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Select item 56616091.

Dysregulation of KRAS signaling in pancreatic cancer is not associated with KRAS mutations and outcome

Radmila Lemstrova, Veronika Brynychova, David J. Hughes, Viktor Hlavac, Pavel Dvorak, Joanne E. Doherty, Helena A. Murray, Martin Crockard, Martin Oliverius, Jan Hlavsa, Eva Honsova, Jan Mazanec, Zdenek Kala, Martin Lovecek, Roman Havlik, Jiri Ehrmann, Ondrej Strouhal, Pavel Soucek, Bohuslav Melichar, Beatrice Mohelnikova-Duchonova

Oncol Lett. 2017 Nov; 14(5): 5980–5988. Published online 2017 Sep 14. doi: 10.3892/ol.2017.6946

PMCID:: PMC5661609

Abstract Article PDF–1.1M

Select item 4200812.

RalA Activation at Nascent Lamellipodia of Epidermal Growth Factor-stimulated Cos7 Cells and Migrating Madin-Darby Canine Kidney Cells

Akiyuki Takaya, Yusuke Ohba, Kazuo Kurokawa, Michiyuki Matsuda

Mol Biol Cell. 2004 Jun; 15(6): 2549–2557. doi: 10.1091/mbc.E03-11-0857

PMCID:: PMC420081

Abstract Article PDF–546K

Select item 66722883.

RalA and RalB Function as the Critical GTP Sensors for GTP-Dependent Exocytosis

Gang Li, Liping Han, Ting-Chieh Chou, Yoshihito Fujita, Lakshmanan Arunachalam, Ainan Xu, Aaron Wong, Soon-Kwang Chiew, Qi Wan, Li Wang, Shuzo Sugita

J Neurosci. 2007 Jan 3; 27(1): 190–202. doi: 10.1523/JNEUROSCI.2537-06.2007

PMCID:: PMC6672288

Abstract Article PDF–971K

Select item 27668364.

The GTPase RalA Regulates Different Steps of the Secretory Process in Pancreatic β-Cells

Sanda Ljubicic, Paola Bezzi, Nicolas Vitale, Romano Regazzi

PLoS One. 2009; 4(11): e7770. Published online 2009 Nov 5. doi: 10.1371/journal.pone.0007770

PMCID:: PMC2766836

Abstract Article PDF–317K

Select item 44453735.

RAL-REGULATED INTERACTION BETWEEN SEC5 AND PAXILLIN TARGETS EXOCYST TO FOCAL COMPLEXES DURING CELL MIGRATION

Krystle S. Spiczka, Charles Yeaman

J Cell Sci. Author manuscript; available in PMC 2015 May 27.

Published in final edited form as: J Cell Sci. 2008 Sep 1; 121(0 17): 2880–2891. Published online 2008 Aug 12. doi: 10.1242/jcs.031641

PMCID:: PMC4445373

Abstract Article PDF–2.2M

Select item 27305306.

Regulated RalBP1 Binding to RalA and PSD-95 Controls AMPA Receptor Endocytosis and LTD

Kihoon Han, Myoung-Hwan Kim, Daniel Seeburg, Jinsoo Seo, Chiara Verpelli, Seungnam Han, Hye Sun Chung, Jaewon Ko, Hyun Woo Lee, Karam Kim, Won Do Heo, Tobias Meyer, Hyun Kim, Carlo Sala, Se-Young Choi, Morgan Sheng, Eunjoon Kim

PLoS Biol. 2009 Sep; 7(9): e1000187. Published online 2009 Sep 8. doi: 10.1371/journal.pbio.1000187

PMCID:: PMC2730530

Abstract Article PDF–1.6M

Select item 21712847.

Ral GTPases regulate neurite branching through GAP-43 and the exocyst complex

Giovanna Lalli, Alan Hall

J Cell Biol. 2005 Dec 5; 171(5): 857–869. doi: 10.1083/jcb.200507061

PMCID:: PMC2171284

Abstract Article PDF–13M

Select item 28221038.

RalA-Exocyst Complex Regulates Integrin-Dependent Membrane Raft Exocytosis and Growth Signaling

Nagaraj Balasubramanian, Jeremy A. Meier, David W. Scott, Andrés Norambuena, Michael A. White, Martin Alexander Schwartz

Curr Biol. Author manuscript; available in PMC 2011 Jan 12.

Published in final edited form as: Curr Biol. 2010 Jan 12; 20(1): 75. Published online 2009 Dec 10. doi: 10.1016/j.cub.2009.11.016

PMCID:: PMC2822103

Abstract Article PDF–2.8M

Select item 25430549.

Distinct roles of RalA and RalB in the progression of cytokinesis are supported by distinct RalGEFs

Ilaria Cascone, Rasim Selimoglu, Cafer Ozdemir, Elaine Del Nery, Charles Yeaman, Michael White, Jacques Camonis

EMBO J. 2008 Sep 17; 27(18): 2375–2387. Published online 2008 Aug 28. doi: 10.1038/emboj.2008.166

PMCID:: PMC2543054

Abstract Article PDF–2.5M

Select item 216915910.

Geranylgeranyltransferase I Inhibitors Target RalB To Inhibit Anchorage-Dependent Growth and Induce Apoptosis and RalA To Inhibit Anchorage-Independent Growth

Samuel C. Falsetti, De-an Wang, Hairuo Peng, Dora Carrico, Adrienne D. Cox, Channing J. Der, Andrew D. Hamilton, Saïd M. Sebti

Mol Cell Biol. 2007 Nov; 27(22): 8003–8014. Published online 2007 Sep 17. doi: 10.1128/MCB.00057-07

PMCID:: PMC2169159

Abstract Article PDF–617K

Select item 115089311.

Exo84 and Sec5 are competitive regulatory Sec6/8 effectors to the RalA GTPase

Rongsheng Jin, Jagath R Junutula, Hugo T Matern, Karen E Ervin, Richard H Scheller, Axel T Brunger

EMBO J. 2005 Jun 15; 24(12): 2064–2074. Published online 2005 May 26. doi: 10.1038/sj.emboj.7600699

PMCID:: PMC1150893

Abstract Article PDF–686K

Select item 23069812.

Identification and characterization of Ral-binding protein 1, a potential downstream target of Ral GTPases.

S B Cantor, T Urano, L A Feig

Mol Cell Biol. 1995 Aug; 15(8): 4578–4584. doi: 10.1128/mcb.15.8.4578

PMCID:: PMC230698

Summary PDF–722K

Select item 2674713.

The small GTPase RalA targets filamin to induce filopodia

Yasutaka Ohta, Nobuchika Suzuki, Shun Nakamura, John H. Hartwig, Thomas P. Stossel

Proc Natl Acad Sci U S A. 1999 Mar 2; 96(5): 2122–2128. doi: 10.1073/pnas.96.5.2122

PMCID:: PMC26747

Abstract Article PDF–466K

Select item 54491014.

RalA interacts with ZONAB in a cell density-dependent manner and regulates its transcriptional activity

Paul Frankel, Ami Aronheim, Emma Kavanagh, Maria S Balda, Karl Matter, Tom D Bunney, Christopher J Marshall

EMBO J. 2005 Jan 12; 24(1): 54–62. Published online 2004 Dec 9. doi: 10.1038/sj.emboj.7600497

PMCID:: PMC544910

Abstract Article PDF–361K

Select item 301697215.

A Ral GAP complex links PI 3-kinase/Akt signaling to RalA activation in insulin action

Xiao-Wei Chen, Dara Leto, Tingting Xiong, Genggeng Yu, Alan Cheng, Stuart Decker, Alan R. Saltiel

Mol Biol Cell. 2011 Jan 1; 22(1): 141–152. doi: 10.1091/mbc.E10-08-0665

PMCID:: PMC3016972

Abstract Article PDF–7.7M

Select item 267610116.

Proteolipid Protein Is Required for Transport of Sirtuin 2 into CNS Myelin

Hauke B. Werner, Katja Kuhlmann, Siming Shen, Marina Uecker, Anke Schardt, Kalina Dimova, Foteini Orfaniotou, Ajit Dhaunchak, Bastian G. Brinkmann, Wiebke Möbius, Lenny Guarente, Patrizia Casaccia-Bonnefil, Olaf Jahn, Klaus-Armin Nave

J Neurosci. 2007 Jul 18; 27(29): 7717–7730. doi: 10.1523/JNEUROSCI.1254-07.2007