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Select item 98935141.

Novel mechanosensory role for acid sensing ion channel subtype 1a in evoking the exercise pressor reflex in rats with heart failure

Alec L. E. Butenas, Korynne S. Rollins, Shannon K. Parr, Stephen T. Hammond, Carl J. Ade, K. Sue Hageman, Timothy I. Musch, Steven W. Copp

J Physiol. Author manuscript; available in PMC 2023 May 1.

Published in final edited form as: J Physiol. 2022 May; 600(9): 2105–2125. Published online 2022 Apr 13. doi: 10.1113/JP282923

PMCID:: PMC9893514

Abstract Article PDF–2.1M

Select item 97191532.

Estrogen antagonizes ASIC1a-induced chondrocyte mitochondrial stress in rheumatoid arthritis

Zhuoyan Zai, Yayun Xu, Xuewen Qian, Zihan Li, Ziyao Ou, Tao Zhang, Longfei Wang, Yian Ling, Xiaoqing Peng, Yihao Zhang, Feihu Chen

J Transl Med. 2022; 20: 561. Published online 2022 Dec 3. doi: 10.1186/s12967-022-03781-1

PMCID:: PMC9719153

Abstract Article PDF–10M

Select item 90923523.

Overexpression of ASIC1A in the nucleus accumbens of rats potentiates cocaine-seeking behavior

Andrea L. Gutman, Caitlin V. Cosme, Maria F. Noterman, Wensday R. Worth, John A. Wemmie, Ryan T. LaLumiere

Addict Biol. Author manuscript; available in PMC 2022 May 11.

Published in final edited form as: Addict Biol. 2020 Mar; 25(2): e12690. Published online 2018 Nov 6. doi: 10.1111/adb.12690

PMCID:: PMC9092352

Abstract Article PDF–500K

Select item 74744444.

ASIC1a does not play a role in evoking the metabolic component of the exercise pressor reflex in a rat model of peripheral artery disease

Guillaume P. Ducrocq, Joyce S. Kim, Juan A. Estrada, Marc P. Kaufman

Am J Physiol Heart Circ Physiol. 2020 Jul 1; 319(1): H171–H182. Published online 2020 Jun 5. doi: 10.1152/ajpheart.00257.2020

PMCID:: PMC7474444

Abstract Article

Select item 73774595.

Coupling of store-operated calcium entry to vasoconstriction is acid-sensing ion channel 1a dependent in pulmonary but not mesenteric arteries

Selina M. Garcia, Lindsay M. Herbert, Benjimen R. Walker, Thomas C. Resta, Nikki L. Jernigan

PLoS One. 2020; 15(7): e0236288. Published online 2020 Jul 23. doi: 10.1371/journal.pone.0236288

PMCID:: PMC7377459

Abstract Article PDF–2.5M

Select item 72629436.

ASIC1a inhibits cell pyroptosis induced by acid‐induced activation of rat hepatic stellate cells

Jun Li, Lingjin Kong, Huiping Huang, Shaohua Luan, Rui Jin, Fanrong Wu

FEBS Open Bio. 2020 Jun; 10(6): 1044–1055. Published online 2020 Apr 28. doi: 10.1002/2211-5463.12850

PMCID:: PMC7262943

Abstract Article PDF–9.5M

Select item 69858067.

ASIC1a plays a key role in evoking the metabolic component of the exercise pressor reflex in rats

Guillaume P. Ducrocq, Joyce S. Kim, Juan A. Estrada, Marc P. Kaufman

Am J Physiol Heart Circ Physiol. 2020 Jan 1; 318(1): H78–H89. Published online 2019 Nov 1. doi: 10.1152/ajpheart.00565.2019

PMCID:: PMC6985806

Abstract Article

Select item 66752658.

Silencing Acid-Sensing Ion Channel 1a Alters Cone-Mediated Retinal Function

Mohammed Ettaiche, Emmanuel Deval, Marc Cougnon, Michel Lazdunski, Nicolas Voilley

J Neurosci. 2006 May 24; 26(21): 5800–5809. doi: 10.1523/JNEUROSCI.0344-06.2006

PMCID:: PMC6675265

Abstract Article PDF–2.8M

Select item 65334929.

PI3‐kinase/Akt pathway‐regulated membrane transportation of acid‐sensing ion channel 1a/Calcium ion influx/endoplasmic reticulum stress activation on PDGF‐induced HSC Activation

Longquan Zuo, Yueqin Zhu, Lili Hu, Yanyi Liu, Yinghong Wang, Yamin Hu, Huan Wang, Xuesheng Pan, Kuayue Li, Na Du, Yan Huang

J Cell Mol Med. 2019 Jun; 23(6): 3940–3950. Published online 2019 Apr 2. doi: 10.1111/jcmm.14275

PMCID:: PMC6533492

Abstract Article PDF–1.5M

Select item 641415410.

Inhibition of acid-sensing ion channel 1a attenuates acid-induced activation of autophagy via a calcium signaling pathway in articular chondrocytes

Wen-Fan Gao, Ya-Yun Xu, Jin-Fang Ge, Fei-Hu Chen

Int J Mol Med. 2019 Apr; 43(4): 1778–1788. Published online 2019 Jan 31. doi: 10.3892/ijmm.2019.4085

PMCID:: PMC6414154

Abstract Article PDF–1.0M

Select item 595248711.

ASIC1a contributes to the symptom of pain in a rat model of chronic prostatitis

Song Fan, Zong-Yao Hao, Li Zhang, Jun Zhou, Yi-Fei Zhang, Shen Tai, Xian-Sheng Zhang, Chao-Zhao Liang

Asian J Androl. 2018 May-Jun; 20(3): 300–305. Published online 2017 Dec 8. doi: 10.4103/aja.aja_55_17

PMCID:: PMC5952487

Abstract Article PDF–2.1M

Select item 566680712.

ASIC1a Promotes Acid-Induced Autophagy in Rat Articular Chondrocytes through the AMPK/FoxO3a Pathway

Beibei Dai, Fei Zhu, Yong Chen, Renpeng Zhou, Zhisen Wang, Yaya Xie, Xiaoshan Wu, Shengqin Zu, Ge Li, Jinfang Ge, Feihu Chen

Int J Mol Sci. 2017 Oct; 18(10): 2125. Published online 2017 Oct 11. doi: 10.3390/ijms18102125

PMCID:: PMC5666807

Abstract Article PDF–4.9M

Select item 534079413.

Acid-Sensing Ion Channel 1a in the amygdala is involved in pain and anxiety-related behaviours associated with arthritis

Youssef Aissouni, Abderrahim El Guerrab, Al Mahdy Hamieh, Jérémy Ferrier, Maryse Chalus, Diane Lemaire, Stéphanie Grégoire, Monique Etienne, Alain Eschalier, Denis Ardid, Eric Lingueglia, Fabien Marchand

Sci Rep. 2017; 7: 43617. Published online 2017 Mar 2. doi: 10.1038/srep43617

PMCID:: PMC5340794

Abstract Article PDF–1.3M

Select item 474273214.

Mambalgin-1 Pain-relieving Peptide, Stepwise Solid-phase Synthesis, Crystal Structure, and Functional Domain for Acid-sensing Ion Channel 1a Inhibition

Gilles Mourier, Miguel Salinas, Pascal Kessler, Enrico A. Stura, Mathieu Leblanc, Livia Tepshi, Thomas Besson, Sylvie Diochot, Anne Baron, Dominique Douguet, Eric Lingueglia, Denis Servent

J Biol Chem. 2016 Feb 5; 291(6): 2616–2629. Published online 2015 Dec 17. doi: 10.1074/jbc.M115.702373

PMCID:: PMC4742732

Abstract Article PDF–3.2M

Select item 468047115.

Effect of activation of the Ca²⁺-permeable acid-sensing ion channel 1a on focal cerebral ischemia in diabetic rats

Jie Wang, Chun-Yan Wen, Cui-Cui Cui, Ying Xing

Int J Clin Exp Pathol. 2015; 8(10): 13255–13260. Published online 2015 Oct 1.

PMCID:: PMC4680471

Abstract Article PDF–712K

Select item 467974916.

Involvement of acid-sensing ion channel 1a in matrix metabolism of endplate chondrocytes under extracellular acidic conditions through NF-κB transcriptional activity

Feng-Lai Yuan, Ming-Dong Zhao, Dong-Lin Jiang, Cheng Jin, Hai-Fei Liu, Ming-Hui Xu, Wei Hu, Xia Li

Cell Stress Chaperones. 2016 Jan; 21(1): 97–104. Published online 2015 Sep 18. doi: 10.1007/s12192-015-0643-7

PMCID:: PMC4679749

Abstract Article PDF–1.2M

Select item 462198017.

Molecular dynamics and functional studies define a hot spot of crystal contacts essential for PcTx1 inhibition of acid‐sensing ion channel 1a

Natalie J Saez, Evelyne Deplazes, Ben Cristofori‐Armstrong, Irène R Chassagnon, Xiaozhen Lin, Mehdi Mobli, Alan E Mark, Lachlan D Rash, Glenn F King

Br J Pharmacol. 2015 Oct; 172(20): 4985–4995. Published online 2015 Sep 22. doi: 10.1111/bph.13267

PMCID:: PMC4621980

Abstract Article PDF–1.8M

Select item 403634518.

Binding Site and Inhibitory Mechanism of the Mambalgin-2 Pain-relieving Peptide on Acid-sensing Ion Channel 1a

Miguel Salinas, Thomas Besson, Quentin Delettre, Sylvie Diochot, Sonia Boulakirba, Dominique Douguet, Eric Lingueglia

J Biol Chem. 2014 May 9; 289(19): 13363–13373. Published online 2014 Apr 2. doi: 10.1074/jbc.M114.561076

PMCID:: PMC4036345

Abstract Article PDF–3.5M

Select item 393507919.

ASIC1a Activation Enhances Inhibition in the Basolateral Amygdala and Reduces Anxiety

Volodymyr I. Pidoplichko, Vassiliki Aroniadou-Anderjaska, Eric M. Prager, Taiza H. Figueiredo, Camila P. Almeida-Suhett, Steven L. Miller, Maria F. M. Braga

J Neurosci. 2014 Feb 26; 34(9): 3130–3141. doi: 10.1523/JNEUROSCI.4009-13.2014