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Items: 1 to 20 of 42

1.
Numb-like (NumbL) downregulation increases tumorigenicity, cancer stem cell-like properties and resistance to chemotherapy
José M. García-Heredia, Eva M. Verdugo Sivianes, Antonio Lucena-Cacace, Sonia Molina-Pinelo, Amancio Carnero
Oncotarget. 2016 Sep 27; 7(39): 63611–63628. Published online 2016 Aug 23. doi: 10.18632/oncotarget.11553
PMCID:
PMC5325389
AbstractArticlePDF–11M
2.
REGULATION OF LUNG CANCER METASTASIS BY Klf4-Numb-like SIGNALING
Valentina Vaira, Alice Faversani, Nina M. Martin, David S. Garlick, Stefano Ferrero, Mario Nosotti, Joseph L. Kissil, Silvano Bosari, Dario C. Altieri
Cancer Res. Author manuscript; available in PMC 2014 Apr 15.
Published in final edited form as: Cancer Res. 2013 Apr 15; 73(8): 2695–2705. Published online 2013 Feb 25. doi: 10.1158/0008-5472.CAN-12-4232
PMCID:
PMC3695627
AbstractArticlePDF–3.9M
3.
SLC8A1 antisense RNA 1 suppresses papillary thyroid cancer malignant progression via the FUS RNA binding protein (FUS)/NUMB like endocytic adaptor protein (Numbl) axis
Yunchao Xin, Xiaoling Shang, Xiaoran Sun, Guogang Xu, Yachao Liu, Yanbin Liu
Bioengineered. 2022; 13(5): 12572–12582. Published online 2022 May 21. doi: 10.1080/21655979.2022.2073125
PMCID:
PMC9275960
AbstractArticlePDF–4.2M
4.
Up-regulation of microRNA let-7c by quercetin inhibits pancreatic cancer progression by activation of Numbl
Clifford C. Nwaeburu, Natalie Bauer, Zhefu Zhao, Alia Abukiwan, Jury Gladkich, Axel Benner, Ingrid Herr
Oncotarget. 2016 Sep 6; 7(36): 58367–58380. Published online 2016 Aug 8. doi: 10.18632/oncotarget.11122
PMCID:
PMC5295436
AbstractArticlePDF–6.9M
5.
Numbl inhibits glioma cell migration and invasion by suppressing TRAF5-mediated NF-κB activation
Tao Tao, Chun Cheng, Yuhong Ji, Guangfei Xu, Jianguo Zhang, Li Zhang, Aiguo Shen
Mol Biol Cell. 2012 Jul 15; 23(14): 2635–2644. doi: 10.1091/mbc.E11-09-0805
PMCID:
PMC3395653
AbstractArticlePDF–4.5M
6.
The γ-secretase-generated intracellular domain of β-amyloid precursor protein binds Numb and inhibits Notch signaling
Roberta Roncarati, Nenad Šestan, Meir H. Scheinfeld, Bridget E. Berechid, Peter A. Lopez, Olimpia Meucci, Jane C. McGlade, Pasko Rakic, Luciano D'Adamio
Proc Natl Acad Sci U S A. 2002 May 14; 99(10): 7102–7107. doi: 10.1073/pnas.102192599
PMCID:
PMC124535
AbstractArticlePDF–410K
7.
A protein-binding domain, EH, identified in the receptor tyrosine kinase substrate Eps15 and conserved in evolution.
W T Wong, C Schumacher, A E Salcini, A Romano, P Castagnino, P G Pelicci, P Di Fiore
Proc Natl Acad Sci U S A. 1995 Oct 10; 92(21): 9530–9534. doi: 10.1073/pnas.92.21.9530
PMCID:
PMC40835
SummaryPage BrowsePDF–1.5M
8.
NUMBL Interacts with TAK1, TRAF6 and NEMO to Negatively Regulate NF-κB Signaling During Osteoclastogenesis
Gaurav Swarnkar, Tim Hung-Po Chen, Manoj Arra, Amjad M. Nasir, Gabriel Mbalaviele, Yousef Abu-Amer
Sci Rep. 2017; 7: 12600. Published online 2017 Oct 3. doi: 10.1038/s41598-017-12707-7
PMCID:
PMC5626749
AbstractArticlePDF–3.8M
9.
Binding specificity and in vivo targets of the EH domain, a novel protein–protein interaction module
Anna Elisabetta Salcini, Stefano Confalonieri, Margherita Doria, Elisa Santolini, Elena Tassi, Olga Minenkova, Gianni Cesareni, Pier Giuseppe Pelicci, Pier Paolo Di Fiore
Genes Dev. 1997 Sep 1; 11(17): 2239–2249. doi: 10.1101/gad.11.17.2239
PMCID:
PMC275390
AbstractArticlePDF–1.7M
10.
Adaptor proteins NUMB and NUMBL promote cell cycle withdrawal by targeting ERBB2 for degradation
Maretoshi Hirai, Yoh Arita, C. Jane McGlade, Kuo-Fen Lee, Ju Chen, Sylvia M. Evans
J Clin Invest. 2017 Feb 1; 127(2): 569–582. Published online 2017 Jan 9. doi: 10.1172/JCI91081
PMCID:
PMC5272190
AbstractArticlePDF–6.4M
11.
Proteomic analysis reveals novel ligands and substrates for LNX1 E3 ubiquitin ligase
Joan A. Lenihan, Orthis Saha, Paul W. Young
PLoS One. 2017; 12(11): e0187352. Published online 2017 Nov 9. doi: 10.1371/journal.pone.0187352
PMCID:
PMC5679597
AbstractArticlePDF–10M
12.
PTPRA Phosphatase Regulates GDNF-Dependent RET Signaling and Inhibits the RET Mutant MEN2A Oncogenic Potential
Leena Yadav, Elina Pietilä, Tiina Öhman, Xiaonan Liu, Arun K. Mahato, Yulia Sidorova, Kaisa Lehti, Mart Saarma, Markku Varjosalo
iScience. 2020 Feb 21; 23(2): 100871. Published online 2020 Jan 31. doi: 10.1016/j.isci.2020.100871
PMCID:
PMC7021549
AbstractArticlePDF–8.1M
13.
LZTR1 is a regulator of RAS ubiquitination and signaling
Johannes W. Bigenzahn, Giovanna M. Collu, Felix Kartnig, Melanie Pieraks, Gregory I. Vladimer, Leonhard X. Heinz, Vitaly Sedlyarov, Fiorella Schischlik, Astrid Fauster, Manuele Rebsamen, Katja Parapatics, Vincent A. Blomen, André C. Müller, Georg E. Winter, Robert Kralovics, Thijn R. Brummelkamp, Marek Mlodzik, Giulio Superti-Furga
Science. Author manuscript; available in PMC 2019 Oct 15.
Published in final edited form as: Science. 2018 Dec 7; 362(6419): 1171–1177. Published online 2018 Nov 15. doi: 10.1126/science.aap8210
PMCID:
PMC6794158
AbstractArticlePDF–1.9M
14.
Identification of phagocytosis regulators using magnetic genome-wide CRISPR screens
Michael S. Haney, Christopher J. Bohlen, David W Morgens, James A. Ousey, Amira A. Barkal, C. Kimberly Tsui, Braeden Ego, Roni Levin, Roarke Kamber, Hannah Collins, Andrew Tucker, Amy Li, Daan Vorselen, Lorenzo Labitigan, Emily Crane, Evan Boyle, Lihua Jiang, Joanne Chan, Esther Rincón, William J. Greenleaf, Billy Li, Michael P. Snyder, Irving L. Weissman, Julie A. Theriot, Sean R. Collins, Ben A. Barres, Michael C. Bassik
Nat Genet. Author manuscript; available in PMC 2019 Sep 3.
Published in final edited form as: Nat Genet. 2018 Dec; 50(12): 1716–1727. Published online 2018 Nov 5. doi: 10.1038/s41588-018-0254-1
PMCID:
PMC6719718
AbstractArticlePDF–1.3M
15.
BioID Performed on Golgi Enriched Fractions Identify C10orf76 as a GBF1 Binding Protein Essential for Golgi Maintenance and Secretion
Calvin J. Chan, Roberta Le, Kaylan Burns, Khadra Ahmed, Etienne Coyaud, Estelle M. N. Laurent, Brian Raught, Paul Melançon
Mol Cell Proteomics. 2019 Nov; 18(11): 2285–2297. Published online 2019 Sep 13. doi: 10.1074/mcp.RA119.001645
PMCID:
PMC6823846
AbstractArticlePDF–2.2M
16.
A conserved acetylation switch enables pharmacological control of tubby-like protein stability
Evan M. Kerek, Kevin H. Yoon, Shu Y. Luo, Jerry Chen, Robert Valencia, Olivier Julien, Andrew J. Waskiewicz, Basil P. Hubbard
J Biol Chem. 2021 Jan-Jun; 296: 100073. Published online 2020 Nov 23. doi: 10.1074/jbc.RA120.015839
PMCID:
PMC7948452
AbstractArticlePDF–3.6M
17.
Global analysis of host-pathogen interactions that regulate early stage HIV-1 replication
Renate König, Yingyao Zhou, Daniel Elleder, Tracy L. Diamond, Ghislain M.C. Bonamy, Jeffrey T. Irelan, Chih-yuan Chiang, Buu P. Tu, Paul D. De Jesus, Caroline E. Lilley, Shannon Seidel, Amanda M. Opaluch, Jeremy S. Caldwell, Matthew D. Weitzman, Kelli L. Kuhen, Sourav Bandyopadhyay, Trey Ideker, Anthony P. Orth, Loren J. Miraglia, Frederic D. Bushman, John A. Young, Sumit K. Chanda
Cell. Author manuscript; available in PMC 2009 Oct 3.
Published in final edited form as: Cell. 2008 Oct 3; 135(1): 49–60. doi: 10.1016/j.cell.2008.07.032
PMCID:
PMC2628946
AbstractArticlePDF–3.4M
18.
Proximity labelling identifies pro-migratory endocytic recycling cargo and machinery of the Rab4 and Rab11 families
Beverley Wilson, Chloe Flett, Jakub Gemperle, Craig Lawless, Matthew Hartshorn, Eleanor Hinde, Tess Harrison, Megan Chastney, Sarah Taylor, Jennifer Allen, Jim C. Norman, Thomas Zacharchenko, Patrick T. Caswell
J Cell Sci. 2023 Jun 15; 136(12): jcs260468. Published online 2023 Jun 23. doi: 10.1242/jcs.260468
PMCID:
PMC10323252
AbstractArticle
19.
Cooperative polarization of MCAM/CD146 and ERM family proteins in melanoma
Suzannah G. Miller, Maria Hoh, Christopher C. Ebmeier, Jian Wei Tay, Natalie G. Ahn
Mol Biol Cell. 2024 Mar 1; 35(3): ar31. Published online 2024 Jan 29. doi: 10.1091/mbc.E23-06-0255
PMCID:
PMC10916866
AbstractArticlePDF–4.7M
20.
BCAR1 promotes proliferation and cell growth in lung adenocarcinoma via upregulation of POLR2A
Chun‐guo Mao, Sha‐sha Jiang, Cheng Shen, Tan Long, Hua Jin, Qun‐You Tan, Bo Deng
Thorac Cancer. 2020 Nov; 11(11): 3326–3336. Published online 2020 Oct 1. doi: 10.1111/1759-7714.13676
PMCID:
PMC7606008
AbstractArticlePDF–2.5M

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