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Items: 1 to 20 of 27

1.
Cancer-Associated Fibroblasts Suppress CD8+ T-cell Infiltration and Confer Resistance to Immune-Checkpoint Blockade
Liam Jenkins, Ute Jungwirth, Alexandra Avgustinova, Marjan Iravani, Adam Mills, Syed Haider, James Harper, Clare M. Isacke
Cancer Res. 2022 Aug 16; 82(16): 2904–2917. Published online 2022 Jun 24. doi: 10.1158/0008-5472.CAN-21-4141
PMCID:
PMC9379365
AbstractArticlePDF–1.9M
2.
Impairment of a distinct cancer-associated fibroblast population limits tumour growth and metastasis
Ute Jungwirth, Antoinette van Weverwijk, Rachel J. Evans, Liam Jenkins, David Vicente, John Alexander, Qiong Gao, Syed Haider, Marjan Iravani, Clare M. Isacke
Nat Commun. 2021; 12: 3516. Published online 2021 Jun 10. doi: 10.1038/s41467-021-23583-1
PMCID:
PMC8192501
AbstractArticlePDF–6.7M
3.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
4.
CCL2/MCP-1 signaling drives extracellular matrix turnover by diverse macrophage subsets
Henrik J. Jürgensen, Lakmali M. Silva, Oliver Krigslund, Sander van Putten, Daniel H. Madsen, Niels Behrendt, Lars H. Engelholm, Thomas H. Bugge
Matrix Biol Plus. 2019 Feb; 1: 100003. Published online 2019 Mar 19. doi: 10.1016/j.mbplus.2019.03.002
PMCID:
PMC7852312
AbstractArticlePDF–1.0M
5.
Immune regulation by fibroblasts in tissue injury depends on uPARAP-mediated uptake of collectins
Henrik J. Jürgensen, Kirstine S. Nørregaard, Megan M. Sibree, Eric Santoni-Rugiu, Daniel H. Madsen, Katharina Wassilew, Dorrit Krustrup, Peter Garred, Thomas H. Bugge, Lars H. Engelholm, Niels Behrendt
J Cell Biol. 2019 Jan 7; 218(1): 333–349. doi: 10.1083/jcb.201802148
PMCID:
PMC6314555
AbstractArticlePDF–3.7M
6.
Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors
Hyeonwoo Kim, Christiane D. Wrann, Mark Jedrychowski, Sara Vidoni, Yukiko Kitase, Kenichi Nagano, Chenhe Zhou, Joshua Chou, Virginia-Jeni A. Parkman, Scott J. Novick, Timothy S. Strutzenberg, Bruce D. Pascal, Phuong T. Le, Daniel J. Brooks, Alexander M. Roche, Kaitlyn K. Gerber, Laura Mattheis, Wenjing Chen, Hua Tu, Mary L. Bouxsein, Patrick R. Griffin, Roland Baron, Clifford J. Rosen, Lynda F. Bonewald, Bruce M. Spiegelman
Cell. Author manuscript; available in PMC 2019 Dec 13.
Published in final edited form as: Cell. 2018 Dec 13; 175(7): 1756–1768.e17. doi: 10.1016/j.cell.2018.10.025
Correction in:
Cell. 2019 Jul 11; 178(2): 507–508.
PMCID:
PMC6298040
AbstractArticlePDF–1.2M
7.
uPARAP/Endo180 receptor is a gatekeeper of VEGFR-2/VEGFR-3 heterodimerisation during pathological lymphangiogenesis
Tania Durré, Florent Morfoisse, Charlotte Erpicum, Marie Ebroin, Silvia Blacher, Melissa García-Caballero, Christophe Deroanne, Thomas Louis, Cédric Balsat, Maureen Van de Velde, Seppo Kaijalainen, Frédéric Kridelka, Lars Engelholm, Ingrid Struman, Kari Alitalo, Niels Behrendt, Jenny Paupert, Agnès Noel
Nat Commun. 2018; 9: 5178. Published online 2018 Dec 5. doi: 10.1038/s41467-018-07514-1
PMCID:
PMC6281649
AbstractArticlePDF–5.3M
8.
Response by Du et al to Letter Regarding Article “Cardiac Fibroblast-Specific Activating Transcription Factor 3 Protects Against Heart Failure by Suppressing MAP2K3-p38 Signaling”
Jie Du, Xin-liang Ma, Yulin Li, Boya Chen
Circulation. Author manuscript; available in PMC 2018 Nov 21.
Published in final edited form as: Circulation. 2017 Nov 21; 136(21): 2094–2095. doi: 10.1161/CIRCULATIONAHA.117.030421
PMCID:
PMC5863903
ArticlePDF–276K
9.
Rasal2 deficiency reduces adipogenesis and occurrence of obesity-related disorders
Xiaoqiang Zhu, Simin Xie, Tian Xu, Xiaohui Wu, Min Han
Mol Metab. 2017 Jun; 6(6): 494–502. Published online 2017 Mar 18. doi: 10.1016/j.molmet.2017.03.003
PMCID:
PMC5444017
AbstractArticlePDF–2.2M
10.
uPARAP Function in Cutaneous Wound Repair
Maryam G. Rohani, Yu-Hua Chow, Maria V. Razumova, Samuel Ash, Chi F. Hung, Lynn M. Schnapp
PLoS One. 2014; 9(3): e92660. Published online 2014 Mar 24. doi: 10.1371/journal.pone.0092660
PMCID:
PMC3963911
AbstractArticlePDF–966K
11.
M2-like macrophages are responsible for collagen degradation through a mannose receptor–mediated pathway
Daniel H. Madsen, Daniel Leonard, Andrius Masedunskas, Amanda Moyer, Henrik Jessen Jürgensen, Diane E. Peters, Panomwat Amornphimoltham, Arul Selvaraj, Susan S. Yamada, David A. Brenner, Sven Burgdorf, Lars H. Engelholm, Niels Behrendt, Kenn Holmbeck, Roberto Weigert, Thomas H. Bugge
J Cell Biol. 2013 Sep 16; 202(6): 951–966. doi: 10.1083/jcb.201301081
PMCID:
PMC3776354
AbstractArticlePDF–3.8M
12.
Differential Actions of the Endocytic Collagen Receptor uPARAP/Endo180 and the Collagenase MMP-2 in Bone Homeostasis
Daniel H. Madsen, Henrik J. Jürgensen, Signe Ingvarsen, Maria C. Melander, Reidar Albrechtsen, Andreas Hald, Kenn Holmbeck, Thomas H. Bugge, Niels Behrendt, Lars H. Engelholm
PLoS One. 2013; 8(8): e71261. Published online 2013 Aug 5. doi: 10.1371/journal.pone.0071261
PMCID:
PMC3734290
AbstractArticlePDF–12M
13.
Role of Urokinase Plasminogen Activator Receptor–Associated Protein in Mouse Lung
Michael M. Bundesmann, Teresa E. Wagner, Yu-Hua Chow, William A. Altemeier, Trevor Steinbach, Lynn M. Schnapp
Am J Respir Cell Mol Biol. 2012 Feb; 46(2): 233–239. doi: 10.1165/rcmb.2010-0485OC
PMCID:
PMC3297169
AbstractArticlePDF–1.2M
14.
Mannose Receptor 2 Attenuates Renal Fibrosis
Jesús M. López-Guisa, Xiaohe Cai, Sarah J. Collins, Ikuyo Yamaguchi, Daryl M. Okamura, Thomas H. Bugge, Clare M. Isacke, Claire L. Emson, Scott M. Turner, Stuart J. Shankland, Allison A. Eddy
J Am Soc Nephrol. 2012 Feb; 23(2): 236–251. doi: 10.1681/ASN.2011030310
PMCID:
PMC3269177
AbstractArticle
15.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
16.
A Novel Functional Role of Collagen Glycosylation: INTERACTION WITH THE ENDOCYTIC COLLAGEN RECEPTOR uPARAP/ENDO180
Henrik J. Jürgensen, Daniel H. Madsen, Signe Ingvarsen, Maria C. Melander, Henrik Gårdsvoll, Laszlo Patthy, Lars H. Engelholm, Niels Behrendt
J Biol Chem. 2011 Sep 16; 286(37): 32736–32748. Published online 2011 Jul 18. doi: 10.1074/jbc.M111.266692
PMCID:
PMC3173195
AbstractArticlePDF–2.8M
17.
A High-Resolution Anatomical Atlas of the Transcriptome in the Mouse Embryo
Graciana Diez-Roux, Sandro Banfi, Marc Sultan, Lars Geffers, Santosh Anand, David Rozado, Alon Magen, Elena Canidio, Massimiliano Pagani, Ivana Peluso, Nathalie Lin-Marq, Muriel Koch, Marchesa Bilio, Immacolata Cantiello, Roberta Verde, Cristian De Masi, Salvatore A. Bianchi, Juliette Cicchini, Elodie Perroud, Shprese Mehmeti, Emilie Dagand, Sabine Schrinner, Asja Nürnberger, Katja Schmidt, Katja Metz, Christina Zwingmann, Norbert Brieske, Cindy Springer, Ana Martinez Hernandez, Sarah Herzog, Frauke Grabbe, Cornelia Sieverding, Barbara Fischer, Kathrin Schrader, Maren Brockmeyer, Sarah Dettmer, Christin Helbig, Violaine Alunni, Marie-Annick Battaini, Carole Mura, Charlotte N. Henrichsen, Raquel Garcia-Lopez, Diego Echevarria, Eduardo Puelles, Elena Garcia-Calero, Stefan Kruse, Markus Uhr, Christine Kauck, Guangjie Feng, Nestor Milyaev, Chuang Kee Ong, Lalit Kumar, MeiSze Lam, Colin A. Semple, Attila Gyenesei, Stefan Mundlos, Uwe Radelof, Hans Lehrach, Paolo Sarmientos, Alexandre Reymond, Duncan R. Davidson, Pascal Dollé, Stylianos E. Antonarakis, Marie-Laure Yaspo, Salvador Martinez, Richard A. Baldock, Gregor Eichele, Andrea Ballabio
PLoS Biol. 2011 Jan; 9(1): e1000582. Published online 2011 Jan 18. doi: 10.1371/journal.pbio.1000582
PMCID:
PMC3022534
AbstractArticlePDF–3.8M
18.
uPARAP Expression during Murine Lung Development
Leah Smith, Teresa E Wagner, Isham Huizar, Lynn M Schnapp
Gene Expr Patterns. Author manuscript; available in PMC 2009 Sep 1.
Published in final edited form as: Gene Expr Patterns. 2008 Sep; 8(7-8): 486–493. Published online 2008 Jun 28. doi: 10.1016/j.gep.2008.06.006
PMCID:
PMC2613018
AbstractArticlePDF–6.1M
19.
uPARAP/Endo180 is essential for cellular uptake of collagen and promotes fibroblast collagen adhesion
Lars H. Engelholm, Karin List, Sarah Netzel-Arnett, Edna Cukierman, David J. Mitola, Hannah Aaronson, Lars Kjøller, Jørgen K. Larsen, Kenneth M. Yamada, Dudley K. Strickland, Kenn Holmbeck, Keld Danø, Henning Birkedal-Hansen, Niels Behrendt, Thomas H. Bugge
J Cell Biol. 2003 Mar 31; 160(7): 1009–1015. doi: 10.1083/jcb.200211091
PMCID:
PMC2172772
AbstractArticlePDF–237K
20.
Intracellular collagen degradation mediated by uPARAP/Endo180 is a major pathway of extracellular matrix turnover during malignancy
Alejandro C. Curino, Lars H. Engelholm, Susan S. Yamada, Kenn Holmbeck, Leif R. Lund, Alfredo A. Molinolo, Niels Behrendt, Boye Schnack Nielsen, Thomas H. Bugge
J Cell Biol. 2005 Jun 20; 169(6): 977–985. doi: 10.1083/jcb.200411153
PMCID:
PMC2171632
AbstractArticlePDF–3.2M

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