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Items: 1 to 20 of 136

1.
A recurrent de novo MAX p.Arg60Gln variant causes a syndromic overgrowth disorder through differential expression of c-Myc target genes
Erica L. Harris, Vincent Roy, Martin Montagne, Ailsa M.S. Rose, Helen Livesey, Margot R.F. Reijnders, Emma Hobson, Francis H. Sansbury, Marjolein H. Willemsen, Rolph Pfundt, Daniel Warren, Vernon Long, Ian M. Carr, Han G. Brunner, Eamonn G. Sheridan, Helen V. Firth, Pierre Lavigne, James A. Poulter
Am J Hum Genet. 2024 Jan 4; 111(1): 119–132. Published online 2023 Dec 22. doi: 10.1016/j.ajhg.2023.11.010
PMCID:
PMC10806738
AbstractArticlePDF–4.9M
2.
NMR‐identification of the interaction between BRCA1 and the intrinsically disordered monomer of the Myc‐associated factor X
Ludovica Martina Epasto, Christopher Pötzl, Herwig Peterlik, Mahdi Khalil, Christine Saint‐Pierre, Didier Gasparutto, Giuseppe Sicoli, Dennis Kurzbach
Protein Sci. 2024 Jan; 33(1): e4849. Published online 2024 Jan 1. doi: 10.1002/pro.4849
PMCID:
PMC10731500
AbstractArticlePDF–842K
3.
Validation of Myc-Associated Protein X (MAX) regulation in growth hormone secreting and nonfunctional pituitary adenoma
Douglass W. Tucker, Dhiraj J. Pangal, Robin Du, Angad S. Gogia, Ali Tafreshi, Jacob Ruzevick, Kyle T. Hurth, Tim Triche, Jr, Alexander Micko, John D. Carpten, Mark S. Shiroishi, John D. Carmichael, Suhn K. Rhie, Gabriel Zada
PLoS One. 2023; 18(4): e0284949. Published online 2023 Apr 27. doi: 10.1371/journal.pone.0284949
PMCID:
PMC10138191
AbstractArticlePDF–1.6M
4.
P300 Interacted With N-Myc and Regulated Its Protein Stability via Altering Its Post-Translational Modifications in Neuroblastoma
Cheng Cheng, Tian He, Kai Chen, Yuanxia Cai, Yaoyao Gu, Lijia Pan, Peiwen Duan, Yeming Wu, Zhixiang Wu
Mol Cell Proteomics. 2023 Mar; 22(3): 100504. Published online 2023 Jan 26. doi: 10.1016/j.mcpro.2023.100504
PMCID:
PMC9984901
AbstractArticlePDF–4.3M
5.
Inhibition of USP1 reverses the chemotherapy resistance through destabilization of MAX in the relapsed/refractory B-cell lymphoma
Xi-Ya Li, Ji-Chuan Wu, Ping Liu, Zi-Juan Li, Yong Wang, Bing-Yi Chen, Cheng-Long Hu, Ming-Yue Fei, Peng-Cheng Yu, Yi-Lun Jiang, Chun-Hui Xu, Bin-He Chang, Xin-Chi Chen, Li-Juan Zong, Jia-Ying Zhang, Ying Fang, Xiao-Jian Sun, Kai Xue, Li Wang, Shu-Bei Chen, Shi-Yu Jiang, Ai-ling Gui, Ling Yang, Juan J. Gu, Bao-Hua Yu, Qun-ling Zhang, Lan Wang
Leukemia. 2023; 37(1): 164–177. Published online 2022 Nov 9. doi: 10.1038/s41375-022-01747-2
PMCID:
PMC9883169
AbstractArticlePDF–6.6M
6.
EZH2 non-canonically binds cMyc and p300 through a cryptic transactivation domain to mediate gene activation and promote oncogenesis
Jun Wang, Xufen Yu, Weida Gong, Xijuan Liu, Kwang-Su Park, Anqi Ma, Yi-Hsuan Tsai, Yudao Shen, Takashi Onikubo, Wen-Chieh Pi, David F. Allison, Jing Liu, Wei-Yi Chen, Ling Cai, Robert G. Roeder, Jian Jin, Gang Greg Wang
Nat Cell Biol. Author manuscript; available in PMC 2022 Nov 30.
Published in final edited form as: Nat Cell Biol. 2022 Mar; 24(3): 384–399. Published online 2022 Feb 24. doi: 10.1038/s41556-022-00850-x
PMCID:
PMC9710513
AbstractArticlePDF–7.9M
7.
The in vivo Interaction Landscape of Histones H3.1 and H3.3
Robert Siddaway, Scott Milos, Étienne Coyaud, Hwa Young Yun, Shahir M. Morcos, Sanja Pajovic, Eric I. Campos, Brian Raught, Cynthia Hawkins
Mol Cell Proteomics. 2022 Oct; 21(10): 100411. Published online 2022 Sep 9. doi: 10.1016/j.mcpro.2022.100411
PMCID:
PMC9540345
AbstractArticlePDF–3.9M
8.
Succinate dehydrogenase and MYC-associated factor X mutations in pituitary neuroendocrine tumours
Paul Benjamin Loughrey, Federico Roncaroli, Estelle Healy, Philip Weir, Madhu Basetti, Ruth T Casey, Steven J Hunter, Márta Korbonits
Endocr Relat Cancer. 2022 Oct 1; 29(10): R157–R172. Published online 2022 Aug 8. doi: 10.1530/ERC-22-0157
PMCID:
PMC9513646
AbstractArticlePDF–3.1M
9.
miR-22 Suppresses EMT by Mediating Metabolic Reprogramming in Colorectal Cancer through Targeting MYC-Associated Factor X
Shusen Xia, Xianyan Wang, Yi Wu, Tong Zhou, Hongpeng Tian, Zuoliang Liu, Lifa Li, Zaihua Yan, Guangjun Zhang
Dis Markers. 2022; 2022: 7843565. Published online 2022 Aug 25. doi: 10.1155/2022/7843565
PMCID:
PMC9436592
AbstractArticlePDF–3.9M
10.
Interaction of LATS1 with SMAC links the MST2/Hippo pathway with apoptosis in an IAP-dependent manner
Lucía García-Gutiérrez, Emma Fallahi, Nourhan Aboud, Niall Quinn, David Matallanas
Cell Death Dis. 2022 Aug; 13(8): 692. Published online 2022 Aug 8. doi: 10.1038/s41419-022-05147-3
PMCID:
PMC9360443
AbstractArticlePDF–5.8M
11.
PCGF6 controls neuroectoderm specification of human pluripotent stem cells by activating SOX2 expression
Xianchun Lan, Song Ding, Tianzhe Zhang, Ying Yi, Conghui Li, Wenwen Jin, Jian Chen, Kaiwei Liang, Hengbin Wang, Wei Jiang
Nat Commun. 2022; 13: 4601. Published online 2022 Aug 6. doi: 10.1038/s41467-022-32295-z
PMCID:
PMC9357003
AbstractArticlePDF–3.7M
12.
Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery
Pierre C. Havugimana, Raghuveera Kumar Goel, Sadhna Phanse, Ahmed Youssef, Dzmitry Padhorny, Sergei Kotelnikov, Dima Kozakov, Andrew Emili
Nat Commun. 2022; 13: 4043. Published online 2022 Jul 13. doi: 10.1038/s41467-022-31809-z
PMCID:
PMC9279285
AbstractArticlePDF–2.5M
13.
OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization
Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti
Science. Author manuscript; available in PMC 2022 Sep 11.
Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983
PMCID:
PMC9119736
AbstractArticlePDF–3.3M
14.
Genome-wide CRISPR screens using isogenic cells reveal vulnerabilities conferred by loss of tumor suppressors
Xu Feng, Mengfan Tang, Merve Dede, Dan Su, Guangsheng Pei, Dadi Jiang, Chao Wang, Zhen Chen, Mi Li, Litong Nie, Yun Xiong, Siting Li, Jeong-Min Park, Huimin Zhang, Min Huang, Klaudia Szymonowicz, Zhongming Zhao, Traver Hart, Junjie Chen
Sci Adv. 2022 May; 8(19): eabm6638. Published online 2022 May 13. doi: 10.1126/sciadv.abm6638
PMCID:
PMC9106303
AbstractArticlePDF–918K
15.
Functional inhibition of c-Myc using novel inhibitors identified through “hot spot” targeting
Ashutosh Singh, Prateek Kumar, Sailu Sarvagalla, Taniya Bharadwaj, Namyashree Nayak, Mohane Selvaraj Coumar, Rajanish Giri, Neha Garg
J Biol Chem. 2022 May; 298(5): 101898. Published online 2022 Apr 1. doi: 10.1016/j.jbc.2022.101898
PMCID:
PMC9065629
AbstractArticlePDF–4.5M
16.
MAX deficiency impairs human endometrial decidualization through down-regulating OSR2 in women with recurrent spontaneous abortion
Weixu Ma, Mingzhu Cao, Shilei Bi, Lili Du, Jingsi Chen, Haibin Wang, Yufei Jiang, Yixuan Wu, Yixin Liao, Shuangbo Kong, Jianqiao Liu
Cell Tissue Res. 2022; 388(2): 453–469. Published online 2022 Feb 11. doi: 10.1007/s00441-022-03579-z
PMCID:
PMC9035420
AbstractArticlePDF–12M
17.
A protein network map of head and neck cancer reveals PIK3CA mutant drug sensitivity
Danielle L. Swaney, Dana J. Ramms, Zhiyong Wang, Jisoo Park, Yusuke Goto, Margaret Soucheray, Neil Bhola, Kyumin Kim, Fan Zheng, Yan Zeng, Michael McGregor, Kari A. Herrington, Rachel O’Keefe, Nan Jin, Nathan K. VanLandingham, Helene Foussard, John Von Dollen, Mehdi Bouhaddou, David Jimenez-Morales, Kirsten Obernier, Jason F. Kreisberg, Minkyu Kim, Daniel E. Johnson, Natalia Jura, Jennifer R. Grandis, J. Silvio Gutkind, Trey Ideker, Nevan J. Krogan
Science. Author manuscript; available in PMC 2022 Apr 13.
Published in final edited form as: Science. 2021 Oct; 374(6563): eabf2911. Published online 2021 Oct 1. doi: 10.1126/science.abf2911
PMCID:
PMC9005332
AbstractArticlePDF–2.0M
18.
Human transcription factor protein interaction networks
Helka Göös, Matias Kinnunen, Kari Salokas, Zenglai Tan, Xiaonan Liu, Leena Yadav, Qin Zhang, Gong-Hong Wei, Markku Varjosalo
Nat Commun. 2022; 13: 766. Published online 2022 Feb 9. doi: 10.1038/s41467-022-28341-5
PMCID:
PMC8828895
AbstractArticlePDF–1.7M
19.
EZH2 depletion potentiates MYC degradation inhibiting neuroblastoma and small cell carcinoma tumor formation
Liyuan Wang, Chan Chen, Zemin Song, Honghong Wang, Minghui Ye, Donghai Wang, Wenqian Kang, Hudan Liu, Guoliang Qing
Nat Commun. 2022; 13: 12. Published online 2022 Jan 10. doi: 10.1038/s41467-021-27609-6
PMCID:
PMC8748958
AbstractArticlePDF–3.0M
20.
The proximal proteome of 17 SARS-CoV-2 proteins links to disrupted antiviral signaling and host translation
Jordan M. Meyers, Muthukumar Ramanathan, Ronald L. Shanderson, Aimee Beck, Laura Donohue, Ian Ferguson, Margaret G. Guo, Deepti S. Rao, Weili Miao, David Reynolds, Xue Yang, Yang Zhao, Yen-Yu Yang, Catherine Blish, Yinsheng Wang, Paul A. Khavari
PLoS Pathog. 2021 Oct; 17(10): e1009412. Published online 2021 Oct 1. doi: 10.1371/journal.ppat.1009412
PMCID:
PMC8513853
AbstractArticlePDF–4.1M

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