PMC Links for Gene (Select 83725) - PMC

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Items: 16

Select item 98925581.

Endoplasmic reticulum stress inhibition ameliorated WFS1 expression alterations and reduced pancreatic islets’ insulin secretion induced by high-fat diet in rats

Fateme Binayi, Javad Fahanik-Babaei, Mina Salimi, Farzaneh Eskandari, Mohammad Sahraei, Ali Ghorbani Ranjbary, Rasoul Ghasemi, Mehdi Hedayati, Fariba Khodagholi, Afsaneh Eliassi, Homeira Zardooz

Sci Rep. 2023; 13: 1860. Published online 2023 Feb 1. doi: 10.1038/s41598-023-28329-1

PMCID:: PMC9892558

Abstract Article PDF–5.1M

Select item 73822782.

Calpain inhibitor and ibudilast rescue β cell functions in a cellular model of Wolfram syndrome

Lien D. Nguyen, Tom T. Fischer, Damien Abreu, Alfredo Arroyo, Fumihiko Urano, Barbara E. Ehrlich

Proc Natl Acad Sci U S A. 2020 Jul 21; 117(29): 17389–17398. Published online 2020 Jul 6. doi: 10.1073/pnas.2007136117

PMCID:: PMC7382278

Abstract Article PDF–1.7M

Select item 60338613.

Preventive treatment with liraglutide protects against development of glucose intolerance in a rat model of Wolfram syndrome

Maarja Toots, Kadri Seppa, Toomas Jagomäe, Tuuliki Koppel, Maia Pallase, Indrek Heinla, Anton Terasmaa, Mario Plaas, Eero Vasar

Sci Rep. 2018; 8: 10183. Published online 2018 Jul 5. doi: 10.1038/s41598-018-28314-z

PMCID:: PMC6033861

Abstract Article PDF–2.0M

Select item 55792614.

Wfs1- deficient rats develop primary symptoms of Wolfram syndrome: insulin-dependent diabetes, optic nerve atrophy and medullary degeneration

Mario Plaas, Kadri Seppa, Riin Reimets, Toomas Jagomäe, Maarja Toots, Tuuliki Koppel, Tuuli Vallisoo, Mait Nigul, Indrek Heinla, Riho Meier, Allen Kaasik, Andres Piirsoo, Miriam A. Hickey, Anton Terasmaa, Eero Vasar

Sci Rep. 2017; 7: 10220. Published online 2017 Aug 31. doi: 10.1038/s41598-017-09392-x

PMCID:: PMC5579261

Abstract Article PDF–7.9M

Select item 27780985.

Expression and localization of Wolfram syndrome 1 gene in the developing rat pancreas

Rong Xu, Biao Xia, Jie Geng, Jing Shi, Hui Shi, Li Yuan, Wei De

World J Gastroenterol. 2009 Nov 21; 15(43): 5425–5431. Published online 2009 Nov 21. doi: 10.3748/wjg.15.5425

PMCID:: PMC2778098

Abstract Article PDF–2.4M

Select item 61988166.

Mutations in the Wolfram syndrome 1 gene (WFS1) are a common cause of low frequency sensorineural hearing loss

Irina N. Bespalova, Guy Van Camp, Steven J.H. Bom, David J. Brown, Kim Cryns, Andrew T. DeWan, Ayse E. Erson, Kris Flothmann, Henricus P.M. Kunst, Purnima Kurnool, Theru A. Sivakumaran, Cor W.R.J. Cremers, Suzanne M. Leal, Margit Burmeister, Marci M. Lesperance

Hum Mol Genet. Author manuscript; available in PMC 2018 Oct 23.

Published in final edited form as: Hum Mol Genet. 2001 Oct 15; 10(22): 2501–2508. doi: 10.1093/hmg/10.22.2501

PMCID:: PMC6198816

Abstract Article PDF–1.1M

Select item 31435437.

A WFS1 Haplotype Consisting of the Minor Alleles of rs752854, rs10010131, and rs734312 Shows a Protective Role Against Type 2 Diabetes in Russian Patients

Dimitry A Chistiakov, Dmitry S. Khodyrev, Svetlana A. Smetanina, Larisa N. Bel'chikova, Lyudmila A. Suplotova, Valery V. Nosikov

Rev Diabet Stud. 2010 Winter; 7(4): 285–292. Published online 2011 Feb 10. doi: 10.1900/RDS.2010.7.285

PMCID:: PMC3143543

Abstract Article PDF–138K

Select item 31003668.

Identification of p.A684V missense mutation in the WFS1 gene as a frequent cause of autosomal dominant optic atrophy and hearing impairment

Nanna D. Rendtorff, Marianne Lodahl, Houda Boulahbel, Ida R. Johansen, Arti Pandya, Katherine O. Welch, Virginia W. Norris, Kathleen S. Arnos, Maria Bitner-Glindzicz, Sarah B. Emery, Marilyn B. Mets, Toril Fagerheim, Kristina Eriksson, Lars Hansen, Helene Bruhn, Claes Möller, Sture Lindholm, Stefan Ensgård, Marci M. Lesperance, Lisbeth Tranebjærg

Am J Med Genet A. Author manuscript; available in PMC 2012 Jun 1.

Published in final edited form as: Am J Med Genet A. 2011 Jun; 155(6): 1298–1313. Published online 2011 Apr 28. doi: 10.1002/ajmg.a.33970

PMCID:: PMC3100366

Abstract Article PDF–939K

Select item 26701959.

Replication of the association between variants in the WFS1 gene and risk of type 2 diabetes in European populations

P.W. Franks, O. Rolandsson, S.L. Debenham, K.A. Fawcett, F. Payne, C. Dina, P. Froguel, K.L. Mohlke, C. Willer, T. Olsson, N.J. Wareham, G. Hallmans, I Barroso, M.S. Sandhu

Diabetologia. Author manuscript; available in PMC 2009 Apr 17.

Published in final edited form as: Diabetologia. 2008 Mar; 51(3): 458–463. Published online 2007 Nov 27. doi: 10.1007/s00125-007-0887-6

Correction in:: volume 51 on page 523

PMCID:: PMC2670195

Abstract Article PDF–655K

Select item 248395510.

Testing of diabetes-associated WFS1 polymorphisms in the Diabetes Prevention Program

J. C. Florez, K. A. Jablonski, J. McAteer, M. S. Sandhu, N. J. Wareham, I. Barroso, P. W. Franks, D. Altshuler, W. C. Knowler, for the Diabetes Prevention Program Research Group

Diabetologia. Author manuscript; available in PMC 2008 Jul 25.

Published in final edited form as: Diabetologia. 2008 Mar; 51(3): 451–457. Published online 2007 Dec 4. doi: 10.1007/s00125-007-0891-x

PMCID:: PMC2483955

Abstract Article PDF–300K

Select item 862180111.

The Expression of RAAS Key Receptors, Agtr2 and Bdkrb1, Is Downregulated at an Early Stage in a Rat Model of Wolfram Syndrome

Marite Punapart, Kadri Seppa, Toomas Jagomäe, Mailis Liiv, Riin Reimets, Silvia Kirillov, Allen Kaasik, Lieve Moons, Lies De Groef, Anton Terasmaa, Eero Vasar, Mario Plaas

Genes (Basel) 2021 Nov; 12(11): 1717. Published online 2021 Oct 28. doi: 10.3390/genes12111717

PMCID:: PMC8621801

Abstract Article PDF–2.6M

Select item 556286212.

CDKAL1 rs7756992 is associated with diabetic retinopathy in a Chinese population with type 2 diabetes

Danfeng Peng, Jie Wang, Rong Zhang, Feng Jiang, Claudia H. T. Tam, Guozhi Jiang, Tao Wang, Miao Chen, Jing Yan, Shiyun Wang, Dandan Yan, Zhen He, Ronald C. W. Ma, Yuqian Bao, Cheng Hu, Weiping Jia

Sci Rep. 2017; 7: 8812. Published online 2017 Aug 18. doi: 10.1038/s41598-017-09010-w

PMCID:: PMC5562862

Abstract Article PDF–1.0M

Select item 610120813.

Sodium-potassium ATPase beta 1 subunit is a molecular partner of Wolframin, an endoplasmic reticulum (ER) protein involved in ER stress

Malgorzata Zatyka, Christopher Ricketts, Gabriela da Silva Xavier, Jayne A. Minton, Sarah Fenton, Sabine Hofmann-Thiel, Guy A. Rutter, Timothy G. Barrett

Hum Mol Genet. Author manuscript; available in PMC 2018 Aug 20.

Published in final edited form as: Hum Mol Genet. 2008 Jan 15; 17(2): 190–200. Published online 2007 Oct 18. doi: 10.1093/hmg/ddm296

PMCID:: PMC6101208

Abstract Article PDF–1.4M

Select item 282794814.

Wolfram syndrome 1 gene negatively regulates ER stress signaling in rodent and human cells

Sonya G. Fonseca, Shinsuke Ishigaki, Christine M. Oslowski, Simin Lu, Kathryn L. Lipson, Rajarshi Ghosh, Emiko Hayashi, Hisamitsu Ishihara, Yoshitomo Oka, M. Alan Permutt, Fumihiko Urano

J Clin Invest. 2010 Mar 1; 120(3): 744–755. Published online 2010 Feb 15. doi: 10.1172/JCI39678

PMCID:: PMC2827948

Abstract Article PDF–4.3M

Select item 285429815.

AATF mediates anti-apoptotic effect of the unfolded protein response through transcriptional regulation of AKT1

Shinsuke Ishigaki, Sonya G. Fonseca, Christine M. Oslowski, Agata Jurczyk, Jeffrey R. Shearstone, Lihua J. Zhu, M. Alan Permutt, Dale L. Greiner, Rita Bortell, Fumihiko Urano

Cell Death Differ. Author manuscript; available in PMC 2010 Nov 1.

Published in final edited form as: Cell Death Differ. 2010 May; 17(5): 774–786. Published online 2009 Nov 13. doi: 10.1038/cdd.2009.175