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Select item 108358441.

TRIM25 promotes glioblastoma cell growth and invasion via regulation of the PRMT1/c-MYC pathway by targeting the splicing factor NONO

Yike Chen, Xiaohui Xu, Kaikai Ding, Tianchi Tang, Feng Cai, Haocheng Zhang, Zihang Chen, Yangjian Qi, Zaixiang Fu, Ganggui Zhu, Zhangqi Dou, Jinfang Xu, Gao Chen, Qun Wu, Jianxiong Ji, Jianmin Zhang

J Exp Clin Cancer Res. 2024; 43: 39. Published online 2024 Feb 2. doi: 10.1186/s13046-024-02964-6

PMCID:: PMC10835844

Abstract Article PDF–8.5M

Select item 107467002.

TRIM25 dictates selective miRNA loading into extracellular vesicles during inflammation

Kayla E. King, Priyanka Ghosh, Ann L. Wozniak

Sci Rep. 2023; 13: 22952. Published online 2023 Dec 22. doi: 10.1038/s41598-023-50336-5

PMCID:: PMC10746700

Abstract Article PDF–3.4M

Select item 104549323.

TRIM25 Suppresses Rabies Virus Fixed HEP-Flury Strain Production by Activating RIG-1-Mediated Type I Interferons

Boyue Zhang, Ting Cai, Hongling He, Xuezhe Huang, Yongwen Luo, Shile Huang, Jun Luo, Xiaofeng Guo

Genes (Basel) 2023 Aug; 14(8): 1555. Published online 2023 Jul 29. doi: 10.3390/genes14081555

PMCID:: PMC10454932

Abstract Article PDF–4.0M

Select item 95541704.

Tripartite motif-containing 25 facilitates immunosuppression and inhibits apoptosis of glioma via activating NF-κB

Mao-xu Ge, Yi-kang Shi, Dong Liu

Exp Biol Med (Maywood) 2022 Sep; 247(17): 1529–1541. Published online 2022 Jun 20. doi: 10.1177/15353702221099460

PMCID:: PMC9554170

Abstract Article PDF–2.7M

Select item 94211285.

Human metapneumovirus M2-2 protein inhibits RIG-I signaling by preventing TRIM25-mediated RIG-I ubiquitination

Yukie Tanaka, Naoko Morita, Yoshinori Kitagawa, Bin Gotoh, Takayuki Komatsu

Front Immunol. 2022; 13: 970750. Published online 2022 Aug 15. doi: 10.3389/fimmu.2022.970750

PMCID:: PMC9421128

Abstract Article PDF–9.2M

Select item 92626046.

TRIM25 inhibits influenza A virus infection, destabilizes viral mRNA, but is redundant for activating the RIG-I pathway

Nila Roy Choudhury, Ivan Trus, Gregory Heikel, Magdalena Wolczyk, Jacek Szymanski, Agnieszka Bolembach, Rute Maria Dos Santos Pinto, Nikki Smith, Maryia Trubitsyna, Eleanor Gaunt, Paul Digard, Gracjan Michlewski

Nucleic Acids Res. 2022 Jul 8; 50(12): 7097–7114. Published online 2022 Jun 23. doi: 10.1093/nar/gkac512

PMCID:: PMC9262604

Abstract Article PDF–2.9M

Select item 73071787.

Middle East Respiratory Syndrome Coronavirus Nucleocapsid Protein Suppresses Type I and Type III Interferon Induction by Targeting RIG-I Signaling

Chi-You Chang, Helene Minyi Liu, Ming-Fu Chang, Shin C. Chang

J Virol. 2020 Jul; 94(13): e00099-20. Prepublished online 2020 Apr 15. Published online 2020 Jun 16. doi: 10.1128/JVI.00099-20

PMCID:: PMC7307178

Abstract Article PDF–3.2M

Select item 69691538.

TRIM25 promotes the cell survival and growth of hepatocellular carcinoma through targeting Keap1-Nrf2 pathway

Yanfeng Liu, Shishi Tao, Lijuan Liao, Yang Li, Hongchang Li, Zhihuan Li, Lilong Lin, Xiaochun Wan, Xiaolu Yang, Liang Chen

Nat Commun. 2020; 11: 348. Published online 2020 Jan 17. doi: 10.1038/s41467-019-14190-2

PMCID:: PMC6969153

Abstract Article PDF–2.9M

Select item 61892179.

The E3 ubiquitin ligase TRIM25 regulates adipocyte differentiation via proteasome-mediated degradation of PPARγ

Jae Min Lee, Sun Sil Choi, Yo Han Lee, Keon Woo Khim, Sora Yoon, Byung-gyu Kim, Dougu Nam, Pann-Ghill Suh, Kyungjae Myung, Jang Hyun Choi

Exp Mol Med. 2018 Oct; 50(10): 135. Published online 2018 Oct 15. doi: 10.1038/s12276-018-0162-6

PMCID:: PMC6189217

Abstract Article PDF–1.9M

Select item 594077210.

Molecular mechanism of influenza A NS1-mediated TRIM25 recognition and inhibition

Marios G. Koliopoulos, Mathilde Lethier, Annemarthe G. van der Veen, Kevin Haubrich, Janosch Hennig, Eva Kowalinski, Rebecca V. Stevens, Stephen R. Martin, Caetano Reis e Sousa, Stephen Cusack, Katrin Rittinger

Nat Commun. 2018; 9: 1820. Published online 2018 May 8. doi: 10.1038/s41467-018-04214-8

PMCID:: PMC5940772

Abstract Article PDF–2.6M

Select item 584361311.

Type I IFN augments IL-27-dependent TRIM25 expression to inhibit HBV replication

Guangyun Tan, Qingfei Xiao, Hongxiao Song, Feng Ma, Fengchao Xu, Di Peng, Na Li, Xiaosong Wang, Junqi Niu, Pujun Gao, F Xiao-Feng Qin, Genhong Cheng

Cell Mol Immunol. 2018 Mar; 15(3): 272–281. Published online 2017 Feb 13. doi: 10.1038/cmi.2016.67

PMCID:: PMC5843613

Abstract Article PDF–2.3M

Select item 561491912.

TRIM25 in the Regulation of the Antiviral Innate Immunity

María Martín-Vicente, Luz M. Medrano, Salvador Resino, Adolfo García-Sastre, Isidoro Martínez

Front Immunol. 2017; 8: 1187. Published online 2017 Sep 22. doi: 10.3389/fimmu.2017.01187

PMCID:: PMC5614919

Abstract Article PDF–1.9M

Select item 482400413.

Dengue subgenomic RNA binds TRIM25 to inhibit interferon expression for epidemiological fitness

Gayathri Manokaran, Esteban Finol, Chunling Wang, Jayantha Gunaratne, Justin Bahl, Eugenia Z. Ong, Hwee Cheng Tan, October M. Sessions, Alex M. Ward, Duane J. Gubler, Eva Harris, Mariano A. Garcia-Blanco, Eng Eong Ooi

Science. Author manuscript; available in PMC 2016 Apr 7.

Published in final edited form as: Science. 2015 Oct 9; 350(6257): 217–221. Published online 2015 Jul 2. doi: 10.1126/science.aab3369

PMCID:: PMC4824004

Abstract Article PDF–1.2M

Select item 393286414.

The tripartite motif coiled-coil is an elongated antiparallel hairpin dimer

Jacint G. Sanchez, Katarzyna Okreglicka, Viswanathan Chandrasekaran, Jordan M. Welker, Wesley I. Sundquist, Owen Pornillos

Proc Natl Acad Sci U S A. 2014 Feb 18; 111(7): 2494–2499. Published online 2014 Feb 3. doi: 10.1073/pnas.1318962111

PMCID:: PMC3932864

Abstract Article PDF–1.3M

Select item 1091250915.

Suppression of ITPKB degradation by Trim25 confers TMZ resistance in glioblastoma through ROS homeostasis

Yuanliang Yan, Shangjun Zhou, Xi Chen, Qiaoli Yi, Songshan Feng, Zijin Zhao, Yuanhong Liu, Qiuju Liang, Zhijie Xu, Zhi Li, Lunquan Sun

Signal Transduct Target Ther. 2024; 9: 58. Published online 2024 Mar 4. doi: 10.1038/s41392-024-01763-x

PMCID:: PMC10912509

Abstract Article PDF–5.9M

Select item 950487516.

Hazara Orthonairovirus Nucleoprotein Antagonizes Type I Interferon Production by Inhibition of RIG-I Ubiquitination

Keisuke Ohta, Naoki Saka, Machiko Nishio

Viruses. 2022 Sep; 14(9): 1965. Published online 2022 Sep 4. doi: 10.3390/v14091965

PMCID:: PMC9504875

Abstract Article PDF–2.4M

Select item 935488917.

IFN-I inducible miR-3614-5p targets ADAR1 isoforms and fine tunes innate immune activation

Françoise Vuillier, Zhi Li, Iain Black, Melania Cruciani, Erminia Rubino, Frédérique Michel, Sandra Pellegrini

Front Immunol. 2022; 13: 939907. Published online 2022 Jul 22. doi: 10.3389/fimmu.2022.939907

PMCID:: PMC9354889

Abstract Article PDF–2.4M

Select item 925356718.

The Role of ZAP and TRIM25 RNA Binding in Restricting Viral Translation

Emily Yang, LeAnn P. Nguyen, Carlyn A. Wisherop, Ryan L. Kan, Melody M.H. Li

Front Cell Infect Microbiol. 2022; 12: 886929. Published online 2022 Jun 21. doi: 10.3389/fcimb.2022.886929

PMCID:: PMC9253567

Abstract Article PDF–6.0M

Select item 859180119.

CircRNA-DOPEY2 enhances the chemosensitivity of esophageal cancer cells by inhibiting CPEB4-mediated Mcl-1 translation

Zhenchuan Liu, Shaorui Gu, Kaiqin Wu, Lei Li, Chenglai Dong, Wenli Wang, Yongxin Zhou

J Exp Clin Cancer Res. 2021; 40: 361. Published online 2021 Nov 15. doi: 10.1186/s13046-021-02149-5

Correction in:: J Exp Clin Cancer Res. 2022; 41: 61.

PMCID:: PMC8591801

Abstract Article PDF–11M

Select item 831611020.

SARS-CoV-2 Nonstructural Protein 1 Inhibits the Interferon Response by Causing Depletion of Key Host Signaling Factors

Anil Kumar, Ray Ishida, Tania Strilets, Jamie Cole, Joaquin Lopez-Orozco, Nawell Fayad, Alberto Felix-Lopez, Mohamed Elaish, Danyel Evseev, Katharine E. Magor, Lara K. Mahal, Les P. Nagata, David H. Evans, Tom C. Hobman

J Virol. 2021 Jul; 95(13): e00266-21. Prepublished online 2021 Apr 20. Published online 2021 Jun 10. doi: 10.1128/JVI.00266-21