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Select item 107999031.

Proteomic analysis of SARS-CoV-2 particles unveils a key role of G3BP proteins in viral assembly

Emilie Murigneux, Laurent Softic, Corentin Aubé, Carmen Grandi, Delphine Judith, Johanna Bruce, Morgane Le Gall, François Guillonneau, Alain Schmitt, Vincent Parissi, Clarisse Berlioz-Torrent, Laurent Meertens, Maike M. K. Hansen, Sarah Gallois-Montbrun

Nat Commun. 2024; 15: 640. Published online 2024 Jan 20. doi: 10.1038/s41467-024-44958-0

PMCID:: PMC10799903

Abstract Article PDF–25M

Select item 107649582.

TRIM28-mediated nucleocapsid protein SUMOylation enhances SARS-CoV-2 virulence

Jiang Ren, Shuai Wang, Zhi Zong, Ting Pan, Sijia Liu, Wei Mao, Huizhe Huang, Xiaohua Yan, Bing Yang, Xin He, Fangfang Zhou, Long Zhang

Nat Commun. 2024; 15: 244. Published online 2024 Jan 4. doi: 10.1038/s41467-023-44502-6

PMCID:: PMC10764958

Abstract Article PDF–4.4M

Select item 106883513.

Emerging role of cyclophilin A in HIV-1 infection: from producer cell to the target cell nucleus

Adrian Padron, Prem Prakash, Jui Pandhare, Jeremy Luban, Chris Aiken, Muthukumar Balasubramaniam, Chandravanu Dash

J Virol. 2023 Nov; 97(11): e00732-23. Published online 2023 Oct 16. doi: 10.1128/jvi.00732-23

PMCID:: PMC10688351

Abstract Article PDF–801K

Select item 106259874.

Bioinformatics analysis and experimental validation of tumorigenic role of PPIA in gastric cancer

Jichao Liu, Yanjun Wang, Zhiwei Zhao, Yanhui Ge

Sci Rep. 2023; 13: 19116. Published online 2023 Nov 5. doi: 10.1038/s41598-023-46508-y

PMCID:: PMC10625987

Abstract Article PDF–9.6M

Select item 106176735.

The midnolin-proteasome pathway catches proteins for ubiquitination-independent degradation

Xin Gu, Christopher Nardone, Nolan Kamitaki, Aoyue Mao, Stephen J. Elledge, Michael E. Greenberg

Science. Author manuscript; available in PMC 2023 Oct 31.

Published in final edited form as: Science. 2023 Aug 25; 381(6660): eadh5021. Published online 2023 Aug 25. doi: 10.1126/science.adh5021

PMCID:: PMC10617673

Abstract Article PDF–3.6M

Select item 105313136.

New Insights into Dyskerin-CypA Interaction: Implications for X-Linked Dyskeratosis Congenita and Beyond

Valentina Belli, Daniela Maiello, Concetta Di Lorenzo, Maria Furia, Rosario Vicidomini, Mimmo Turano

Genes (Basel) 2023 Sep; 14(9): 1766. Published online 2023 Sep 6. doi: 10.3390/genes14091766

PMCID:: PMC10531313

Abstract Article PDF–2.5M

Select item 104472397.

TRIM5α restricts poxviruses and is antagonized by CypA and the viral protein C6

Yiqi Zhao, Yongxu Lu, Samuel Richardson, Meghna Sreekumar, Jonas D. Albarnaz, Geoffrey L. Smith

Nature. 2023; 620(7975): 873–880. Published online 2023 Aug 9. doi: 10.1038/s41586-023-06401-0

PMCID:: PMC10447239

Abstract Article PDF–10M

Select item 102374228.

TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan

Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233

PMCID:: PMC10237422

Abstract Article PDF–23M

Select item 101348899.

A Tripartite Complex HIV-1 Tat-Cyclophilin A-Capsid Protein Enables Tat Encapsidation That Is Required for HIV-1 Infectivity

Malvina Schatz, Laetitia Marty, Camille Ounadjela, Phuoc Bao Viet Tong, Ilaria Cardace, Clément Mettling, Pierre-Emmanuel Milhiet, Luca Costa, Cédric Godefroy, Martine Pugnière, Jean-François Guichou, Jean-Michel Mesnard, Mickaël Blaise, Bruno Beaumelle

J Virol. 2023 Apr; 97(4): e00278-23. Published online 2023 Apr 11. doi: 10.1128/jvi.00278-23

PMCID:: PMC10134889

Abstract Article PDF–1.3M

Select item 1001945110.

Molecular insight into the specific interactions of the SARS‐Coronavirus‐2 nucleocapsid with RNA and host protein

Eunjeong Lee, Jasmina S. Redzic, Anthony J. Saviola, Xueni Li, Christopher C. Ebmeier, Tatiana Kutateladze, Kirk Charles Hansen, Rui Zhao, Natalie Ahn, Nikolai N. Sluchanko, Elan Eisenmesser

Protein Sci. 2023 Apr; 32(4): e4603. Published online 2023 Apr 1. doi: 10.1002/pro.4603

PMCID:: PMC10019451

Abstract Article PDF–5.5M

Select item 995044711.

Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma

Yu-Fei Cao, Lei Xie, Bei-Bei Tong, Man-Yu Chu, Wen-Qi Shi, Xiang Li, Jian-Zhong He, Shao-Hong Wang, Zhi-Yong Wu, Dan-Xia Deng, Ya-Qi Zheng, Zhi-Mao Li, Xiu-E Xu, Lian-Di Liao, Yin-Wei Cheng, Li-Yan Li, Li-Yan Xu, En-Min Li

Cell Death Differ. 2023 Feb; 30(2): 527–543. Published online 2022 Dec 16. doi: 10.1038/s41418-022-01104-x

PMCID:: PMC9950447

Abstract Article PDF–8.4M

Select item 987484012.

Cyclophilin A‐mediated mitigation of coronavirus SARS‐CoV‐2

Simranjeet Singh Sekhon, Woo‐Ri Shin, Sang Yong Kim, Dong‐Seok Jeong, Wooil Choi, Bong‐Keun Choi, Jiho Min, Ji‐Young Ahn, Yang‐Hoon Kim

Bioeng Transl Med. 2023 Mar; 8(2): e10436. Published online 2022 Oct 27. doi: 10.1002/btm2.10436

PMCID:: PMC9874840

Abstract Article PDF–6.6M

Select item 979798813.

TBK1 posphorylation activates LIR-dependent degradation of the inflammation repressor TNIP1

Jianwen Zhou, Nikoline Lander Rasmussen, Hallvard Lauritz Olsvik, Vyacheslav Akimov, Zehan Hu, Gry Evjen, Stéphanie Kaeser-Pebernard, Devanarayanan Siva Sankar, Carole Roubaty, Pauline Verlhac, Nicole van de Beek, Fulvio Reggiori, Yakubu Princely Abudu, Blagoy Blagoev, Trond Lamark, Terje Johansen, Jörn Dengjel

J Cell Biol. 2023 Feb 6; 222(2): e202108144. Published online 2022 Dec 27. doi: 10.1083/jcb.202108144

PMCID:: PMC9797988

Abstract Article PDF–6.9M

Select item 973393714.

Oncogenic deubiquitination controls tyrosine kinase signaling and therapy response in acute lymphoblastic leukemia

Qi Jin, Blanca Gutierrez Diaz, Tim Pieters, Yalu Zhou, Sonali Narang, Igor Fijalkwoski, Cristina Borin, Jolien Van Laere, Monique Payton, Byoung-Kyu Cho, Cuijuan Han, Limin Sun, Valentina Serafin, George Yacu, Wouter Von Loocke, Giuseppe Basso, Giulia Veltri, Ingrid Dreveny, Issam Ben-Sahra, Young Ah Goo, Stephanie L. Safgren, Yi-Chien Tsai, Beat Bornhauser, Praveen Kumar Suraneni, Alexandre Gaspar-Maia, Irawati Kandela, Pieter Van Vlierberghe, John D. Crispino, Aristotelis Tsirigos, Panagiotis Ntziachristos

Sci Adv. 2022 Dec; 8(49): eabq8437. Published online 2022 Dec 9. doi: 10.1126/sciadv.abq8437

PMCID:: PMC9733937

Abstract Article PDF–2.2M

Select item 970808615.

The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers

Martina Oravcová, Minghua Nie, Nicola Zilio, Shintaro Maeda, Yasaman Jami-Alahmadi, Eros Lazzerini-Denchi, James A Wohlschlegel, Helle D Ulrich, Takanori Otomo, Michael N Boddy

eLife. 2022; 11: e79676. Published online 2022 Nov 14. doi: 10.7554/eLife.79676

PMCID:: PMC9708086

Abstract Article PDF–8.5M

Select item 966294516.

Interactome of Aiolos/Ikaros Reveals Combination Rationale of Cereblon Modulators with HDAC Inhibitors in DLBCL

Patrick R. Hagner, Hsiling Chiu, Vivek S. Chopra, Martino Colombo, Nisha Patel, Maria Ortiz Estevez, Michelle F. Waldman, Remco Loos, Fadi Towfic, Anita K. Gandhi

Clin Cancer Res. 2022 Aug 2; 28(15): 3367–3377. Published online 2022 May 18. doi: 10.1158/1078-0432.CCR-21-3347

PMCID:: PMC9662945

Abstract Article PDF–1.6M

Select item 956347117.

Clinical and Prognostic Value of PPIA, SQSTM1, and CCL20 in Hepatocellular Carcinoma Patients by Single-Cell Transcriptome Analysis

Lisha Mou, Chenyang Jia, Zijing Wu, Boyang Xin, Carmen Alicia Liang Zhen, Bailiang Wang, Yong Ni, Zuhui Pu

Cells. 2022 Oct; 11(19): 3078. Published online 2022 Sep 30. doi: 10.3390/cells11193078

PMCID:: PMC9563471

Abstract Article PDF–4.5M

Select item 952399718.

MBD5 and MBD6 stabilize the BAP1 complex and promote BAP1-dependent cancer

Natsumi Tsuboyama, Aileen Patricia Szczepanski, Zibo Zhao, Lu Wang

Genome Biol. 2022; 23: 206. Published online 2022 Sep 30. doi: 10.1186/s13059-022-02776-x

PMCID:: PMC9523997

Abstract Article PDF–6.9M

Select item 952364519.

SARS-CoV-2 Nsp6 damages Drosophila heart and mouse cardiomyocytes through MGA/MAX complex-mediated increased glycolysis

Jun-yi Zhu, Guanglei Wang, Xiaohu Huang, Hangnoh Lee, Jin-Gu Lee, Penghua Yang, Joyce van de Leemput, Weiliang Huang, Maureen A. Kane, Peixin Yang, Zhe Han

Commun Biol. 2022; 5: 1039. Published online 2022 Sep 30. doi: 10.1038/s42003-022-03986-6

PMCID:: PMC9523645

Abstract Article PDF–3.9M

Select item 948193320.

ALS-linked loss of Cyclin-F function affects HSP90

Alexander Siebert, Vanessa Gattringer, Jochen H Weishaupt, Christian Behrends

Life Sci Alliance. 2022 Dec; 5(12): e202101359. Published online 2022 Sep 16. doi: 10.26508/lsa.202101359

PMCID:: PMC9481933

Abstract Article PDF–3.5M

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