PMC Links for Gene (Select 67800) - PMC

François R. Jornayvaz, Andreas L. Birkenfeld, Michael J. Jurczak, Shoichi Kanda, Blas A. Guigni, Debbie C. Jiang, Dongyan Zhang, Hui-Young Lee, Varman T. Samuel, Gerald I. Shulman

Proc Natl Acad Sci U S A. 2011 Apr 5; 108(14): 5748–5752. Published online 2011 Mar 21. doi: 10.1073/pnas.1103451108

PMCID:: PMC3078388

Abstract Article PDF–1.1M

Select item 109397424.

DGAT2 inhibition blocks SREBP-1 cleavage and improves hepatic steatosis by increasing phosphatidylethanolamine in the ER

Shunxing Rong, Mingfeng Xia, Goncalo Vale, Simeng Wang, Chai-Wan Kim, Shili Li, Jeffrey G. McDonald, Arun Radhakrishnan, Jay D. Horton

Cell Metab. Author manuscript; available in PMC 2024 Mar 14.

Published in final edited form as: Cell Metab. 2024 Mar 5; 36(3): 617–629.e7. Published online 2024 Feb 9. doi: 10.1016/j.cmet.2024.01.011

PMCID:: PMC10939742

Abstract Article PDF–1.7M

Select item 85399915.

Histone Demethylase KDM7A Contributes to the Development of Hepatic Steatosis by Targeting Diacylglycerol Acyltransferase 2

Ji-Hyun Kim, Arukumar Nagappan, Dae Young Jung, Nanjoo Suh, Myeong Ho Jung

Int J Mol Sci. 2021 Oct; 22(20): 11085. Published online 2021 Oct 14. doi: 10.3390/ijms222011085

PMCID:: PMC8539991

Abstract Article PDF–3.0M

Select item 76966566.

Lipid Droplets in Brown Adipose Tissue Are Dispensable for Cold-Induced Thermogenesis

Chandramohan Chitraju, Alexander W. Fischer, Robert V. Farese, Jr., Tobias C. Walther

Cell Rep. Author manuscript; available in PMC 2020 Nov 28.

Published in final edited form as: Cell Rep. 2020 Nov 3; 33(5): 108348. doi: 10.1016/j.celrep.2020.108348

PMCID:: PMC7696656

Abstract Article PDF–1.6M

Select item 68939137.

Hepatocyte Deletion of Triglyceride-Synthesis Enzyme Acyl CoA: Diacylglycerol Acyltransferase 2 Reduces Steatosis Without Increasing Inflammation or Fibrosis in Mice

Nina L. Gluchowski, Katlyn R. Gabriel, Chandramohan Chitraju, Roderick T. Bronson, Niklas Mejhert, Sebastian Boland, Kun Wang, Zon Weng Lai, Robert V. Farese, Jr., Tobias C. Walther

Hepatology. Author manuscript; available in PMC 2019 Dec 5.

Published in final edited form as: Hepatology. 2019 Dec; 70(6): 1972–1985. Published online 2019 Jun 26. doi: 10.1002/hep.30765

PMCID:: PMC6893913

Abstract Article PDF–2.2M

Select item 63142588.

Hepatic VLDL secretion: DGAT1 determines particle size but not particle number, which can be supported entirely by DGAT2

Zehra Irshad, Nikola Chmel, Raghu Adya, Victor A. Zammit

J Lipid Res. 2019 Jan; 60(1): 111–120. Published online 2018 Nov 5. doi: 10.1194/jlr.M089300

PMCID:: PMC6314258

Abstract Article PDF–952K

Select item 55032149.

Dgat1 and Dgat2 regulate enterocyte triacylglycerol distribution and alter proteins associated with cytoplasmic lipid droplets in response to dietary fat

Yu-Han Hung, Alicia L. Carreiro, Kimberly K. Buhman

Biochim Biophys Acta. Author manuscript; available in PMC 2018 Jun 1.

Published in final edited form as: Biochim Biophys Acta. 2017 Jun; 1862(6): 600–614. Published online 2017 Feb 27. doi: 10.1016/j.bbalip.2017.02.014

PMCID:: PMC5503214

Abstract Article PDF–2.0M

Select item 523470810.

Diacylglycerol acyltransferase 2 links glucose utilization to fatty acid oxidation in the brown adipocytes

Zehra Irshad, Federica Dimitri, Mark Christian, Victor A. Zammit

J Lipid Res. 2017 Jan; 58(1): 15–30. Published online 2016 Dec 29. doi: 10.1194/jlr.M068197

PMCID:: PMC5234708

Abstract Article PDF–1.6M

Select item 431157111.

Intestinal acyl-CoA:diacylglycerol acyltransferase 2 overexpression enhances postprandial triglyceridemic response and exacerbates high fat diet-induced hepatic triacylglycerol storage

Aki Uchida, Mikhail N. Slipchenko, Trisha Eustaquio, James F. Leary, Ji-Xin Cheng, Kimberly K. Buhman

Biochim Biophys Acta. Author manuscript; available in PMC 2015 Jan 30.

Published in final edited form as: Biochim Biophys Acta. 2013 Aug; 1831(8): 1377–1385. Published online 2013 May 2. doi: 10.1016/j.bbalip.2013.04.013

PMCID:: PMC4311571

Abstract Article PDF–1.2M

Select item 315106812.

Murine Diacylglycerol Acyltransferase-2 (DGAT2) Can Catalyze Triacylglycerol Synthesis and Promote Lipid Droplet Formation Independent of Its Localization to the Endoplasmic Reticulum

Pamela J. McFie, Shanna L. Banman, Steven Kary, Scot J. Stone

J Biol Chem. 2011 Aug 12; 286(32): 28235–28246. Published online 2011 Jun 16. doi: 10.1074/jbc.M111.256008

PMCID:: PMC3151068

Abstract Article PDF–3.5M

Select item 295255613.

Involvement and mechanism of DGAT2 upregulation in the pathogenesis of alcoholic fatty liver disease

Zhigang Wang, Tong Yao, Zhenyuan Song

J Lipid Res. 2010 Nov; 51(11): 3158–3165. doi: 10.1194/jlr.M007948

PMCID:: PMC2952556

Abstract Article PDF–905K

Select item 842374914.

Deficiency of intestinal Bmal1 prevents obesity induced by high-fat feeding

Fangjun Yu, Zhigang Wang, Tianpeng Zhang, Xun Chen, Haiman Xu, Fei Wang, Lianxia Guo, Min Chen, Kaisheng Liu, Baojian Wu

Nat Commun. 2021; 12: 5323. Published online 2021 Sep 7. doi: 10.1038/s41467-021-25674-5

PMCID:: PMC8423749

Abstract Article PDF–2.4M

Select item 772224315.

CTRP12 inhibits triglyceride synthesis and export in hepatocytes by suppressing HNF-4α and DGAT2 expression

Stefanie Y. Tan, Hannah C. Little, Dylan C. Sarver, Paul A. Watkins, G. William Wong

FEBS Lett. Author manuscript; available in PMC 2020 Dec 8.

Published in final edited form as: FEBS Lett. 2020 Oct; 594(19): 3227–3239. Published online 2020 Aug 14. doi: 10.1002/1873-3468.13895

PMCID:: PMC7722243

Abstract Article PDF–1.0M

Select item 730522916.

The Role of Bone Morphogenetic Protein Signaling in Non-Alcoholic Fatty Liver Disease

Timothy E. Thayer, Christian L. Lino Cardenas, Trejeeve Martyn, Christopher J. Nicholson, Lisa Traeger, Florian Wunderer, Charles Slocum, Haakon Sigurslid, Hannah R. Shakartzi, Caitlin O’Rourke, Georgia Shelton, Mary D. Buswell, Hanna Barnes, Leif R. Neitzel, Clara D. Ledsky, Jason Pingcheng Li, Megan F. Burke, Eric Farber-Eger, Daniel S. Perrien, Ravindra Kumar, Kathleen E. Corey, Quinn S. Wells, Kenneth D. Bloch, Charles C. Hong, Donald B. Bloch, Rajeev Malhotra

Sci Rep. 2020; 10: 9831. Published online 2020 Jun 19. doi: 10.1038/s41598-020-66770-8

PMCID:: PMC7305229

Abstract Article PDF–5.0M

Select item 586287917.

The Role of Diacylglycerol Acyltransferase (DGAT) 1 and 2 in Cardiac Metabolism and Function

Nathan D. Roe, Michal K. Handzlik, Tao Li, Rong Tian

Sci Rep. 2018; 8: 4983. Published online 2018 Mar 21. doi: 10.1038/s41598-018-23223-7

PMCID:: PMC5862879

Abstract Article PDF–2.0M

Select item 332938518.

Rescue of Mtp siRNA-induced hepatic steatosis by DGAT2 siRNA silencing

Samnang Tep, Radu Mihaila, Alexander Freeman, Victoria Pickering, Felicia Huynh, Marija Tadin-Strapps, Allison Stracks, Brian Hubbard, Jeremy Caldwell, W. Michael Flanagan, Nelly A. Kuklin, Brandon Ason

J Lipid Res. 2012 May; 53(5): 859–867. doi: 10.1194/jlr.M021063

Correction in:: J Lipid Res. 2012 Nov; 53(11): 2484.

PMCID:: PMC3329385

Abstract Article PDF–1.4M

Select item 383745819.

DGAT enzymes and triacylglycerol biosynthesis

Chi-Liang Eric Yen, Scot J. Stone, Suneil Koliwad, Charles Harris, Robert V. Farese, Jr.

J Lipid Res. 2008 Nov; 49(11): 2283–2301. Published online 2008 Aug 29. doi: 10.1194/jlr.R800018-JLR200

PMCID:: PMC3837458

Abstract Article PDF–1.7M

Select item 351084220.

Studies on the Substrate and Stereo/Regioselectivity of Adipose Triglyceride Lipase, Hormone-sensitive Lipase, and Diacylglycerol-O-acyltransferases

Thomas O. Eichmann, Manju Kumari, Joel T. Haas, Robert V. Farese, Jr., Robert Zimmermann, Achim Lass, Rudolf Zechner

J Biol Chem. 2012 Nov 30; 287(49): 41446–41457. Published online 2012 Oct 12. doi: 10.1074/jbc.M112.400416

PMCID:: PMC3510842

Abstract Article PDF–1.4M

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