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Select item 103779551.

Loss of PARP7 Increases Type I Interferon Signaling in EO771 Breast Cancer Cells and Prevents Mammary Tumor Growth by Increasing Antitumor Immunity

Marit Rasmussen, Karoline Alvik, Vinicius Kannen, Ninni E. Olafsen, Linnea A. M. Erlingsson, Giulia Grimaldi, Akinori Takaoka, Denis M. Grant, Jason Matthews

Cancers (Basel) 2023 Jul; 15(14): 3689. Published online 2023 Jul 20. doi: 10.3390/cancers15143689

PMCID:: PMC10377955

Article PDF–4.2M

Select item 84049922.

2,3,7,8-Tetrachlorodibenzo-p-Dioxin (TCDD)-Inducible Poly-ADP-Ribose Polymerase (TIPARP/PARP7) Catalytic Mutant Mice (Tiparp^H532A) Exhibit Increased Sensitivity to TCDD-Induced Hepatotoxicity and Lethality

David Hutin, Alexandra S Long, Kim Sugamori, Peng Shao, Sachin Kumar Singh, Marit Rasmussen, Ninni Elise Olafsen, Solveig Pettersen, Giulia Grimaldi, Denis M Grant, Jason Matthews

Toxicol Sci. 2021 Sep; 183(1): 154–169. Published online 2021 Jun 15. doi: 10.1093/toxsci/kfab075

PMCID:: PMC8404992

Article PDF–1.6M

Select item 68831713.

Loss of Tiparp Results in Aberrant Layering of the Cerebral Cortex

Giulia Grimaldi, Barbora Vagaska, Oleksandr Ievglevskyi, Elena Kondratskaya, Joel C. Glover, Jason Matthews

eNeuro. 2019 Nov-Dec; 6(6): ENEURO.0239-19.2019. Prepublished online 2019 Nov 8. Published online 2019 Nov 22. doi: 10.1523/ENEURO.0239-19.2019

Correction in:: eNeuro. 2019 Nov-Dec; 6(6): ENEURO.0519-19.2019.

PMCID:: PMC6883171

Article PDF–2.9M

Select item 65400654.

3-Methylcholanthrene Induces Chylous Ascites in TCDD-Inducible Poly-ADP-Ribose Polymerase (Tiparp) Knockout Mice

Tiffany E. Cho, Debbie Bott, Shaimaa Ahmed, David Hutin, Alvin Gomez, Laura Tamblyn, Angela C. Zhou, Tania H. Watts, Denis M. Grant, Jason Matthews

Int J Mol Sci. 2019 May; 20(9): 2312. Published online 2019 May 10. doi: 10.3390/ijms20092312

PMCID:: PMC6540065

Article PDF–5.9M

Select item 45054295.

Loss of the Mono-ADP-ribosyltransferase, Tiparp, Increases Sensitivity to Dioxin-induced Steatohepatitis and Lethality

Shaimaa Ahmed, Debbie Bott, Alvin Gomez, Laura Tamblyn, Adil Rasheed, Tiffany Cho, Laura MacPherson, Kim S. Sugamori, Yang Yang, Denis M. Grant, Carolyn L. Cummins, Jason Matthews

J Biol Chem. 2015 Jul 3; 290(27): 16824–16840. Published online 2015 May 13. doi: 10.1074/jbc.M115.660100

PMCID:: PMC4505429

Article PDF–6.9M

Select item 87798286.

Reduced Colonic Mucosal Injury in 2,3,7,8-Tetrachlorodibenzo-p-Dioxin Poly ADP-Ribose Polymerase (TIPARP/PARP7)-Deficient Mice

David Hutin, Karoline Alvik Hagen, Peng Shao, Kim Sugamori, Denis M. Grant, Jason Matthews

Int J Mol Sci. 2022 Jan; 23(2): 920. Published online 2022 Jan 15. doi: 10.3390/ijms23020920

PMCID:: PMC8779828

Article PDF–2.7M

Select item 61542747.

Hepatocyte-Specific Deletion of TIPARP, a Negative Regulator of the Aryl Hydrocarbon Receptor, Is Sufficient to Increase Sensitivity to Dioxin-Induced Wasting Syndrome

David Hutin, Laura Tamblyn, Alvin Gomez, Giulia Grimaldi, Helen Soedling, Tiffany Cho, Shaimaa Ahmed, Christin Lucas, Chakravarthi Kanduri, Denis M Grant, Jason Matthews

Toxicol Sci. 2018 Oct; 165(2): 347–360. Published online 2018 Jun 4. doi: 10.1093/toxsci/kfy136

PMCID:: PMC6154274

Article PDF–1.3M

Select item 83189168.

Roles of the ubiquitin ligase CUL4B and ADP-ribosyltransferase TiPARP in TCDD-induced nuclear export and proteasomal degradation of the transcription factor AHR

Mercedes Paz Rijo, Silvia Diani-Moore, Chenyi Yang, Pengbo Zhou, Arleen B. Rifkind

J Biol Chem. 2021 Aug; 297(2): 100886. Published online 2021 Jun 16. doi: 10.1016/j.jbc.2021.100886

PMCID:: PMC8318916

Article PDF–1.6M

Select item 79163789.

Post-Transcriptional Regulation of PARP7 Protein Stability Is Controlled by Androgen Signaling

Teddy Kamata, Chun-Song Yang, Tiffany A. Melhuish, Henry F. Frierson Jr., David Wotton, Bryce M. Paschal

Cells. 2021 Feb; 10(2): 363. Published online 2021 Feb 9. doi: 10.3390/cells10020363

PMCID:: PMC7916378

Article PDF–26M

Select item 700097910.

Murine Coronavirus Infection Activates the Aryl Hydrocarbon Receptor in an Indoleamine 2,3-Dioxygenase-Independent Manner, Contributing to Cytokine Modulation and Proviral TCDD-Inducible-PARP Expression

Matthew E. Grunewald, Mohamed G. Shaban, Samantha R. Mackin, Anthony R. Fehr, Stanley Perlman

J Virol. 2020 Feb; 94(3): e01743-19. Prepublished online 2019 Nov 6. Published online 2020 Jan 17. doi: 10.1128/JVI.01743-19

PMCID:: PMC7000979

Article PDF–5.8M

Select item 610366011.

Novel insight into circular RNA HECTD1 in astrocyte activation via autophagy by targeting MIR142-TIPARP: implications for cerebral ischemic stroke

Bing Han, Yuan Zhang, Yanhong Zhang, Ying Bai, Xufeng Chen, Rongrong Huang, Fangfang Wu, Shuo Leng, Jie Chao, John H. Zhang, Gang Hu, Honghong Yao

Autophagy. 2018; 14(7): 1164–1184. Published online 2018 Jul 20. doi: 10.1080/15548627.2018.1458173

PMCID:: PMC6103660

Article PDF–3.3M

Select item 534761812.

Mitochondrial damage elicits a TCDD-inducible poly(ADP-ribose) polymerase-mediated antiviral response

Tatsuya Kozaki, Jun Komano, Daiki Kanbayashi, Michihiro Takahama, Takuma Misawa, Takashi Satoh, Osamu Takeuchi, Taro Kawai, Shigeomi Shimizu, Yoshiharu Matsuura, Shizuo Akira, Tatsuya Saitoh

Proc Natl Acad Sci U S A. 2017 Mar 7; 114(10): 2681–2686. Published online 2017 Feb 17. doi: 10.1073/pnas.1621508114

PMCID:: PMC5347618

Article PDF–1.2M

Select item 405771113.

Aryl Hydrocarbon Receptor Repressor and TiPARP (ARTD14) Use Similar, but also Distinct Mechanisms to Repress Aryl Hydrocarbon Receptor Signaling

Laura MacPherson, Shaimaa Ahmed, Laura Tamblyn, Jean Krutmann, Irmgard Förster, Heike Weighardt, Jason Matthews

Int J Mol Sci. 2014 May; 15(5): 7939–7957. Published online 2014 May 6. doi: 10.3390/ijms15057939

PMCID:: PMC4057711

Article PDF–1011K

Select item 260076514.

The PDGF signaling pathway controls multiple steroid-producing lineages

Jennifer Schmahl, Kamran Rizzolo, Philippe Soriano

Genes Dev. 2008 Dec 1; 22(23): 3255–3267. doi: 10.1101/gad.1723908

PMCID:: PMC2600765

Article PDF–1.2M

Select item 356200015.

2,3,7,8-Tetrachlorodibenzo-p-dioxin poly(ADP-ribose) polymerase (TiPARP, ARTD14) is a mono-ADP-ribosyltransferase and repressor of aryl hydrocarbon receptor transactivation

Laura MacPherson, Laura Tamblyn, Sharanya Rajendra, Fernando Bralha, J. Peter McPherson, Jason Matthews

Nucleic Acids Res. 2013 Feb; 41(3): 1604–1621. Published online 2012 Dec 25. doi: 10.1093/nar/gks1337

PMCID:: PMC3562000

Article PDF–6.4M

Select item 335508616.

Target Gene Analysis by Microarrays and Chromatin Immunoprecipitation Identifies HEY Proteins as Highly Redundant bHLH Repressors

Julia Heisig, David Weber, Eva Englberger, Anja Winkler, Susanne Kneitz, Wing-Kin Sung, Elmar Wolf, Martin Eilers, Chia-Lin Wei, Manfred Gessler

PLoS Genet. 2012 May; 8(5): e1002728. Published online 2012 May 17. doi: 10.1371/journal.pgen.1002728

PMCID:: PMC3355086

Article PDF–1.4M

Select item 479350117.

Mesodermal ALK5 controls lung myofibroblast versus lipofibroblast cell fate

Aimin Li, Shudong Ma, Susan M. Smith, Matt K. Lee, Ashley Fischer, Zea Borok, Saverio Bellusci, Changgong Li, Parviz Minoo

BMC Biol. 2016; 14: 19. Published online 2016 Mar 16. doi: 10.1186/s12915-016-0242-9

PMCID:: PMC4793501

Article PDF–2.1M

Select item 396495518.

The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data

Gautier Koscielny, Gagarine Yaikhom, Vivek Iyer, Terrence F. Meehan, Hugh Morgan, Julian Atienza-Herrero, Andrew Blake, Chao-Kung Chen, Richard Easty, Armida Di Fenza, Tanja Fiegel, Mark Grifiths, Alan Horne, Natasha A. Karp, Natalja Kurbatova, Jeremy C. Mason, Peter Matthews, Darren J. Oakley, Asfand Qazi, Jack Regnart, Ahmad Retha, Luis A. Santos, Duncan J. Sneddon, Jonathan Warren, Henrik Westerberg, Robert J. Wilson, David G. Melvin, Damian Smedley, Steve D. M. Brown, Paul Flicek, William C. Skarnes, Ann-Marie Mallon, Helen Parkinson

Nucleic Acids Res. 2014 Jan 1; 42(Database issue): D802–D809. Published online 2013 Nov 3. doi: 10.1093/nar/gkt977

PMCID:: PMC3964955

Article PDF–5.7M

Select item 16551119.

BayGenomics: a resource of insertional mutations in mouse embryonic stem cells

Doug Stryke, Michiko Kawamoto, Conrad C. Huang, Susan J. Johns, Leslie A. King, Courtney A. Harper, Elaine C. Meng, Roy E. Lee, Alice Yee, Larry L'Italien, Pao-Tien Chuang, Stephen G. Young, William C. Skarnes, Patricia C. Babbitt, Thomas E. Ferrin

Nucleic Acids Res. 2003 Jan 1; 31(1): 278–281. doi: 10.1093/nar/gkg064

PMCID:: PMC165511

Article PDF–217K

Select item 1683320.

Genome-wide expression profiling of mid-gestation placenta and embryo using a 15,000 mouse developmental cDNA microarray

Tetsuya S. Tanaka, Saied A. Jaradat, Meng K. Lim, George J. Kargul, Xiaohong Wang, Marija J. Grahovac, Serafino Pantano, Yuri Sano, Yulan Piao, Ramaiah Nagaraja, Hirofumi Doi, William H. Wood, III, Kevin G. Becker, Minoru S. H. Ko

Proc Natl Acad Sci U S A. 2000 Aug 1; 97(16): 9127–9132. doi: 10.1073/pnas.97.16.9127

PMCID:: PMC16833

Article PDF–847K

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