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Select item 93010821.

KCC3a, a Strong Candidate Pathway for K⁺ Loss in Alkalemia

Mohammed Zubaerul Ferdaus, Andrew Scott Terker, Rainelli Koumangoye, Eric Delpire

Front Cell Dev Biol. 2022; 10: 931326. Published online 2022 Jul 7. doi: 10.3389/fcell.2022.931326

PMCID:: PMC9301082

Abstract Article PDF–2.7M

Select item 89151592.

Erythroid‐specific inactivation of Slc12a6/Kcc3 by EpoR promoter‐driven Cre expression reduces K‐Cl cotransport activity in mouse erythrocytes

Boris E. Shmukler, Alicia Rivera, Katherine Nishimura, Ann Hsu, Jay G. Wohlgemuth, Jeffrey S. Dlott, L. Michael Snyder, Carlo Brugnara, Seth L. Alper

Physiol Rep. 2022 Mar; 10(5): e15186. Published online 2022 Mar 11. doi: 10.14814/phy2.15186

PMCID:: PMC8915159

Abstract Article PDF–1.1M

Select item 86314243.

WNK3 Maintains the GABAergic Inhibitory Tone, Synaptic Excitation and Neuronal Excitability via Regulation of KCC2 Cotransporter in Mature Neurons

Wee Meng Lim, Eunice W. M. Chin, Bor Luen Tang, Tingting Chen, Eyleen L. K. Goh

Front Mol Neurosci. 2021; 14: 762142. Published online 2021 Nov 10. doi: 10.3389/fnmol.2021.762142

PMCID:: PMC8631424

Abstract Article PDF–6.0M

Select item 81635754.

Temporal manipulation of KCC3 expression in juvenile or adult mice suggests irreversible developmental deficit in hereditary motor sensory neuropathy with agenesis of the corpus callosum

Bianca Flores, Eric Delpire

Am J Physiol Cell Physiol. 2021 May 1; 320(5): C722–C730. Published online 2021 Feb 17. doi: 10.1152/ajpcell.00594.2020

PMCID:: PMC8163575

Abstract Article

Select item 74159915.

BioID screening of biotinylation sites using the avidin-like protein Tamavidin 2-REV identifies global interactors of stimulator of interferon genes (STING)

Kou Motani, Hidetaka Kosako

J Biol Chem. 2020 Aug 7; 295(32): 11174–11183. Published online 2020 Jun 17. doi: 10.1074/jbc.RA120.014323

PMCID:: PMC7415991

Abstract Article PDF–2.0M

Select item 73936356.

Osmotic Response of Dorsal Root Ganglion Neurons Expressing Wild-Type and Mutant KCC3 Transporters

Bianca Flores, Eric Delpire

Cell Physiol Biochem. Author manuscript; available in PMC 2021 Jun 8.

Published in final edited form as: Cell Physiol Biochem. 2020 Jun 8; 54(4): 577–590. doi: 10.33594/000000241

PMCID:: PMC7393635

Abstract Article PDF–1.2M

Select item 70022947.

Genetic disruption of KCC cotransporters in a mouse model of thalassemia intermedia.

Boris E. Shmukler, Alicia Rivera, Parul Bhargava, Katherine Nishimura, Edward H. Kim, Ann Hsu, Jay G. Wohlgemuth, James Morton, L. Michael Snyder, Lucia De Franceschi, Marco B. Rust, Christian A. Hubner, Carlo Brugnara, Seth L. Alper

Blood Cells Mol Dis. Author manuscript; available in PMC 2021 Mar 1.

Published in final edited form as: Blood Cells Mol Dis. 2020 Mar; 81: 102389. Published online 2019 Nov 25. doi: 10.1016/j.bcmd.2019.102389

PMCID:: PMC7002294

Abstract Article PDF–2.4M

Select item 67442918.

Combined genetic disruption of K-Cl cotransporters and Gardos channel KCNN4 rescues erythrocyte dehydration in the SAD mouse model of sickle cell disease.

Boris E. Shmukler, Alicia Rivera, Parul Bhargava, Katherine Nishimura, Ann Hsu, Edward H. Kim, Marie Trudel, Marco B. Rust, Christian A. Hubner, Carlo Brugnara, Seth L. Alper

Blood Cells Mol Dis. Author manuscript; available in PMC 2020 Nov 1.

Published in final edited form as: Blood Cells Mol Dis. 2019 Nov; 79: 102346. Published online 2019 Jul 17. doi: 10.1016/j.bcmd.2019.102346

Correction in:: Blood Cells Mol Dis. 2020 Jan 10; 81: 102390.

PMCID:: PMC6744291

Abstract Article PDF–1.4M

Select item 67034519.

Loss of Neuronal Potassium/Chloride Cotransporter 3 (KCC3) Is Responsible for the Degenerative Phenotype in a Conditional Mouse Model of Hereditary Motor and Sensory Neuropathy Associated with Agenesis of the Corpus Callosum

Masoud Shekarabi, Randal X. Moldrich, Sarah Rasheed, Adéle Salin-Cantegrel, Janet Laganière, Daniel Rochefort, Pascale Hince, Karine Huot, Rébecca Gaudet, Nyoman Kurniawan, Susana G. Sotocinal, Jennifer Ritchie, Patrick A. Dion, Jeffrey S. Mogil, Linda J. Richards, Guy A. Rouleau

J Neurosci. 2012 Mar 14; 32(11): 3865–3876. doi: 10.1523/JNEUROSCI.3679-11.2012

PMCID:: PMC6703451

Abstract Article PDF–4.0M

Select item 550649310.

Peripheral motor neuropathy is associated with defective kinase regulation of the KCC3 cotransporter

Kristopher T. Kahle, Bianca Flores, Diana Bharucha-Goebel, Jinwei Zhang, Sandra Donkervoort, Madhuri Hegde, Gulnaz Begum, Daniel Duran, Bo Liang, Dandan Sun, Carsten G. Bönnemann, Eric Delpire

Sci Signal. Author manuscript; available in PMC 2017 Aug 2.

Published in final edited form as: Sci Signal. 2016 Aug 2; 9(439): ra77. Published online 2016 Aug 2. doi: 10.1126/scisignal.aae0546

PMCID:: PMC5506493

Abstract Article PDF–1013K

Select item 508061411.

Functional kinomics establishes a critical node of volume-sensitive cation-Cl⁻ cotransporter regulation in the mammalian brain

Jinwei Zhang, Geng Gao, Gulnaz Begum, Jinhua Wang, Arjun R. Khanna, Boris E. Shmukler, Gerrit M. Daubner, Paola de los Heros, Paul Davies, Joby Varghese, Mohammad Iqbal H. Bhuiyan, Jinjing Duan, Jin Zhang, Daniel Duran, Seth L. Alper, Dandan Sun, Stephen J. Elledge, Dario R. Alessi, Kristopher T. Kahle

Sci Rep. 2016; 6: 35986. Published online 2016 Oct 26. doi: 10.1038/srep35986

PMCID:: PMC5080614

Abstract Article PDF–2.9M

Select item 486429612.

Ablation of Potassium-Chloride Cotransporter Type 3 (Kcc3) in Mouse Causes Multiple Cardiovascular Defects and Isosmotic Polyuria

Alexandre P. Garneau, Andrée-Anne Marcoux, Micheline Noël, Rachelle Frenette-Cotton, Marie-Claude Drolet, Jacques Couet, Richard Larivière, Paul Isenring

PLoS One. 2016; 11(5): e0154398. Published online 2016 May 11. doi: 10.1371/journal.pone.0154398

PMCID:: PMC4864296

Abstract Article PDF–24M

Select item 417997213.

Deletion of KCC3 in parvalbumin neurons leads to locomotor deficit in a conditional mouse model of peripheral neuropathy associated with agenesis of the corpus callosum

Jinlong Ding, Eric Delpire

Behav Brain Res. Author manuscript; available in PMC 2015 Nov 1.

Published in final edited form as: Behav Brain Res. 2014 Nov 1; 0: 128–136. Published online 2014 Aug 10. doi: 10.1016/j.bbr.2014.08.005

PMCID:: PMC4179972

Abstract Article PDF–2.7M

Select item 384025314.

Molecular evidence for a role for K⁺-Cl⁻ cotransporters in the kidney

Zesergio Melo, Silvia Cruz-Rangel, Rocio Bautista, Norma Vázquez, María Castañeda-Bueno, David B. Mount, Herminia Pasantes-Morales, Adriana Mercado, Gerardo Gamba

Am J Physiol Renal Physiol. 2013 Nov 15; 305(10): F1402–F1411. Published online 2013 Oct 2. doi: 10.1152/ajprenal.00390.2013

PMCID:: PMC3840253

Abstract Article

Select item 361723215.

A Trafficking-Deficient Mutant of KCC3 Reveals Dominant-Negative Effects on K–Cl Cotransport Function

Jinlong Ding, José Ponce-Coria, Eric Delpire

PLoS One. 2013; 8(4): e61112. Published online 2013 Apr 4. doi: 10.1371/journal.pone.0061112

PMCID:: PMC3617232

Abstract Article PDF–942K

Select item 357241016.

A conditional knockout resource for the genome–wide study of mouse gene function

William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley

Nature. Author manuscript; available in PMC 2013 Feb 14.

Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163

PMCID:: PMC3572410

Abstract Article PDF–1.1M

Select item 345903917.

K⁺–Cl⁻ cotransport mediates the bactericidal activity of neutrophils by regulating NADPH oxidase activation

Yuan-Ting Sun, Chi-Chang Shieh, Eric Delpire, Meng-Ru Shen

J Physiol. 2012 Jul 15; 590(Pt 14): 3231–3243. Published online 2012 Apr 23. doi: 10.1113/jphysiol.2011.225300

PMCID:: PMC3459039

Abstract Article PDF–1.7M

Select item 343226418.

Network Organization of the Huntingtin Proteomic Interactome in Mammalian Brain

Dyna I. Shirasaki, Erin R. Greiner, Ismael Al-Ramahi, Michelle Gray, Pinmanee Boontheung, Daniel H. Geschwind, Juan Botas, Giovanni Coppola, Steve Horvath, Joseph A. Loo, X. William Yang

Neuron. Author manuscript; available in PMC 2013 Jul 12.

Published in final edited form as: Neuron. 2012 Jul 12; 75(1): 41–57. doi: 10.1016/j.neuron.2012.05.024

PMCID:: PMC3432264

Abstract Article PDF–4.9M

Select item 329799519.

Raising cytosolic Cl⁻ in cerebellar granule cells affects their excitability and vestibulo-ocular learning

Patricia Seja, Martijn Schonewille, Guillermo Spitzmaul, Aleksandra Badura, Ilse Klein, York Rudhard, William Wisden, Christian A Hübner, Chris I De Zeeuw, Thomas J Jentsch

EMBO J. 2012 Mar 7; 31(5): 1217–1230. Published online 2012 Jan 17. doi: 10.1038/emboj.2011.488

PMCID:: PMC3297995

Abstract Article PDF–2.6M

Select item 317805920.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

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