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Select item 46176061.

A non-proteolytic role for ubiquitin in deadenylation of MHC-I mRNA by the RNA-binding E3-ligase MEX-3C

Florencia Cano, Radu Rapiteanu, G. Sebastiaan Winkler, Paul J. Lehner

Nat Commun. 2015; 6: 8670. Published online 2015 Oct 16. doi: 10.1038/ncomms9670

PMCID:: PMC4617606

Article PDF–1.6M

Select item 33473352.

A Protein Array Screen for Kaposi's Sarcoma-Associated Herpesvirus LANA Interactors Links LANA to TIP60, PP2A Activity, and Telomere Shortening

Meir Shamay, Jianyong Liu, Renfeng Li, Gangling Liao, Li Shen, Melanie Greenway, Shaohui Hu, Jian Zhu, Zhi Xie, Richard F. Ambinder, Jiang Qian, Heng Zhu, S. Diane Hayward

J Virol. 2012 May; 86(9): 5179–5191. doi: 10.1128/JVI.00169-12

PMCID:: PMC3347335

Article PDF–1.1M

Select item 24305963.

Molecular Genetics of Successful Smoking Cessation: Convergent Genome-Wide Association Study Results

George R. Uhl, Qing-Rong Liu, Tomas Drgon, Catherine Johnson, Donna Walther, Jed E. Rose, Sean P. David, Ray Niaura, Caryn Lerman

Arch Gen Psychiatry. Author manuscript; available in PMC 2008 Jun 17.

Published in final edited form as: Arch Gen Psychiatry. 2008 Jun; 65(6): 683–693. doi: 10.1001/archpsyc.65.6.683

PMCID:: PMC2430596

Article PDF–1.0M

Select item 1336174.

Functional Proteomic Analysis of Human Nucleolus

Alexander Scherl, Yohann Couté, Catherine Déon, Aleth Callé, Karine Kindbeiter, Jean-Charles Sanchez, Anna Greco, Denis Hochstrasser, Jean-Jacques Diaz

Mol Biol Cell. 2002 Nov; 13(11): 4100–4109. doi: 10.1091/mbc.E02-05-0271

PMCID:: PMC133617

Article PDF–369K

Select item 45873265.

BioID-based Identification of Skp Cullin F-box (SCF)^β-TrCP1/2 E3 Ligase Substrates

Etienne Coyaud, Monika Mis, Estelle M. N. Laurent, Wade H. Dunham, Amber L. Couzens, Melanie Robitaille, Anne-Claude Gingras, Stephane Angers, Brian Raught

Mol Cell Proteomics. 2015 Jul; 14(7): 1781–1795. Published online 2015 Apr 21. doi: 10.1074/mcp.M114.045658

PMCID:: PMC4587326

Article PDF–3.7M

Select item 51776016.

FOXA1 Directs H3K4 Monomethylation at Enhancers via Recruitment of the Methyltransferase MLL3

Kamila M. Jozwik, Igor Chernukhin, Aurelien A. Serandour, Sankari Nagarajan, Jason S. Carroll

Cell Rep. 2016 Dec 6; 17(10): 2715–2723. Published online 2016 Dec 6. doi: 10.1016/j.celrep.2016.11.028

PMCID:: PMC5177601

Article PDF–2.9M

Select item 80177207.

SLFN11 promotes CDT1 degradation by CUL4 in response to replicative DNA damage, while its absence leads to synthetic lethality with ATR/CHK1 inhibitors

Ukhyun Jo, Yasuhisa Murai, Sirisha Chakka, Lu Chen, Ken Cheng, Junko Murai, Liton Kumar Saha, Lisa M. Miller Jenkins, Yves Pommier

Proc Natl Acad Sci U S A. 2021 Feb 9; 118(6): e2015654118. Published online 2021 Feb 3. doi: 10.1073/pnas.2015654118

PMCID:: PMC8017720

Article PDF–1.9M

Select item 58495348.

Genome-wide CRISPR-Cas9 screen identifies leukemia-specific dependence on a pre-mRNA metabolic pathway regulated by DCPS

Takuji Yamauchi, Takeshi Masuda, Matthew C. Canver, Michael Seiler, Yuichiro Semba, Mohammad Shboul, Mohammed Al-Raqad, Manami Maeda, Vivien A. C. Schoonenberg, Mitchel A. Cole, Claudio Macias-Trevino, Yuichi Ishikawa, Qiuming Yao, Michitaka Nakano, Fumio Arai, Stuart H. Orkin, Bruno Reversade, Silvia Buonamici, Luca Pinello, Koichi Akashi, Daniel E. Bauer, Takahiro Maeda

Cancer Cell. Author manuscript; available in PMC 2019 Mar 12.

Published in final edited form as: Cancer Cell. 2018 Mar 12; 33(3): 386–400.e5. Published online 2018 Feb 22. doi: 10.1016/j.ccell.2018.01.012

PMCID:: PMC5849534

Article PDF–1.1M

Select item 43586599.

The functional interactome of PYHIN immune regulators reveals IFIX is a sensor of viral DNA

Benjamin A Diner, Tuo Li, Todd M Greco, Marni S Crow, John A Fuesler, Jennifer Wang, Ileana M Cristea

Mol Syst Biol. 2015 Feb; 11(2): 787. Published online 2015 Feb 9. doi: 10.15252/msb.20145808

PMCID:: PMC4358659

Article PDF–3.6M

Select item 456372010.

Interactions of the Antiviral Factor Interferon Gamma-Inducible Protein 16 (IFI16) Mediate Immune Signaling and Herpes Simplex Virus-1 Immunosuppression

Benjamin A. Diner, Krystal K. Lum, Aaron Javitt, Ileana M. Cristea

Mol Cell Proteomics. 2015 Sep; 14(9): 2341–2356. Published online 2015 Feb 18. doi: 10.1074/mcp.M114.047068

PMCID:: PMC4563720

Article PDF–2.8M

Select item 302349411.

RioK1, a New Interactor of Protein Arginine Methyltransferase 5 (PRMT5), Competes with pICln for Binding and Modulates PRMT5 Complex Composition and Substrate Specificity

Gernot Guderian, Christoph Peter, Julia Wiesner, Albert Sickmann, Klaus Schulze-Osthoff, Utz Fischer, Matthias Grimmler

J Biol Chem. 2011 Jan 21; 286(3): 1976–1986. Published online 2010 Nov 16. doi: 10.1074/jbc.M110.148486

PMCID:: PMC3023494

Article PDF–4.1M

Select item 1016456412.

The ubiquitin-specific protease USP36 SUMOylates EXOSC10 and promotes the nucleolar RNA exosome function in rRNA processing

Yingxiao Chen, Yanping Li, Roselyn S Dai, Jonathan C Savage, Ujwal Shinde, John Klimek, Larry L David, Emma A Young, Markus Hafner, Rosalie C Sears, Xiao-Xin Sun, Mu-Shui Dai

Nucleic Acids Res. 2023 May 8; 51(8): 3934–3949. Published online 2023 Mar 13. doi: 10.1093/nar/gkad140

PMCID:: PMC10164564

Article PDF–3.8M

Select item 676324213.

Impaired plasma membrane localization of ubiquitin ligase complex underlies 3-M syndrome development

Pu Wang, Feng Yan, Zhijun Li, Yanbao Yu, Scott E. Parnell, Yue Xiong

J Clin Invest. 2019 Oct 1; 129(10): 4393–4407. Published online 2019 Sep 9. doi: 10.1172/JCI129107

PMCID:: PMC6763242

Article PDF–12M

Select item 44214814.

Functional Proteomics Mapping of a Human Signaling Pathway

Frédéric Colland, Xavier Jacq, Virginie Trouplin, Christelle Mougin, Caroline Groizeleau, Alexandre Hamburger, Alain Meil, Jérôme Wojcik, Pierre Legrain, Jean-Michel Gauthier

Genome Res. 2004 Jul; 14(7): 1324–1332. doi: 10.1101/gr.2334104

PMCID:: PMC442148

Article PDF–290K

Select item 573755515.

CHD3 and CHD4 form distinct NuRD complexes with different yet overlapping functionality

Helen Hoffmeister, Andreas Fuchs, Fabian Erdel, Sophia Pinz, Regina Gröbner-Ferreira, Astrid Bruckmann, Rainer Deutzmann, Uwe Schwartz, Rodrigo Maldonado, Claudia Huber, Anne-Sarah Dendorfer, Karsten Rippe, Gernot Längst

Nucleic Acids Res. 2017 Oct 13; 45(18): 10534–10554. Published online 2017 Aug 28. doi: 10.1093/nar/gkx711

PMCID:: PMC5737555

Article PDF–7.2M

Select item 622622516.

PTPN14 regulates Roquin2 stability by tyrosine dephosphorylation

Jaewoo Choi, Anita Saraf, Laurence Florens, Michael P. Washburn, Luca Busino

Cell Cycle. 2018; 17(18): 2243–2255. Published online 2018 Sep 25. doi: 10.1080/15384101.2018.1522912

PMCID:: PMC6226225

Article PDF–1.7M

Select item 826661717.

Matrix-screening reveals a vast potential for direct protein-protein interactions among RNA binding proteins

Benjamin Lang, Jae-Seong Yang, Mireia Garriga-Canut, Silvia Speroni, Moritz Aschern, Maria Gili, Tobias Hoffmann, Gian Gaetano Tartaglia, Sebastian P Maurer

Nucleic Acids Res. 2021 Jul 9; 49(12): 6702–6721. Published online 2021 Jun 16. doi: 10.1093/nar/gkab490

PMCID:: PMC8266617

Article PDF–4.0M

Select item 956995518.

A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation

Yulemi Gonzalez Quesada, Luc DesGroseillers

Int J Mol Sci. 2022 Oct; 23(19): 11588. Published online 2022 Sep 30. doi: 10.3390/ijms231911588

PMCID:: PMC9569955

Article PDF–2.1M

Select item 31107219.

Toward a Catalog of Human Genes and Proteins: Sequencing and Analysis of 500 Novel Complete Protein Coding Human cDNAs

Stefan Wiemann, Bernd Weil, Ruth Wellenreuther, Johannes Gassenhuber, Sabine Glassl, Wilhelm Ansorge, Michael Böcher, Helmut Blöcker, Stefan Bauersachs, Helmut Blum, Jürgen Lauber, Andreas Düsterhöft, Andreas Beyer, Karl Köhrer, Normann Strack, Hans-Werner Mewes, Birgit Ottenwälder, Brigitte Obermaier, Jens Tampe, Dagmar Heubner, Rolf Wambutt, Bernhard Korn, Michaela Klein, Annemarie Poustka

Genome Res. 2001 Mar; 11(3): 422–435. doi: 10.1101/gr.154701

PMCID:: PMC311072

Article PDF–542K

Select item 943393820.

Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB

Fu‐Long Li, Zhengming Wu, Yong‐Qi Gao, Forrest Z Bowling, J Matthew Franklin, Chongze Hu, Raymond T Suhandynata, Michael A Frohman, Michael V Airola, Huilin Zhou, Kun‐Liang Guan

EMBO J. 2022 Sep; 41(17): e110698. Published online 2022 Jul 17. doi: 10.15252/embj.2022110698

PMCID:: PMC9433938

Article PDF–9.3M

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