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Select item 109727031.

Maturity-onset diabetes of the young type 7 (MODY7) and mutation in the Krüppel-like transcription factor 11 (KLF11) gene

Y Wang, X Ye, X Chen, H Zang, Q Shen, L Chen

QJM. 2024 Mar; 117(3): 219–222. Published online 2023 Nov 11. doi: 10.1093/qjmed/hcad257

PMCID:: PMC10972703

Article PDF–1.1M

Select item 104682872.

KLF11 Protects against Venous Thrombosis via Suppressing Tissue Factor Expression

Wenying Liang, Haocheng Lu, Jinjian Sun, Guizhen Zhao, Huilun Wang, Yanhong Guo, Daniel Eitzman, Y Eugene Chen, Yanbo Fan, Jifeng Zhang

Thromb Haemost. Author manuscript; available in PMC 2023 Aug 30.

Published in final edited form as: Thromb Haemost. 2022 May; 122(5): 777–788. Published online 2021 Aug 24. doi: 10.1055/s-0041-1735191

PMCID:: PMC10468287

Abstract Article PDF–1.6M

Select item 94168453.

KLF11 Is a Novel Endogenous Protectant against Renal Ischemia-Reperfusion Injury

Karl A. Nath, Raman Deep Singh, Anthony J. Croatt, Allan W. Ackerman, Joseph P. Grande, Khasayarsha Khazaie, Y. Eugene Chen, Jifeng Zhang

Kidney360. 2022 Aug 25; 3(8): 1417–1422. Published online 2022 May 6. doi: 10.34067/KID.0002272022

PMCID:: PMC9416845

Abstract Article PDF–1.8M

Select item 94168414.

Endothelial KLF11 as a Nephroprotectant in AKI

Gelare Ghajar-Rahimi, Anupam Agarwal

Kidney360. 2022 Aug 25; 3(8): 1302–1305. Published online 2022 Aug 25. doi: 10.34067/KID.0003422022

PMCID:: PMC9416841

Article PDF–620K

Select item 78702965.

Clinical and Functional Characteristics of a Novel KLF11 Cys354Phe Variant Involved in Maturity-Onset Diabetes of the Young

Yujing Sun, Jingru Qu, Jing Wang, Ruxing Zhao, Chuan Wang, Li Chen, Xinguo Hou

J Diabetes Res. 2021; 2021: 7136869. Published online 2021 Feb 1. doi: 10.1155/2021/7136869

PMCID:: PMC7870296

Abstract Article PDF–1.9M

Select item 78401256.

Genome-wide CRISPR-Cas9 screen identified KLF11 as a druggable suppressor for sarcoma cancer stem cells

Yicun Wang, Jinhui Wu, Hui Chen, Yang Yang, Chengwu Xiao, Xiaoming Yi, Changjie Shi, Ke Zhong, Haowei He, Yaoming Li, Zhenjie Wu, Guangxin Zhou, Qiu Rao, Xiaoxia Wang, Xiaodie Zhou, Gwen Lomberk, Bing Liu, Jianning Zhao, Jingping Ge, Wenquan Zhou, Xiaoyuan Chu, Cheng Chen, Xuhui Zhou, Linhui Wang, Kunliang Guan, Le Qu

Sci Adv. 2021 Jan; 7(5): eabe3445. Published online 2021 Jan 27. doi: 10.1126/sciadv.abe3445

PMCID:: PMC7840125

Abstract Article PDF–3.7M

Select item 75781537.

DNA hypomethylation of the Krüppel-like factor 11 (KLF11) gene promoter: a putative biomarker of depression comorbidity in panic disorder and of non-anxious depression?

Leonie Kollert, Miriam A. Schiele, Christiane Thiel, Andreas Menke, Jürgen Deckert, Katharina Domschke

J Neural Transm (Vienna) 2020; 127(11): 1539–1546. Published online 2020 Jun 10. doi: 10.1007/s00702-020-02216-9

PMCID:: PMC7578153

Abstract Article PDF–679K

Select item 42815668.

Browning of human adipocytes requires KLF11 and reprogramming of PPARγ superenhancers

Anne Loft, Isabel Forss, Majken Storm Siersbæk, Søren Fisker Schmidt, Ann-Sofie Bøgh Larsen, Jesper Grud Skat Madsen, Didier F. Pisani, Ronni Nielsen, Mads Malik Aagaard, Angela Mathison, Matt J. Neville, Raul Urrutia, Fredrik Karpe, Ez-Zoubir Amri, Susanne Mandrup

Genes Dev. 2015 Jan 1; 29(1): 7–22. doi: 10.1101/gad.250829.114

PMCID:: PMC4281566

Abstract Article PDF–1.7M

Select item 40494859.

Single and combinatorial chromatin coupling events underlies the function of transcript factor krüppel-like factor 11 in the regulation of gene networks

Ezequiel Calvo, Adrienne Grzenda, Gwen Lomberk, Angela Mathison, Juan Iovanna, Raul Urrutia

BMC Mol Biol. 2014; 15: 10. Published online 2014 May 25. doi: 10.1186/1471-2199-15-10

PMCID:: PMC4049485

Abstract Article PDF–1.6M

Select item 394692010.

The Expression of KLF11 (TIEG2), an MAO B-transcriptional activator in the Prefrontal Cortex of Human Alcohol Dependence

Chinelo Udemgba, Shakevia Johnson, Craig A. Stockmeier, Jia Luo, Paul R. Albert, Junming Wang, Warren L. May, Sharonda Harris, Donald B. Sittman, Xiao-Ming Ou

Alcohol Clin Exp Res. Author manuscript; available in PMC 2014 Mar 8.

Published in final edited form as: Alcohol Clin Exp Res. 2014 Jan; 38(1): 144–151. Published online 2013 Aug 5. doi: 10.1111/acer.12229

PMCID:: PMC3946920

Abstract Article PDF–339K

Select item 368257411.

Krüppel-like Factor 11 Regulates the Expression of Metabolic Genes via an Evolutionarily Conserved Protein Interaction Domain Functionally Disrupted in Maturity Onset Diabetes of the Young

Gwen Lomberk, Adrienne Grzenda, Angela Mathison, Carlos Escande, Jin-San Zhang, Ezequiel Calvo, Laurence J. Miller, Juan Iovanna, Eduardo N. Chini, Martin E. Fernandez-Zapico, Raul Urrutia

J Biol Chem. 2013 Jun 14; 288(24): 17745–17758. Published online 2012 Apr 15. doi: 10.1074/jbc.M112.434670

PMCID:: PMC3682574

Abstract Article PDF–3.6M

Select item 322823712.

The association of genetic variants in Krüppel-like factor 11 and Type 2 diabetes in the Japanese population

T Tanahashi, K Shinohara, P Keshavarz, Y Yamaguchi, K Miyawaki, K Kunika, M Moritani, N Nakamura, T Yoshikawa, H Shiota, H Inoue, M Itakura

Diabet Med. 2008 Jan; 25(1): 19–26. doi: 10.1111/j.1464-5491.2007.02315.x

PMCID:: PMC3228237

Abstract Article PDF–388K

Select item 285702213.

Distinct Role of Kruppel-like Factor 11 in the Regulation of Prostaglandin E₂ Biosynthesis

Navtej S. Buttar, Cathrine J. DeMars, Gwen Lomberk, Sumera Rizvi, Juliana Bonilla-Velez, Shalini Achra, Shahrooz Rashtak, Kenneth K. Wang, Martin E. Fernandez-Zapico, Raul Urrutia

J Biol Chem. 2010 Apr 9; 285(15): 11433–11444. Published online 2010 Feb 12. doi: 10.1074/jbc.M109.077065

PMCID:: PMC2857022

Abstract Article PDF–3.5M

Select item 272923414.

Association Analysis of Krüppel-Like Factor 11 Variants with Type 2 Diabetes in Pima Indians

Lijun Ma, Robert L. Hanson, Lorem N. Que, Janel L. Mack, Paul W. Franks, Aniello M. Infante, Sayuko Kobes, Clifton Bogardus, Leslie J. Baier

J Clin Endocrinol Metab. 2008 Sep; 93(9): 3644–3649. Published online 2008 Jul 1. doi: 10.1210/jc.2008-0546

PMCID:: PMC2729234

Abstract Article

Select item 8414915.

FKLF, a Novel Krüppel-Like Factor That Activates Human Embryonic and Fetal β-Like Globin Genes

Haruhiko Asano, Xi Susan Li, George Stamatoyannopoulos

Mol Cell Biol. 1999 May; 19(5): 3571–3579. doi: 10.1128/mcb.19.5.3571

PMCID:: PMC84149

Abstract Article PDF–800K

Select item 1022701616.

KLF11 regulates lung adenocarcinoma ferroptosis and chemosensitivity by suppressing GPX4

Guangyin Zhao, Jiaqi Liang, Guangyao Shan, Jie Gu, Fengkai Xu, Chunlai Lu, Teng Ma, Guoshu Bi, Cheng Zhan, Di Ge

Commun Biol. 2023; 6: 570. Published online 2023 May 29. doi: 10.1038/s42003-023-04959-z

PMCID:: PMC10227016

Abstract Article PDF–5.8M

Select item 802110717.

KLF11 protects against abdominal aortic aneurysm through inhibition of endothelial cell dysfunction

Guizhen Zhao, Ziyi Chang, Yang Zhao, Yanhong Guo, Haocheng Lu, Wenying Liang, Oren Rom, Huilun Wang, Jinjian Sun, Tianqing Zhu, Yanbo Fan, Lin Chang, Bo Yang, Minerva T. Garcia-Barrio, Y. Eugene Chen, Jifeng Zhang

JCI Insight. 2021 Mar 8; 6(5): e141673. Published online 2021 Mar 8. doi: 10.1172/jci.insight.141673

PMCID:: PMC8021107

Abstract Article PDF–4.3M

Select item 377572918.

Role for Krüppel-Like Transcription Factor 11 in Mesenchymal Cell Function and Fibrosis

Angela Mathison, Adrienne Grzenda, Gwen Lomberk, Gabriel Velez, Navtej Buttar, Pamela Tietz, Helen Hendrickson, Ann Liebl, Yuning Y. Xiong, Gregory Gores, Martin Fernandez-Zapico, Nicholas F. LaRusso, William Faubion, Vijay H. Shah, Raul Urrutia

PLoS One. 2013; 8(9): e75311. Published online 2013 Sep 17. doi: 10.1371/journal.pone.0075311

PMCID:: PMC3775729

Abstract Article PDF–3.4M

Select item 355638719.

Krüppel Like Factor 11, a Transcription Factor Involved in Diabetes, Suppresses Endothelial Cell Activation via the NF-κB signaling pathway: Fan, KLF11 Inhibits Endothelial Inflammation

Yanbo Fan, Yanhong Guo, Jifeng Zhang, Malayannan Subramaniam, Chao-Zhong Song, Raul Urrutia, Y. Eugene Chen

Arterioscler Thromb Vasc Biol. Author manuscript; available in PMC 2013 Dec 1.

Published in final edited form as: Arterioscler Thromb Vasc Biol. 2012 Dec; 32(12): 2981–2988. Published online 2012 Oct 4. doi: 10.1161/ATVBAHA.112.300349

PMCID:: PMC3556387

Abstract Article PDF–4.3M

Select item 339784620.

Mechanistic Role for a Novel Glucocorticoid-KLF11 (TIEG2) Protein Pathway in Stress-induced Monoamine Oxidase A Expression

Matthew Grunewald, Shakevia Johnson, Deyin Lu, Zhe Wang, Gwen Lomberk, Paul R. Albert, Craig A. Stockmeier, Jeffrey H. Meyer, Raul Urrutia, Klaus A. Miczek, Mark C. Austin, Junming Wang, Ian A. Paul, William L. Woolverton, Seungmae Seo, Donald B. Sittman, Xiao-Ming Ou

J Biol Chem. 2012 Jul 13; 287(29): 24195–24206. Published online 2012 May 24. doi: 10.1074/jbc.M112.373936