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Items: 1 to 20 of 183

1.
Increased TRIM5 is associated with a poor prognosis and immune infiltration in glioma patients
Yue CHEN, Qin LI, Jie ZHANG, Rui GU, Kai LI, Gang ZHAO, Hang YUAN, Tianyu FENG, Deqiong OU, Ping LIN
Sheng Wu Yi Xue Gong Cheng Xue Za Zhi. 2020 Jun; 37(3): 469–479. doi: 10.7507/1001-5515.202004064
PMCID:
PMC10319560
ArticlePDF–9.3M
2.
A frequent SNP in TRIM5α strongly enhances the innate immune response against LINE-1 elements
Justine Lagisquet, Marcus Conrad, Sabine Wittmann, Bianca Volkmann, Hannah Weissinger, Heinrich Sticht, Thomas Gramberg
Front Immunol. 2023; 14: 1168589. Published online 2023 Apr 26. doi: 10.3389/fimmu.2023.1168589
PMCID:
PMC10169663
ArticlePDF–5.4M
3.
The retroviral restriction factor TRIM5/TRIM5α regulates mitochondrial quality control
Bhaskar Saha, Michael A. Mandell
Autophagy. 2023; 19(1): 372–373. Published online 2022 Jun 5. doi: 10.1080/15548627.2022.2084863
PMCID:
PMC9809936
ArticlePDF–342K
4.
TRIM5α Restriction of HIV-1-N74D Viruses in Lymphocytes Is Caused by a Loss of Cyclophilin A Protection
Anastasia Selyutina, Lacy M. Simons, Karen A. Kirby, Angel Bulnes-Ramos, Pan Hu, Stefan G. Sarafianos, Judd F. Hultquist, Felipe Diaz-Griffero
Viruses. 2022 Feb; 14(2): 363. Published online 2022 Feb 10. doi: 10.3390/v14020363
PMCID:
PMC8879423
ArticlePDF–2.3M
5.
TRIM5α Restricts Flavivirus Replication by Targeting the Viral Protease for Proteasomal Degradation
Abhilash I. Chiramel, Nicholas R. Meyerson, Kristin L. McNally, Rebecca M. Broeckel, Vanessa R. Montoya, Omayra Méndez-Solís, Shelly J. Robertson, Gail L. Sturdevant, Kirk J. Lubick, Vinod Nair, Brian H. Youseff, Robin M. Ireland, Catharine M. Bosio, Kyusik Kim, Jeremy Luban, Vanessa M. Hirsch, R. Travis Taylor, Fadila Bouamr, Sara L. Sawyer, Sonja M. Best
Cell Rep. Author manuscript; available in PMC 2021 Dec 12.
Published in final edited form as: Cell Rep. 2019 Jun 11; 27(11): 3269–3283.e6. doi: 10.1016/j.celrep.2019.05.040
PMCID:
PMC8666140
ArticlePDF–2.9M
6.
Human TRIM5α: Autophagy Connects Cell-Intrinsic HIV-1 Restriction and Innate Immune Sensor Functioning
Alexandra P. M. Cloherty, Anusca G. Rader, Brandon Compeer, Carla M. S. Ribeiro
Viruses. 2021 Feb; 13(2): 320. Published online 2021 Feb 19. doi: 10.3390/v13020320
PMCID:
PMC7923229
ArticlePDF–2.8M
7.
Correlated cryogenic fluorescence microscopy and electron cryo-tomography shows that exogenous TRIM5α can form hexagonal lattices or autophagy aggregates in vivo
Stephen D. Carter, João I. Mamede, Thomas J. Hope, Grant J. Jensen
Proc Natl Acad Sci U S A. 2020 Nov 24; 117(47): 29702–29711. Published online 2020 Nov 5. doi: 10.1073/pnas.1920323117
PMCID:
PMC7703684
ArticlePDF–2.8M
8.
Mutational resilience of antiviral restriction favors primate TRIM5α in host-virus evolutionary arms races
Jeannette L Tenthorey, Candice Young, Afeez Sodeinde, Michael Emerman, Harmit S Malik
eLife. 2020; 9: e59988. Published online 2020 Sep 15. doi: 10.7554/eLife.59988
PMCID:
PMC7492085
ArticlePDF–3.1M
9.
Cyclophilin A Prevents HIV-1 Restriction in Lymphocytes by Blocking Human TRIM5α Binding to the Viral Core
Anastasia Selyutina, Mirjana Persaud, Lacy M. Simons, Angel Bulnes-Ramos, Cindy Buffone, Alicia Martinez-Lopez, Viviana Scoca, Francesca Di Nunzio, Joseph Hiatt, Alexander Marson, Nevan J. Krogan, Judd F. Hultquist, Felipe Diaz-Griffero
Cell Rep. Author manuscript; available in PMC 2020 Jul 15.
Published in final edited form as: Cell Rep. 2020 Mar 17; 30(11): 3766–3777.e6. doi: 10.1016/j.celrep.2020.02.100
PMCID:
PMC7363000
ArticlePDF–1.7M
10.
Type-I-IFN-Stimulated Gene TRIM5γ Inhibits HBV Replication by Promoting HBx Degradation
Guangyun Tan, Zhaohong Yi, Hongxiao Song, Fengchao Xu, Feng Li, Roghiyh Aliyari, Hong Zhang, Peishuang Du, Yanhua Ding, Junqi Niu, Xiaosong Wang, Lishan Su, F. Xiao-Feng Qin, Genhong Cheng
Cell Rep. Author manuscript; available in PMC 2020 Dec 10.
Published in final edited form as: Cell Rep. 2019 Dec 10; 29(11): 3551–3563.e3. doi: 10.1016/j.celrep.2019.11.041
PMCID:
PMC6996557
ArticlePDF–2.5M
11.
Defects in assembly explain reduced antiviral activity of the G249D polymorphism in human TRIM5α
Sevnur Kömürlü, Margret Bradley, Nikolai Smolin, Sabrina Imam, Raymond F. Pauszek, III, Seth L. Robia, David Millar, Emi E. Nakayama, Tatsuo Shioda, Edward M. Campbell
PLoS One. 2019; 14(3): e0212888. Published online 2019 Mar 19. doi: 10.1371/journal.pone.0212888
PMCID:
PMC6424450
ArticlePDF–2.2M
12.
HIV-1 capsids from B27/B57+ elite controllers escape Mx2 but are targeted by TRIM5α, leading to the induction of an antiviral state
Natacha Merindol, Mohamed El-Far, Mohamed Sylla, Nasser Masroori, Caroline Dufour, Jia-xin Li, Pearl Cherry, Mélodie B. Plourde, Cécile Tremblay, Lionel Berthoux
PLoS Pathog. 2018 Nov; 14(11): e1007398. Published online 2018 Nov 12. doi: 10.1371/journal.ppat.1007398
PMCID:
PMC6258467
ArticlePDF–3.3M
13.
Editing of the human TRIM5 gene to introduce mutations with the potential to inhibit HIV-1
Caroline Dufour, Alix Claudel, Nicolas Joubarne, Natacha Merindol, Tara Maisonnet, Nasser Masroori, Mélodie B. Plourde, Lionel Berthoux
PLoS One. 2018; 13(1): e0191709. Published online 2018 Jan 26. doi: 10.1371/journal.pone.0191709
PMCID:
PMC5786314
ArticlePDF–4.9M
14.
Effects of host restriction factors and the HTLV-1 subtype on susceptibility to HTLV-1-associated myelopathy/tropical spastic paraparesis
Satoshi Nozuma, Eiji Matsuura, Daisuke Kodama, Yuichi Tashiro, Toshio Matsuzaki, Ryuji Kubota, Shuji Izumo, Hiroshi Takashima
Retrovirology. 2017; 14: 26. Published online 2017 Apr 19. doi: 10.1186/s12977-017-0350-9
PMCID:
PMC5395872
ArticlePDF–2.1M
15.
TRIM5α Degradation via Autophagy Is Not Required for Retroviral Restriction
Sabrina Imam, Sarah Talley, Rachel S. Nelson, Adarsh Dharan, Christopher O'Connor, Thomas J. Hope, Edward M. Campbell
J Virol. 2016 Apr 1; 90(7): 3400–3410. Prepublished online 2016 Jan 13. Published online 2016 Mar 11. doi: 10.1128/JVI.03033-15
PMCID:
PMC4794682
ArticlePDF–1.9M
16.
Preclinical Assessment of Mutant Human TRIM5α as an Anti-HIV-1 Transgene
Ulrike Jung, Kevin Urak, Maxime Veillette, Marie-Édith Nepveu-Traversy, Quang Toan Pham, Sophie Hamel, John J. Rossi, Lionel Berthoux
Hum Gene Ther. 2015 Oct 1; 26(10): 664–679. Published online 2015 Jun 12. doi: 10.1089/hum.2015.059
PMCID:
PMC4630796
ArticlePDF–613K
17.
TRIM5α Variations Influence Transduction Efficiency With Lentiviral Vectors in Both Human and Rhesus CD34+ Cells In Vitro and In Vivo
Molly E Evans, Chutima Kumkhaek, Matthew M Hsieh, Robert E Donahue, John F Tisdale, Naoya Uchida
Mol Ther. 2014 Feb; 22(2): 348–358. Prepublished online 2013 Oct 23. Published online 2013 Dec 10. doi: 10.1038/mt.2013.256
PMCID:
PMC3916046
ArticlePDF–550K
18.
Viral Attachment Induces Rapid Recruitment of an Innate Immune Sensor (TRIM5α) to the Plasma Membrane
Seiga Ohmine, Raman Deep Singh, David L. Marks, Melissa A. Meyer, Richard E. Pagano, Yasuhiro Ikeda
J Innate Immun. 2013 Jun; 5(4): 414–424. Published online 2013 Mar 21. doi: 10.1159/000346963
PMCID:
PMC3758239
ArticlePDF–459K
19.
Retrovirus Restriction by TRIM5 Proteins Requires Recognition of Only a Small Fraction of Viral Capsid Subunits
Jiong Shi, David B. Friedman, Christopher Aiken
J Virol. 2013 Aug; 87(16): 9271–9278. doi: 10.1128/JVI.00713-13
PMCID:
PMC3754041
ArticlePDF–2.5M
20.
Fates of Retroviral Core Components during Unrestricted and TRIM5-Restricted Infection
Sebla B. Kutluay, David Perez-Caballero, Paul D. Bieniasz
PLoS Pathog. 2013 Mar; 9(3): e1003214. Published online 2013 Mar 7. doi: 10.1371/journal.ppat.1003214
PMCID:
PMC3591316
ArticlePDF–1.9M

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