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Select item 109161891.

Integration analysis of lncRNA and mRNA expression data identifies DOCK4 as a potential biomarker for elderly osteoporosis

Chengai Wu, Chao Wang, Bin Xiao, Shan Li, Yueyang Sheng, Qianqian Wang, Jianfeng Tao, Yanzhuo Zhang, Xu Jiang

BMC Med Genomics. 2024; 17: 70. Published online 2024 Mar 5. doi: 10.1186/s12920-024-01837-3

PMCID:: PMC10916189

Abstract Article PDF–5.6M

Select item 73550362.

Up-regulated cytotrophoblast DOCK4 contributes to over-invasion in placenta accreta spectrum

Leah McNally, Yan Zhou, Joshua F. Robinson, Guangfeng Zhao, Lee-may Chen, Hao Chen, M. Yvonne Kim, Mirhan Kapidzic, Matthew Gormley, Roberta Hannibal, Susan J. Fisher

Proc Natl Acad Sci U S A. 2020 Jul 7; 117(27): 15852–15861. Published online 2020 Jun 23. doi: 10.1073/pnas.1920776117

PMCID:: PMC7355036

Abstract Article PDF–2.8M

Select item 47746463.

Molecular association between β-catenin degradation complex and Rac guanine exchange factor DOCK4 is essential for Wnt/β-catenin signaling

G Upadhyay, W Goessling, TE North, R Xavier, LI Zon, V Yajnik

Oncogene. Author manuscript; available in PMC 2016 Mar 2.

Published in final edited form as: Oncogene. 2008 Oct 2; 27(44): 5845–5855. Published online 2008 Jul 21. doi: 10.1038/onc.2008.202

PMCID:: PMC4774646

Abstract Article PDF–1.3M

Select item 43181424.

TGF-β/Smad signaling through DOCK4 facilitates lung adenocarcinoma metastasis

Jia-Ray Yu, Yilin Tai, Ying Jin, Molly C. Hammell, J. Erby Wilkinson, Jae-Seok Roe, Christopher R. Vakoc, Linda Van Aelst

Genes Dev. 2015 Feb 1; 29(3): 250–261. doi: 10.1101/gad.248963.114

PMCID:: PMC4318142

Abstract Article PDF–1.3M

Select item 31370925.

Aberrant Epigenetic and Genetic Marks Are Seen in Myelodysplastic Leukocytes and Reveal Dock4 as a Candidate Pathogenic Gene on Chromosome 7q

Li Zhou, Joanna Opalinska, Davendra Sohal, Yiting Yu, Yongkai Mo, Tushar Bhagat, Omar Abdel-Wahab, Melissa Fazzari, Maria Figueroa, Cristina Alencar, Jinghang Zhang, Suman Kambhampati, Simrit Parmar, Sangeeta Nischal, Christoph Hueck, Masako Suzuki, Ellen Freidman, Andrea Pellagatti, Jacqueline Boultwood, Ulrich Steidl, Yogen Sauthararajah, Vijay Yajnik, Christine Mcmahon, Steven D. Gore, Leonidas C. Platanias, Ross Levine, Ari Melnick, Amittha Wickrema, John M. Greally, Amit Verma

J Biol Chem. 2011 Jul 15; 286(28): 25211–25223. Published online 2011 Apr 30. doi: 10.1074/jbc.M111.235028

PMCID:: PMC3137092

Abstract Article PDF–3.8M

Select item 81029836.

USP36-Mediated Deubiquitination of DOCK4 Contributes to the Diabetic Renal Tubular Epithelial Cell Injury via Wnt/β-Catenin Signaling Pathway

Suwei Zhu, Shaoshuai Hou, Yao Lu, Wei Sheng, Zhengguo Cui, Tianyi Dong, Hong Feng, Qiang Wan

Front Cell Dev Biol. 2021; 9: 638477. Published online 2021 Apr 23. doi: 10.3389/fcell.2021.638477

PMCID:: PMC8102983

Abstract Article PDF–3.6M

Select item 39559137.

Family-based association study of ZNF533, DOCK4 and IMMP2L gene polymorphisms linked to autism in a northeastern Chinese Han population

Shuang Liang, Xue-lai Wang, Ming-yang Zou, Han Wang, Xue Zhou, Cai-hong Sun, Wei Xia, Li-jie Wu, Takashi X. Fujisawa, Akemi Tomoda

J Zhejiang Univ Sci B. 2014 Mar; 15(3): 264–271. doi: 10.1631/jzus.B1300133

PMCID:: PMC3955913

Abstract Article PDF–390K

Select item 29410178.

Characterization of a Family with Rare Deletions in CNTNAP5 and DOCK4 Suggests Novel Risk Loci for Autism and Dyslexia

Alistair T. Pagnamenta, Elena Bacchelli, Maretha V. de Jonge, Ghazala Mirza, Thomas S. Scerri, Fiorella Minopoli, Andreas Chiocchetti, Kerstin U. Ludwig, Per Hoffmann, Silvia Paracchini, Ernesto Lowy, Denise H. Harold, Jade A. Chapman, Sabine M. Klauck, Fritz Poustka, Renske H. Houben, Wouter G. Staal, Roel A. Ophoff, Michael C. O'Donovan, Julie Williams, Markus M. Nöthen, Gerd Schulte-Körne, Panos Deloukas, Jiannis Ragoussis, Anthony J. Bailey, Elena Maestrini, Anthony P. Monaco, International Molecular Genetic Study Of Autism Consortium

Biol Psychiatry. 2010 Aug 15; 68(4): 320–328. doi: 10.1016/j.biopsych.2010.02.002

PMCID:: PMC2941017

Abstract Article

Select item 46555819.

Reduced DOCK4 expression leads to erythroid dysplasia in myelodysplastic syndromes

Sriram Sundaravel, Ryan Duggan, Tushar Bhagat, David L. Ebenezer, Hui Liu, Yiting Yu, Matthias Bartenstein, Madhu Unnikrishnan, Subhradip Karmakar, Ting-Chun Liu, Ingrid Torregroza, Thomas Quenon, John Anastasi, Kathy L. McGraw, Andrea Pellagatti, Jacqueline Boultwood, Vijay Yajnik, Andrew Artz, Michelle M. Le Beau, Ulrich Steidl, Alan F. List, Todd Evans, Amit Verma, Amittha Wickrema

Proc Natl Acad Sci U S A. 2015 Nov 17; 112(46): E6359–E6368. Published online 2015 Nov 2. doi: 10.1073/pnas.1516394112

PMCID:: PMC4655581

Abstract Article PDF–1.9M

Select item 663134610.

SR-B1 Drives Endothelial Cell LDL Transcytosis via DOCK4 to Promote Atherosclerosis

Linzhang Huang, Ken L. Chambliss, Xiaofei Gao, Ivan S. Yuhanna, Erica Behling-Kelly, Sonia Bergaya, Mohamed Ahmed, Peter Michaely, Kate Luby-Phelps, Anza Darehshouri, Lin Xu, Edward A. Fisher, Woo-Ping Ge, Chieko Mineo, Philip W. Shaul

Nature. Author manuscript; available in PMC 2019 Oct 24.

Published in final edited form as: Nature. 2019 May; 569(7757): 565–569. Published online 2019 Apr 24. doi: 10.1038/s41586-019-1140-4

PMCID:: PMC6631346

Abstract Article PDF–7.2M

Select item 450700711.

A Rac/Cdc42 exchange factor complex promotes formation of lateral filopodia and blood vessel lumen morphogenesis

Sabu Abraham, Margherita Scarcia, Richard D. Bagshaw, Kathryn McMahon, Gary Grant, Tracey Harvey, Maggie Yeo, Filomena O.G. Esteves, Helene H. Thygesen, Pamela F. Jones, Valerie Speirs, Andrew M. Hanby, Peter J. Selby, Mihaela Lorger, T. Neil Dear, Tony Pawson, Christopher J. Marshall, Georgia Mavria

Nat Commun. 2015; 6: 7286. Published online 2015 Jul 1. doi: 10.1038/ncomms8286

PMCID:: PMC4507007

Abstract Article PDF–4.6M

Select item 272573212.

Cell Migration Is Regulated by Platelet-Derived Growth Factor Receptor Endocytosis

Kenji Kawada, Geeta Upadhyay, Sébastien Ferandon, Sailajah Janarthanan, Matthew Hall, Jean-Pierre Vilardaga, Vijay Yajnik

Mol Cell Biol. 2009 Aug; 29(16): 4508–4518. Published online 2009 Jun 15. doi: 10.1128/MCB.00015-09

PMCID:: PMC2725732

Abstract Article PDF–2.9M

Select item 370770113.

The Atypical Guanine Nucleotide Exchange Factor Dock4 Regulates Neurite Differentiation through Modulation of Rac1 GTPase and Actin Dynamics

Yangui Xiao, Yinghui Peng, Jun Wan, Genyun Tang, Yuewen Chen, Jing Tang, Wen-Cai Ye, Nancy Y. Ip, Lei Shi

J Biol Chem. 2013 Jul 5; 288(27): 20034–20045. Published online 2013 May 17. doi: 10.1074/jbc.M113.458612

PMCID:: PMC3707701

Abstract Article PDF–4.2M

Select item 278255414.

Analysis of DNA Copy Number Alterations in Ovarian Serous Tumors Identifies New Molecular Genetic Changes in Low-grade and High-grade Carcinomas

Kuan-Ting Kuo, Bin Guan, Yuanjian Feng, Tsui-Lien Mao, Xu Chen, Natini Jinawath, Yue Wang, Robert J. Kurman, Ie-Ming Shih, Tian-Li Wang

Cancer Res. Author manuscript; available in PMC 2010 May 1.

Published in final edited form as: Cancer Res. 2009 May 1; 69(9): 4036–4042. Published online 2009 Apr 21. doi: 10.1158/0008-5472.CAN-08-3913

Correction in:: volume 69 on page 5267

PMCID:: PMC2782554

Abstract Article PDF–2.0M

Select item 376042015.

Genome-wide association study indicates variants associated with insulin signaling and inflammation mediate lipoprotein responses to fenofibrate

Alexis C. Frazier-Wood, Stella Aslibekyan, Ingrid B. Borecki, Paul N. Hopkins, Chao-Qiang Lai, Jose M. Ordovas, Robert J. Straka, Hemant K. Tiwari, Donna K. Arnett

Pharmacogenet Genomics. Author manuscript; available in PMC 2013 Oct 1.

Published in final edited form as: Pharmacogenet Genomics. 2012 Oct; 22(10): 750–757. doi: 10.1097/FPC.0b013e328357f6af

PMCID:: PMC3760420

Abstract Article PDF–723K

Select item 328173716.

Bone Morphogenetic Protein 4 Promotes Vascular Smooth Muscle Contractility by Activating MicroRNA-21 (miR-21), which Down-regulates Expression of Family of Dedicator of Cytokinesis (DOCK) Proteins

Hara Kang, Brandi N. Davis-Dusenbery, Peter H. Nguyen, Ashish Lal, Judy Lieberman, Linda Van Aelst, Giorgio Lagna, Akiko Hata

J Biol Chem. 2012 Feb 3; 287(6): 3976–3986. Published online 2011 Dec 9. doi: 10.1074/jbc.M111.303156

PMCID:: PMC3281737

Abstract Article PDF–2.2M

Select item 292263717.

Ephexin4 and EphA2 mediate cell migration through a RhoG-dependent mechanism

Nao Hiramoto-Yamaki, Shingo Takeuchi, Shuhei Ueda, Kohei Harada, Satoshi Fujimoto, Manabu Negishi, Hironori Katoh

J Cell Biol. 2010 Aug 9; 190(3): 461–477. doi: 10.1083/jcb.201005141

PMCID:: PMC2922637

Abstract Article PDF–4.0M

Select item 329847318.

Effects of partner proteins on BCA2 RING ligase activity

Stephanie Bacopulos, Yutaka Amemiya, Wenyi Yang, Judit Zubovits, Angelika Burger, Martin Yaffe, Arun K Seth

BMC Cancer. 2012; 12: 63. Published online 2012 Feb 8. doi: 10.1186/1471-2407-12-63

PMCID:: PMC3298473

Abstract Article PDF–7.3M

Select item 323472219.

The Arf Family GTPase Arl4A Complexes with ELMO Proteins to Promote Actin Cytoskeleton Remodeling and Reveals a Versatile Ras-binding Domain in the ELMO Proteins Family

Manishha Patel, Tsai-Chen Chiang, Viviane Tran, Fang-Jen S. Lee, Jean-François Côté

J Biol Chem. 2011 Nov 11; 286(45): 38969–38979. Published online 2011 Sep 19. doi: 10.1074/jbc.M111.274191

PMCID:: PMC3234722

Abstract Article PDF–2.5M

Select item 293473920.

High-density SNP association study and copy number variation analysis of the AUTS1 and AUTS5 loci implicate the IMMP2L–DOCK4 gene region in autism susceptibility

E Maestrini, A T Pagnamenta, J A Lamb, E Bacchelli, N H Sykes, I Sousa, C Toma, G Barnby, H Butler, L Winchester, T S Scerri, F Minopoli, J Reichert, G Cai, J D Buxbaum, O Korvatska, G D Schellenberg, G Dawson, A de Bildt, R B Minderaa, E J Mulder, A P Morris, A J Bailey, A P Monaco, IMGSAC

Mol Psychiatry. 2010 Sep; 15(9): 954–968. Published online 2009 Apr 28. doi: 10.1038/mp.2009.34

PMCID:: PMC2934739

Abstract Article PDF–376K

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