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Select item 85081441.

Tyrp1 Mutant Variants Associated with OCA3: Computational Characterization of Protein Stability and Ligand Binding

Milan H. Patel, Monika B. Dolinska, Yuri V. Sergeev

Int J Mol Sci. 2021 Oct; 22(19): 10203. Published online 2021 Sep 22. doi: 10.3390/ijms221910203

PMCID:: PMC8508144

Abstract Article PDF–4.7M

Select item 69816192.

Protein Stability and Functional Characterization of Intra-Melanosomal Domain of Human Recombinant Tyrosinase-Related Protein 1

Monika B. Dolinska, Kenneth L. Young, II, Claudia Kassouf, Emilios K. Dimitriadis, Paul T. Wingfield, Yuri V. Sergeev

Int J Mol Sci. 2020 Jan; 21(1): 331. Published online 2020 Jan 3. doi: 10.3390/ijms21010331

PMCID:: PMC6981619

Abstract Article PDF–2.8M

Select item 55282783.

Tyrosinase related protein 1 (TYRP1/gp75) in human cutaneous melanoma

Ghanem Ghanem, Journé Fabrice

Mol Oncol. 2011 Apr; 5(2): 150–155. Published online 2011 Feb 3. doi: 10.1016/j.molonc.2011.01.006

PMCID:: PMC5528278

Abstract Article PDF–178K

Select item 37037944.

In Silico Screening and Molecular Dynamics Simulation of Disease-Associated nsSNP in TYRP1 Gene and Its Structural Consequences in OCA3

Balu Kamaraj, Rituraj Purohit

Biomed Res Int. 2013; 2013: 697051. Published online 2013 Jun 19. doi: 10.1155/2013/697051

PMCID:: PMC3703794

Abstract Article PDF–3.3M

Select item 36684755.

Tyrosinase-related protein 1 mRNA expression in lymph node metastases predicts overall survival in high-risk melanoma patients

P El Hajj, F Journe, M Wiedig, I Laios, F Salès, M-D Galibert, L C Van Kempen, A Spatz, B Badran, D Larsimont, A Awada, G Ghanem

Br J Cancer. 2013 Apr 30; 108(8): 1641–1647. Published online 2013 Mar 21. doi: 10.1038/bjc.2013.115

PMCID:: PMC3668475

Abstract Article PDF–392K

Select item 32426086.

TYRP1 mRNA expression in melanoma metastases correlates with clinical outcome

F Journe, H Id Boufker, L Van Kempen, M-D Galibert, M Wiedig, F Salès, A Theunis, D Nonclercq, A Frau, G Laurent, A Awada, G Ghanem

Br J Cancer. 2011 Nov 22; 105(11): 1726–1732. Published online 2011 Nov 1. doi: 10.1038/bjc.2011.451

PMCID:: PMC3242608

Abstract Article PDF–481K

Select item 21878487.

The melanoma antigen gp75 is the human homologue of the mouse b (brown) locus gene product

J Exp Med. 1990 Apr 1; 171(4): 1375–1380. doi: 10.1084/jem.171.4.1375

PMCID:: PMC2187848

Summary PDF–390K

Select item 17801958.

A Role for Tyrosinase-Related Protein 1 in 4-tert-Butylphenol-Induced Toxicity in Melanocytes : Implications for Vitiligo

Prashiela Manga, David Sheyn, Fan Yang, Rangaprasad Sarangarajan, Raymond E. Boissy

Am J Pathol. 2006 Nov; 169(5): 1652–1662. doi: 10.2353/ajpath.2006.050769

PMCID:: PMC1780195

Abstract Article PDF–1.2M

Select item 17160319.

Rufous oculocutaneous albinism in southern African Blacks is caused by mutations in the TYRP1 gene.

P Manga, J G Kromberg, N F Box, R A Sturm, T Jenkins, M Ramsay

Am J Hum Genet. 1997 Nov; 61(5): 1095–1101. doi: 10.1086/301603

PMCID:: PMC1716031

Summary Page Browse PDF–1.3M

Select item 33374410.

A two allele XbaI RFLP at the catalase 2 locus

M.-A. Colman, S. Shibahara, B. Kwon, T. Jenkins, M. Ramsay

Nucleic Acids Res. 1991 Feb 25; 19(4): 960. doi: 10.1093/nar/19.4.960-a

PMCID:: PMC333744

Summary Page Browse PDF–178K

Select item 33076811.

Nucleotide sequence of the cDNA encoding human tyrosinase-related protein.

T Cohen, R M Muller, Y Tomita, S Shibahara

Nucleic Acids Res. 1990 May 11; 18(9): 2807–2808. doi: 10.1093/nar/18.9.2807

PMCID:: PMC330768

Summary Page Browse PDF–225K

Select item 32901712.

Human tyrosinase-like protein (TYRL) carboxy terminus: closer homology with the mouse protein than previously reported

A. Urquhart

Nucleic Acids Res. 1991 Oct 25; 19(20): 5803. doi: 10.1093/nar/19.20.5803

PMCID:: PMC329017

Summary Page Browse PDF–213K

Select item 10878013.

Different cis-Acting Elements Are Involved in the Regulation of TRP1 and TRP2 Promoter Activities by Cyclic AMP: Pivotal Role of M Boxes (GTCATGTGCT) and of Microphthalmia

Corine Bertolotto, Roser Buscà, Patricia Abbe, Karine Bille, Edith Aberdam, Jean-Paul Ortonne, Robert Ballotti

Mol Cell Biol. 1998 Feb; 18(2): 694–702. doi: 10.1128/mcb.18.2.694

PMCID:: PMC108780

Abstract Article PDF–484K

Select item 677799214.

The TYRP1-mediated protection of human tyrosinase activity does not involve stable interactions of tyrosinase domains.

Monika B. Dolinska, Paul T. Wingfield, Kenneth L. Young, II, Yuri V. Sergeev

Pigment Cell Melanoma Res. Author manuscript; available in PMC 2020 Nov 1.

Published in final edited form as: Pigment Cell Melanoma Res. 2019 Nov; 32(6): 753–765. Published online 2019 Jun 3. doi: 10.1111/pcmr.12791

PMCID:: PMC6777992

Abstract Article PDF–2.2M

Select item 464753215.

SNPs at miR-155 binding sites of TYRP1 explain discrepancy between mRNA and protein and refine TYRP1 prognostic value in melanoma

P El Hajj, D Gilot, M Migault, A Theunis, L C van Kempen, F Salés, H Fayyad-Kazan, B Badran, D Larsimont, A Awada, L Bachelot, M-D Galibert, G Ghanem, F Journe

Br J Cancer. 2015 Jun 30; 113(1): 91–98. Published online 2015 Jun 11. doi: 10.1038/bjc.2015.194

PMCID:: PMC4647532

Abstract Article PDF–1.4M

Select item 426841916.

MELANOCYTIC GALECTIN-3 IS ASSOCIATED WITH TYROSINASE RELATED PROTEIN-1 AND PIGMENT BIOSYNTHESIS

Allison Chalupa, Amy Koshoffer, Emily Galan, Lan Yu, Fu-Tong Liu, Raymond E. Boissy

J Invest Dermatol. Author manuscript; available in PMC 2015 Jul 1.

Published in final edited form as: J Invest Dermatol. 2015 Jan; 135(1): 202–211. Published online 2014 Jul 23. doi: 10.1038/jid.2014.315

PMCID:: PMC4268419

Abstract Article PDF–1.9M

Select item 390388217.

p53 Regulation by TRP2 Is Not Pervasive in Melanoma

Roland Houben, Corinna P. Schmid, Melissa Maier, Marion Wobser, Stephanie Motschenbacher, Jürgen C. Becker, Claudia S. Vetter-Kauczok, Gerhard Weyandt, Sonja Hesbacher, Sebastian Haferkamp

PLoS One. 2014; 9(1): e87440. Published online 2014 Jan 27. doi: 10.1371/journal.pone.0087440

PMCID:: PMC3903882

Abstract Article PDF–588K

Select item 348118218.

Melanesians blond hair is caused by an amino acid change in TYRP1

Eimear E Kenny, Nicholas J Timpson, Martin Sikora, Muh-Ching Yee, Andres Moreno Estrada, Celeste Eng, Scott Huntsman, Esteban González Burchard, Mark Stoneking, Carlos D Bustamante, Sean M Myles

Science. Author manuscript; available in PMC 2012 Oct 26.

Published in final edited form as: Science. 2012 May 4; 336(6081): 554. doi: 10.1126/science.1217849

PMCID:: PMC3481182

Abstract Article PDF–1.7M

Select item 229270019.

Complex signatures of selection for the melanogenic loci TYR, TYRP1 and DCT in humans

Santos Alonso, Neskuts Izagirre, Isabel Smith-Zubiaga, Jesús Gardeazabal, José Luís Díaz-Ramón, José Luís Díaz-Pérez, Diana Zelenika, María Dolores Boyano, Nico Smit, Concepción de la Rúa

BMC Evol Biol. 2008; 8: 74. Published online 2008 Feb 29. doi: 10.1186/1471-2148-8-74

PMCID:: PMC2292700

Abstract Article PDF–511K

Select item 191506920.

Mutation in and lack of expression of tyrosinase-related protein-1 (TRP-1) in melanocytes from an individual with brown oculocutaneous albinism: a new subtype of albinism classified as "OCA3".

R. E. Boissy, H. Zhao, W. S. Oetting, L. M. Austin, S. C. Wildenberg, Y. L. Boissy, Y. Zhao, R. A. Sturm, V. J. Hearing, R. A. King, J. J. Nordlund

Am J Hum Genet. 1996 Jun; 58(6): 1145–1156.

PMCID:: PMC1915069

Summary Page Browse PDF–3.5M

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Hdac2 histone deacetylase 2 [Mus musculus]
Hdac2 histone deacetylase 2 [Mus musculus]
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