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Select item 108242701.

Protease activated receptors and glycoprotein VI cooperatively drive the platelet component in thromboelastography

Tanvi Rudran, Silvio Antoniak, Matthew J Flick, Mark H Ginsberg, Alisa S Wolberg, Wolfgang Bergmeier, Robert H Lee

J Thromb Haemost. Author manuscript; available in PMC 2024 Jan 29.

Published in final edited form as: J Thromb Haemost. 2023 Aug; 21(8): 2236–2247. Published online 2023 Apr 15. doi: 10.1016/j.jtha.2023.04.008

PMCID:: PMC10824270

Abstract Article PDF–1.3M

Select item 101783612.

Differential Regulation of GPVI-Induced Btk and Syk Activation by PKC, PKA and PP2A in Human Platelets

Pengyu Zhang, Fiorella A. Solari, Johan W. M. Heemskerk, Marijke J. E. Kuijpers, Albert Sickmann, Ulrich Walter, Kerstin Jurk

Int J Mol Sci. 2023 May; 24(9): 7776. Published online 2023 Apr 24. doi: 10.3390/ijms24097776

PMCID:: PMC10178361

Abstract Article PDF–3.2M

Select item 93275293.

GPVI expression is linked to platelet size, age, and reactivity

Alicia Veninga, Stefan Handtke, Konstanze Aurich, Bibian M. E. Tullemans, Sanne L. N. Brouns, Silas L. Schwarz, Floor C. J. I. Heubel-Moenen, Andreas Greinacher, Johan W. M. Heemskerk, Paola E. J. van der Meijden, Thomas Thiele

Blood Adv. 2022 Jul 26; 6(14): 4162–4173. Published online 2022 Jul 19. doi: 10.1182/bloodadvances.2021006904

PMCID:: PMC9327529

Abstract Article PDF–2.3M

Select item 87656404.

Platelet surface receptor glycoprotein VI-dimer is overexpressed in stroke: The Glycoprotein VI in Stroke (GYPSIE) study results

Isuru Induruwa, Harriet McKinney, Carly Kempster, Patrick Thomas, Joana Batista, Jean-Daniel Malcor, Arkadiusz Bonna, Joanne McGee, Elaine Bumanlag-Amis, Karola Rehnstrom, Sophie Ashford, Kenji Soejima, Willem Ouwehand, Richard Farndale, Kate Downes, Elizabeth Warburton, Masaaki Moroi, Stephanie Jung

PLoS One. 2022; 17(1): e0262695. Published online 2022 Jan 18. doi: 10.1371/journal.pone.0262695

PMCID:: PMC8765640

Abstract Article PDF–1.6M

Select item 79285155.

Long-term platelet priming after glycoprotein VI stimulation in comparison to Protease-Activating Receptor (PAR) stimulation

Jinmi Zou, Jiayu Wu, Mark Roest, Johan W. M. Heemskerk

PLoS One. 2021; 16(3): e0247425. Published online 2021 Mar 3. doi: 10.1371/journal.pone.0247425

PMCID:: PMC7928515

Abstract Article PDF–2.3M

Select item 79015366.

GPVI (Glycoprotein VI) Interaction With Fibrinogen Is Mediated by Avidity and the Fibrinogen αC-Region

Rui-Gang Xu, Julia S. Gauer, Stephen R. Baker, Alexandre Slater, Eleyna M. Martin, Helen R. McPherson, Cédric Duval, Iain W. Manfield, Arkadiusz M. Bonna, Steve P. Watson, Robert A.S. Ariëns

Arterioscler Thromb Vasc Biol. 2021 Mar; 41(3): 1092–1104. Published online 2021 Jan 21. doi: 10.1161/ATVBAHA.120.315030

PMCID:: PMC7901536

Abstract Article PDF–2.8M

Select item 74643597.

Association between Platelet-Specific Collagen Receptor Glycoprotein 6 Gene Variants, Selected Biomarkers, and Recurrent Pregnancy Loss in Korean Women

Hui Jeong An, Eun Hee Ahn, Jung Oh Kim, Chang Soo Ryu, Han Sung Park, Sung Hwan Cho, Ji Hyang Kim, Woo Sik Lee, Jung Ryeol Lee, Young Ran Kim, Nam Keun Kim

Genes (Basel) 2020 Aug; 11(8): 862. Published online 2020 Jul 29. doi: 10.3390/genes11080862

PMCID:: PMC7464359

Abstract Article PDF–695K

Select item 73623458.

Flow studies on human GPVI-deficient blood under coagulating and noncoagulating conditions

Magdolna Nagy, Gina Perrella, Amanda Dalby, M. Francisca Becerra, Lourdes Garcia Quintanilla, Jeremy A. Pike, Neil V. Morgan, Elizabeth E. Gardiner, Johan W. M. Heemskerk, Lorena Azócar, Juan Francisco Miquel, Diego Mezzano, Steve P. Watson

Blood Adv. 2020 Jul 14; 4(13): 2953–2961. Published online 2020 Jun 30. doi: 10.1182/bloodadvances.2020001761

PMCID:: PMC7362345

Abstract Article PDF–1.5M

Select item 73276379.

Genetic variation of platelet glycoprotein VI and the risk of venous thromboembolism

Hanne Skille, Benedikte Paulsen, Kristian Hveem, Maiken E. Gabrielsen, Ben Brumpton, Kristian Hindberg, Olga V. Gran, Frits R. Rosendaal, Sigrid K. Brækkan, John-Bjarne Hansen

Haematologica. 2020 Jul; 105(7): e358–e360. doi: 10.3324/haematol.2019.231225

PMCID:: PMC7327637

Article PDF–479K

Select item 679861610.

Aspirin & clopidogrel non-responsiveness & its association with genetic polymorphisms in patients with myocardial infarction

Chandra Prakash Pandey, Ankita Misra, Mahendra Pal Singh Negi, Babu Nageswararao Kanuri, Yashpal Singh Chhonker, Rabi Shanker Bhatta, Varun Shanker Narain, Madhu Dikshit

Indian J Med Res. 2019 Jul; 150(1): 50–61. doi: 10.4103/ijmr.IJMR_782_17

PMCID:: PMC6798616

Abstract Article PDF–1.2M

Select item 671483511.

Glycoprotein VI Gene Variants Affect Pregnancy Loss in Patients With Platelet Hyperaggregability

Juraj Sokol, Maria Skerenova, Kamil Biringer, Tomas Simurda, Peter Kubisz, Jan Stasko

Clin Appl Thromb Hemost. 2018 Dec; 24(9 Suppl): 202S–208S. Published online 2018 Oct 2. doi: 10.1177/1076029618802358

PMCID:: PMC6714835

Abstract Article PDF–165K

Select item 671463212.

GP6 Haplotype of Missense Variants is Associated with Sticky Platelet Syndrome Manifested by Fetal Loss

Mária Škereňová, Juraj Sokol, Kamil Biringer, Jela Ivanková, Ján Staško, Peter Kubisz, Zora Lasabová

Clin Appl Thromb Hemost. 2018 Jan; 24(1): 63–69. Published online 2017 Jan 2. doi: 10.1177/1076029616685428

PMCID:: PMC6714632

Abstract Article PDF–178K

Select item 640345113.

GPVI surface expression and signalling pathway activation are increased in platelets from obese patients: Elucidating potential anti-atherothrombotic targets in obesity

María N. Barrachina, Aurelio M. Sueiro, Irene Izquierdo, Lidia Hermida-Nogueira, Esteban Guitián, Felipe F. Casanueva, Richard W. Farndale, Masaaki Moroi, Stephanie M. Jung, María Pardo, Ángel García

Atherosclerosis. 2019 Feb; 281: 62–70. doi: 10.1016/j.atherosclerosis.2018.12.023

PMCID:: PMC6403451

Abstract Article PDF–4.2M

Select item 632771614.

Human Platelet Protein Ubiquitylation and Changes following GPVI Activation

Amanda J. Unsworth, Izabela Bombik, Adan Pinto-Fernandez, Joanna F. McGouran, Rebecca Konietzny, René P. Zahedi, Steve P. Watson, Benedikt M. Kessler, Catherine J. Pears

Thromb Haemost. 2019 Jan; 119(1): 104–116. Published online 2018 Dec 31. doi: 10.1055/s-0038-1676344

PMCID:: PMC6327716

Abstract Article PDF–651K

Select item 630793615.

Functional significance of the platelet immune receptors GPVI and CLEC-2

Julie Rayes, Steve P. Watson, Bernhard Nieswandt

J Clin Invest. 2019 Jan 2; 129(1): 12–23. Published online 2019 Jan 2. doi: 10.1172/JCI122955

PMCID:: PMC6307936

Abstract Article PDF–8.4M

Select item 616668216.

Histone Interaction Landscapes Visualized by Crosslinking Mass Spectrometry in Intact Cell Nuclei

Domenico Fasci, Hugo van Ingen, Richard A. Scheltema, Albert J. R. Heck

Mol Cell Proteomics. 2018 Oct; 17(10): 2018–2033. Published online 2018 Jul 18. doi: 10.1074/mcp.RA118.000924

PMCID:: PMC6166682

Abstract Article PDF–3.8M

Select item 592076517.

Platelets drive thrombus propagation in a hematocrit and glycoprotein VI dependent manner in an in vitro venous thrombosis model

Marcus Lehmann, Rogier M. Schoeman, Patrick J. Krohl, Alison M. Wallbank, Joseph R. Samaniuk, Martine Jandrot-Perrus, Keith B. Neeves

Arterioscler Thromb Vasc Biol. Author manuscript; available in PMC 2019 May 1.

Published in final edited form as: Arterioscler Thromb Vasc Biol. 2018 May; 38(5): 1052–1062. Published online 2018 Feb 22. doi: 10.1161/ATVBAHA.118.310731

PMCID:: PMC5920765

Abstract Article PDF–1.6M

Select item 583880118.

Platelet collagen receptor Glycoprotein VI‐dimer recognizes fibrinogen and fibrin through their D‐domains, contributing to platelet adhesion and activation during thrombus formation

I. Induruwa, M. Moroi, A. Bonna, J.‐D. Malcor, J.‐M. Howes, E. A. Warburton, R. W. Farndale, S. M. Jung

J Thromb Haemost. 2018 Feb; 16(2): 389–404. Published online 2018 Jan 15. doi: 10.1111/jth.13919

PMCID:: PMC5838801

Abstract Article PDF–1.9M

Select item 581232219.

Soluble GPVI is elevated in injured patients: shedding is mediated by fibrin activation of GPVI

Samantha J. Montague, Céline Delierneux, Christelle Lecut, Nathalie Layios, Robert J. Dinsdale, Christine S.-M. Lee, Natalie S. Poulter, Robert K. Andrews, Peter Hampson, Christopher M. Wearn, Nathalie Maes, Jonathan Bishop, Amy Bamford, Chris Gardiner, Woei Ming Lee, Tariq Iqbal, Naiem Moiemen, Steve P. Watson, Cécile Oury, Paul Harrison, Elizabeth E. Gardiner

Blood Adv. 2018 Feb 13; 2(3): 240–251. Published online 2018 Feb 1. doi: 10.1182/bloodadvances.2017011171

PMCID:: PMC5812322

Abstract Article PDF–1.2M

Select item 563060020.

Mammalian APE1 controls miRNA processing and its interactome is linked to cancer RNA metabolism

Giulia Antoniali, Fabrizio Serra, Lisa Lirussi, Mikiei Tanaka, Chiara D’Ambrosio, Shiheng Zhang, Slobodanka Radovic, Emiliano Dalla, Yari Ciani, Andrea Scaloni, Mengxia Li, Silvano Piazza, Gianluca Tell

Nat Commun. 2017; 8: 797. Published online 2017 Oct 6. doi: 10.1038/s41467-017-00842-8

PMCID:: PMC5630600

Abstract Article PDF–2.3M

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