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Select item 108256301.

Low Plasma Gelsolin Concentrations in Chronic Granulomatous Disease

John Audley, Emily F. Gliniewicz, Kol A. Zarember, Hanna S. Hong, Gal Wald, Douglas B. Kuhns, Elizabeth Kang, Harry L. Malech, Anthony F. Suffredini, Robert J. Noveck, Mark J. Dinubile, Susan L. Levinson, Thomas P. Stossel, John I. Gallin

Inflammation. Author manuscript; available in PMC 2024 Jan 30.

Published in final edited form as: Inflammation. 2021 Feb; 44(1): 270–277. Published online 2020 Sep 4. doi: 10.1007/s10753-020-01330-w

PMCID:: PMC10825630

Abstract Article PDF–788K

Select item 107854802.

The regulation of plasma gelsolin by DNA methylation in ovarian cancer chemo-resistance

Hafiza Bushra Manzoor, Meshach Asare-Werehene, Satyajit Dey Pereira, Kapaettu Satyamoorthy, Benjamin K. Tsang

J Ovarian Res. 2024; 17: 15. Published online 2024 Jan 12. doi: 10.1186/s13048-023-01332-w

PMCID:: PMC10785480

Abstract Article PDF–3.5M

Select item 106475093.

Gelsolin, an Actin-Binding Protein: Bioinformatic Analysis and Functional Significance in Urothelial Bladder Carcinoma

Abeer A. Alsofyani, Taoufik Nedjadi

Int J Mol Sci. 2023 Nov; 24(21): 15763. Published online 2023 Oct 30. doi: 10.3390/ijms242115763

PMCID:: PMC10647509

Abstract Article PDF–8.7M

Select item 103232524.

Proximity labelling identifies pro-migratory endocytic recycling cargo and machinery of the Rab4 and Rab11 families

Beverley Wilson, Chloe Flett, Jakub Gemperle, Craig Lawless, Matthew Hartshorn, Eleanor Hinde, Tess Harrison, Megan Chastney, Sarah Taylor, Jennifer Allen, Jim C. Norman, Thomas Zacharchenko, Patrick T. Caswell

J Cell Sci. 2023 Jun 15; 136(12): jcs260468. Published online 2023 Jun 23. doi: 10.1242/jcs.260468

PMCID:: PMC10323252

Abstract Article

Select item 103140705.

GSN gene frameshift mutations in Alzheimer’s disease

Yaling Jiang, Meidan Wan, XueWen Xiao, Zhuojie Lin, Xixi Liu, Yafang Zhou, Xinxin Liao, Jingyi Lin, Hui Zhou, Lu Zhou, Ling Weng, Junling Wang, Jifeng Guo, Hong Jiang, Zhuohua Zhang, Kun Xia, Jiada Li, Beisha Tang, Bin Jiao, Lu Shen

J Neurol Neurosurg Psychiatry. 2023 Jun; 94(6): 436–447. Published online 2023 Jan 17. doi: 10.1136/jnnp-2022-330465

PMCID:: PMC10314070

Abstract Article PDF–8.6M

Select item 102374226.

TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan

Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233

PMCID:: PMC10237422

Abstract Article PDF–23M

Select item 101645647.

The ubiquitin-specific protease USP36 SUMOylates EXOSC10 and promotes the nucleolar RNA exosome function in rRNA processing

Yingxiao Chen, Yanping Li, Roselyn S Dai, Jonathan C Savage, Ujwal Shinde, John Klimek, Larry L David, Emma A Young, Markus Hafner, Rosalie C Sears, Xiao-Xin Sun, Mu-Shui Dai

Nucleic Acids Res. 2023 May 8; 51(8): 3934–3949. Published online 2023 Mar 13. doi: 10.1093/nar/gkad140

PMCID:: PMC10164564

Abstract Article PDF–3.8M

Select item 101488438.

mTORC2 interactome and localization determine aggressiveness of high-grade glioma cells through association with gelsolin

Naphat Chantaravisoot, Piriya Wongkongkathep, Nuttiya Kalpongnukul, Narawit Pacharakullanon, Pornchai Kaewsapsak, Chaiyaboot Ariyachet, Joseph A. Loo, Fuyuhiko Tamanoi, Trairak Pisitkun

Sci Rep. 2023; 13: 7037. Published online 2023 Apr 29. doi: 10.1038/s41598-023-33872-y

PMCID:: PMC10148843

Abstract Article PDF–11M

Select item 101122819.

TNIP1 inhibits selective autophagy via bipartite interaction with LC3/GABARAP and TAX1BP1

François Le Guerroué, Eric N Bunker, William M Rosencrans, Jack T Nguyen, Mohammed A Basar, Achim Werner, Tsui-Fen Chou, Chunxin Wang, Richard J Youle

Mol Cell. Author manuscript; available in PMC 2024 Mar 16.

Published in final edited form as: Mol Cell. 2023 Mar 16; 83(6): 927–941.e8. Published online 2023 Mar 9. doi: 10.1016/j.molcel.2023.02.023

PMCID:: PMC10112281

Abstract Article PDF–2.4M

Select item 1002663810.

Fusion of the High-mobility Group AT-Hook 2 (HMGA2) and the Gelsolin (GSN) Genes in Lipomas With t(9;12)(q33;q14) Chromosomal Translocation

IOANNIS PANAGOPOULOS, KRISTIN ANDERSEN, MARTA BRUNETTI, LUDMILA GORUNOVA, MARIUS LUND-IVERSEN, FRANCESCA MICCI, SVERRE HEIM

In Vivo. 2023 Mar-Apr; 37(2): 524–530. Published online 2023 Mar 3. doi: 10.21873/invivo.13110

PMCID:: PMC10026638

Abstract Article PDF–2.2M

Select item 997298211.

HIV-1 Vpr Induces Degradation of Gelsolin, a Myeloid Cell-Specific Host Factor That Reduces Viral Infectivity by Inhibiting the Expression and Packaging of the HIV-1 Env Glycoprotein

Helena Fabryova, Sandra Kao, Sayaka Sukegawa, Eri Miyagi, Louis Taylor, Damien Ferhadian, Hideki Saito, Heiner Schaal, Frank Hillebrand, Klaus Strebel

mBio. 2023 Jan-Feb; 14(1): e02973-22. Published online 2023 Jan 5. doi: 10.1128/mbio.02973-22

PMCID:: PMC9972982

Abstract Article PDF–2.6M

Select item 995044712.

Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma

Yu-Fei Cao, Lei Xie, Bei-Bei Tong, Man-Yu Chu, Wen-Qi Shi, Xiang Li, Jian-Zhong He, Shao-Hong Wang, Zhi-Yong Wu, Dan-Xia Deng, Ya-Qi Zheng, Zhi-Mao Li, Xiu-E Xu, Lian-Di Liao, Yin-Wei Cheng, Li-Yan Li, Li-Yan Xu, En-Min Li

Cell Death Differ. 2023 Feb; 30(2): 527–543. Published online 2022 Dec 16. doi: 10.1038/s41418-022-01104-x

PMCID:: PMC9950447

Abstract Article PDF–8.4M

Select item 979798813.

TBK1 posphorylation activates LIR-dependent degradation of the inflammation repressor TNIP1

Jianwen Zhou, Nikoline Lander Rasmussen, Hallvard Lauritz Olsvik, Vyacheslav Akimov, Zehan Hu, Gry Evjen, Stéphanie Kaeser-Pebernard, Devanarayanan Siva Sankar, Carole Roubaty, Pauline Verlhac, Nicole van de Beek, Fulvio Reggiori, Yakubu Princely Abudu, Blagoy Blagoev, Trond Lamark, Terje Johansen, Jörn Dengjel

J Cell Biol. 2023 Feb 6; 222(2): e202108144. Published online 2022 Dec 27. doi: 10.1083/jcb.202108144

PMCID:: PMC9797988

Abstract Article PDF–6.9M

Select item 960054514.

Exosomal Plasma Gelsolin Is an Immunosuppressive Mediator in the Ovarian Tumor Microenvironment and a Determinant of Chemoresistance

Toshimichi Onuma, Meshach Asare-Werehene, Yoshio Yoshida, Benjamin K. Tsang

Cells. 2022 Oct; 11(20): 3305. Published online 2022 Oct 20. doi: 10.3390/cells11203305

PMCID:: PMC9600545

Abstract Article PDF–1.6M

Select item 956995515.

A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation

Yulemi Gonzalez Quesada, Luc DesGroseillers

Int J Mol Sci. 2022 Oct; 23(19): 11588. Published online 2022 Sep 30. doi: 10.3390/ijms231911588

PMCID:: PMC9569955

Abstract Article PDF–2.1M

Select item 948511916.

CAF-derived exosomal WEE2-AS1 facilitates colorectal cancer progression via promoting degradation of MOB1A to inhibit the Hippo pathway

Peng Yang, Dongsheng Zhang, Tuo Wang, Jiangzhou Ji, Chi Jin, Chaofan Peng, Yuqian Tan, Jiahui Zhou, Lu Wang, Yifei Feng, Yueming Sun

Cell Death Dis. 2022 Sep; 13(9): 796. Published online 2022 Sep 19. doi: 10.1038/s41419-022-05240-7

PMCID:: PMC9485119

Abstract Article PDF–8.2M

Select item 947546217.

ARHGAP24 represses β-catenin transactivation-induced invasiveness in hepatocellular carcinoma mainly by acting as a GTPase-independent scaffold

Wenjing Yang, Beili Wang, Qian Yu, Te Liu, Tong Li, Tongtong Tian, Anli Jin, Lin Ding, Wei Chen, Hao Wang, Jingrong Xian, Baishen Pan, Jian Zhou, Jia Fan, Xinrong Yang, Wei Guo

Theranostics. 2022; 12(14): 6189–6206. Published online 2022 Aug 21. doi: 10.7150/thno.72134

PMCID:: PMC9475462

Abstract Article PDF–4.6M

Select item 936342718.

The SWI/SNF chromatin remodeling factor DPF3 regulates metastasis of ccRCC by modulating TGF-β signaling

Huanhuan Cui, Hongyang Yi, Hongyu Bao, Ying Tan, Chi Tian, Xinyao Shi, Diwen Gan, Bin Zhang, Weizheng Liang, Rui Chen, Qionghua Zhu, Liang Fang, Xin Gao, Hongda Huang, Ruijun Tian, Silke R. Sperling, Yuhui Hu, Wei Chen

Nat Commun. 2022; 13: 4680. Published online 2022 Aug 9. doi: 10.1038/s41467-022-32472-0

PMCID:: PMC9363427

Abstract Article PDF–3.6M

Select item 929024119.

Combinatorial targeting of a chromatin complex comprising Dot1L, menin and the tyrosine kinase BAZ1B reveals a new therapeutic vulnerability of endocrine therapy-resistant breast cancer

Annamaria Salvati, Viola Melone, Assunta Sellitto, Francesca Rizzo, Roberta Tarallo, Tuula A. Nyman, Giorgio Giurato, Giovanni Nassa, Alessandro Weisz

Breast Cancer Res. 2022; 24: 52. Published online 2022 Jul 18. doi: 10.1186/s13058-022-01547-7