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Items: 1 to 20 of 180

1.
CUL4B mutations impair human cortical neurogenesis through PP2A-dependent inhibition of AKT and ERK
Yanyan Ma, Xiaolin Liu, Min Zhou, Wenjie Sun, Baichun Jiang, Qiao Liu, Molin Wang, Yongxin Zou, Qiji Liu, Yaoqin Gong, Gongping Sun
Cell Death Dis. 2024 Feb; 15(2): 121. Published online 2024 Feb 8. doi: 10.1038/s41419-024-06501-3
PMCID:
PMC10853546
ArticlePDF–9.0M
2.
The CUL4B‐based E3 ubiquitin ligase regulates mitosis and brain development by recruiting phospho‐specific DCAFs
Anna Stier, Samuel Gilberto, Weaam I Mohamed, Lars N Royall, Jonne Helenius, Ivan Mikicic, Tatjana Sajic, Petra Beli, Daniel J Müller, Sebastian Jessberger, Matthias Peter
EMBO J. 2023 Sep; 42(17): e112847. Published online 2023 Jun 27. doi: 10.15252/embj.2022112847
PMCID:
PMC10476281
ArticlePDF–2.6M
3.
Inhibition of MicroRNA miR-101-3p on prostate cancer progression by regulating Cullin 4B (CUL4B) and PI3K/AKT/mTOR signaling pathways
Zhenhua Gu, Zhixin You, Yucheng Yang, Rui Ding, Meili Wang, Jianming Pu, Jian Chen
Bioengineered. 2021; 12(1): 4719–4735. Published online 2021 Aug 1. doi: 10.1080/21655979.2021.1949513
PMCID:
PMC8806765
ArticlePDF–5.9M
4.
Knockdown of CUL4B Suppresses the Proliferation and Invasion in Non-Small Cell Lung Cancer Cells
Xuguang Wang, Zhe Chen
Oncol Res. 2016; 24(4): 271–277. Published online 2016 Aug 10. doi: 10.3727/096504016X14666990347473
PMCID:
PMC7838745
ArticlePDF–5.3M
5.
CUL4B regulates autophagy via JNK signaling in diffuse large B-cell lymphoma
Ying Li, Xiangxiang Zhou, Ya Zhang, Juan Yang, Yangyang Xu, Yi Zhao, Xin Wang
Cell Cycle. 2019; 18(4): 379–394. Published online 2019 Feb 1. doi: 10.1080/15384101.2018.1560718
PMCID:
PMC6422499
ArticlePDF–3.1M
6.
Knockdown of CUL4B inhibits proliferation and promotes apoptosis of colorectal cancer cells through suppressing the Wnt/β-catenin signaling pathway
Baoji Song, Hongjie Zhan, Quan Bian, Jiarui Li
Int J Clin Exp Pathol. 2015; 8(9): 10394–10402. Published online 2015 Sep 1.
PMCID:
PMC4637562
ArticlePDF–884K
7.
Donor Splice-Site Mutation in CUL4B is Likely Cause of X-Linked Intellectual Disability
Eric R. Londin, Jeffrey Adijanto, Nancy Philp, Antonio Novelli, Emilia Vitale, Chiara Perria, Gigliola Serra, Viola Alesi, Saul Surrey, Paolo Fortina
Am J Med Genet A. Author manuscript; available in PMC 2015 Apr 21.
Published in final edited form as: Am J Med Genet A. 2014 Sep; 0(9): 2294–2299. Published online 2014 Jun 4. doi: 10.1002/ajmg.a.36629
PMCID:
PMC4404493
ArticlePDF–679K
8.
Cul4B regulates neural progenitor cell growth
Helio C Liu, Grigori Enikolopov, Yuzhi Chen
BMC Neurosci. 2012; 13: 112. Published online 2012 Sep 19. doi: 10.1186/1471-2202-13-112
PMCID:
PMC3506489
ArticlePDF–2.9M
9.
Mutation in CUL4B, Which Encodes a Member of Cullin-RING Ubiquitin Ligase Complex, Causes X-Linked Mental Retardation
Yongxin Zou, Qiji Liu, Bingxi Chen, Xiyu Zhang, Chenhong Guo, Haibin Zhou, Jiangxia Li, Guimin Gao, Yishou Guo, Chuanzhu Yan, Jianjun Wei, Changshun Shao, Yaoqin Gong
Am J Hum Genet. 2007 Mar; 80(3): 561–566. Published online 2007 Jan 25. doi: 10.1086/512489
PMCID:
PMC1821105
ArticlePDF–763K
10.
Mutations in CUL4B, Which Encodes a Ubiquitin E3 Ligase Subunit, Cause an X-linked Mental Retardation Syndrome Associated with Aggressive Outbursts, Seizures, Relative Macrocephaly, Central Obesity, Hypogonadism, Pes Cavus, and Tremor
Patrick S.  Tarpey, F. Lucy  Raymond, Sarah  O’Meara, Sarah  Edkins, Jon  Teague, Adam  Butler, Ed  Dicks, Claire  Stevens, Calli  Tofts, Tim  Avis, Syd  Barthorpe, Gemma  Buck, Jennifer  Cole, Kristian  Gray, Kelly  Halliday, Rachel  Harrison, Katy  Hills, Andrew  Jenkinson, David  Jones, Andrew  Menzies, Tatiana  Mironenko, Janet  Perry, Keiran  Raine, David  Richardson, Rebecca  Shepherd, Alexandra  Small, Jennifer  Varian, Sofie  West, Sara  Widaa, Uma  Mallya, Jenny  Moon, Ying  Luo, Susan  Holder, Sarah F.  Smithson, Jane A.  Hurst, Jill  Clayton-Smith, Bronwyn  Kerr, Jackie  Boyle, Marie  Shaw, Lucianne  Vandeleur, Jayson  Rodriguez, Rachel  Slaugh, Douglas F.  Easton, Richard  Wooster, Martin  Bobrow, Anand K.  Srivastava, Roger E.  Stevenson, Charles E.  Schwartz, Gillian  Turner, Jozef  Gecz, P. Andrew  Futreal, Michael R.  Stratton, Michael  Partington
Am J Hum Genet. 2007 Feb; 80(2): 345–352. Published online 2007 Jan 4. doi: 10.1086/511134
PMCID:
PMC1785336
ArticlePDF–3.5M
11.
JAGGED1 expression in human embryos: correlation with the Alagille syndrome phenotype
E Jones, M Clement-Jones, D Wilson
J Med Genet. 2000 Sep; 37(9): 658–662. doi: 10.1136/jmg.37.9.658
PMCID:
PMC1734694
SummaryPDF–191K
12.
Cullin 4B Ubiquitin Ligase Is Important for Cell Survival and Regulates TGF-β1 Expression in Pleural Mesothelioma
Jessica Kreienbühl, Sakunthip Changkhong, Vanessa Orlowski, Michaela B. Kirschner, Isabelle Opitz, Mayura Meerang
Int J Mol Sci. 2023 Sep; 24(17): 13410. Published online 2023 Aug 29. doi: 10.3390/ijms241713410
PMCID:
PMC10487616
ArticlePDF–11M
13.
Discovery and characterization of potent And‐1 inhibitors for cancer treatment
Jing Li, Yi Zhang, Jing Sun, Leyuan Chen, Wenfeng Gou, Chi‐Wei Chen, Yuan Zhou, Zhuqing Li, David W. Chan, Ruili Huang, Huadong Pei, Wei Zheng, Yiliang Li, Menghang Xia, Wenge Zhu
Clin Transl Med. 2021 Dec; 11(12): e627. Published online 2021 Dec 19. doi: 10.1002/ctm2.627
PMCID:
PMC8684776
ArticlePDF–6.3M
14.
Dysregulation of the miR‐194–CUL4B negative feedback loop drives tumorigenesis in non‐small‐cell lung carcinoma
Jun Mi, Yongxin Zou, Xiaohua Lin, Juanjuan Lu, Xiaochen liu, Hui Zhao, Xiang Ye, Huili Hu, Baichun Jiang, Bo Han, Changshun Shao, Yaoqin Gong
Mol Oncol. 2017 Mar; 11(3): 305–319. Published online 2017 Feb 21. doi: 10.1002/1878-0261.12038
PMCID:
PMC5527444
ArticlePDF–1.6M
15.
Dysregulation of CUL4A and CUL4B Ubiquitin Ligases in Lung Cancer
Lei Jia, Fan Yan, Wenfeng Cao, Zhengming Chen, Hong Zheng, Haixin Li, Yi Pan, Navneet Narula, Xiubao Ren, Hui Li, Pengbo Zhou
J Biol Chem. 2017 Feb 17; 292(7): 2966–2978. Published online 2016 Dec 14. doi: 10.1074/jbc.M116.765230
PMCID:
PMC5314191
ArticlePDF–4.1M
16.
Variants in CUL4B are Associated with Cerebral Malformations
Anneke T. Vulto-van Silfhout, Tadashi Nakagawa, Nadia Bahi-Buisson, Stefan A. Haas, Hao Hu, Melanie Bienek, Lisenka E.L.M. Vissers, Christian Gilissen, Andreas Tzschach, Andreas Busche, Jörg Müsebeck, Patrick Rump, Inge B. Mathijssen, Kristiina Avela, Mirja Somer, Fatma Doagu, Anju K. Philips, Anita Rauch, Alessandra Baumer, Krysta Voesenek, Karine Poirier, Jacqueline Vigneron, Daniel Amram, Sylvie Odent, Magdalena Nawara, Ewa Obersztyn, Jacek Lenart, Agnieszka Charzewska, Nicolas Lebrun, Ute Fischer, Willy M. Nillesen, Helger G. Yntema, Irma Järvelä, Hans-Hilger Ropers, Bert B.A. de Vries, Han G. Brunner, Hans van Bokhoven, F. Lucy Raymond, Michèl A.A.P. Willemsen, Jamel Chelly, Yue Xiong, A. James Barkovich, Vera M. Kalscheuer, Tjitske Kleefstra, Arjan P.M. de Brouwer
Hum Mutat. Author manuscript; available in PMC 2015 Oct 16.
Published in final edited form as: Hum Mutat. 2015 Jan; 36(1): 106–117. doi: 10.1002/humu.22718
PMCID:
PMC4608231
ArticlePDF–892K
17.
Mutations in Cullin 4B result in a human syndrome associated with increased camptothecin-induced topoisomerase I-dependent DNA breaks
Claudia Kerzendorfer, Annabel Whibley, Gillian Carpenter, Emily Outwin, Shih-Chieh Chiang, Gillian Turner, Charles Schwartz, Sherif El-Khamisy, F. Lucy Raymond, Mark O'Driscoll
Hum Mol Genet. 2010 Apr 1; 19(7): 1324–1334. Published online 2010 Jan 11. doi: 10.1093/hmg/ddq008
PMCID:
PMC2838540
ArticlePDF–364K
18.
Aurora kinase a promotes the progression of papillary thyroid carcinoma by activating the mTORC2-AKT signalling pathway
Zewei Zhao, Huijuan Wang, Ning Kang, Zhongyu Wang, Xiukun Hou, Linfei Hu, Shuo Qie, Jianping Guo, Songfeng Wei, Xianhui Ruan, Xiangqian Zheng
Cell Biosci. 2022; 12: 195. Published online 2022 Dec 5. doi: 10.1186/s13578-022-00934-z
PMCID:
PMC9721059
ArticlePDF–3.3M
19.
CUL4B facilitates HBV replication by promoting HBx stabilization
Haixia Shan, Bo Wang, Xiaodong Zhang, Hui Song, Xi Li, Yongxin Zou, Baichun Jiang, Huili Hu, Hao Dou, Changshun Shao, Lifen Gao, Chunhong Ma, Xiaoyun Yang, Xiaohong Liang, Yaoqin Gong
Cancer Biol Med. 2022 Jan 15; 19(1): 120–131. Published online 2022 Jan 15. doi: 10.20892/j.issn.2095-3941.2020.0468
PMCID:
PMC8763003
ArticlePDF–606K
20.
CUL4high Lung Adenocarcinomas Are Dependent on the CUL4-p21 Ubiquitin Signaling for Proliferation and Survival
Yannan Wang, Fan Yan, Abu Nasar, Zhe-Sheng Chen, Nasser Khaled Altorki, Brendon Stiles, Navneet Narula, Pengbo Zhou
Am J Pathol. 2021 Sep; 191(9): 1638–1650. doi: 10.1016/j.ajpath.2021.05.018
PMCID:
PMC8420861
ArticlePDF–2.4M

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