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Select item 35335421.

Cancer susceptibility and embryonic lethality in Mob1a/1b double-mutant mice

Miki Nishio, Koichi Hamada, Kohichi Kawahara, Masato Sasaki, Fumihito Noguchi, Shuhei Chiba, Kensaku Mizuno, Satoshi O. Suzuki, Youyi Dong, Masaaki Tokuda, Takumi Morikawa, Hiroki Hikasa, Jonathan Eggenschwiler, Norikazu Yabuta, Hiroshi Nojima, Kentaro Nakagawa, Yutaka Hata, Hiroshi Nishina, Koshi Mimori, Masaki Mori, Takehiko Sasaki, Tak W. Mak, Toru Nakano, Satoshi Itami, Akira Suzuki

J Clin Invest. 2012 Dec 3; 122(12): 4505–4518. Published online 2012 Nov 12. doi: 10.1172/JCI63735

PMCID:: PMC3533542

Article PDF–11M

Select item 85608802.

EGFR Regulates the Hippo pathway by promoting the tyrosine phosphorylation of MOB1

Toshinori Ando, Nadia Arang, Zhiyong Wang, Daniela Elena Costea, Xiaodong Feng, Yusuke Goto, Hiroki Izumi, Mara Gilardi, Kazuyo Ando, J. Silvio Gutkind

Commun Biol. 2021; 4: 1237. Published online 2021 Nov 1. doi: 10.1038/s42003-021-02744-4

PMCID:: PMC8560880

Article PDF–3.4M

Select item 61972433.

Depletion of MOB1A/B causes intestinal epithelial degeneration by suppressing Wnt activity and activating BMP/TGF-β signaling

June Sung Bae, Yoon Jeon, Sun Mi Kim, Ji Yun Jang, Mi Kyung Park, In-Hoo Kim, Deog Su Hwang, Dae-Sik Lim, Ho Lee

Cell Death Dis. 2018 Nov; 9(11): 1083. Published online 2018 Oct 22. doi: 10.1038/s41419-018-1138-0

PMCID:: PMC6197243

Article PDF–1.8M

Select item 70805004.

YAP1 is a potent driver of the onset and progression of oral squamous cell carcinoma

Hirofumi Omori, Miki Nishio, Muneyuki Masuda, Yosuke Miyachi, Fumihito Ueda, Takafumi Nakano, Kuniaki Sato, Koshi Mimori, Kenichi Taguchi, Hiroki Hikasa, Hiroshi Nishina, Hironori Tashiro, Tohru Kiyono, Tak Wah Mak, Kazuwa Nakao, Takashi Nakagawa, Tomohiko Maehama, Akira Suzuki

Sci Adv. 2020 Mar; 6(12): eaay3324. Published online 2020 Mar 18. doi: 10.1126/sciadv.aay3324

Correction in:: Sci Adv. 2023 Dec 15; 9(50): eadn0844.

PMCID:: PMC7080500

Article PDF–3.0M

Select item 26005815.

The Nore1B/Mst1 complex restrains antigen receptor-induced proliferation of naïve T cells

Dawang Zhou, Benjamin D. Medoff, Lanfen Chen, Lequn Li, Xian-feng Zhang, Maria Praskova, Matthew Liu, Aimee Landry, Richard S. Blumberg, Vassiliki A. Boussiotis, Ramnik Xavier, Joseph Avruch

Proc Natl Acad Sci U S A. 2008 Dec 23; 105(51): 20321–20326. Published online 2008 Dec 10. doi: 10.1073/pnas.0810773105

PMCID:: PMC2600581

Article PDF–1.1M

Select item 75410066.

Endogenous YAP1 activation drives immediate onset of cervical carcinoma in situ in mice

Miki Nishio, Yoko To, Tomohiko Maehama, Yukari Aono, Junji Otani, Hiroki Hikasa, Akihiro Kitagawa, Koshi Mimori, Takehiko Sasaki, Hiroshi Nishina, Shinya Toyokuni, John P. Lydon, Kazuwa Nakao, Tak Wah Mak, Tohru Kiyono, Hidetaka Katabuchi, Hironori Tashiro, Akira Suzuki

Cancer Sci. 2020 Oct; 111(10): 3576–3587. Published online 2020 Aug 21. doi: 10.1111/cas.14581

PMCID:: PMC7541006

Article PDF–1.9M

Select item 55042937.

YAP determines the cell fate of injured mouse hepatocytes in vivo

Norio Miyamura, Shoji Hata, Tohru Itoh, Minoru Tanaka, Miki Nishio, Michiko Itoh, Yoshihiro Ogawa, Shuji Terai, Isao Sakaida, Akira Suzuki, Atsushi Miyajima, Hiroshi Nishina

Nat Commun. 2017; 8: 16017. Published online 2017 Jul 6. doi: 10.1038/ncomms16017

Correction in:: Nat Commun. 2017; 8: 16146.

PMCID:: PMC5504293

Article PDF–1.5M

Select item 93038588.

Hippo-TAZ signaling is the master regulator of the onset of triple-negative basal-like breast cancers

Hirotoshi Soyama, Miki Nishio, Junji Otani, Toshiko Sakuma, Shintaro Takao, Shigeo Hara, Takaaki Masuda, Koshi Mimori, Shinya Toyokuni, John P. Lydon, Kazuwa Nakao, Hiroshi Nishina, Takumi Fukumoto, Tomohiko Maehama, Akira Suzuki

Proc Natl Acad Sci U S A. 2022 Jul 19; 119(29): e2123134119. Published online 2022 Jul 11. doi: 10.1073/pnas.2123134119

PMCID:: PMC9303858

Article PDF–2.8M

Select item 47118269.

Dysregulated YAP1/TAZ and TGF-β signaling mediate hepatocarcinogenesis in Mob1a/1b-deficient mice

Miki Nishio, Keishi Sugimachi, Hiroki Goto, Jia Wang, Takumi Morikawa, Yosuke Miyachi, Yusuke Takano, Hiroki Hikasa, Tohru Itoh, Satoshi O. Suzuki, Hiroki Kurihara, Shinichi Aishima, Andrew Leask, Takehiko Sasaki, Toru Nakano, Hiroshi Nishina, Yuji Nishikawa, Yoshitaka Sekido, Kazuwa Nakao, Kazuo Shin-ya, Koshi Mimori, Akira Suzuki

Proc Natl Acad Sci U S A. 2016 Jan 5; 113(1): E71–E80. Published online 2015 Dec 22. doi: 10.1073/pnas.1517188113

PMCID:: PMC4711826

Article PDF–2.6M

Select item 468254810.

MOBKL1A/MOBKL1B Phosphorylation by MST1 and MST2 Inhibits Cell Proliferation

Maria Praskova, Fan Xia, Joseph Avruch

Curr Biol. Author manuscript; available in PMC 2015 Dec 17.

Published in final edited form as: Curr Biol. 2008 Mar 11; 18(5): 311–321. doi: 10.1016/j.cub.2008.02.006

PMCID:: PMC4682548

Article PDF–1.1M

Select item 629531311.

A microRNA-Hippo pathway that promotes cardiomyocyte proliferation and cardiac regeneration in mice

Ying Tian, Ying Liu, Tao Wang, Ning Zhou, Jun Kong, Li Chen, Melinda Snitow, Michael Morley, Deqiang Li, Nataliya Petrenko, Su Zhou, Minmin Lu, Erhe Gao, Walter J. Koch, Kathleen M. Stewart, Edward E. Morrisey

Sci Transl Med. Author manuscript; available in PMC 2018 Dec 16.

Published in final edited form as: Sci Transl Med. 2015 Mar 18; 7(279): 279ra38. doi: 10.1126/scitranslmed.3010841

PMCID:: PMC6295313

Article PDF–2.7M

Select item 592490512.

Neddylation mediates ventricular chamber maturation through repression of Hippo signaling

Jianqiu Zou, Wenxia Ma, Jie Li, Rodney Littlejohn, Hongyi Zhou, Il-man Kim, David J. R. Fulton, Weiqin Chen, Neal L. Weintraub, Jiliang Zhou, Huabo Su

Proc Natl Acad Sci U S A. 2018 Apr 24; 115(17): E4101–E4110. Published online 2018 Apr 9. doi: 10.1073/pnas.1719309115

PMCID:: PMC5924905

Article PDF–2.3M

Select item 18788513.

A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome

Jens Hansen, Thomas Floss, Petra Van Sloun, Ernst-Martin Füchtbauer, Franz Vauti, Hans-Hennig Arnold, Frank Schnütgen, Wolfgang Wurst, Harald von Melchner, Patricia Ruiz

Proc Natl Acad Sci U S A. 2003 Aug 19; 100(17): 9918–9922. Published online 2003 Aug 6. doi: 10.1073/pnas.1633296100

PMCID:: PMC187885

Article PDF–287K

Select item 16551114.

BayGenomics: a resource of insertional mutations in mouse embryonic stem cells

Doug Stryke, Michiko Kawamoto, Conrad C. Huang, Susan J. Johns, Leslie A. King, Courtney A. Harper, Elaine C. Meng, Roy E. Lee, Alice Yee, Larry L'Italien, Pao-Tien Chuang, Stephen G. Young, William C. Skarnes, Patricia C. Babbitt, Thomas E. Ferrin

Nucleic Acids Res. 2003 Jan 1; 31(1): 278–281. doi: 10.1093/nar/gkg064

PMCID:: PMC165511

Article PDF–217K

Select item 1683315.

Genome-wide expression profiling of mid-gestation placenta and embryo using a 15,000 mouse developmental cDNA microarray

Tetsuya S. Tanaka, Saied A. Jaradat, Meng K. Lim, George J. Kargul, Xiaohong Wang, Marija J. Grahovac, Serafino Pantano, Yuri Sano, Yulan Piao, Ramaiah Nagaraja, Hirofumi Doi, William H. Wood, III, Kevin G. Becker, Minoru S. H. Ko

Proc Natl Acad Sci U S A. 2000 Aug 1; 97(16): 9127–9132. doi: 10.1073/pnas.97.16.9127

PMCID:: PMC16833

Article PDF–847K

Select item 255627016.

Large-scale gene trapping in C57BL/6N mouse embryonic stem cells

Gwenn M. Hansen, Diane C. Markesich, Michael B. Burnett, Qichao Zhu, Karen M. Dionne, Lizabeth J. Richter, Richard H. Finnell, Arthur T. Sands, Brian P. Zambrowicz, Alejandro Abuin

Genome Res. 2008 Oct; 18(10): 1670–1679. doi: 10.1101/gr.078352.108

PMCID:: PMC2556270

Article PDF–493K

Select item 28355417.

Wnk1 kinase deficiency lowers blood pressure in mice: A gene-trap screen to identify potential targets for therapeutic intervention

Brian P. Zambrowicz, Alejandro Abuin, Ramiro Ramirez-Solis, Lizabeth J. Richter, James Piggott, Hector BeltrandelRio, Eric C. Buxton, Joel Edwards, Rick A. Finch, Carl J. Friddle, Anupma Gupta, Gwenn Hansen, Yi Hu, Wenhu Huang, Crystal Jaing, Billie Wayne Key, Jr., Peter Kipp, Buckley Kohlhauff, Zhi-Qing Ma, Diane Markesich, Robert Payne, David G. Potter, Ny Qian, Joseph Shaw, Jeff Schrick, Zheng-Zheng Shi, Mary Jean Sparks, Isaac Van Sligtenhorst, Peter Vogel, Wade Walke, Nianhua Xu, Qichao Zhu, Christophe Person, Arthur T. Sands

Proc Natl Acad Sci U S A. 2003 Nov 25; 100(24): 14109–14114. Published online 2003 Nov 10. doi: 10.1073/pnas.2336103100

Correction in:: Proc Natl Acad Sci U S A. 2004 Mar 23; 101(12): 4332.

PMCID:: PMC283554

Article PDF–481K

Select item 302253418.

A High-Resolution Anatomical Atlas of the Transcriptome in the Mouse Embryo

Graciana Diez-Roux, Sandro Banfi, Marc Sultan, Lars Geffers, Santosh Anand, David Rozado, Alon Magen, Elena Canidio, Massimiliano Pagani, Ivana Peluso, Nathalie Lin-Marq, Muriel Koch, Marchesa Bilio, Immacolata Cantiello, Roberta Verde, Cristian De Masi, Salvatore A. Bianchi, Juliette Cicchini, Elodie Perroud, Shprese Mehmeti, Emilie Dagand, Sabine Schrinner, Asja Nürnberger, Katja Schmidt, Katja Metz, Christina Zwingmann, Norbert Brieske, Cindy Springer, Ana Martinez Hernandez, Sarah Herzog, Frauke Grabbe, Cornelia Sieverding, Barbara Fischer, Kathrin Schrader, Maren Brockmeyer, Sarah Dettmer, Christin Helbig, Violaine Alunni, Marie-Annick Battaini, Carole Mura, Charlotte N. Henrichsen, Raquel Garcia-Lopez, Diego Echevarria, Eduardo Puelles, Elena Garcia-Calero, Stefan Kruse, Markus Uhr, Christine Kauck, Guangjie Feng, Nestor Milyaev, Chuang Kee Ong, Lalit Kumar, MeiSze Lam, Colin A. Semple, Attila Gyenesei, Stefan Mundlos, Uwe Radelof, Hans Lehrach, Paolo Sarmientos, Alexandre Reymond, Duncan R. Davidson, Pascal Dollé, Stylianos E. Antonarakis, Marie-Laure Yaspo, Salvador Martinez, Richard A. Baldock, Gregor Eichele, Andrea Ballabio

PLoS Biol. 2011 Jan; 9(1): e1000582. Published online 2011 Jan 18. doi: 10.1371/journal.pbio.1000582

PMCID:: PMC3022534

Article PDF–3.8M

Select item 31099219.

RIKEN Integrated Sequence Analysis (RISA) System—384-Format Sequencing Pipeline with 384 Multicapillary Sequencer

Kazuhiro Shibata, Masayoshi Itoh, Katsunori Aizawa, Sumiharu Nagaoka, Nobuya Sasaki, Piero Carninci, Hideaki Konno, Junichi Akiyama, Katsuo Nishi, Tokuji Kitsunai, Hideo Tashiro, Mari Itoh, Noriko Sumi, Yoshiyuki Ishii, Shin Nakamura, Makoto Hazama, Tsutomu Nishine, Akira Harada, Rintaro Yamamoto, Hiroyuki Matsumoto, Sumito Sakaguchi, Takashi Ikegami, Katsuya Kashiwagi, Syuji Fujiwake, Kouji Inoue, Yoshiyuki Togawa, Masaki Izawa, Eiji Ohara, Masanori Watahiki, Yuko Yoneda, Tomokazu Ishikawa, Kaori Ozawa, Takumi Tanaka, Shuji Matsuura, Jun Kawai, Yasushi Okazaki, Masami Muramatsu, Yorinao Inoue, Akira Kira, Yoshihide Hayashizaki

Genome Res. 2000 Nov; 10(11): 1757–1771. doi: 10.1101/gr.152600

PMCID:: PMC310992

Article PDF–3.4M

Select item 31098020.

Normalization and Subtraction of Cap-Trapper-Selected cDNAs to Prepare Full-Length cDNA Libraries for Rapid Discovery of New Genes

Piero Carninci, Yuko Shibata, Norihito Hayatsu, Yuichi Sugahara, Kazuhiro Shibata, Masayoshi Itoh, Hideaki Konno, Yasushi Okazaki, Masami Muramatsu, Yoshihide Hayashizaki

Genome Res. 2000 Oct; 10(10): 1617–1630. doi: 10.1101/gr.145100

PMCID:: PMC310980

Article PDF–1.4M

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