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Select item 68636331.

Multiomic analysis of mice epilepsy models suggest that miR-21a expression modulates mRNA and protein levels related to seizure deterioration

XIAOXIAO HU, XIN FU, AO JIANG, XUKUI YANG, XIAODONG FANG, GUOHUA GONG, CHENGXI WEI

Genet Res (Camb) 2015; 97: e22. Published online 2015 Dec 22. doi: 10.1017/S0016672315000245

PMCID:: PMC6863633

Article PDF–279K

Select item 66091052.

Inhibition of ER Stress by 2-Aminopurine Treatment Modulates Cardiomyopathy in a Murine Chronic Chagas Disease Model

Janeesh Plakkal Ayyappan, Kezia lizardo, Sean Wang, Edward Yurkow, Jyothi F Nagajyothi

Biomol Ther (Seoul) 2019 Jul; 27(4): 386–394. Published online 2019 Mar 13. doi: 10.4062/biomolther.2018.193

PMCID:: PMC6609105

Article PDF–6.8M

Select item 65563973.

Overlapping Activities of Two Neuronal Splicing Factors Switch the GABA Effect from Excitatory to Inhibitory by Regulating REST

Yoko Nakano, Susan Wiechert, Botond Bánfi

Cell Rep. Author manuscript; available in PMC 2019 Jun 9.

Published in final edited form as: Cell Rep. 2019 Apr 16; 27(3): 860–871.e8. doi: 10.1016/j.celrep.2019.03.072

PMCID:: PMC6556397

Article PDF–2.3M

Select item 64985854.

Parkinson’s disease-associated LRRK2-G2019S mutant acts through regulation of SERCA activity to control ER stress in astrocytes

Jee Hoon Lee, Ji-hye Han, Hyunmi Kim, Sang Myun Park, Eun-hye Joe, Ilo Jou

Acta Neuropathol Commun. 2019; 7: 68. Published online 2019 May 2. doi: 10.1186/s40478-019-0716-4

PMCID:: PMC6498585

Article PDF–6.9M

Select item 63847535.

The Cardiotoxicity Induced by Arsenic Trioxide is Alleviated by Salvianolic Acid A via Maintaining Calcium Homeostasis and Inhibiting Endoplasmic Reticulum Stress

Ruiying Wang, Jingyi Zhang, Shan Wang, Min Wang, Tianyuan Ye, Yuyang Du, Xueheng Xie, Jingxue Ye, Guibo Sun, Xiaobo Sun

Molecules. 2019 Feb; 24(3): 543. Published online 2019 Feb 2. doi: 10.3390/molecules24030543

PMCID:: PMC6384753

Article PDF–3.4M

Select item 63743646.

Reduced mitochondrial respiration and increased calcium deposits in the EDL muscle, but not in soleus, from 12-week-old dystrophic mdx mice

Rhayanna B. Gaglianone, Anderson Teixeira Santos, Flavia Fonseca Bloise, Tania Maria Ortiga-Carvalho, Manoel Luis Costa, Thereza Quirico-Santos, Wagner Seixas da Silva, Claudia Mermelstein

Sci Rep. 2019; 9: 1986. Published online 2019 Feb 13. doi: 10.1038/s41598-019-38609-4

PMCID:: PMC6374364

Article PDF–2.5M

Select item 62076737.

Cardiomyocyte gene programs encoding morphological and functional signatures in cardiac hypertrophy and failure

Seitaro Nomura, Masahiro Satoh, Takanori Fujita, Tomoaki Higo, Tomokazu Sumida, Toshiyuki Ko, Toshihiro Yamaguchi, Takashige Tobita, Atsuhiko T. Naito, Masamichi Ito, Kanna Fujita, Mutsuo Harada, Haruhiro Toko, Yoshio Kobayashi, Kaoru Ito, Eiki Takimoto, Hiroshi Akazawa, Hiroyuki Morita, Hiroyuki Aburatani, Issei Komuro

Nat Commun. 2018; 9: 4435. Published online 2018 Oct 30. doi: 10.1038/s41467-018-06639-7

PMCID:: PMC6207673

Article PDF–3.1M

Select item 58447008.

Densification of Type I Collagen Matrices as a Model for Cardiac Fibrosis

Logan J. Worke, Jeanne E. Barthold, Benjamin Seelbinder, Tyler Novak, Russell P. Main, Sherry L. Harbin, Corey P. Neu

Adv Healthc Mater. Author manuscript; available in PMC 2018 Nov 1.

Published in final edited form as: Adv Healthc Mater. 2017 Nov; 6(22): 10.1002/adhm.201700114. Published online 2017 Sep 7. doi: 10.1002/adhm.201700114

PMCID:: PMC5844700

Article PDF–1.1M

Select item 58304259.

HCN4 pacemaker channels attenuate the parasympathetic response and stabilize the spontaneous firing of the sinoatrial node

Yuko Kozasa, Noriyuki Nakashima, Masayuki Ito, Taisuke Ishikawa, Hiroki Kimoto, Kazuo Ushijima, Naomasa Makita, Makoto Takano

J Physiol. 2018 Mar 1; 596(5): 809–825. Published online 2018 Feb 6. doi: 10.1113/JP275303

PMCID:: PMC5830425

Article PDF–1.2M

Select item 581465610.

Glucose transporter 4-deficient hearts develop maladaptive hypertrophy in response to physiological or pathological stresses

Adam R. Wende, Jaetaek Kim, William L. Holland, Benjamin E. Wayment, Brian T. O’Neill, Joseph Tuinei, Manoja K. Brahma, Mark E. Pepin, Mark A. McCrory, Ivan Luptak, Ganesh V. Halade, Sheldon E. Litwin, E. Dale Abel

Am J Physiol Heart Circ Physiol. 2017 Dec 1; 313(6): H1098–H1108. Published online 2017 Aug 19. doi: 10.1152/ajpheart.00101.2017

PMCID:: PMC5814656

Article

Select item 541740511.

Triiodothyronine Promotes Cardiac Differentiation and Maturation of Embryonic Stem Cells via the Classical Genomic Pathway

Yee-Ki Lee, Kwong-Man Ng, Yau-Chi Chan, Wing-Hon Lai, Ka-Wing Au, Chung-Yee Jenny Ho, Lai-Yung Wong, Chu-Pak Lau, Hung-Fat Tse, Chung-Wah Siu

Mol Endocrinol. September 1, 2010; 24(9): 1728–1736. doi: 10.1210/me.2010-0032

PMCID:: PMC5417405

Article

Select item 517408112.

Astragaloside IV Attenuates Podocyte Apoptosis Mediated by Endoplasmic Reticulum Stress through Upregulating Sarco/Endoplasmic Reticulum Ca²⁺-ATPase 2 Expression in Diabetic Nephropathy

Hengjiang Guo, Aili Cao, Shuang Chu, Yi Wang, Yingjun Zang, Xiaodong Mao, Hao Wang, Yunman Wang, Cheng Liu, Xuemei Zhang, Wen Peng

Front Pharmacol. 2016; 7: 500. Published online 2016 Dec 21. doi: 10.3389/fphar.2016.00500

PMCID:: PMC5174081

Article PDF–2.8M

Select item 506524813.

Chemotherapeutic Efficacy of Phosphodiesterase Inhibitors in Chagasic Cardiomyopathy

Jian-jun Wen, Xianxiu Wan, John Thacker, Nisha Jain Garg

JACC Basic Transl Sci. 2016 Jun; 1(4): 235–250. Published online 2016 Jun 8. doi: 10.1016/j.jacbts.2016.04.005

PMCID:: PMC5065248

Article PDF–2.3M

Select item 500472114.

Cannabidiol Limits T Cell–Mediated Chronic Autoimmune Myocarditis: Implications to Autoimmune Disorders and Organ Transplantation

Wen-Shin Lee, Katalin Erdelyi, Csaba Matyas, Partha Mukhopadhyay, Zoltan V Varga, Lucas Liaudet, György Hask’, Daniela ’iháková, Raphael Mechoulam, Pal Pacher

Mol Med. 2016; 22: 136–146. Published online 2016 Jan 8. doi: 10.2119/molmed.2016.00007

PMCID:: PMC5004721

Article PDF–4.6M

Select item 482359515.

Myocardial dysfunction occurs prior to changes in ventricular geometry in mice with chronic kidney disease (CKD)

Pamela D. Winterberg, Rong Jiang, Josh T. Maxwell, Bo Wang, Mary B. Wagner

Physiol Rep. 2016 Mar; 4(5): e12732. Published online 2016 Mar 20. doi: 10.14814/phy2.12732

PMCID:: PMC4823595

Article PDF–1.1M

Select item 479729216.

Novel RNA-binding activity of MYF5 enhances Ccnd1/Cyclin D1 mRNA translation during myogenesis

Amaresh C. Panda, Kotb Abdelmohsen, Jennifer L. Martindale, Clara Di Germanio, Xiaoling Yang, Ioannis Grammatikakis, Ji Heon Noh, Yongqing Zhang, Elin Lehrmann, Dawood B. Dudekula, Supriyo De, Kevin G. Becker, Elizabeth J. White, Gerald M. Wilson, Rafael de Cabo, Myriam Gorospe

Nucleic Acids Res. 2016 Mar 18; 44(5): 2393–2408. Published online 2016 Jan 26. doi: 10.1093/nar/gkw023

PMCID:: PMC4797292

Article PDF–4.2M

Select item 450542517.

Insulin-like Growth Factor 2 Overexpression Induces β-Cell Dysfunction and Increases Beta-cell Susceptibility to Damage

Alba Casellas, Cristina Mallol, Ariana Salavert, Veronica Jimenez, Miquel Garcia, Judith Agudo, Mercè Obach, Virginia Haurigot, Laia Vilà, Maria Molas, Ricardo Lage, Meritxell Morró, Estefania Casana, Jesús Ruberte, Fatima Bosch

J Biol Chem. 2015 Jul 3; 290(27): 16772–16785. Published online 2015 May 13. doi: 10.1074/jbc.M115.642041