PMC Links for Gene (Select 8711) - PMC

Select item 97036321.

The noncatalytic regions of the tyrosine kinase Tnk1 are important for activity and substrate specificity

Sultan Ahmed, W. Todd Miller

J Biol Chem. 2022 Dec; 298(12): 102664. Published online 2022 Nov 2. doi: 10.1016/j.jbc.2022.102664

PMCID:: PMC9703632

Select item 74790972.

Thirty-Eight-Negative Kinase 1 Is a Mediator of Acute Kidney Injury in Experimental and Clinical Traumatic Hemorrhagic Shock

Rebecca Halbgebauer, Ebru Karasu, Christian K. Braun, Annette Palmer, Sonja Braumüller, Anke Schultze, Fabian Schäfer, Sarah Bückle, Alica Eigner, Ulrich Wachter, Peter Radermacher, Ranillo R. G. Resuello, Joel V. Tuplano, Kristina Nilsson Ekdahl, Bo Nilsson, Milena Armacki, Alexander Kleger, Thomas Seufferlein, Miriam Kalbitz, Florian Gebhard, John D. Lambris, Martijn van Griensven, Markus Huber-Lang

Front Immunol. 2020; 11: 2081. Published online 2020 Aug 26. doi: 10.3389/fimmu.2020.02081

PMCID:: PMC7479097

Abstract Article PDF–2.3M

Select item 31379033.

High-throughput RNAi screening identifies a role for TNK1 in growth and survival of pancreatic cancer cells

Meredith C. Henderson, Irma M. Gonzales, Shilpi Arora, Ashish Choudhary, Jeffrey M. Trent, Daniel D. Von Hoff, Spyro Mousses, David O. Azorsa

Mol Cancer Res. Author manuscript; available in PMC 2012 Jun 1.

Published in final edited form as: Mol Cancer Res. 2011 Jun; 9(6): 724–732. Published online 2011 May 2. doi: 10.1158/1541-7786.MCR-10-0436

PMCID:: PMC3137903

Abstract Article PDF–988K

Select item 84297284.

TNK1 is a ubiquitin-binding and 14-3-3-regulated kinase that can be targeted to block tumor growth

Tsz-Yin Chan, Christina M. Egbert, Julia E. Maxson, Adam Siddiqui, Logan J. Larsen, Kristina Kohler, Eranga Roshan Balasooriya, Katie L. Pennington, Tsz-Ming Tsang, Madison Frey, Erik J. Soderblom, Huimin Geng, Markus Müschen, Tetyana V. Forostyan, Savannah Free, Gaelle Mercenne, Courtney J. Banks, Jonard Valdoz, Clifford J. Whatcott, Jason M. Foulks, David J. Bearss, Thomas O’Hare, David C. S. Huang, Kenneth A. Christensen, James Moody, Steven L. Warner, Jeffrey W. Tyner, Joshua L. Andersen

Nat Commun. 2021; 12: 5337. Published online 2021 Sep 9. doi: 10.1038/s41467-021-25622-3

PMCID:: PMC8429728

Abstract Article PDF–3.5M

Select item 62054005.

Thirty-eight-negative kinase 1 mediates trauma-induced intestinal injury and multi-organ failure

Milena Armacki, Anna Katharina Trugenberger, Ann K. Ellwanger, Tim Eiseler, Christiane Schwerdt, Lucas Bettac, Dominik Langgartner, Ninel Azoitei, Rebecca Halbgebauer, Rüdiger Groß, Tabea Barth, André Lechel, Benjamin M. Walter, Johann M. Kraus, Christoph Wiegreffe, Johannes Grimm, Annika Scheffold, Marlon R. Schneider, Kenneth Peuker, Sebastian Zeißig, Stefan Britsch, Stefan Rose-John, Sabine Vettorazzi, Eckhart Wolf, Andrea Tannapfel, Konrad Steinestel, Stefan O. Reber, Paul Walther, Hans A. Kestler, Peter Radermacher, Thomas F.E. Barth, Markus Huber-Lang, Alexander Kleger, Thomas Seufferlein

J Clin Invest. 2018 Nov 1; 128(11): 5056–5072. Published online 2018 Oct 15. doi: 10.1172/JCI97912

PMCID:: PMC6205400

Abstract Article PDF–33M

Select item 39187916.

Novel antiviral host factor, TNK1, regulates IFN signaling through serine phosphorylation of STAT1

Ee Lyn Ooi, Stephanie T. Chan, Noell E. Cho, Courtney Wilkins, Jessica Woodward, Meng Li, Ushio Kikkawa, Timothy Tellinghuisen, Michael Gale, Jr., Takeshi Saito

Proc Natl Acad Sci U S A. 2014 Feb 4; 111(5): 1909–1914. Published online 2014 Jan 21. doi: 10.1073/pnas.1314268111

PMCID:: PMC3918791

Abstract Article PDF–1019K

Select item 28411327.

Assessment of Alzheimer’s disease case–control associations using family-based methods

Brit-Maren M. Schjeide, Matthew B. McQueen, Kristina Mullin, Jason DiVito, Meghan F. Hogan, Michele Parkinson, Basavaraj Hooli, Christoph Lange, Deborah Blacker, Rudolph E. Tanzi, Lars Bertram

Neurogenetics. Author manuscript; available in PMC 2010 Mar 17.

Published in final edited form as: Neurogenetics. 2009 Feb; 10(1): 19–25. Published online 2008 Oct 2. doi: 10.1007/s10048-008-0151-3

PMCID:: PMC2841132

Abstract Article PDF–85K

Select item 28885898.

Intermediate Phenotypes Identify Divergent Pathways to Alzheimer's Disease

Joshua M. Shulman, Lori B. Chibnik, Cristin Aubin, Julie A. Schneider, David A. Bennett, Philip L. De Jager

PLoS One. 2010; 5(6): e11244. Published online 2010 Jun 21. doi: 10.1371/journal.pone.0011244

PMCID:: PMC2888589

Abstract Article PDF–138K

Select item 29084699.

Association of CR1, CLU and PICALM with Alzheimer's disease in a cohort of clinically characterized and neuropathologically verified individuals

Jason J. Corneveaux, Amanda J. Myers, April N. Allen, Jeremy J. Pruzin, Manuel Ramirez, Anzhelika Engel, Michael A. Nalls, Kewei Chen, Wendy Lee, Kendria Chewning, Stephen E. Villa, Hunsar B. Meechoovet, Jill D. Gerber, Danielle Frost, Hollie L. Benson, Sean O'Reilly, Lori B. Chibnik, Joshua M. Shulman, Andrew B. Singleton, David W. Craig, Kendall R. Van Keuren-Jensen, Travis Dunckley, David A. Bennett, Philip L. De Jager, Christopher Heward, John Hardy, Eric M. Reiman, Matthew J. Huentelman

Hum Mol Genet. 2010 Aug 15; 19(16): 3295–3301. Published online 2010 Jun 9. doi: 10.1093/hmg/ddq221

PMCID:: PMC2908469

Abstract Article PDF–101K

Select item 389478610.

Quantitative Analysis of Hsp90-Client Interactions Reveals Principles of Substrate Recognition

Mikko Taipale, Irina Krykbaeva, Martina Koeva, Can Kayatekin, Kenneth D. Westover, Georgios I. Karras, Susan Lindquist

Cell. Author manuscript; available in PMC 2014 Jan 17.

Published in final edited form as: Cell. 2012 Aug 31; 150(5): 987–1001. doi: 10.1016/j.cell.2012.06.047

PMCID:: PMC3894786

Abstract Article PDF–5.0M

Select item 1007290611.

Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity

Martin Golkowski, Andrea Lius, Tanmay Sapre, Ho-Tak Lau, Taylor Moreno, Dustin J. Maly, Shao-En Ong

Mol Cell. Author manuscript; available in PMC 2023 Apr 4.

Published in final edited form as: Mol Cell. 2023 Mar 2; 83(5): 803–818.e8. Published online 2023 Feb 2. doi: 10.1016/j.molcel.2023.01.015

PMCID:: PMC10072906

Abstract Article PDF–4.2M

Select item 742732712.

Kinase Interaction Network Expands Functional and Disease Roles of Human Kinases

Marija Buljan, Rodolfo Ciuffa, Audrey van Drogen, Anton Vichalkovski, Martin Mehnert, George Rosenberger, Sohyon Lee, Markku Varjosalo, Lucia Espona Pernas, Vincent Spegg, Berend Snijder, Ruedi Aebersold, Matthias Gstaiger

Mol Cell. 2020 Aug 6; 79(3): 504–520.e9. doi: 10.1016/j.molcel.2020.07.001

PMCID:: PMC7427327

Abstract Article

Select item 135612913.

Diversification of transcriptional modulation: Large-scale identification and characterization of putative alternative promoters of human genes

Kouichi Kimura, Ai Wakamatsu, Yutaka Suzuki, Toshio Ota, Tetsuo Nishikawa, Riu Yamashita, Jun-ichi Yamamoto, Mitsuo Sekine, Katsuki Tsuritani, Hiroyuki Wakaguri, Shizuko Ishii, Tomoyasu Sugiyama, Kaoru Saito, Yuko Isono, Ryotaro Irie, Norihiro Kushida, Takahiro Yoneyama, Rie Otsuka, Katsuhiro Kanda, Takahide Yokoi, Hiroshi Kondo, Masako Wagatsuma, Katsuji Murakawa, Shinichi Ishida, Tadashi Ishibashi, Asako Takahashi-Fujii, Tomoo Tanase, Keiichi Nagai, Hisashi Kikuchi, Kenta Nakai, Takao Isogai, Sumio Sugano

Genome Res. 2006 Jan; 16(1): 55–65. doi: 10.1101/gr.4039406

PMCID:: PMC1356129

Abstract Article PDF–438K

Select item 716998314.

A reference map of the human binary protein interactome

Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood

Nature. Author manuscript; available in PMC 2020 Oct 8.

Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x

PMCID:: PMC7169983

Abstract Article PDF–5.4M

Select item 816503015.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011