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Select item 109176601.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 96409852.

Wnt signaling modulator DKK4 inhibits colorectal cancer metastasis through an AKT/Wnt/β-catenin negative feedback pathway

Junrong Liang, Lina Sun, Yujun Li, Wanning Liu, Danxiu Li, Ping Chen, Xin Wang, Juan Hui, Jinchi Zhou, Hao Liu, Tianyu Cao, Maogui Pang, Meng Guo, Xin Wang, Xiaodi Zhao, Yuanyuan Lu

J Biol Chem. 2022 Nov; 298(11): 102545. Published online 2022 Sep 29. doi: 10.1016/j.jbc.2022.102545

PMCID:: PMC9640985

Abstract Article PDF–4.7M

Select item 90381973.

AP-2α and AP-2β cooperatively function in the craniofacial surface ectoderm to regulate chromatin and gene expression dynamics during facial development

Eric Van Otterloo, Isaac Milanda, Hamish Pike, Jamie A Thompson, Hong Li, Kenneth L Jones, Trevor Williams

eLife. 2022; 11: e70511. Published online 2022 Mar 25. doi: 10.7554/eLife.70511

PMCID:: PMC9038197

Abstract Article PDF–16M

Select item 66023584.

The molecular anatomy of mammalian upper lip and primary palate fusion at single cell resolution

Hong Li, Kenneth L. Jones, Joan E. Hooper, Trevor Williams

Development. 2019 Jun 15; 146(12): dev174888. Published online 2019 Jun 17. doi: 10.1242/dev.174888

PMCID:: PMC6602358

Abstract Article

Select item 65178355.

Suppression of epithelial differentiation by Foxi3 is essential for molar crown patterning

Maria Jussila, Anne J. Aalto, Maria Sanz Navarro, Vera Shirokova, Anamaria Balic, Aki Kallonen, Takahiro Ohyama, Andrew K. Groves, Marja L. Mikkola, Irma Thesleff

Development. 2015 Nov 15; 142(22): 3954–3963. Published online 2015 Nov 17. doi: 10.1242/dev.124172

PMCID:: PMC6517835

Abstract Article

Select item 65143026.

Lrp4 and Wise interplay controls the formation and patterning of mammary and other skin appendage placodes by modulating Wnt signaling

Youngwook Ahn, Carrie Sims, Jennifer M. Logue, Scott D. Weatherbee, Robb Krumlauf

Development. 2013 Feb 1; 140(3): 583–593. Published online 2013 Jan 4. doi: 10.1242/dev.085118

PMCID:: PMC6514302

Abstract Article

Select item 63455177.

Regional Control of Hairless versus Hair-Bearing Skin by Dkk2

Yaolin Song, Ana C. Boncompagni, Sang-Seok Kim, Heather R. Gochnauer, Yuhang Zhang, Gabriela G. Loots, Dianqing Wu, Yulin Li, Mingang Xu, Sarah E. Millar

Cell Rep. Author manuscript; available in PMC 2019 Jan 24.

Published in final edited form as: Cell Rep. 2018 Dec 11; 25(11): 2981–2991.e3. Published online 2018 Nov 30. doi: 10.1016/j.celrep.2018.11.017

PMCID:: PMC6345517

Abstract Article PDF–1.9M

Select item 56138798.

Modulating Wnt Signaling Rescues Palate Morphogenesis in Pax9 Mutant Mice

C. Li, Y. Lan, R. Krumlauf, R. Jiang

J Dent Res. 2017 Oct; 96(11): 1273–1281. Published online 2017 Jul 10. doi: 10.1177/0022034517719865

PMCID:: PMC5613879

Abstract Article PDF–1.5M

Select item 55074059.

Hierarchical patterning modes orchestrate hair follicle morphogenesis

James D. Glover, Kirsty L. Wells, Franziska Matthäus, Kevin J. Painter, William Ho, Jon Riddell, Jeanette A. Johansson, Matthew J. Ford, Colin A. B. Jahoda, Vaclav Klika, Richard L. Mort, Denis J. Headon

PLoS Biol. 2017 Jul; 15(7): e2002117. Published online 2017 Jul 11. doi: 10.1371/journal.pbio.2002117

PMCID:: PMC5507405

Abstract Article PDF–24M

Select item 550595210.

Ectodysplasin target gene Fgf20 regulates mammary bud growth and ductal invasion and branching during puberty

Teresa Elo, Päivi H. Lindfors, Qiang Lan, Maria Voutilainen, Ewelina Trela, Claes Ohlsson, Sung-Ho Huh, David M. Ornitz, Matti Poutanen, Beatrice A. Howard, Marja L. Mikkola

Sci Rep. 2017; 7: 5049. Published online 2017 Jul 11. doi: 10.1038/s41598-017-04637-1

PMCID:: PMC5505952

Abstract Article PDF–6.1M

Select item 536223811.

SRC-2-mediated coactivation of anti-tumorigenic target genes suppresses MYC-induced liver cancer

Shruthy Suresh, Deniz Durakoglugil, Xiaorong Zhou, Bokai Zhu, Sarah A. Comerford, Chao Xing, Xian-Jin Xie, Brian York, Kathryn A. O’Donnell

PLoS Genet. 2017 Mar; 13(3): e1006650. Published online 2017 Mar 8. doi: 10.1371/journal.pgen.1006650

Correction in:: PLoS Genet. 2018 Apr; 14(4): e1007344.

PMCID:: PMC5362238

Abstract Article PDF–3.3M

Select item 529582112.

High-throughput discovery of novel developmental phenotypes

Mary E. Dickinson, Ann M. Flenniken, Xiao Ji, Lydia Teboul, Michael D. Wong, Jacqueline K. White, Terrence F. Meehan, Wolfgang J. Weninger, Henrik Westerberg, Hibret Adissu, Candice N. Baker, Lynette Bower, James M. Brown, L. Brianna Caddle, Francesco Chiani, Dave Clary, James Cleak, Mark J. Daly, James M. Denegre, Brendan Doe, Mary E. Dolan, Sarah M. Edie, Helmut Fuchs, Valerie Gailus-Durner, Antonella Galli, Alessia Gambadoro, Juan Gallegos, Shiying Guo, Neil R. Horner, Chih-wei Hsu, Sara J. Johnson, Sowmya Kalaga, Lance C. Keith, Louise Lanoue, Thomas N. Lawson, Monkol Lek, Manuel Mark, Susan Marschall, Jeremy Mason, Melissa L. McElwee, Susan Newbigging, Lauryl M.J. Nutter, Kevin A. Peterson, Ramiro Ramirez-Solis, Douglas J. Rowland, Edward Ryder, Kaitlin E. Samocha, John R. Seavitt, Mohammed Selloum, Zsombor Szoke-Kovacs, Masaru Tamura, Amanda G Trainor, Ilinca Tudose, Shigeharu Wakana, Jonathan Warren, Olivia Wendling, David B. West, Leeyean Wong, Atsushi Yoshiki, The International Mouse Phenotyping Consortium, Daniel G. MacArthur, Glauco P. Tocchini-Valentini, Xiang Gao, Paul Flicek, Allan Bradley, William C. Skarnes, Monica J. Justice, Helen E. Parkinson, Mark Moore, Sara Wells, Robert E. Braun, Karen L. Svenson, Martin Hrabe de Angelis, Yann Herault, Tim Mohun, Ann-Marie Mallon, R. Mark Henkelman, Steve D.M. Brown, David J. Adams, K.C. Kent Lloyd, Colin McKerlie, Arthur L. Beaudet, Maja Bucan, Stephen A. Murray

Nature. Author manuscript; available in PMC 2017 Mar 14.

Published in final edited form as: Nature. 2016 Sep 22; 537(7621): 508–514. Published online 2016 Sep 14. doi: 10.1038/nature19356

Correction in:: Nature. 2017 Nov 16; 551(7680): 398.

PMCID:: PMC5295821

Abstract Article PDF–3.0M

Select item 528738013.

Foxi3 deficiency compromises hair follicle stem cell specification and activation

Vera Shirokova, Leah C. Biggs, Maria Jussila, Takahiro Ohyama, Andrew K. Groves, Marja L. Mikkola

Stem Cells. Author manuscript; available in PMC 2017 Feb 1.

Published in final edited form as: Stem Cells. 2016 Jul; 34(7): 1896–1908. Published online 2016 Apr 4. doi: 10.1002/stem.2363

PMCID:: PMC5287380

Abstract Article PDF–3.4M

Select item 520103514.

Molecular dynamics of Dkk4 modulates Wnt action and regulates meibomian gland development

Jian Sima, Yulan Piao, Yaohui Chen, David Schlessinger

Development. 2016 Dec 15; 143(24): 4723–4735. doi: 10.1242/dev.143909

PMCID:: PMC5201035

Abstract Article

Select item 465133115.

Ectodysplasin/NF-κB Promotes Mammary Cell Fate via Wnt/β-catenin Pathway

Maria Voutilainen, Päivi H. Lindfors, Ewelina Trela, Darielle Lönnblad, Vera Shirokova, Teresa Elo, Elisa Rysti, Ruth Schmidt-Ullrich, Pascal Schneider, Marja L. Mikkola

PLoS Genet. 2015 Nov; 11(11): e1005676. Published online 2015 Nov 18. doi: 10.1371/journal.pgen.1005676

PMCID:: PMC4651331

Abstract Article PDF–51M

Select item 419757816.

Involvement of Wnt, Eda and Shh at defined stages of sweat gland development

Chang-Yi Cui, Mingzhu Yin, Jian Sima, Victoria Childress, Marc Michel, Yulan Piao, David Schlessinger

Development. 2014 Oct; 141(19): 3752–3760. doi: 10.1242/dev.109231

PMCID:: PMC4197578

Abstract Article

Select item 396495517.

The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data

Gautier Koscielny, Gagarine Yaikhom, Vivek Iyer, Terrence F. Meehan, Hugh Morgan, Julian Atienza-Herrero, Andrew Blake, Chao-Kung Chen, Richard Easty, Armida Di Fenza, Tanja Fiegel, Mark Grifiths, Alan Horne, Natasha A. Karp, Natalja Kurbatova, Jeremy C. Mason, Peter Matthews, Darren J. Oakley, Asfand Qazi, Jack Regnart, Ahmad Retha, Luis A. Santos, Duncan J. Sneddon, Jonathan Warren, Henrik Westerberg, Robert J. Wilson, David G. Melvin, Damian Smedley, Steve D. M. Brown, Paul Flicek, William C. Skarnes, Ann-Marie Mallon, Helen Parkinson

Nucleic Acids Res. 2014 Jan 1; 42(Database issue): D802–D809. Published online 2013 Nov 3. doi: 10.1093/nar/gkt977

PMCID:: PMC3964955

Abstract Article PDF–5.7M

Select item 391283318.

TGFβ regulates epithelial-mesenchymal interactions through WNT signaling activity to control muscle development in the soft palate

Jun-ichi Iwata, Akiko Suzuki, Toshiaki Yokota, Thach-Vu Ho, Richard Pelikan, Mark Urata, Pedro A. Sanchez-Lara, Yang Chai

Development. 2014 Feb 15; 141(4): 909–917. doi: 10.1242/dev.103093

PMCID:: PMC3912833

Abstract Article

Select item 375220419.

Conditionals by inversion provide a universal method for the generation of conditional alleles

Aris N. Economides, David Frendewey, Peter Yang, Melissa G. Dominguez, Anthony T. Dore, Ivan B. Lobov, Trikaldarshi Persaud, Jose Rojas, Joyce McClain, Peter Lengyel, Gustavo Droguett, Rostislav Chernomorsky, Sean Stevens, Wojtek Auerbach, Thomas M. DeChiara, William Pouyemirou, Joseph M. Cruz, Jr., Kieran Feeley, Ian A. Mellis, Jason Yasenchack, Sarah J. Hatsell, LiQin Xie, Esther Latres, Lily Huang, Yuhong Zhang, Evangelos Pefanis, Dimitris Skokos, Ron A. Deckelbaum, Susan D. Croll, Samuel Davis, David M. Valenzuela, Nicholas W. Gale, Andrew J. Murphy, George D. Yancopoulos

Proc Natl Acad Sci U S A. 2013 Aug 20; 110(34): E3179–E3188. Published online 2013 Aug 5. doi: 10.1073/pnas.1217812110

PMCID:: PMC3752204

Abstract Article PDF–1.8M

Select item 359463520.

Epidermal Wnt controls hair follicle induction by orchestrating dynamic signaling crosstalk between the epidermis and dermis

Jiang Fu, Wei Hsu

J Invest Dermatol. Author manuscript; available in PMC 2013 Oct 1.

Published in final edited form as: J Invest Dermatol. 2013 Apr; 133(4): 890–898. Published online 2012 Nov 29. doi: 10.1038/jid.2012.407

PMCID:: PMC3594635

Abstract Article PDF–2.0M

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