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Select item 49623481.

Transcriptome analysis of paired primary colorectal carcinoma and liver metastases reveals fusion transcripts and similar gene expression profiles in primary carcinoma and liver metastases

Ja-Rang Lee, Chae Hwa Kwon, Yuri Choi, Hye Ji Park, Hyun Sung Kim, Hong-Jae Jo, Nahmgun Oh, Do Youn Park

BMC Cancer. 2016; 16: 539. Published online 2016 Jul 26. doi: 10.1186/s12885-016-2596-3

PMCID:: PMC4962348

Article PDF–2.6M

Select item 18510852.

Identification of a regulator of transcription elongation as an accessory factor for the human Mediator coactivator

Sohail Malik, María J. Barrero, Tara Jones

Proc Natl Acad Sci U S A. 2007 Apr 10; 104(15): 6182–6187. Published online 2007 Apr 2. doi: 10.1073/pnas.0608717104

PMCID:: PMC1851085

Article PDF–877K

Select item 4196473.

Functional interactions of RNA-capping enzyme with factors that positively and negatively regulate promoter escape by RNA polymerase II

Subhrangsu S. Mandal, Chun Chu, Tadashi Wada, Hiroshi Handa, Aaron J. Shatkin, Danny Reinberg

Proc Natl Acad Sci U S A. 2004 May 18; 101(20): 7572–7577. Published online 2004 May 10. doi: 10.1073/pnas.0401493101

PMCID:: PMC419647

Article PDF–494K

Select item 33430884.

The DSIF Subunits Spt4 and Spt5 Have Distinct Roles at Various Phases of Immunoglobulin Class Switch Recombination

Andre Stanlie, Nasim A. Begum, Hideo Akiyama, Tasuku Honjo

PLoS Genet. 2012 Apr; 8(4): e1002675. Published online 2012 Apr 26. doi: 10.1371/journal.pgen.1002675

PMCID:: PMC3343088

Article PDF–862K

Select item 27883315.

DSIF, the Paf1 complex, and Tat-SF1 have nonredundant, cooperative roles in RNA polymerase II elongation

Yexi Chen, Yuki Yamaguchi, Yuta Tsugeno, Junichi Yamamoto, Tomoko Yamada, Mitsuhiro Nakamura, Koji Hisatake, Hiroshi Handa

Genes Dev. 2009 Dec 1; 23(23): 2765–2777. doi: 10.1101/gad.1834709

PMCID:: PMC2788331

Article PDF–1.0M

Select item 12576896.

A negative elongation factor for human RNA polymerase II inhibits the anti-arrest transcript-cleavage factor TFIIS

Murali Palangat, Dan B. Renner, David H. Price, Robert Landick

Proc Natl Acad Sci U S A. 2005 Oct 18; 102(42): 15036–15041. Published online 2005 Oct 7. doi: 10.1073/pnas.0409405102

PMCID:: PMC1257689

Article PDF–639K

Select item 3816657.

Human Spt6 Stimulates Transcription Elongation by RNA Polymerase II In Vitro

Masaki Endoh, Wenyan Zhu, Jun Hasegawa, Hajime Watanabe, Dong-Ki Kim, Masatoshi Aida, Naoto Inukai, Takashi Narita, Tomoko Yamada, Akiko Furuya, Hiroe Sato, Yuki Yamaguchi, Subhrangsu S. Mandal, Danny Reinberg, Tadashi Wada, Hiroshi Handa

Mol Cell Biol. 2004 Apr; 24(8): 3324–3336. doi: 10.1128/MCB.24.8.3324-3336.2004

PMCID:: PMC381665

Article PDF–736K

Select item 2312778.

Identification and analysis of a functional human homolog of the SPT4 gene of Saccharomyces cerevisiae.

G A Hartzog, M A Basrai, S L Ricupero-Hovasse, P Hieter, F Winston

Mol Cell Biol. 1996 Jun; 16(6): 2848–2856. doi: 10.1128/mcb.16.6.2848

PMCID:: PMC231277

Summary PDF–616K

Select item 58230259.

Spt4 selectively regulates the expression of C9orf72 sense and antisense mutant transcripts associated with c9FTD/ALS

Nicholas J. Kramer, Yari Carlomagno, Yong-Jie Zhang, Sandra Almeida, Casey N. Cook, Tania F. Gendron, Mercedes Prudencio, Marka Van Blitterswijk, Veronique Belzil, Julien Couthouis, Joseph West Paul, III, Lindsey D. Goodman, Lillian Daughrity, Jeannie Chew, Aliesha Garrett, Luc Pregent, Karen Jansen-West, Lilia J. Tabassian, Rosa Rademakers, Kevin Boylan, Neill R. Graff-Radford, Keith A. Josephs, Joseph E. Parisi, David S. Knopman, Ronald C. Petersen, Bradley F. Boeve, Ning Deng, Yanan Feng, Tzu-Hao Cheng, Dennis W. Dickson, Stanley N. Cohen, Nancy M. Bonini, Christopher D. Link, Fen-Biao Gao, Leonard Petrucelli, Aaron D. Gitler

Science. Author manuscript; available in PMC 2018 Feb 22.

Published in final edited form as: Science. 2016 Aug 12; 353(6300): 708–712. doi: 10.1126/science.aaf7791

PMCID:: PMC5823025

Article PDF–778K

Select item 117108410.

Evidence that P-TEFb alleviates the negative effect of DSIF on RNA polymerase II-dependent transcription in vitro.

T Wada, T Takagi, Y Yamaguchi, D Watanabe, H Handa

EMBO J. 1998 Dec 15; 17(24): 7395–7403. doi: 10.1093/emboj/17.24.7395

PMCID:: PMC1171084

Summary PDF–384K

Select item 13473311.

Subnuclear Localization of Ku Protein: Functional Association with RNA Polymerase II Elongation Sites

Xianming Mo, William S. Dynan

Mol Cell Biol. 2002 Nov; 22(22): 8088–8099. doi: 10.1128/MCB.22.22.8088-8099.2002

PMCID:: PMC134733

Article PDF–724K

Select item 195194812.

Differential Regulation of NF-κB by Elongation Factors Is Determined by Core Promoter Type

Liat Amir-Zilberstein, Elena Ainbinder, Leanne Toube, Yuki Yamaguchi, Hiroshi Handa, Rivka Dikstein

Mol Cell Biol. 2007 Jul; 27(14): 5246–5259. Published online 2007 May 14. doi: 10.1128/MCB.00586-07

PMCID:: PMC1951948

Article PDF–926K

Select item 31648013.

DSIF, a novel transcription elongation factor that regulates RNA polymerase II processivity, is composed of human Spt4 and Spt5 homologs

Tadashi Wada, Toshiyuki Takagi, Yuki Yamaguchi, Anwarul Ferdous, Takeshi Imai, Susumu Hirose, Seiji Sugimoto, Keiichi Yano, Grant A. Hartzog, Fred Winston, Stephen Buratowski, Hiroshi Handa

Genes Dev. 1998 Feb 1; 12(3): 343–356. doi: 10.1101/gad.12.3.343

PMCID:: PMC316480

Article PDF–1.1M

Select item 8446214.

Tat-SF1 Protein Associates with RAP30 and Human SPT5 Proteins

Jae B. Kim, Yuki Yamaguchi, Tadashi Wada, Hiroshi Handa, Phillip A. Sharp

Mol Cell Biol. 1999 Sep; 19(9): 5960–5968. doi: 10.1128/mcb.19.9.5960

PMCID:: PMC84462

Article PDF–885K

Select item 267816115.

A transcriptional sketch of a primary human breast cancer by 454 deep sequencing

Alessandro Guffanti, Michele Iacono, Paride Pelucchi, Namshin Kim, Giulia Soldà, Larry J Croft, Ryan J Taft, Ermanno Rizzi, Marjan Askarian-Amiri, Raoul J Bonnal, Maurizio Callari, Flavio Mignone, Graziano Pesole, Giovanni Bertalot, Luigi Rossi Bernardi, Alberto Albertini, Christopher Lee, John S Mattick, Ileana Zucchi, Gianluca De Bellis

BMC Genomics. 2009; 10: 163. Published online 2009 Apr 20. doi: 10.1186/1471-2164-10-163

PMCID:: PMC2678161

Article PDF–1.6M

Select item 14948116.

Human Transcription Elongation Factor NELF: Identification of Novel Subunits and Reconstitution of the Functionally Active Complex

Takashi Narita, Yuki Yamaguchi, Keiichi Yano, Seiji Sugimoto, Sittinan Chanarat, Tadashi Wada, Dong-ki Kim, Jun Hasegawa, Masashi Omori, Naoto Inukai, Masaki Endoh, Tomoko Yamada, Hiroshi Handa

Mol Cell Biol. 2003 Mar; 23(6): 1863–1873. doi: 10.1128/MCB.23.6.1863-1873.2003

PMCID:: PMC149481

Article PDF–570K

Select item 8555717.

Domains in the SPT5 Protein That Modulate Its Transcriptional Regulatory Properties

Dmitri Ivanov, Youn Tae Kwak, Jun Guo, Richard B. Gaynor

Mol Cell Biol. 2000 May; 20(9): 2970–2983. doi: 10.1128/mcb.20.9.2970-2983.2000

PMCID:: PMC85557

Article PDF–1.8M

Select item 375551918.

Deployment of the human immunodeficiency virus type 1 protein arsenal: combating the host to enhance viral transcription and providing targets for therapeutic development

Satinder Dahiya, Michael R. Nonnemacher, Brian Wigdahl

J Gen Virol. 2012 Jun; 93(Pt 6): 1151–1172. doi: 10.1099/vir.0.041186-0

PMCID:: PMC3755519

Article PDF–931K

Select item 889076919.

ELOF1 is a transcription-coupled DNA repair factor that directs RNA polymerase II ubiquitylation

Yana van der Weegen, Klaas de Lint, Diana van den Heuvel, Yuka Nakazawa, Tycho E.T. Mevissen, Janne J.M. van Schie, Marta San Martin Alonso, Daphne E.C. Boer, Román González-Prieto, Ishwarya V. Narayanan, Noud H.M. Klaassen, Annelotte P. Wondergem, Khashayar Roohollahi, Josephine C. Dorsman, Yuichiro Hara, Alfred C.O. Vertegaal, Job de Lange, Johannes C. Walter, Sylvie M. Noordermeer, Mats Ljungman, Tomoo Ogi, Rob M.F. Wolthuis, Martijn S. Luijsterburg

Nat Cell Biol. Author manuscript; available in PMC 2022 Jun 9.

Published in final edited form as: Nat Cell Biol. 2021 Jun; 23(6): 595–607. Published online 2021 Jun 9. doi: 10.1038/s41556-021-00688-9

PMCID:: PMC8890769

Article PDF–7.4M

Select item 426337120.

A Massively Parallel Pipeline to Clone DNA Variants and Examine Molecular Phenotypes of Human Disease Mutations

Xiaomu Wei, Jishnu Das, Robert Fragoza, Jin Liang, Francisco M. Bastos de Oliveira, Hao Ran Lee, Xiujuan Wang, Matthew Mort, Peter D. Stenson, David N. Cooper, Steven M. Lipkin, Marcus B. Smolka, Haiyuan Yu

PLoS Genet. 2014 Dec; 10(12): e1004819. Published online 2014 Dec 11. doi: 10.1371/journal.pgen.1004819

PMCID:: PMC4263371

Article PDF–7.6M

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