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Select item 88064121.

α-Actinin1 promotes tumorigenesis and epithelial-mesenchymal transition of gastric cancer via the AKT/GSK3β/β-Catenin pathway

Siwen Zhang, Junfu Wang, Ting Chen, Jiancheng Wang, Ye Wang, Zhu Yu, Kun Zhao, Kaitian Zheng, Yeyang Chen, Zhen Wang, Bopei Li, Congjun Wang, Weijia Huang, Zhao Fu, Junqiang Chen

Bioengineered. 2021; 12(1): 5688–5704. Published online 2021 Sep 21. doi: 10.1080/21655979.2021.1967713

PMCID:: PMC8806412

Abstract Article PDF–3.9M

Select item 77919912.

ACTN1 supports tumor growth by inhibiting Hippo signaling in hepatocellular carcinoma

Qian Chen, Xiao-Wei Zhou, Ai-Jun Zhang, Kang He

J Exp Clin Cancer Res. 2021; 40: 23. Published online 2021 Jan 7. doi: 10.1186/s13046-020-01821-6

Correction in:: J Exp Clin Cancer Res. 2021; 40: 128.

PMCID:: PMC7791991

Abstract Article PDF–2.4M

Select item 72113283.

High ACTN1 Is Associated with Poor Prognosis, and ACTN1 Silencing Suppresses Cell Proliferation and Metastasis in Oral Squamous Cell Carcinoma

Guo-feng Xie, Luo-dan Zhao, Qiang Chen, Dong-xiao Tang, Qiong-yu Chen, Hong-fei Lu, Jia-rong Cai, Zheng Chen

Drug Des Devel Ther. 2020; 14: 1717–1727. Published online 2020 May 5. doi: 10.2147/DDDT.S244516

PMCID:: PMC7211328

Abstract Article PDF–7.8M

Select item 69001414.

Novel ACTN1 variants in cases of thrombocytopenia

Anne Vincenot, Paul Saultier, Shinji Kunishima, Marjorie Poggi, Marie‐Françoise Hurtaud‐Roux, Alain Roussel, ACTN1 study coinvestigators, Nicole Schlegel, Marie‐Christine Alessi

Hum Mutat. 2019 Dec; 40(12): 2258–2269. Published online 2019 Nov 6. doi: 10.1002/humu.23840

PMCID:: PMC6900141

Abstract Article PDF–4.0M

Select item 56272755.

Energy stress-induced lncRNA FILNC1 represses c-Myc-mediated energy metabolism and inhibits renal tumor development

Zhen-Dong Xiao, Leng Han, Hyemin Lee, Li Zhuang, Yilei Zhang, Joelle Baddour, Deepak Nagrath, Christopher G. Wood, Jian Gu, Xifeng Wu, Han Liang, Boyi Gan

Nat Commun. 2017; 8: 783. Published online 2017 Oct 4. doi: 10.1038/s41467-017-00902-z

PMCID:: PMC5627275

Abstract Article PDF–1.1M

Select item 48953826.

Structure and calcium-binding studies of calmodulin-like domain of human non-muscle α-actinin-1

Sara Drmota Prebil, Urška Slapšak, Miha Pavšič, Gregor Ilc, Vid Puž, Euripedes de Almeida Ribeiro, Dorothea Anrather, Markus Hartl, Lars Backman, Janez Plavec, Brigita Lenarčič, Kristina Djinović-Carugo

Sci Rep. 2016; 6: 27383. Published online 2016 Jun 7. doi: 10.1038/srep27383

PMCID:: PMC4895382

Abstract Article PDF–1.9M

Select item 43663077.

Alpha actinin-1 regulates cell-matrix adhesion organization in keratinocytes: consequences for skin cell motility

Kevin J. Hamill, Sho Hiroyasu, Zachary T. Colburn, Rosa V. Ventrella, Susan B. Hopkinson, Omar Skalli, Jonathan C. R. Jones

J Invest Dermatol. Author manuscript; available in PMC 2015 Oct 1.

Published in final edited form as: J Invest Dermatol. 2015 Apr; 135(4): 1043–1052. Published online 2014 Nov 28. doi: 10.1038/jid.2014.505

PMCID:: PMC4366307

Abstract Article PDF–2.3M

Select item 43112328.

Roberta Bottega, Caterina Marconi, Michela Faleschini, Gabriele Baj, Claudia Cagioni, Alessandro Pecci, Tommaso Pippucci, Ugo Ramenghi, Simonetta Pardini, Loretta Ngu, Carlo Baronci, Shinji Kunishima, Carlo L. Balduini, Marco Seri, Anna Savoia, Patrizia Noris

Blood. 2015 Jan 29; 125(5): 869–872. Prepublished online 2014 Oct 31. doi: 10.1182/blood-2014-08-594531

PMCID:: PMC4311232

Abstract Article

Select item 35678539.

Alpha Actinin is Specifically Recognized by Multiple Sclerosis Autoantibodies Isolated Using an N-Glucosylated Peptide Epitope

Shashank Pandey, Ilaria Dioni, Duccio Lambardi, Feliciana Real-Fernandez, Elisa Peroni, Giulia Pacini, Francesco Lolli, Roberta Seraglia, Anna Maria Papini, Paolo Rovero

Mol Cell Proteomics. 2013 Feb; 12(2): 277–282. Published online 2012 Nov 8. doi: 10.1074/mcp.M112.017087

PMCID:: PMC3567853

Abstract Article PDF–231K

Select item 274363910.

Mactinin, a fragment of cytoskeletal α-actinin, is a novel inducer of heat shock protein (Hsp)-90 mediated monocyte activation

Sharon D Luikart, Angela Panoskaltsis-Mortari, Timothy Hinkel, Robert T Perri, Kalpna Gupta, Theodore R Oegema, Pankaj Gupta

BMC Cell Biol. 2009; 10: 60. Published online 2009 Aug 28. doi: 10.1186/1471-2121-10-60

PMCID:: PMC2743639

Abstract Article PDF–786K

Select item 219073311.

Phosphoinositide binding regulates α-actinin CH2 domain structure: Analysis by hydrogen/deuterium exchange mass spectrometry

Stephen J. Full, Max L. Deinzer, P. Shing Ho, Jeffrey A. Greenwood

Protein Sci. 2007 Dec; 16(12): 2597–2604. doi: 10.1110/ps.073146807

PMCID:: PMC2190733

Abstract Article PDF–441K

Select item 168376512.

Cloning and chromosomal localization of the human cytoskeletal alpha-actinin gene reveals linkage to the beta-spectrin gene.

H Youssoufian, M McAfee, D J Kwiatkowski

Am J Hum Genet. 1990 Jul; 47(1): 62–71.

PMCID:: PMC1683765

Summary Page Browse PDF–2.8M

Select item 31836613.

The cDNA sequence of a human placental alpha-actinin.

D B Millake, A D Blanchard, B Patel, D R Critchley

Nucleic Acids Res. 1989 Aug 25; 17(16): 6725. doi: 10.1093/nar/17.16.6725

PMCID:: PMC318366

Summary Page Browse PDF–117K

Select item 12293514.

Functional consequences of caspase activation in cardiac myocytes

Catherine Communal, Marius Sumandea, Pieter de Tombe, Jagat Narula, R. John Solaro, Roger J. Hajjar

Proc Natl Acad Sci U S A. 2002 Apr 30; 99(9): 6252–6256. Published online 2002 Apr 23. doi: 10.1073/pnas.092022999

PMCID:: PMC122935

Abstract Article PDF–201K

Select item 869403815.

Distinct forms of the actin cross-linking protein α-actinin support macropinosome internalization and trafficking

Kevin M. Burton, Katherine M. Johnson, Eugene W. Krueger, Gina L. Razidlo, Mark A. McNiven

Mol Biol Cell. 2021 Jul 15; 32(15): 1393–1407. doi: 10.1091/mbc.E20-12-0755

PMCID:: PMC8694038

Abstract Article PDF–9.1M

Select item 844724316.

Actinin BioID reveals sarcomere crosstalk with oxidative metabolism through interactions with IGF2BP2

Feria A. Ladha, Ketan Thakar, Anthony M. Pettinato, Nicholas Legere, Shahnaz Ghahremani, Rachel Cohn, Robert Romano, Emily Meredith, Yu-Sheng Chen, J. Travis Hinson

Cell Rep. Author manuscript; available in PMC 2021 Sep 17.

Published in final edited form as: Cell Rep. 2021 Aug 10; 36(6): 109512. doi: 10.1016/j.celrep.2021.109512

PMCID:: PMC8447243

Abstract Article PDF–2.1M

Select item 686930417.

Topographic cues of a novel bilayered scaffold modulate dental pulp stem cells differentiation by regulating YAP signalling through cytoskeleton adjustments

Yu Du, Carolina Montoya, Santiago Orrego, Xi Wei, Junqi Ling, Peter I. Lelkes, Maobin Yang

Cell Prolif. 2019 Nov; 52(6): e12676. Published online 2019 Aug 19. doi: 10.1111/cpr.12676

PMCID:: PMC6869304

Abstract Article PDF–1.6M

Select item 596373418.

α-Actinin Anchors PSD-95 at Postsynaptic Sites

Lucas Matt, Karam Kim, Anne E. Hergarden, Tommaso Patriarchi, Zulfiqar A. Malik, Deborah K. Park, Dhrubajyoti Chowdhury, Olivia R. Buonarati, Peter B. Henderson, Çiğdem Gökçek Saraç, Yonghong Zhang, Durga Mohapatra, Mary C. Horne, James B. Ames, Johannes W. Hell

Neuron. Author manuscript; available in PMC 2019 Mar 7.

Published in final edited form as: Neuron. 2018 Mar 7; 97(5): 1094–1109.e9. Published online 2018 Feb 8. doi: 10.1016/j.neuron.2018.01.036