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Select item 62158971.

Ubiquitin‐specific protease 3 overexpression promotes gastric carcinogenesis and is predictive of poor patient prognosis

Chia‐Lang Fang, Chih‐Chan Lin, Han‐Kun Chen, You‐Cheng Hseu, Shih‐Ting Hung, Ding‐Ping Sun, Yih‐Huei Uen, Kai‐Yuan Lin

Cancer Sci. 2018 Nov; 109(11): 3438–3449. Published online 2018 Sep 21. doi: 10.1111/cas.13789

PMCID:: PMC6215897

Abstract Article PDF–2.3M

Select item 36293782.

UCP3 polymorphisms, hand grip performance and survival at old age: Association analysis in two Danish middle aged and elderly cohorts

Serena Dato, Mette Soerensen, Alberto Montesanto, Vincenzo Lagani, Giuseppe Passarino, Kaare Christensen, Lene Christiansen

Mech Ageing Dev. Author manuscript; available in PMC 2013 Apr 18.

Published in final edited form as: Mech Ageing Dev. 2012 Aug; 133(8): 530–537. Published online 2012 Jun 26. doi: 10.1016/j.mad.2012.06.004

PMCID:: PMC3629378

Abstract Article PDF–863K

Select item 109659933.

USP3 promotes osteosarcoma progression via deubiquitinating EPHA2 and activating the PI3K/AKT signaling pathway

Anan Li, Shijiang Wang, Jiangbo Nie, Shining Xiao, Xinsheng Xie, Yu Zhang, Weilai Tong, Geliang Yao, Ning Liu, Fan Dan, Zhiguo Shu, Jiaming Liu, Zhili Liu, Feng Yang

Cell Death Dis. 2024 Mar; 15(3): 235. Published online 2024 Mar 26. doi: 10.1038/s41419-024-06624-7

PMCID:: PMC10965993

Abstract Article PDF–5.4M

Select item 99452504.

Deubiquitinase ubiquitin-specific protease 3 (USP3) inhibits HIV-1 replication via promoting APOBEC3G (A3G) expression in both enzyme activity-dependent and -independent manners

Simin Zhao, Baisong Zheng, Liuli Wang, Wenzhe Cui, Chunlai Jiang, Zhuo Li, Wenying Gao, Wenyan Zhang

Chin Med J (Engl) 2022 Nov 20; 135(22): 2706–2717. Published online 2022 Dec 27. doi: 10.1097/CM9.0000000000002478

PMCID:: PMC9945250

Abstract Article PDF–2.9M

Select item 95081675.

USP3 deubiquitinates and stabilizes the adapter protein ASC to regulate inflammasome activation

Wanxin Zhuang, Lei Zhang, Yi Zheng, Bingyu Liu, Chunhong Ma, Wei Zhao, Suxia Liu, Feng Liu, Chengjiang Gao

Cell Mol Immunol. 2022 Oct; 19(10): 1141–1152. Published online 2022 Sep 1. doi: 10.1038/s41423-022-00917-7

PMCID:: PMC9508167

Abstract Article PDF–3.8M

Select item 86709676.

MicroRNA-146-5p Promotes Pulmonary Artery Endothelial Cell Proliferation under Hypoxic Conditions through Regulating USP3

Wei Zhang, Yujuan Qi, Bo Wu

Dis Markers. 2021; 2021: 3668422. Published online 2021 Dec 7. doi: 10.1155/2021/3668422

PMCID:: PMC8670967

Abstract Article PDF–1.4M

Select item 85821547.

Protein deubiquitylase USP3 stabilizes Aurora A to promote proliferation and metastasis of esophageal squamous cell carcinoma

Ke Shi, Jin Zhong Zhang, Liang Yang, Ning-Ning Li, Ying Yue, Xiu-Hong Du, Xiu-Zhi Zhang, Yu Cheng Lu, Dan Guo

BMC Cancer. 2021; 21: 1196. Published online 2021 Nov 10. doi: 10.1186/s12885-021-08934-x

PMCID:: PMC8582154

Abstract Article PDF–2.7M

Select item 81975188.

Ubiquitin-Specific Protease 3 Deubiquitinates and Stabilizes Oct4 Protein in Human Embryonic Stem Cells

Byung-Ho Rhie, Ainsley Mike Antao, Janardhan Keshav Karapurkar, Min-Seong Kim, Won-Jun Jo, Suresh Ramakrishna, Kye-Seong Kim

Int J Mol Sci. 2021 Jun; 22(11): 5584. Published online 2021 May 25. doi: 10.3390/ijms22115584

PMCID:: PMC8197518

Abstract Article PDF–6.3M

Select item 75666499.

Genome-scale screening of deubiquitinase subfamily identifies USP3 as a stabilizer of Cdc25A regulating cell cycle in cancer

Soumyadip Das, Arun Pandian Chandrasekaran, Bharathi Suresh, Saba Haq, Jae-Hyeok Kang, Su-Jae Lee, Jaewon Kim, Jaesang Kim, Sanghyuk Lee, Hyongbum Henry Kim, Kye-Seong Kim, Suresh Ramakrishna

Cell Death Differ. 2020 Nov; 27(11): 3004–3020. Published online 2020 May 15. doi: 10.1038/s41418-020-0557-5

PMCID:: PMC7566649

Abstract Article PDF–6.0M

Select item 659192210.

Ubiquitin-specific protease 3 promotes cell migration and invasion by interacting with and deubiquitinating SUZ12 in gastric cancer

Xiaosheng Wu, Mengwei Liu, Huiqiong Zhu, Jing Wang, Weiyu Dai, Jiaying Li, Danping Zhu, Weimei Tang, Yizhi Xiao, Jianjiao Lin, Wenjing Zhang, Yong Sun, Yi Zhang, Yaying Chen, Guoxin Li, Aimin Li, Li Xiang, Side Liu, Jide Wang

J Exp Clin Cancer Res. 2019; 38: 277. Published online 2019 Jun 24. doi: 10.1186/s13046-019-1270-4

PMCID:: PMC6591922

Abstract Article PDF–13M

Select item 922991511.

Exosome-mediated lncRNA SND1-IT1 from gastric cancer cells enhances malignant transformation of gastric mucosa cells via up-regulating SNAIL1

Guohua Jin, Jianguang Zhang, Tingting Cao, Bang Chen, Yu Tian, Yang Shi

J Transl Med. 2022; 20: 284. Published online 2022 Jun 23. doi: 10.1186/s12967-022-03306-w

PMCID:: PMC9229915

Abstract Article PDF–9.3M

Select item 868852412.

USP3 promotes gastric cancer progression and metastasis by deubiquitination-dependent COL9A3/COL6A5 stabilisation

Xiaosheng Wu, Hao Wang, Danping Zhu, Yixia Chai, Jing Wang, Weiyu Dai, Yizhi Xiao, Weimei Tang, Jiaying Li, Linjie Hong, Miaomiao Pei, Jieming Zhang, Zhizhao Lin, Jide Wang, Aimin Li, Side Liu

Cell Death Dis. 2022 Jan; 13(1): 10. Published online 2021 Dec 20. doi: 10.1038/s41419-021-04460-7

PMCID:: PMC8688524

Abstract Article PDF–6.5M

Select item 799438113.

An ALYREF-MYCN coactivator complex drives neuroblastoma tumorigenesis through effects on USP3 and MYCN stability

Zsuzsanna Nagy, Janith A. Seneviratne, Maxwell Kanikevich, William Chang, Chelsea Mayoh, Pooja Venkat, Yanhua Du, Cizhong Jiang, Alice Salib, Jessica Koach, Daniel R. Carter, Rituparna Mittra, Tao Liu, Michael W. Parker, Belamy B. Cheung, Glenn M. Marshall

Nat Commun. 2021; 12: 1881. Published online 2021 Mar 25. doi: 10.1038/s41467-021-22143-x

PMCID:: PMC7994381

Abstract Article PDF–5.5M

Select item 757969014.

LncRNA HOXA‐AS3 promotes the malignancy of glioblastoma through regulating miR‐455‐5p/USP3 axis

Wanghao Chen, Qiaoyu Li, Guilong Zhang, Hong Wang, Zhihan Zhu, Lukui Chen

J Cell Mol Med. 2020 Oct; 24(20): 11755–11767. Published online 2020 Sep 11. doi: 10.1111/jcmm.15788

PMCID:: PMC7579690

Abstract Article PDF–1.8M

Select item 687934115.

USP3 promotes breast cancer cell proliferation by deubiquitinating KLF5

Yingying Wu, Junying Qin, Fubing Li, Chuanyu Yang, Zhen Li, Zhongmei Zhou, Hailin Zhang, Yunxi Li, Xinye Wang, Rong Liu, Qian Tao, Wenlin Chen, Ceshi Chen

J Biol Chem. 2019 Nov 22; 294(47): 17837–17847. Published online 2019 Oct 17. doi: 10.1074/jbc.RA119.009102

PMCID:: PMC6879341

Abstract Article PDF–3.3M

Select item 548732016.

Downregulated USP3 mRNA functions as a competitive endogenous RNA of SMAD4 by sponging miR-224 and promotes metastasis in colorectal cancer

Zaozao Wang, Jie Yang, Jiabo Di, Ming Cui, Jiadi Xing, Fan Wu, Wei Wu, Hong Yang, Chenghai Zhang, Zhendan Yao, Nan Zhang, Beihai Jiang, Xiangqian Su

Sci Rep. 2017; 7: 4281. Published online 2017 Jun 27. doi: 10.1038/s41598-017-04368-3

PMCID:: PMC5487320

Abstract Article PDF–5.5M

Select item 397549617.

USP3 inhibits type I interferon signaling by deubiquitinating RIG-I-like receptors

Jun Cui, Yanxia Song, Yinyin Li, Qingyuan Zhu, Peng Tan, Yunfei Qin, Helen Y Wang, Rong-Fu Wang

Cell Res. 2014 Apr; 24(4): 400–416. Published online 2013 Dec 24. doi: 10.1038/cr.2013.170

PMCID:: PMC3975496

Abstract Article PDF–1.5M

Select item 1017669618.

CRISPR/Cas9-based genome-wide screening of the deubiquitinase subfamily identifies USP3 as a protein stabilizer of REST blocking neuronal differentiation and promotes neuroblastoma tumorigenesis

Janardhan Keshav Karapurkar, Min-Seong Kim, Jencia Carminha Colaco, Bharathi Suresh, Neha Sarodaya, Dong-Ho Kim, Chang-Hwan Park, Seok-Ho Hong, Kye-Seong Kim, Suresh Ramakrishna

J Exp Clin Cancer Res. 2023; 42: 121. Published online 2023 May 12. doi: 10.1186/s13046-023-02694-1