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Items: 1 to 20 of 31

1.
ELL and EAF1 are Cajal Body Components That Are Disrupted in MLL-ELL Leukemia
Paul E. Polak, Federico Simone, Joseph J. Kaberlein, Roger T. Luo, Michael J. Thirman
Mol Biol Cell. 2003 Apr; 14(4): 1517–1528. doi: 10.1091/mbc.E02-07-0394
Correction in:
Mol Biol Cell. 2003 May; 14(5): 0.
PMCID:
PMC153119
AbstractArticlePDF–1.0M
2.
ATM-mediated ELL phosphorylation enhances its self-association through increased EAF1 interaction and inhibits global transcription during genotoxic stress
Sujay Pal, Dipika Yadav, Debabrata Biswas
Nucleic Acids Res. 2022 Oct 28; 50(19): 10995–11012. Published online 2022 Oct 28. doi: 10.1093/nar/gkac943
Correction in:
Nucleic Acids Res. 2023 Jul 7; 51(12): 6507.
PMCID:
PMC9638944
AbstractArticlePDF–5.3M
3.
ELL-associated factors 1 and 2 are positive regulators of RNA polymerase II elongation factor ELL
Stephanie E. Kong, Charles A. S. Banks, Ali Shilatifard, Joan Weliky Conaway, Ronald C. Conaway
Proc Natl Acad Sci U S A. 2005 Jul 19; 102(29): 10094–10098. Published online 2005 Jul 8. doi: 10.1073/pnas.0503017102
PMCID:
PMC1177379
AbstractArticlePDF–354K
4.
FB1, an E2A fusion partner in childhood leukemia, interacts with U19/EAF2 and inhibits its transcriptional activity
Feng Jiang, Junkui Ai, Wuhan Xiao, Zhou Wang
Cancer Lett. Author manuscript; available in PMC 2008 Aug 18.
Published in final edited form as: Cancer Lett. 2007 Aug 18; 253(2): 265–272. Published online 2007 Mar 28. doi: 10.1016/j.canlet.2007.02.003
PMCID:
PMC1989770
AbstractArticlePDF–757K
5.
Negative Feedback Regulation of Wnt4 Signaling by EAF1 and EAF2/U19
Xiaoyang Wan, Wei Ji, Xue Mei, Jiangang Zhou, Jing-xia Liu, Chengchi Fang, Wuhan Xiao
PLoS One. 2010; 5(2): e9118. Published online 2010 Feb 9. doi: 10.1371/journal.pone.0009118
PMCID:
PMC2817739
AbstractArticlePDF–2.9M
6.
Negative Feedback Loop Mechanism between EAF1/2 and DBC1 in Regulating ELL Stability and Functions
Subham Basu, Arijit Nandy, Mahesh K. Barad, Sujay Pal, Debabrata Biswas
Mol Cell Biol. 2022 Oct; 42(10): e00151-22. Published online 2022 Aug 29. doi: 10.1128/mcb.00151-22
PMCID:
PMC9590304
AbstractArticlePDF–3.2M
7.
DBC1, p300, HDAC3, and Siah1 coordinately regulate ELL stability and function for expression of its target genes
Subham Basu, Mahesh Barad, Dipika Yadav, Arijit Nandy, Bidisha Mukherjee, Jit Sarkar, Partha Chakrabarti, Satinath Mukhopadhyay, Debabrata Biswas
Proc Natl Acad Sci U S A. 2020 Mar 24; 117(12): 6509–6520. Published online 2020 Mar 9. doi: 10.1073/pnas.1912375117
PMCID:
PMC7104407
AbstractArticlePDF–2.5M
8.
The little elongation complex (LEC) regulates small nuclear RNA transcription
Edwin R. Smith, Chengqi Lin, Alexander S. Garrett, Janet Thornton, Nima Mohaghegh, Deqing Hu, Jessica Jackson, Anita Saraf, Selene K. Swanson, Christopher Seidel, Laurence Florens, Michael P. Washburn, Joel C. Eissenberg, Ali Shilatifard
Mol Cell. Author manuscript; available in PMC 2012 Dec 23.
Published in final edited form as: Mol Cell. 2011 Dec 23; 44(6): 954–965. doi: 10.1016/j.molcel.2011.12.008
PMCID:
PMC3249835
AbstractArticlePDF–1.6M
9.
Human Mediator Subunit Med26 Functions As A Docking Site For Transcription Elongation Factors
Hidehisa Takahashi, Tari J. Parmely, Shigeo Sato, Chieri Tomomori-Sato, Charles A. S. Banks, Stephanie E. Kong, Henrietta Szutorisz, Selene K. Swanson, Skylar Martin-Brown, Michael P. Washburn, Laurence Florens, Chris Seidel, Chengqi Lin, Edwin R. Smith, Ali Shilatifard, Ronald C. Conaway, Joan W. Conaway
Cell. Author manuscript; available in PMC 2012 Jul 8.
Published in final edited form as: Cell. 2011 Jul 8; 146(1): 92–104. doi: 10.1016/j.cell.2011.06.005
PMCID:
PMC3145325
AbstractArticlePDF–1.9M
10.
The nuclear interactome of DYRK1A reveals a functional role in DNA damage repair
Steven E. Guard, Zachary C. Poss, Christopher C. Ebmeier, Maria Pagratis, Helen Simpson, Dylan J. Taatjes, William M. Old
Sci Rep. 2019; 9: 6539. Published online 2019 Apr 25. doi: 10.1038/s41598-019-42990-5
PMCID:
PMC6483993
AbstractArticlePDF–2.2M
11.
Combinatorial CRISPR screen identifies fitness effects of gene paralogues
Nicola A. Thompson, Marco Ranzani, Louise van der Weyden, Vivek Iyer, Victoria Offord, Alastair Droop, Fiona Behan, Emanuel Gonçalves, Anneliese Speak, Francesco Iorio, James Hewinson, Victoria Harle, Holly Robertson, Elizabeth Anderson, Beiyuan Fu, Fengtang Yang, Guido Zagnoli-Vieira, Phil Chapman, Martin Del Castillo Velasco-Herrera, Mathew J. Garnett, Stephen P. Jackson, David J. Adams
Nat Commun. 2021; 12: 1302. Published online 2021 Feb 26. doi: 10.1038/s41467-021-21478-9
PMCID:
PMC7910459
AbstractArticlePDF–3.3M
12.
Pooled‐matrix protein interaction screens using Barcode Fusion Genetics
Nozomu Yachie, Evangelia Petsalaki, Joseph C Mellor, Jochen Weile, Yves Jacob, Marta Verby, Sedide B Ozturk, Siyang Li, Atina G Cote, Roberto Mosca, Jennifer J Knapp, Minjeong Ko, Analyn Yu, Marinella Gebbia, Nidhi Sahni, Song Yi, Tanya Tyagi, Dayag Sheykhkarimli, Jonathan F Roth, Cassandra Wong, Louai Musa, Jamie Snider, Yi‐Chun Liu, Haiyuan Yu, Pascal Braun, Igor Stagljar, Tong Hao, Michael A Calderwood, Laurence Pelletier, Patrick Aloy, David E Hill, Marc Vidal, Frederick P Roth
Mol Syst Biol. 2016 Apr; 12(4): 863. Published online 2016 Apr 23. doi: 10.15252/msb.20156660
PMCID:
PMC4848762
AbstractArticlePDF–2.8M
13.
Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity
Jae Jin Kim, Seo Yun Lee, Fade Gong, Anna M. Battenhouse, Daniel R. Boutz, Aarti Bashyal, Samantha T. Refvik, Cheng-Ming Chiang, Blerta Xhemalce, Tanya T. Paull, Jennifer S. Brodbelt, Edward M. Marcotte, Kyle M. Miller
Genes Dev. 2019 Dec 1; 33(23-24): 1751–1774. doi: 10.1101/gad.331231.119
PMCID:
PMC6942044
AbstractArticlePDF–10M
14.
Leveraging the power of next-generation sequencing to generate interactome datasets
Haiyuan Yu, Leah Tardivo, Stanley Tam, Evan Weiner, Fana Gebreab, Changyu Fan, Nenad Svrzikapa, Tomoko Hirozane-Kishikawa, Edward Rietman, Xinping Yang, Julie Sahalie, Kourosh Salehi-Ashtiani, Tong Hao, Michael E. Cusick, David E. Hill, Frederick P. Roth, Pascal Braun, Marc Vidal
Nat Methods. Author manuscript; available in PMC 2011 Dec 1.
Published in final edited form as: Nat Methods. 2011 Jun; 8(6): 478–480. Published online 2011 Apr 24. doi: 10.1038/nmeth.1597
PMCID:
PMC3188388
AbstractArticlePDF–932K
15.
Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers
Joseph Rosenbluh, Johnathan Mercer, Yashaswi Shrestha, Rachel Oliver, Pablo Tamayo, John G. Doench, Itay Tirosh, Federica Piccioni, Ella Hartenian, Heiko Horn, Lola Fagbami, David E. Root, Jacob Jaffe, Kasper Lage, Jesse S. Boehm, William C. Hahn
Cell Syst. Author manuscript; available in PMC 2017 Sep 28.
Published in final edited form as: Cell Syst. 2016 Sep 28; 3(3): 302–316.e4. doi: 10.1016/j.cels.2016.09.001
PMCID:
PMC5455996
AbstractArticlePDF–3.1M
16.
An organelle-specific protein landscape identifies novel diseases and molecular mechanisms
Karsten Boldt, Jeroen van Reeuwijk, Qianhao Lu, Konstantinos Koutroumpas, Thanh-Minh T. Nguyen, Yves Texier, Sylvia E. C. van Beersum, Nicola Horn, Jason R. Willer, Dorus A. Mans, Gerard Dougherty, Ideke J. C. Lamers, Karlien L. M. Coene, Heleen H. Arts, Matthew J. Betts, Tina Beyer, Emine Bolat, Christian Johannes Gloeckner, Khatera Haidari, Lisette Hetterschijt, Daniela Iaconis, Dagan Jenkins, Franziska Klose, Barbara Knapp, Brooke Latour, Stef J. F. Letteboer, Carlo L. Marcelis, Dragana Mitic, Manuela Morleo, Machteld M. Oud, Moniek Riemersma, Susan Rix, Paulien A. Terhal, Grischa Toedt, Teunis J. P. van Dam, Erik de Vrieze, Yasmin Wissinger, Ka Man Wu, Gordana Apic, Philip L. Beales, Oliver E. Blacque, Toby J. Gibson, Martijn A. Huynen, Nicholas Katsanis, Hannie Kremer, Heymut Omran, Erwin van Wijk, Uwe Wolfrum, François Kepes, Erica E. Davis, Brunella Franco, Rachel H. Giles, Marius Ueffing, Robert B. Russell, Ronald Roepman, UK10K Rare Diseases Group
Nat Commun. 2016; 7: 11491. Published online 2016 May 13. doi: 10.1038/ncomms11491
PMCID:
PMC4869170
AbstractArticlePDF–2.0M
17.
Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism
Michael Aregger, Keith A. Lawson, Maximillian Billmann, Michael Costanzo, Amy H. Y. Tong, Katherine Chan, Mahfuzur Rahman, Kevin R. Brown, Catherine Ross, Matej Usaj, Lucy Nedyalkova, Olga Sizova, Andrea Habsid, Judy Pawling, Zhen-Yuan Lin, Hala Abdouni, Cassandra J. Wong, Alexander Weiss, Patricia Mero, James W. Dennis, Anne-Claude Gingras, Chad L. Myers, Brenda J. Andrews, Charles Boone, Jason Moffat
Nat Metab. Author manuscript; available in PMC 2020 Dec 1.
Published in final edited form as: Nat Metab. 2020 Jun; 2(6): 499–513. Published online 2020 Jun 1. doi: 10.1038/s42255-020-0211-z
PMCID:
PMC7566881
AbstractArticlePDF–4.8M
18.
Ubiquitin-mediated proteolysis of HuR by heat shock
Kotb Abdelmohsen, Subramanya Srikantan, Xiaoling Yang, Ashish Lal, Hyeon Ho Kim, Yuki Kuwano, Stefanie Galban, Kevin G Becker, Davida Kamara, Rafael de Cabo, Myriam Gorospe
EMBO J. 2009 May 6; 28(9): 1271–1282. Published online 2009 Mar 26. doi: 10.1038/emboj.2009.67
PMCID:
PMC2683047
AbstractArticlePDF–1.4M
19.
Interactions of Pathological Hallmark Proteins: TUBULIN POLYMERIZATION PROMOTING PROTEIN/p25, β-AMYLOID, AND α-SYNUCLEIN
Judit Oláh, Orsolya Vincze, Dezső Virók, Dóra Simon, Zsolt Bozsó, Natália Tőkési, István Horváth, Emma Hlavanda, János Kovács, Anna Magyar, Mária Szűcs, Ferenc Orosz, Botond Penke, Judit Ovádi
J Biol Chem. 2011 Sep 30; 286(39): 34088–34100. Published online 2011 Aug 8. doi: 10.1074/jbc.M111.243907
PMCID:
PMC3190826
AbstractArticlePDF–5.7M
20.
Integrative oncogene-dependency mapping identifies RIT1 vulnerabilities and synergies in lung cancer
Athea Vichas, Amanda K. Riley, Naomi T. Nkinsi, Shriya Kamlapurkar, Phoebe C. R. Parrish, April Lo, Fujiko Duke, Jennifer Chen, Iris Fung, Jacqueline Watson, Matthew Rees, Austin M. Gabel, James D. Thomas, Robert K. Bradley, John K. Lee, Emily M. Hatch, Marina K. Baine, Natasha Rekhtman, Marc Ladanyi, Federica Piccioni, Alice H. Berger
Nat Commun. 2021; 12: 4789. Published online 2021 Aug 9. doi: 10.1038/s41467-021-24841-y
PMCID:
PMC8352964
AbstractArticlePDF–4.5M

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