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Items: 1 to 20 of 30

1.
Regulation of meiotic telomere dynamics through membrane fluidity promoted by AdipoR2-ELOVL2
Jingjing Zhang, Mario Ruiz, Per-Olof Bergh, Marcus Henricsson, Nena Stojanović, Ranjan Devkota, Marius Henn, Mohammad Bohlooly-Y, Abrahan Hernández-Hernández, Manfred Alsheimer, Jan Borén, Marc Pilon, Hiroki Shibuya
Nat Commun. 2024; 15: 2315. Published online 2024 Mar 14. doi: 10.1038/s41467-024-46718-6
PMCID:
PMC10940294
AbstractArticlePDF–6.0M
2.
Spinocerebellar ataxia 38: structure–function analysis shows ELOVL5 G230V is proteotoxic, conformationally altered and a mutational hotspot
Enza Ferrero, Eleonora Di Gregorio, Marta Ferrero, Erika Ortolan, Young-Ah Moon, Antonella Di Campli, Lisa Pavinato, Cecilia Mancini, Debasmita Tripathy, Marta Manes, Eriola Hoxha, Chiara Costanzi, Elisa Pozzi, Matteo Rossi Sebastiano, Nico Mitro, Filippo Tempia, Donatella Caruso, Barbara Borroni, Manuela Basso, Michele Sallese, Alfredo Brusco
Hum Genet. 2023; 142(8): 1055–1076. Published online 2023 May 18. doi: 10.1007/s00439-023-02572-y
PMCID:
PMC10449689
AbstractArticlePDF–5.4M
3.
Downregulation of Elovl5 promotes breast cancer metastasis through a lipid-droplet accumulation-mediated induction of TGF-β receptors
Trinh-Le-Vi Kieu, Léa Pierre, Valentin Derangère, Sabrina Perrey, Caroline Truntzer, Antoine Jalil, Sébastien Causse, Emma Groetz, Adélie Dumont, Laura Guyard, Laurent Arnould, Jean-Paul Pais de Barros, Lionel Apetoh, Cédric Rébé, Emeric Limagne, Tony Jourdan, Laurent Demizieux, David Masson, Charles Thomas, François Ghiringhelli, Mickaël Rialland
Cell Death Dis. 2022 Sep; 13(9): 758. Published online 2022 Sep 2. doi: 10.1038/s41419-022-05209-6
PMCID:
PMC9440092
AbstractArticlePDF–5.9M
4.
Effects of the administration of Elovl5-dependent fatty acids on a spino-cerebellar ataxia 38 mouse model
Ilaria Balbo, Francesca Montarolo, Federica Genovese, Filippo Tempia, Eriola Hoxha
Behav Brain Funct. 2022; 18: 8. Published online 2022 Aug 6. doi: 10.1186/s12993-022-00194-4
PMCID:
PMC9357323
AbstractArticlePDF–1.4M
5.
Loss of zinc-finger protein 212 leads to Purkinje cell death and locomotive abnormalities with phospholipase D3 downregulation
Rin Khang, Areum Jo, Hojin Kang, Hanna Kim, Eunsang Kwag, Ji-Yeong Lee, Okjae Koo, Jinsu Park, Hark Kyun Kim, Dong-Gyu Jo, Inwoo Hwang, Jee-Yin Ahn, Yunjong Lee, Jeong-Yun Choi, Yun-Song Lee, Joo-Ho Shin
Sci Rep. 2021; 11: 22745. Published online 2021 Nov 23. doi: 10.1038/s41598-021-02218-x
PMCID:
PMC8610974
AbstractArticlePDF–2.5M
6.
Elovl5 is required for proper action potential conduction along peripheral myelinated fibers
Eriola Hoxha, Ilaria Balbo, Roberta Parolisi, Matteo Audano, Francesca Montarolo, Francesco Ravera, Michela Guglielmotto, Luisa Muratori, Stefania Raimondo, Eleonora DiGregorio, Annalisa Buffo, Alfredo Brusco, Barbara Borroni, Nico Mitro, Donatella Caruso, Filippo Tempia
Glia. 2021 Oct; 69(10): 2419–2428. Published online 2021 Jun 17. doi: 10.1002/glia.24048
PMCID:
PMC8453547
AbstractArticlePDF–3.3M
7.
BioID screening of biotinylation sites using the avidin-like protein Tamavidin 2-REV identifies global interactors of stimulator of interferon genes (STING)
Kou Motani, Hidetaka Kosako
J Biol Chem. 2020 Aug 7; 295(32): 11174–11183. Published online 2020 Jun 17. doi: 10.1074/jbc.RA120.014323
PMCID:
PMC7415991
AbstractArticlePDF–2.0M
8.
Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors
Hyeonwoo Kim, Christiane D. Wrann, Mark Jedrychowski, Sara Vidoni, Yukiko Kitase, Kenichi Nagano, Chenhe Zhou, Joshua Chou, Virginia-Jeni A. Parkman, Scott J. Novick, Timothy S. Strutzenberg, Bruce D. Pascal, Phuong T. Le, Daniel J. Brooks, Alexander M. Roche, Kaitlyn K. Gerber, Laura Mattheis, Wenjing Chen, Hua Tu, Mary L. Bouxsein, Patrick R. Griffin, Roland Baron, Clifford J. Rosen, Lynda F. Bonewald, Bruce M. Spiegelman
Cell. Author manuscript; available in PMC 2019 Dec 13.
Published in final edited form as: Cell. 2018 Dec 13; 175(7): 1756–1768.e17. doi: 10.1016/j.cell.2018.10.025
Correction in:
Cell. 2019 Jul 11; 178(2): 507–508.
PMCID:
PMC6298040
AbstractArticlePDF–1.2M
9.
Genome-wide methylation analysis identifies ELOVL5 as an epigenetic biomarker for the risk of type 2 diabetes mellitus
Joo-Yeon Hwang, Hyo Jung Lee, Min Jin Go, Han Byul Jang, Nak-Hyun Choi, Jae Bum Bae, Juan E. Castillo-Fernandez, Jordana T. Bell, Tim D. Spector, Hye-Ja Lee, Bong-Jo Kim
Sci Rep. 2018; 8: 14862. Published online 2018 Oct 5. doi: 10.1038/s41598-018-33238-9
PMCID:
PMC6173741
AbstractArticlePDF–1.4M
10.
Motor Deficits and Cerebellar Atrophy in Elovl5 Knock Out Mice
Eriola Hoxha, Rebecca M. C. Gabriele, Ilaria Balbo, Francesco Ravera, Linda Masante, Vanessa Zambelli, Cristian Albergo, Nico Mitro, Donatella Caruso, Eleonora Di Gregorio, Alfredo Brusco, Barbara Borroni, Filippo Tempia
Front Cell Neurosci. 2017; 11: 343. Published online 2017 Oct 30. doi: 10.3389/fncel.2017.00343
PMCID:
PMC5670146
AbstractArticlePDF–4.9M
11.
The antiobesity factor WDTC1 suppresses adipogenesis via the CRL4WDTC1 E3 ligase
Beezly S Groh, Feng Yan, Matthew D Smith, Yanbao Yu, Xian Chen, Yue Xiong
EMBO Rep. 2016 May; 17(5): 638–647. Published online 2016 Apr 9. doi: 10.15252/embr.201540500
PMCID:
PMC5341520
AbstractArticlePDF–1.1M
12.
Fatty acid elongase-5 (Elovl5) regulates hepatic triglyceride catabolism in obese C57BL/6J mice
Sasmita Tripathy, Kelli A. Lytle, Robert D. Stevens, James R. Bain, Christopher B. Newgard, Andrew S. Greenberg, Li-Shin Huang, Donald B. Jump
J Lipid Res. 2014 Jul; 55(7): 1448–1464. doi: 10.1194/jlr.M050062
PMCID:
PMC4076069
AbstractArticlePDF–1.6M
13.
Impaired Epidermal Permeability Barrier in Mice Lacking Elovl1, the Gene Responsible for Very-Long-Chain Fatty Acid Production
Takayuki Sassa, Yusuke Ohno, Shotaro Suzuki, Toshifumi Nomura, Chieko Nishioka, Toshiki Kashiwagi, Taisuke Hirayama, Masashi Akiyama, Ryo Taguchi, Hiroshi Shimizu, Shigeyoshi Itohara, Akio Kihara
Mol Cell Biol. 2013 Jul; 33(14): 2787–2796. doi: 10.1128/MCB.00192-13
PMCID:
PMC3700134
AbstractArticlePDF–2.0M
14.
Elovl5 regulates the mTORC2-Akt-FOXO1 pathway by controlling hepatic cis-vaccenic acid synthesis in diet-induced obese mice
Sasmita Tripathy, Donald B. Jump
J Lipid Res. 2013 Jan; 54(1): 71–84. doi: 10.1194/jlr.M028787
PMCID:
PMC3520542
AbstractArticlePDF–1.8M
15.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
16.
A High-Resolution Anatomical Atlas of the Transcriptome in the Mouse Embryo
Graciana Diez-Roux, Sandro Banfi, Marc Sultan, Lars Geffers, Santosh Anand, David Rozado, Alon Magen, Elena Canidio, Massimiliano Pagani, Ivana Peluso, Nathalie Lin-Marq, Muriel Koch, Marchesa Bilio, Immacolata Cantiello, Roberta Verde, Cristian De Masi, Salvatore A. Bianchi, Juliette Cicchini, Elodie Perroud, Shprese Mehmeti, Emilie Dagand, Sabine Schrinner, Asja Nürnberger, Katja Schmidt, Katja Metz, Christina Zwingmann, Norbert Brieske, Cindy Springer, Ana Martinez Hernandez, Sarah Herzog, Frauke Grabbe, Cornelia Sieverding, Barbara Fischer, Kathrin Schrader, Maren Brockmeyer, Sarah Dettmer, Christin Helbig, Violaine Alunni, Marie-Annick Battaini, Carole Mura, Charlotte N. Henrichsen, Raquel Garcia-Lopez, Diego Echevarria, Eduardo Puelles, Elena Garcia-Calero, Stefan Kruse, Markus Uhr, Christine Kauck, Guangjie Feng, Nestor Milyaev, Chuang Kee Ong, Lalit Kumar, MeiSze Lam, Colin A. Semple, Attila Gyenesei, Stefan Mundlos, Uwe Radelof, Hans Lehrach, Paolo Sarmientos, Alexandre Reymond, Duncan R. Davidson, Pascal Dollé, Stylianos E. Antonarakis, Marie-Laure Yaspo, Salvador Martinez, Richard A. Baldock, Gregor Eichele, Andrea Ballabio
PLoS Biol. 2011 Jan; 9(1): e1000582. Published online 2011 Jan 18. doi: 10.1371/journal.pbio.1000582
PMCID:
PMC3022534
AbstractArticlePDF–3.8M
17.
Elevated hepatic fatty acid elongase-5 activity corrects dietary fat-induced hyperglycemia in obese BL/6J mice
Sasmita Tripathy, Moises Torres-Gonzalez, Donald B. Jump
J Lipid Res. 2010 Sep; 51(9): 2642–2654. doi: 10.1194/jlr.M006080
PMCID:
PMC2918446
AbstractArticlePDF–1.0M
18.
Deletion of ELOVL5 leads to fatty liver through activation of SREBP-1c in mice
Young-Ah Moon, Robert E. Hammer, Jay D. Horton
J Lipid Res. 2009 Mar; 50(3): 412–423. doi: 10.1194/jlr.M800383-JLR200
PMCID:
PMC2638104
AbstractArticlePDF–980K
19.
Large-scale gene trapping in C57BL/6N mouse embryonic stem cells
Gwenn M. Hansen, Diane C. Markesich, Michael B. Burnett, Qichao Zhu, Karen M. Dionne, Lizabeth J. Richter, Richard H. Finnell, Arthur T. Sands, Brian P. Zambrowicz, Alejandro Abuin
Genome Res. 2008 Oct; 18(10): 1670–1679. doi: 10.1101/gr.078352.108
PMCID:
PMC2556270
AbstractArticlePDF–493K
20.
Elevated hepatic fatty acid elongase-5 activity affects multiple pathways controlling hepatic lipid and carbohydrate composition
Yun Wang, Moises Torres-Gonzalez, Sasmita Tripathy, Daniela Botolin, Barbara Christian, Donald B. Jump
J Lipid Res. 2008 Jul; 49(7): 1538–1552. doi: 10.1194/jlr.M800123-JLR200
PMCID:
PMC2431109
AbstractArticlePDF–444K

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