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Select item 110270921.

Male-Dominant Effects of Chd8 Haploinsufficiency on Synaptic Phenotypes during Development in Mouse Prefrontal Cortex

Robert A. Ellingford, Mizuki Tojo, M. Albert Basson, Laura C. Andreae

ACS Chem Neurosci. 2024 Apr 17; 15(8): 1635–1642. Published online 2024 Apr 1. doi: 10.1021/acschemneuro.3c00690

PMCID:: PMC11027092

Article PDF–4.4M

Select item 109828102.

Chd8 haploinsufficiency impacts rearing experience in C57BL/6 mice

Manal Tabbaa, Pat Levitt

Genes Brain Behav. 2024 Apr; 23(2): e12892. Published online 2024 Apr 1. doi: 10.1111/gbb.12892

PMCID:: PMC10982810

Article PDF–6.3M

Select item 105456713.

CHD8 regulates gut epithelial cell function and affects autism-related behaviors through the gut-brain axis

Ipsita Chatterjee, Dmitriy Getselter, Nasreen Ghanayem, Ram Harari, Liron Davis, Shai Bel, Evan Elliott

Transl Psychiatry. 2023; 13: 305. Published online 2023 Oct 2. doi: 10.1038/s41398-023-02611-2

PMCID:: PMC10545671

Article PDF–4.9M

Select item 102385094.

Deletion of the autism-related gene Chd8 alters activity-dependent transcriptional responses in mouse postmitotic neurons

Atsuki Kawamura, Masaaki Nishiyama

Commun Biol. 2023; 6: 593. Published online 2023 Jun 2. doi: 10.1038/s42003-023-04968-y

PMCID:: PMC10238509

Article PDF–5.5M

Select item 99787795.

Age-differential sexual dimorphisms in CHD8-S62X-mutant mouse synapses and transcriptomes

Soo Yeon Lee, Hanseul Kweon, Hyojin Kang, Eunjoon Kim

Front Mol Neurosci. 2023; 16: 1111388. Published online 2023 Feb 16. doi: 10.3389/fnmol.2023.1111388

PMCID:: PMC9978779

Article PDF–4.0M

Select item 99602956.

Mouse population genetics phenocopies heterogeneity of human Chd8 haploinsufficiency

Manal Tabbaa, Allison Knoll, Pat Levitt

Neuron. Author manuscript; available in PMC 2024 Feb 15.

Published in final edited form as: Neuron. 2023 Feb 15; 111(4): 539–556.e5. Published online 2023 Feb 3. doi: 10.1016/j.neuron.2023.01.009

PMCID:: PMC9960295

Article PDF–4.7M

Select item 96412507.

Age-differential sexual dimorphism in CHD8-S62X-mutant mouse behaviors

Soo Yeon Lee, Hanseul Kweon, Hyojin Kang, Eunjoon Kim

Front Mol Neurosci. 2022; 15: 1022306. Published online 2022 Oct 25. doi: 10.3389/fnmol.2022.1022306

PMCID:: PMC9641250

Article PDF–5.3M

Select item 93024518.

Autism-associated chromatin remodeler CHD8 regulates erythroblast cytokinesis and fine-tunes the balance of Rho GTPase signaling

Zhaowei Tu, Cuiqing Fan, Ashely K. Davis, Mengwen Hu, Chen Wang, Akhila Dandamudi, Katie G. Seu, Theodosia A. Kalfa, Q. Richard Lu, Yi Zheng

Cell Rep. Author manuscript; available in PMC 2022 Jul 21.

Published in final edited form as: Cell Rep. 2022 Jul 12; 40(2): 111072. doi: 10.1016/j.celrep.2022.111072

PMCID:: PMC9302451

Article PDF–2.6M

Select item 89758599.

Developmental pyrethroid exposure and age influence phenotypes in a Chd8 haploinsufficient autism mouse model

Jessica A. Jiménez, Jeremy M. Simon, Wenxin Hu, Sheryl S. Moy, Kathryn M. Harper, Chih-Wei Liu, Kun Lu, Mark J. Zylka

Sci Rep. 2022; 12: 5555. Published online 2022 Apr 1. doi: 10.1038/s41598-022-09533-x

PMCID:: PMC8975859

Article PDF–1.6M

Select item 808802410.

Oxytocin ameliorates impaired social behavior in a Chd8 haploinsufficiency mouse model of autism

Stanislav M. Cherepanov, Maria Gerasimenko, Teruko Yuhi, Kazumi Furuhara, Chiharu Tsuji, Shigeru Yokoyama, Keiichi I. Nakayama, Masaaki Nishiyama, Haruhiro Higashida

BMC Neurosci. 2021; 22: 32. Published online 2021 May 1. doi: 10.1186/s12868-021-00631-6

PMCID:: PMC8088024

Article PDF–1.3M

Select item 805020811.

Chd8 regulates X chromosome inactivation in mouse through fine-tuning control of Xist expression

Andrea Cerase, Alexander N. Young, Nerea Blanes Ruiz, Andreas Buness, Gabrielle M. Sant, Mirjam Arnold, Monica Di Giacomo, Michela Ascolani, Manish Kumar, Andreas Hierholzer, Giuseppe Trigiante, Sarah J. Marzi, Philip Avner

Commun Biol. 2021; 4: 485. Published online 2021 Apr 15. doi: 10.1038/s42003-021-01945-1

PMCID:: PMC8050208

Article PDF–3.8M

Select item 796892512.

TWIST1 and chromatin regulatory proteins interact to guide neural crest cell differentiation

Xiaochen Fan, V Pragathi Masamsetti, Jane QJ Sun, Kasper Engholm-Keller, Pierre Osteil, Joshua Studdert, Mark E Graham, Nicolas Fossat, Patrick PL Tam

eLife. 2021; 10: e62873. Published online 2021 Feb 8. doi: 10.7554/eLife.62873

PMCID:: PMC7968925

Article PDF–4.0M

Select item 778038413.

Controlling litter effects to enhance rigor and reproducibility with rodent models of neurodevelopmental disorders

Jessica A. Jiménez, Mark J. Zylka

J Neurodev Disord. 2021; 13: 2. Published online 2021 Jan 4. doi: 10.1186/s11689-020-09353-y

PMCID:: PMC7780384

Article PDF–1.1M

Select item 778028914.

A Novel Chd8 Mutant Mouse Displays Altered Ultrasonic Vocalizations and Enhanced Motor Coordination

Samuel W. Hulbert, Xiaoming Wang, Simisola O. Gbadegesin, Qiong Xu, Xiu Xu, Yong-Hui Jiang

Autism Res. Author manuscript; available in PMC 2021 Jan 4.

Published in final edited form as: Autism Res. 2020 Oct; 13(10): 1685–1697. Published online 2020 Aug 19. doi: 10.1002/aur.2353

PMCID:: PMC7780289

Article PDF–1.0M

Select item 753710115.

Chd8 haploinsufficiency impairs early brain development and protein homeostasis later in life

Jessica A. Jiménez, Travis S. Ptacek, Alex H. Tuttle, Ralf S. Schmid, Sheryl S. Moy, Jeremy M. Simon, Mark J. Zylka

Mol Autism. 2020; 11: 74. Published online 2020 Oct 5. doi: 10.1186/s13229-020-00369-8

Correction in:: Mol Autism. 2021; 12: 33.

PMCID:: PMC7537101

Article PDF–3.0M

Select item 748676516.

CHD8 dosage regulates transcription in pluripotency and early murine neural differentiation

Sabina Sood, Christopher M. Weber, H. Courtney Hodges, Andrey Krokhotin, Aryaman Shalizi, Gerald R. Crabtree

Proc Natl Acad Sci U S A. 2020 Sep 8; 117(36): 22331–22340. Published online 2020 Aug 24. doi: 10.1073/pnas.1921963117

PMCID:: PMC7486765

Article PDF–1.9M

Select item 665768117.

Infraslow State Fluctuations Govern Spontaneous fMRI Network Dynamics

Daniel Gutierrez-Barragan, M. Albert Basson, Stefano Panzeri, Alessandro Gozzi

Curr Biol. 2019 Jul 22; 29(14): 2295–2306.e5. doi: 10.1016/j.cub.2019.06.017

PMCID:: PMC6657681

Article

Select item 538688718.

Chd8 mediates cortical neurogenesis via transcriptional regulation of cell cycle and Wnt signaling

Omer Durak, Fan Gao, Yea Jin Kaeser-Woo, Richard Rueda, Anthony J. Martorell, Alexi Nott, Carol Y. Liu, L. Ashley Watson, Li-Huei Tsai

Nat Neurosci. Author manuscript; available in PMC 2017 Apr 11.

Published in final edited form as: Nat Neurosci. 2016 Nov; 19(11): 1477–1488. Published online 2016 Oct 3. doi: 10.1038/nn.4400

PMCID:: PMC5386887

Article PDF–3.0M

Select item 465447619.

The Chromatin Regulator CHD8 Is a Context-Dependent Mediator of Cell Survival in Murine Hematopoietic Malignancies

Jennifer R. Shingleton, Michael T. Hemann

PLoS One. 2015; 10(11): e0143275. Published online 2015 Nov 20. doi: 10.1371/journal.pone.0143275

PMCID:: PMC4654476

Article PDF–3.5M

Select item 1105918920.

Life-long Restructuring of 3D Genome Architecture in Cerebellar Granule Cells

Longzhi Tan, Jenny Shi, Siavash Moghadami, Bibudha Parasar, Cydney P. Wright, Yunji Seo, Kristen Vallejo, Inma Cobos, Laramie Duncan, Ritchie Chen, Karl Deisseroth

Science. Author manuscript; available in PMC 2024 Apr 29.

Published in final edited form as: Science. 2023 Sep 8; 381(6662): 1112–1119. Published online 2023 Sep 7. doi: 10.1126/science.adh3253