating mitophagy by binding to PINK1 in colorectal cancer

Shuling Wang, Xiaoyu Jiang, Xiaoli Xie, Jie Yin, Jiuna Zhang, Ting Liu, Shujia Chen, Yijun Wang, Xue Zhou, Yongjuan Wang, Ruolin Cui, Huiqing Jiang

Cell Death Dis. 2022 May; 13(5): 465. Published online 2022 May 17. doi: 10.1038/s41419-022-04922-6

PMCID:: PMC9114376

Article PDF–7.7M

Select item 90445776.

PINK1 mediated mitophagy attenuates early apoptosis of gingival epithelial cells induced by high glucose

Chunhui Zhu, Ying Zhao, Dandan Pei, Zhongbo Liu, Jin Liu, Ye Li, Shuchen Yu, Lingyan Ma, Junyi Sun, Ang Li

BMC Oral Health. 2022; 22: 144. Published online 2022 Apr 26. doi: 10.1186/s12903-022-02167-5

PMCID:: PMC9044577

Article PDF–4.8M

Select item 88652877.

The PINK1 advantage: recycling mitochondria in times of trouble?

Zak Doric, Huihui Li, Ken Nakamura

Autophagy. 2022; 18(1): 231–232. Published online 2021 Nov 23. doi: 10.1080/15548627.2021.1998872

PMCID:: PMC8865287

Article PDF–300K

Select item 87671938.

Mapping of a N-terminal α-helix domain required for human PINK1 stabilization, Serine228 autophosphorylation and activation in cells

Poonam Kakade, Hina Ojha, Olawale G. Raimi, Andrew Shaw, Andrew D. Waddell, James R. Ault, Sophie Burel, Kathrin Brockmann, Atul Kumar, Mohd Syed Ahangar, Ewelina M. Krysztofinska, Thomas Macartney, Richard Bayliss, Julia C. Fitzgerald, Miratul M. K. Muqit

Open Biol. 2022 Jan; 12(1): 210264. Published online January 19, 2022. doi: 10.1098/rsob.210264

PMCID:: PMC8767193

Article PDF–2.1M

Select item 86414109.

PINK1 drives production of mtDNA-containing extracellular vesicles to promote invasiveness

Nicolas Rabas, Sarah Palmer, Louise Mitchell, Shehab Ismail, Andrea Gohlke, Joel S. Riley, Stephen W.G. Tait, Payam Gammage, Leandro Lemgruber Soares, Iain R. Macpherson, Jim C. Norman

J Cell Biol. 2021 Dec 6; 220(12): e202006049. Published online 2021 Oct 8. doi: 10.1083/jcb.202006049

PMCID:: PMC8641410

Article PDF–6.5M

Select item 857212710.

Targeting PINK1 Using Natural Products for the Treatment of Human Diseases

Yan-Qin Li, Fan Zhang, Li-Ping Yu, Jian-Kang Mu, Ya-Qin Yang, Jie Yu, Xing-Xin Yang

Biomed Res Int. 2021; 2021: 4045819. Published online 2021 Oct 30. doi: 10.1155/2021/4045819

PMCID:: PMC8572127

Article PDF–1004K

Select item 856099511.

Labeling and measuring stressed mitochondria using a PINK1-based ratiometric fluorescent sensor

Rie Uesugi, Shunsuke Ishii, Akira Matsuura, Eisuke Itakura

J Biol Chem. 2021 Nov; 297(5): 101279. Published online 2021 Oct 5. doi: 10.1016/j.jbc.2021.101279

PMCID:: PMC8560995

Article PDF–2.5M

Select item 822871912.

The PINK1-Mediated Crosstalk between Neural Cells and the Underlying Link to Parkinson’s Disease

Elvira Pequeno Leites, Vanessa Alexandra Morais

Cells. 2021 Jun; 10(6): 1395. Published online 2021 Jun 5. doi: 10.3390/cells10061395

PMCID:: PMC8228719

Article PDF–618K

Select item 816387813.

LncRNA H19 governs mitophagy and restores mitochondrial respiration in the heart through Pink1/Parkin signaling during obesity

Shao-Hua Wang, Xiao-Lin Zhu, Fei Wang, Si-Xu Chen, Zhi-Teng Chen, Qiong Qiu, Wen-Hao Liu, Mao-Xiong Wu, Bing-Qing Deng, Yong Xie, Jing-Ting Mai, Ying Yang, Jing-Feng Wang, Hai-Feng Zhang, Yang-Xin Chen

Cell Death Dis. 2021 Jun; 12(6): 557. Published online 2021 May 28. doi: 10.1038/s41419-021-03821-6

PMCID:: PMC8163878

Article PDF–8.6M

Select item 810112414.

PINK1 contained in huMSC-derived exosomes prevents cardiomyocyte mitochondrial calcium overload in sepsis via recovery of mitochondrial Ca²⁺ efflux

Qin Zhou, Min Xie, Jing Zhu, Qin Yi, Bin Tan, Yasha Li, Liang Ye, Xinyuan Zhang, Ying Zhang, Jie Tian, Hao Xu

Stem Cell Res Ther. 2021; 12: 269. Published online 2021 May 6. doi: 10.1186/s13287-021-02325-6

PMCID:: PMC8101124

Article PDF–3.4M

Select item 751188815.

Dependence of PINK1 accumulation on mitochondrial redox system

Feng Gao, Yan Zhang, Xiaoou Hou, Zhouteng Tao, Haigang Ren, Guanghui Wang

Aging Cell. 2020 Sep; 19(9): e13211. Published online 2020 Aug 11. doi: 10.1111/acel.13211

PMCID:: PMC7511888

Article PDF–2.7M

Select item 728031116.

Human telomerase reverse transcriptase positively regulates mitophagy by inhibiting the processing and cytoplasmic release of mitochondrial PINK1

Woo Hyun Shin, Kwang Chul Chung

Cell Death Dis. 2020 Jun; 11(6): 425. Published online 2020 Jun 8. doi: 10.1038/s41419-020-2641-7

PMCID:: PMC7280311

Article PDF–3.0M

Select item 723613317.

Comprehensive assessment of PINK1 variants in Parkinson’s disease

Lynne Krohn, Francis P. Grenn, Mary B. Makarious, Jonggeol Jeffrey Kim, Sara Bandres-Ciga, Dorien A. Roosen, Ziv Gan-Or, Mike A. Nalls, Andrew B. Singleton, Cornelis Blauwendraat

Neurobiol Aging. Author manuscript; available in PMC 2021 Jul 1.

Published in final edited form as: Neurobiol Aging. 2020 Jul; 91: 168.e1–168.e5. Published online 2020 Mar 10. doi: 10.1016/j.neurobiolaging.2020.03.003

PMCID:: PMC7236133

Article PDF–461K

Select item 694439618.

Mitochondrial Dysfunction as a Pathogenic Mediator of Chronic Obstructive Pulmonary Disease and Idiopathic Pulmonary Fibrosis

Stefan W. Ryter, Ivan O. Rosas, Caroline A. Owen, Fernando J. Martinez, Mary E. Choi, Chun Geun Lee, Jack A. Elias, Augustine M. K. Choi

Ann Am Thorac Soc. 2018 Dec; 15(Suppl 4): S266–S272. doi: 10.1513/AnnalsATS.201808-585MG

PMCID:: PMC6944396

Article PDF–911K

Select item 688147019.

Ubiquitin is double-phosphorylated by PINK1 for enhanced pH-sensitivity of conformational switch

Shang-Xiang Ye, Zhou Gong, Ju Yang, Yu-Xin An, Zhu Liu, Qun Zhao, Ewen Lescop, Xu Dong, Chun Tang

Protein Cell. 2019 Dec; 10(12): 908–913. Published online 2019 Jul 5. doi: 10.1007/s13238-019-0644-x

PMCID:: PMC6881470

Article PDF–1.3M

Select item 603946920.

Structural insights into ubiquitin phosphorylation by PINK1

Kei Okatsu, Yusuke Sato, Koji Yamano, Noriyuki Matsuda, Lumi Negishi, Akiko Takahashi, Atsushi Yamagata, Sakurako Goto-Ito, Masaki Mishima, Yutaka Ito, Toshihiko Oka, Keiji Tanaka, Shuya Fukai

Sci Rep. 2018; 8: 10382. Published online 2018 Jul 10. doi: 10.1038/s41598-018-28656-8

PMCID:: PMC6039469

Article PDF–2.1M

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