PMC Links for Gene (Select 8694) - PMC

Xiang Cheng, Feng Geng, Meixia Pan, Xiaoning Wu, Yaogang Zhong, Chunyan Wang, Zhihua Tian, Chunming Cheng, Rui Zhang, Vinay Puduvalli, Craig Horbinski, Xiaokui Mo, Xianlin Han, Arnab Chakravarti, Deliang Guo

Cell Metab. Author manuscript; available in PMC 2021 Aug 4.

Published in final edited form as: Cell Metab. 2020 Aug 4; 32(2): 229–242.e8. Published online 2020 Jun 18. doi: 10.1016/j.cmet.2020.06.002

PMCID:: PMC7415721

Abstract Article PDF–3.7M

Select item 73985575.

Structure and catalytic mechanism of a human triglyceride synthesis enzyme

Xuewu Sui, Kun Wang, Nina L. Gluchowski, Shane D. Elliott, Maofu Liao, Tobias C. Walther, Robert V. Farese, Jr.

Nature. Author manuscript; available in PMC 2020 Nov 13.

Published in final edited form as: Nature. 2020 May; 581(7808): 323–328. Published online 2020 May 13. doi: 10.1038/s41586-020-2289-6

PMCID:: PMC7398557

Abstract Article PDF–6.4M

Select item 72550496.

Structure and mechanism of human diacylglycerol O-acyltransferase-1

Lie Wang, Hongwu Qian, Yin Nian, Yimo Han, Zhenning Ren, Hanzhi Zhang, Liya Hu, B. V. Venkataram Prasad, Arthur Laganowsky, Nieng Yan, Ming Zhou

Nature. Author manuscript; available in PMC 2020 Nov 13.

Published in final edited form as: Nature. 2020 May; 581(7808): 329–332. Published online 2020 May 13. doi: 10.1038/s41586-020-2280-2

PMCID:: PMC7255049

Abstract Article PDF–5.0M

Select item 61913157.

Reversible deficits in apical transporter trafficking associated with DGAT1 deficiency

Cameron Schlegel, Lynne A. Lapierre, Victoria G. Weis, Janice A. Williams, Izumi Kaji, Carolina Pinzon-Guzman, Nripesh Prasad, Braden Boone, Angela Jones, Hernan Correa, Shawn E. Levy, Xianlin Han, Miao Wang, Kelly Thomsen, Sari Acra, James R. Goldenring

Traffic. Author manuscript; available in PMC 2019 Nov 1.

Published in final edited form as: Traffic. 2018 Nov; 19(11): 879–892. Published online 2018 Sep 21. doi: 10.1111/tra.12608

PMCID:: PMC6191315

Abstract Article PDF–3.2M

Select item 54545188.

Identification and characterization of a novel DGAT1 missense mutation associated with congenital diarrhea

Nina L. Gluchowski, Chandramohan Chitraju, Joseph A. Picoraro, Niklas Mejhert, Shirly Pinto, Winnie Xin, Daniel S. Kamin, Harland S. Winter, Wendy K. Chung, Tobias C. Walther, Robert V. Farese, Jr.

J Lipid Res. 2017 Jun; 58(6): 1230–1237. Published online 2017 Apr 3. doi: 10.1194/jlr.P075119

PMCID:: PMC5454518

Abstract Article PDF–901K

Select item 49892159.

Congenital protein losing enteropathy: an inborn error of lipid metabolism due to DGAT1 mutations

Joshi Stephen, Thierry Vilboux, Yael Haberman, Hadass Pri-Chen, Ben Pode-Shakked, Sina Mazaheri, Dina Marek-Yagel, Ortal Barel, Ayelet Di Segni, Eran Eyal, Goni Hout-Siloni, Avishay Lahad, Tzippora Shalem, Gideon Rechavi, May Christine V Malicdan, Batia Weiss, William A Gahl, Yair Anikster

Eur J Hum Genet. 2016 Aug; 24(9): 1268–1273. Published online 2016 Feb 17. doi: 10.1038/ejhg.2016.5

PMCID:: PMC4989215

Abstract Article PDF–874K

Select item 471786310.

Prolonged silencing of diacylglycerol acyltransferase‐1 induces a dedifferentiated phenotype in human liver cells

Soyoung Chang, Pil Soo Sung, Jungsul Lee, Junseong Park, Eui‐Cheol Shin, Chulhee Choi

J Cell Mol Med. 2016 Jan; 20(1): 38–47. Published online 2015 Oct 23. doi: 10.1111/jcmm.12685

PMCID:: PMC4717863

Abstract Article PDF–1.9M

Select item 353355511.

DGAT1 mutation is linked to a congenital diarrheal disorder

Joel T. Haas, Harland S. Winter, Elaine Lim, Andrew Kirby, Brendan Blumenstiel, Matthew DeFelice, Stacey Gabriel, David Branski, Carrie A. Grueter, Mauro S. Toporovski, Tobias C. Walther, Mark J. Daly, Robert V. Farese, Jr., Chaim Jalas

J Clin Invest. 2012 Dec 3; 122(12): 4680–4684. Published online 2012 Nov 1. doi: 10.1172/JCI64873

PMCID:: PMC3533555

Abstract Article PDF–856K

Select item 343119912.

Efficient Hepatitis C Virus Particle Formation Requires Diacylglycerol Acyltransferase 1 (DGAT1)

Eva Herker, Charles Harris, Céline Hernandez, Arnaud Carpentier, Katrin Kaehlcke, Arielle R. Rosenberg, Robert V. Farese, Jr, Melanie Ott

Nat Med. Author manuscript; available in PMC 2012 Aug 30.

Published in final edited form as: Nat Med. 2010 Nov; 16(11): 1295–1298. Published online 2010 Oct 10. doi: 10.1038/nm.2238

PMCID:: PMC3431199

Abstract Article PDF–465K

Select item 272148013.

Visceral and Subcutaneous Adipose Tissue Diacylglycerol Acyltransferase Activity in Humans

X. Hou, S. Moser, M. Sarr, G. Thompson, F. Que, M.D. Jensen

Obesity (Silver Spring) Author manuscript; available in PMC 2009 Dec 1.

Published in final edited form as: Obesity (Silver Spring). 2009 Jun; 17(6): 1129–1134. Published online 2009 Feb 5. doi: 10.1038/oby.2008.659

PMCID:: PMC2721480

Abstract Article PDF–238K

Select item 1094729614.

The roles of DGAT1 and DGAT2 in human myotubes are dependent on donor patho‐physiological background

Zehra Irshad, Jenny Lund, Anne Sillars, Nils Gunnar Løvsletten, Seley Gharanei, Ian P. Salt, Dilys J. Freeman, Jason M. R. Gill, G. Hege Thoresen, Arild C. Rustan, Victor A. Zammit

FASEB J. 2023 Nov; 37(11): e23209. Published online 2023 Oct 1. doi: 10.1096/fj.202300960RR

PMCID:: PMC10947296

Abstract Article PDF–6.2M

Select item 1094615415.

The role of DGAT1 and DGAT2 in regulating tumor cell growth and their potential clinical implications

Boer Deng, Weimin Kong, Xiaochang Shen, Chao Han, Ziyi Zhao, Shuning Chen, Chunxiao Zhou, Victoria Bae-Jump

J Transl Med. 2024; 22: 290. Published online 2024 Mar 18. doi: 10.1186/s12967-024-05084-z

PMCID:: PMC10946154

Abstract Article PDF–1.2M

Select item 987382116.

DGKB mediates radioresistance by regulating DGAT1-dependent lipotoxicity in glioblastoma

Hyunkoo Kang, Haksoo Lee, Kyeongmin Kim, Eunguk Shin, Byeongsoo Kim, JiHoon Kang, Bohkyung Kim, Jung Sub Lee, Jae-Myung Lee, HyeSook Youn, BuHyun Youn

Cell Rep Med. 2023 Jan 17; 4(1): 100880. Published online 2023 Jan 4. doi: 10.1016/j.xcrm.2022.100880

PMCID:: PMC9873821

Abstract Article PDF–6.4M

Select item 939132017.

An Oncogenic JMJD6-DGAT1 Axis Tunes Epigenetic Regulation of Lipid Droplet Formation in Clear Cell Renal Cell Carcinoma

Jin Zhou, Jeremy M. Simon, Chengheng Liao, Cheng Zhang, Lianxin Hu, Giada Zurlo, Xijuan Liu, Cheng Fan, Austin Hepperla, Liwei Jia, Vanina Toffessi Tcheuyap, Hua Zhong, Roy Elias, Jin Ye, W. Mike Henne, Payal Kapur, Deepak Nijhawan, James Brugarolas, Qing Zhang

Mol Cell. Author manuscript; available in PMC 2023 Aug 18.

Published in final edited form as: Mol Cell. 2022 Aug 18; 82(16): 3030–3044.e8. Published online 2022 Jun 27. doi: 10.1016/j.molcel.2022.06.003

PMCID:: PMC9391320

Abstract Article PDF–3.0M

Select item 639566518.

DGAT1 Inhibitor Suppresses Prostate Tumor Growth and Migration by Regulating Intracellular Lipids and Non-Centrosomal MTOC Protein GM130

Francesca Nardi, Omar E. Franco, Philip Fitchev, Alejandro Morales, Renee E. Vickman, Simon W. Hayward, Susan E. Crawford

Sci Rep. 2019; 9: 3035. Published online 2019 Feb 28. doi: 10.1038/s41598-019-39537-z

PMCID:: PMC6395665

Abstract Article PDF–4.2M

Select item 619522619.

Triglyceride Synthesis by DGAT1 Protects Adipocytes from Lipid-Induced ER Stress during Lipolysis

Chandramohan Chitraju, Niklas Mejhert, Joel T. Haas, L. Grisell Diaz-Ramirez, Carrie A. Grueter, Jason E. Imbriglio, Shirly Pinto, Suneil K. Koliwad, Tobias C. Walther, Robert V. Farese, Jr

Cell Metab. Author manuscript; available in PMC 2018 Oct 19.

Published in final edited form as: Cell Metab. 2017 Aug 1; 26(2): 407–418.e3. doi: 10.1016/j.cmet.2017.07.012

PMCID:: PMC6195226

Abstract Article PDF–2.7M

Select item 605803520.

Intestinal Failure and Aberrant Lipid Metabolism in Patients With DGAT1 Deficiency

Jorik M. van Rijn, Rico Chandra Ardy, Zarife Kuloğlu, Bettina Härter, Désirée Y. van Haaften-Visser, Hubert P.J. van der Doef, Marliek van Hoesel, Aydan Kansu, Anke H.M. van Vugt, Marini Thian, Freddy T.M. Kokke, Ana Krolo, Meryem Keçeli Başaran, Neslihan Gurcan Kaya, Aysel Ünlüsoy Aksu, Buket Dalgıç, Figen Ozcay, Zeren Baris, Renate Kain, Edwin C.A. Stigter, Klaske D. Lichtenbelt, Maarten P.G. Massink, Karen J. Duran, Joke B.G.M Verheij, Dorien Lugtenberg, Peter G.J. Nikkels, Henricus G.F. Brouwer, Henkjan J. Verkade, René Scheenstra, Bart Spee, Edward E.S. Nieuwenhuis, Paul J. Coffer, Andreas R. Janecke, Gijs van Haaften, Roderick H.J. Houwen, Thomas Müller, Sabine Middendorp, Kaan Boztug

Gastroenterology. 2018 Jul; 155(1): 130–143.e15. doi: 10.1053/j.gastro.2018.03.040

PMCID:: PMC6058035

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