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Select item 111140321.

PTBP1 induces ADAR1 p110 isoform expression through IRES-like dependent translation control and influences cell proliferation in gliomas

Bin Yang, Peishan Hu, Xihua Lin, Wei Han, Liyuan Zhu, Xiaochao Tan, Fei Ye, Guanzhou Wang, Fan Wu, Bin Yin, Zhaoshi Bao, Tao Jiang, Jiangang Yuan, Boqin Qiang, Xiaozhong Peng

Cell Mol Life Sci. 2015 Nov; 72(22): 4383–4397. Published online 2015 Jun 6. doi: 10.1007/s00018-015-1938-7

PMCID:: PMC11114032

Abstract Article PDF–3.0M

Select item 108143882.

RNA Binding Protein PTBP1 Promotes the Metastasis of Gastric Cancer by Stabilizing PGK1 mRNA

Xiaolin Wang, Ce Liang, Shimin Wang, Qiang Ma, Xiaojuan Pan, Ai Ran, Changhong Qin, Bo Huang, Feifei Yang, Yuying Liu, Yuying Zhang, Junwu Ren, Hao Ning, Haiping Li, Yan Jiang, Bin Xiao

Cells. 2024 Jan; 13(2): 140. Published online 2024 Jan 12. doi: 10.3390/cells13020140

PMCID:: PMC10814388

Abstract Article PDF–12M

Select item 107649583.

TRIM28-mediated nucleocapsid protein SUMOylation enhances SARS-CoV-2 virulence

Jiang Ren, Shuai Wang, Zhi Zong, Ting Pan, Sijia Liu, Wei Mao, Huizhe Huang, Xiaohua Yan, Bing Yang, Xin He, Fangfang Zhou, Long Zhang

Nat Commun. 2024; 15: 244. Published online 2024 Jan 4. doi: 10.1038/s41467-023-44502-6

PMCID:: PMC10764958

Abstract Article PDF–4.4M

Select item 106176734.

The midnolin-proteasome pathway catches proteins for ubiquitination-independent degradation

Xin Gu, Christopher Nardone, Nolan Kamitaki, Aoyue Mao, Stephen J. Elledge, Michael E. Greenberg

Science. Author manuscript; available in PMC 2023 Oct 31.

Published in final edited form as: Science. 2023 Aug 25; 381(6660): eadh5021. Published online 2023 Aug 25. doi: 10.1126/science.adh5021

PMCID:: PMC10617673

Abstract Article PDF–3.6M

Select item 105658765.

Pulse-SILAC and Interactomics Reveal Distinct DDB1-CUL4–Associated Factors, Cellular Functions, and Protein Substrates

Jennifer Raisch, Marie-Line Dubois, Marika Groleau, Dominique Lévesque, Thomas Burger, Carla-Marie Jurkovic, Romain Brailly, Gwendoline Marbach, Alyson McKenna, Catherine Barrette, Pierre-Étienne Jacques, François-Michel Boisvert

Mol Cell Proteomics. 2023 Oct; 22(10): 100644. Published online 2023 Sep 7. doi: 10.1016/j.mcpro.2023.100644

PMCID:: PMC10565876

Abstract Article PDF–3.7M

Select item 103819546.

PTBP1 regulates injury responses and sensory pathways in adult peripheral neurons

Stefanie Alber, Pierluigi Di Matteo, Matthew D. Zdradzinski, Irene Dalla Costa, Katalin F. Medzihradszky, Riki Kawaguchi, Agostina Di Pizio, Philip Freund, Nicolas Panayotis, Letizia Marvaldi, Ella Doron-Mandel, Nataliya Okladnikov, Ida Rishal, Reinat Nevo, Giovanni Coppola, Seung Joon Lee, Pabitra K. Sahoo, Alma L. Burlingame, Jeffery L. Twiss, Mike Fainzilber

Sci Adv. 2023 Jul; 9(30): eadi0286. Published online 2023 Jul 28. doi: 10.1126/sciadv.adi0286

PMCID:: PMC10381954

Abstract Article PDF–2.6M

Select item 102446987.

Polypyrimidine tract binding protein 1 (PTBP1) contains a novel regulatory sequence, the rBH3, that binds the prosurvival protein MCL1

Christine Carico, Jia Cui, Alexus Acton, William J. Placzek

J Biol Chem. 2023 Jun; 299(6): 104778. Published online 2023 May 3. doi: 10.1016/j.jbc.2023.104778

PMCID:: PMC10244698

Abstract Article PDF–1.5M

Select item 102374228.

TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan

Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233

PMCID:: PMC10237422

Abstract Article PDF–23M

Select item 101516159.

Cross-linking mass spectrometry discovers, evaluates, and corroborates structures and protein–protein interactions in the human cell

Tara K. Bartolec, Xabier Vázquez-Campos, Alexander Norman, Clement Luong, Marcus Johnson, Richard J. Payne, Marc R. Wilkins, Joel P. Mackay, Jason K. K. Low

Proc Natl Acad Sci U S A. 2023 Apr 25; 120(17): e2219418120. Published online 2023 Apr 18. doi: 10.1073/pnas.2219418120

PMCID:: PMC10151615

Abstract Article PDF–2.9M

Select item 1006741410.

A feedback loop between NONHSAT024276 and PTBP1 inhibits tumor progression and glycolysis in HCC by increasing the PKM1/PKM2 ratio

Yuwei Li, Xia Chen, Hengliu Huang, Ling Liao, Huimin Chong, Guangyao Li, Tao Yuan, Weiping Lu, Shaoli Deng, Qing Huang

Cancer Sci. 2023 Apr; 114(4): 1519–1540. Published online 2022 Dec 27. doi: 10.1111/cas.15697

PMCID:: PMC10067414

Abstract Article PDF–25M

Select item 1003550811.

The Splicing Factor PTBP1 Represses TP63 γ Isoform Production in Squamous Cell Carcinoma

William Taylor, Stéphane Deschamps, David Reboutier, Luc Paillard, Agnès Méreau, Yann Audic

Cancer Res Commun. 2022 Dec; 2(12): 1669–1683. Published online 2022 Dec 20. doi: 10.1158/2767-9764.CRC-22-0350

PMCID:: PMC10035508

Abstract Article PDF–8.5M

Select item 1000623012.

PTBP1 drives c-Myc-dependent gastric cancer progression and stemness

Tengyang Ni, Zewen Chu, Li Tao, Yang Zhao, Miao Zhu, Yuanyuan Luo, Masataka Sunagawa, Haibo Wang, Yanqing Liu

Br J Cancer. 2023 Apr 6; 128(6): 1005–1018. Published online 2023 Jan 12. doi: 10.1038/s41416-022-02118-5

PMCID:: PMC10006230

Abstract Article PDF–4.8M

Select item 998045513.

Analysis of RBP expression and binding sites identifies PTBP1 as a regulator of CD19 expression in B-ALL

Nicole Ziegler, Mariela Cortés-López, Francesca Alt, Maximilian Sprang, Arsenij Ustjanzew, Nadine Lehmann, Khalifa El Malki, Arthur Wingerter, Alexandra Russo, Olaf Beck, Sebastian Attig, Lea Roth, Julian König, Claudia Paret, Jörg Faber

Oncoimmunology. 2023; 12(1): 2184143. Published online 2023 Mar 1. doi: 10.1080/2162402X.2023.2184143

PMCID:: PMC9980455

Abstract Article PDF–1.8M

Select item 997863514.

Fibril treatment changes protein interactions of tau and α-synuclein in human neurons

Tagan A. Griffin, Paul D. Schnier, Elisa M. Cleveland, Robert W. Newberry, Julia Becker, George A. Carlson

J Biol Chem. 2023 Mar; 299(3): 102888. Published online 2023 Jan 10. doi: 10.1016/j.jbc.2023.102888

PMCID:: PMC9978635

Abstract Article PDF–10M

Select item 997294515.

Transferrin Receptor Protein 1 Cooperates with mGluR2 To Mediate the Internalization of Rabies Virus and SARS-CoV-2

Xinxin Wang, Zhiyuan Wen, Huizhen Cao, Jie Luo, Lei Shuai, Chong Wang, Jinying Ge, Xijun Wang, Zhigao Bu, Jinliang Wang

J Virol. 2023 Feb; 97(2): e01611-22. Published online 2023 Feb 13. doi: 10.1128/jvi.01611-22

PMCID:: PMC9972945

Abstract Article PDF–3.0M

Select item 995044716.

Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma

Yu-Fei Cao, Lei Xie, Bei-Bei Tong, Man-Yu Chu, Wen-Qi Shi, Xiang Li, Jian-Zhong He, Shao-Hong Wang, Zhi-Yong Wu, Dan-Xia Deng, Ya-Qi Zheng, Zhi-Mao Li, Xiu-E Xu, Lian-Di Liao, Yin-Wei Cheng, Li-Yan Li, Li-Yan Xu, En-Min Li

Cell Death Differ. 2023 Feb; 30(2): 527–543. Published online 2022 Dec 16. doi: 10.1038/s41418-022-01104-x

PMCID:: PMC9950447

Abstract Article PDF–8.4M

Select item 993206217.

Long noncoding RNA ENST00000436340 promotes podocyte injury in diabetic kidney disease by facilitating the association of PTBP1 with RAB3B

Jinxiu Hu, Qimeng Wang, Xiaoting Fan, Junhui Zhen, Cheng Wang, Huimin Chen, Yingxiao Liu, Ping Zhou, Tingwei Zhang, Tongtong Huang, Rong Wang, Zhimei Lv

Cell Death Dis. 2023 Feb; 14(2): 130. Published online 2023 Feb 15. doi: 10.1038/s41419-023-05658-7

PMCID:: PMC9932062

Abstract Article PDF–7.0M

Select item 988113618.

The histone acetyltransferase KAT6A is recruited to unmethylated CpG islands via a DNA binding winged helix domain

Lisa Marie Weber, Yulin Jia, Bastian Stielow, Stephen S Gisselbrecht, Yinghua Cao, Yanpeng Ren, Iris Rohner, Jessica King, Elisabeth Rothman, Sabrina Fischer, Clara Simon, Ignasi Forné, Andrea Nist, Thorsten Stiewe, Martha L Bulyk, Zhanxin Wang, Robert Liefke

Nucleic Acids Res. 2023 Jan 25; 51(2): 574–594. Published online 2022 Dec 20. doi: 10.1093/nar/gkac1188

PMCID:: PMC9881136

Abstract Article PDF–4.4M

Select item 986889019.

The PTBP1‑NCOA4 axis promotes ferroptosis in liver cancer cells

Hao Yang, Wensheng Sun, Tao Bi, Qi Wang, Wentao Wang, Youxin Xu, Zhiqian Liu, Jie Li

Oncol Rep. 2023 Feb; 49(2): 45. Published online 2023 Jan 13. doi: 10.3892/or.2023.8482

PMCID:: PMC9868890

Abstract Article PDF–4.0M

Select item 986477220.

Polypyrimidine-Tract-Binding Protein Isoforms Differentially Regulate the Hepatitis C Virus Internal Ribosome Entry Site

Jenniffer Angulo, C. Joaquín Cáceres, Nataly Contreras, Leandro Fernández-García, Nathalie Chamond, Melissa Ameur, Bruno Sargueil, Marcelo López-Lastra

Viruses. 2023 Jan; 15(1): 8. Published online 2022 Dec 20. doi: 10.3390/v15010008