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Select item 108911541.

Modulation of cAMP/cGMP signaling as prevention of congenital heart defects in Pde2A deficient embryos: a matter of oxidative stress

Silvia Cardarelli, Martina Biglietto, Tiziana Orsini, Valentina Fustaino, Lucia Monaco, Ana Gabriela de Oliveira do Rêgo, Francesca Liccardo, Silvia Masciarelli, Francesco Fazi, Fabio Naro, Luciana De Angelis, Manuela Pellegrini

Cell Death Dis. 2024 Feb; 15(2): 169. Published online 2024 Feb 23. doi: 10.1038/s41419-024-06549-1

PMCID:: PMC10891154

Abstract Article PDF–2.6M

Select item 108131462.

Uncoupling Protein 3 Catalyzes the Exchange of C4 Metabolites Similar to UCP2

Jürgen Kreiter, Tatyana Tyschuk, Elena E. Pohl

Biomolecules. 2024 Jan; 14(1): 21. Published online 2023 Dec 22. doi: 10.3390/biom14010021

PMCID:: PMC10813146

Abstract Article PDF–2.4M

Select item 105071623.

Mitochondrial network adaptations of microglia reveal sex-specific stress response after injury and UCP2 knockout

Margaret E. Maes, Gloria Colombo, Florianne E. Schoot Uiterkamp, Felix Sternberg, Alessandro Venturino, Elena E. Pohl, Sandra Siegert

iScience. 2023 Oct 20; 26(10): 107780. Published online 2023 Aug 29. doi: 10.1016/j.isci.2023.107780

PMCID:: PMC10507162

Abstract Article PDF–7.8M

Select item 98857594.

UCP2-dependent redox sensing in POMC neurons regulates feeding

Nal Ae Yoon, Sungho Jin, Jung Dae Kim, Zhong Wu Liu, Qiushi Sun, Rebecca Cardone, Richard Kibbey, Sabrina Diano

Cell Rep. Author manuscript; available in PMC 2023 Jan 30.

Published in final edited form as: Cell Rep. 2022 Dec 27; 41(13): 111894. doi: 10.1016/j.celrep.2022.111894

PMCID:: PMC9885759

Abstract Article PDF–2.7M

Select item 96232375.

UCP2 KO mice exhibit ameliorated obesity and inflammation induced by high-fat diet feeding

Do Hyun Kim, Hye Jin Kim, Je Kyung Seong

BMB Rep. 2022 Oct 31; 55(10): 500–505. Published online 2022 Oct 31. doi: 10.5483/BMBRep.2022.55.10.056

PMCID:: PMC9623237

Abstract Article PDF–21M

Select item 95834876.

AAV-ie-mediated UCP2 overexpression accelerates inner hair cell loss during aging in vivo

Chunli Zhao, Zijing Yang, Zhongrui Chen, Wenqi Liang, Shusheng Gong, Zhengde Du

Mol Med. 2022; 28: 124. Published online 2022 Oct 20. doi: 10.1186/s10020-022-00552-y

PMCID:: PMC9583487

Abstract Article PDF–2.2M

Select item 95007417.

Activating PPARβ/δ Protects against Endoplasmic Reticulum Stress-Induced Astrocytic Apoptosis via UCP2-Dependent Mitophagy in Depressive Model

Juan Ji, Shangze Li, Zikai Jiang, Jianbing Yu, Yuqin Sun, Zhenyu Cai, Yinfeng Dong, Xiulan Sun

Int J Mol Sci. 2022 Sep; 23(18): 10822. Published online 2022 Sep 16. doi: 10.3390/ijms231810822

PMCID:: PMC9500741

Abstract Article PDF–44M

Select item 94625008.

UCP2 modulates cardiomyocyte cell cycle activity, acetyl-CoA, and histone acetylation in response to moderate hypoxia

Vagner O.C. Rigaud, Clare Zarka, Justin Kurian, Daria Harlamova, Andrea Elia, Nicole Kasatkin, Jaslyn Johnson, Michael Behanan, Lindsay Kraus, Hannah Pepper, Nathaniel W. Snyder, Sadia Mohsin, Steven R. Houser, Mohsin Khan

JCI Insight. 2022 Aug 8; 7(15): e155475. Published online 2022 Aug 8. doi: 10.1172/jci.insight.155475

PMCID:: PMC9462500

Abstract Article PDF–10M

Select item 93902369.

Endothelial UCP2 Is a Mechanosensitive Suppressor of Atherosclerosis

Jiang-Yun Luo, Chak Kwong Cheng, Lei He, Yujie Pu, Yang Zhang, Xiao Lin, Aimin Xu, Chi Wai Lau, Xiao Yu Tian, Ronald Ching Wan Ma, Hanjoong Jo, Yu Huang

Circ Res. 2022 Aug 19; 131(5): 424–441. Published online 2022 Jul 28. doi: 10.1161/CIRCRESAHA.122.321187

PMCID:: PMC9390236

Abstract Article PDF–9.4M

Select item 924978810.

DDX1 vesicles control calcium-dependent mitochondrial activity in mouse embryos

Yixiong Wang, Lubna Yasmin, Lei Li, Pinzhang Gao, Xia Xu, Xuejun Sun, Roseline Godbout

Nat Commun. 2022; 13: 3794. Published online 2022 Jul 1. doi: 10.1038/s41467-022-31497-9

PMCID:: PMC9249788

Abstract Article PDF–8.3M

Select item 921865611.

Endothelial Cells Mediated by UCP2 Control the Neurogenic‐to‐Astrogenic Neural Stem Cells Fate Switch During Brain Development

Wenwen Wang, Libo Su, Yanyan Wang, Chenxiao Li, Fen Ji, Jianwei Jiao

Adv Sci (Weinh) 2022 Jun; 9(18): 2105208. Published online 2022 Apr 30. doi: 10.1002/advs.202105208

PMCID:: PMC9218656

Abstract Article PDF–8.7M

Select item 903218112.

Microglial FABP4-UCP2 Axis Modulates Neuroinflammation and Cognitive Decline in Obese Mice

Simon W. So, Kendra M. Fleming, Cayla M. Duffy, Joshua P. Nixon, David A. Bernlohr, Tammy A. Butterick

Int J Mol Sci. 2022 Apr; 23(8): 4354. Published online 2022 Apr 14. doi: 10.3390/ijms23084354

PMCID:: PMC9032181

Abstract Article PDF–3.3M

Select item 896144913.

Astrocytic insulin signaling couples brain glucose uptake with nutrient availability

Cristina Garcia-Caceres, Carmelo Quarta, Luis Varela, Yuanqing Gao, Tim Gruber, Beata Legutko, Martin Jastroch, Pia Johansson, Jovica Ninkovic, Chun-Xia Yi, Ophelia Le Thuc, Klara Szigeti-Buck, Weikang Cai, Carola W. Meyer, Paul T. Pfluger, Ana M. Fernandez, Serge Luquet, Stephen C. Woods, Ignacio Torres-Alemán, C. Ronald Kahn, Magdalena Götz, Tamas L. Horvath, Matthias H. Tschöp

Cell. Author manuscript; available in PMC 2022 Mar 29.

Published in final edited form as: Cell. 2016 Aug 11; 166(4): 867–880. doi: 10.1016/j.cell.2016.07.028

PMCID:: PMC8961449

Abstract Article PDF–2.6M

Select item 893724514.

Thioredoxin Prevents Loss of UCP2 in Hyperoxia via MKK4–p38 MAPK–PGC1α Signaling and Limits Oxygen Toxicity

Somasundaram Raghavan, Venkatesh Kundumani-Sridharan, Sudhir Kumar, Carl W. White, Kumuda C. Das

Am J Respir Cell Mol Biol. 2022 Mar; 66(3): 323–336. Published online 2021 Dec 10. doi: 10.1165/rcmb.2021-0219OC

PMCID:: PMC8937245

Abstract Article PDF–2.2M

Select item 854185915.

Irisin Rescues Blood-Brain Barrier Permeability following Traumatic Brain Injury and Contributes to the Neuroprotection of Exercise in Traumatic Brain Injury

Peipei Guo, Zhao Jin, Jin Wang, Aming Sang, Huisheng Wu

Oxid Med Cell Longev. 2021; 2021: 1118981. Published online 2021 Oct 16. doi: 10.1155/2021/1118981

PMCID:: PMC8541859

Abstract Article PDF–3.4M

Select item 832206716.

Exercise training mitigates ER stress and UCP2 deficiency-associated coronary vascular dysfunction in atherosclerosis

Junyoung Hong, Eunkyung Park, Jonghae Lee, Yang Lee, Bridgette V. Rooney, Yoonjung Park

Sci Rep. 2021; 11: 15449. Published online 2021 Jul 29. doi: 10.1038/s41598-021-94944-5

PMCID:: PMC8322067

Abstract Article PDF–5.1M

Select item 805679517.

Ucp2-dependent microglia-neuronal coupling controls ventral hippocampal circuit function and anxiety-like behavior

Yuki Yasumoto, Milan Stoiljkovic, Jung Dae Kim, Matija Sestan-Pesa, Xiao-Bing Gao, Sabrina Diano, Tamas L. Horvath

Mol Psychiatry. 2021; 26(7): 2740–2752. Published online 2021 Apr 20. doi: 10.1038/s41380-021-01105-1

PMCID:: PMC8056795

Abstract Article PDF–2.7M

Select item 778080618.

Uncoupling protein 2‐mediated metabolic adaptations define cardiac cell function in the heart during transition from young to old age

Justin Kurian, Antonia E. Yuko, Nicole Kasatkin, Vagner O. C. Rigaud, Kelsey Busch, Daria Harlamova, Marcus Wagner, Fabio A. Recchia, Hong Wang, Sadia Mohsin, Steven R. Houser, Mohsin Khan

Stem Cells Transl Med. 2021 Jan; 10(1): 144–156. Published online 2020 Sep 10. doi: 10.1002/sctm.20-0123

PMCID:: PMC7780806

Abstract Article PDF–5.6M

Select item 776295319.

The role of uncoupling protein 2 in macrophages and its impact on obesity-induced adipose tissue inflammation and insulin resistance

Xanthe A. M. H. van Dierendonck, Tiphaine Sancerni, Marie-Clotilde Alves-Guerra, Rinke Stienstra

J Biol Chem. 2020 Dec 18; 295(51): 17535–17548. Published online 2020 Oct 13. doi: 10.1074/jbc.RA120.014868

PMCID:: PMC7762953

Abstract Article PDF–3.5M

Select item 764534520.

Deletion of mitochondrial uncoupling protein 2 exacerbates mitophagy and cell apoptosis after cerebral ischemia and reperfusion injury in mice

Maotao He, Ting Zhang, Yucheng Fan, Yanmei Ma, Jianzhong Zhang, Li Jing, P. Andy Li

Int J Med Sci. 2020; 17(17): 2869–2878. Published online 2020 Oct 16. doi: 10.7150/ijms.49849

PMCID:: PMC7645345

Abstract Article PDF–1.6M

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