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Items: 1 to 20 of 35

1.
OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization
Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti
Science. Author manuscript; available in PMC 2022 Sep 11.
Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983
PMCID:
PMC9119736
ArticlePDF–3.3M
2.
MEKK1-Dependent Activation of the CRL4 Complex Is Important for DNA Damage-Induced Degradation of p21 and DDB2 and Cell Survival
Susanne Bacher, Hilda Stekman, Carla M. Farah, Annika Karger, Michael Kracht, M. Lienhard Schmitz
Mol Cell Biol. 2021 Oct; 41(10): e00081-21. Prepublished online 2021 Jul 12. Published online 2021 Sep 24. doi: 10.1128/MCB.00081-21
PMCID:
PMC8462458
ArticlePDF–3.1M
3.
Contribution of a European‐Prevalent Variant near CD83 and an East Asian–Prevalent Variant near IL17RB to Herpes Zoster Risk in Tofacitinib Treatment: Results of Genome‐Wide Association Study Meta‐Analyses
Nan Bing, Huanyu Zhou, Xing Chen, Tomohiro Hirose, Yuta Kochi, Yumi Tsuchida, Kazuyoshi Ishigaki, Shuji Sumitomo, Keishi Fujio, Baohong Zhang, Hernan Valdez, Michael S. Vincent, David Martin, James D. Clark
Arthritis Rheumatol. 2021 Jul; 73(7): 1155–1166. Published online 2021 May 28. doi: 10.1002/art.41655
PMCID:
PMC8361995
ArticlePDF–782K
4.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
ArticlePDF–2.2M
5.
CRL4-DCAF12 Ubiquitin Ligase Controls MOV10 RNA Helicase during Spermatogenesis and T Cell Activation
Tomas Lidak, Nikol Baloghova, Vladimir Korinek, Radislav Sedlacek, Jana Balounova, Petr Kasparek, Lukas Cermak
Int J Mol Sci. 2021 May; 22(10): 5394. Published online 2021 May 20. doi: 10.3390/ijms22105394
PMCID:
PMC8161014
ArticlePDF–7.9M
6.
IL-17B/IL-17RB signaling cascade contributes to self-renewal and tumorigenesis of cancer stem cells by regulating Beclin-1 ubiquitination
Qingli Bie, Hui Song, Xinke Chen, Xiao Yang, Shuo Shi, Lihua Zhang, Rou Zhao, Li Wei, Baogui Zhang, Huabao Xiong, Bin Zhang
Oncogene. 2021; 40(12): 2200–2216. Published online 2021 Mar 1. doi: 10.1038/s41388-021-01699-4
PMCID:
PMC7994204
ArticlePDF–6.6M
7.
An IMiD-induced SALL4 degron system for selective degradation of target proteins
Satoshi Yamanaka, Yuki Shoya, Saya Matsuoka, Hisayo Nishida-Fukuda, Norio Shibata, Tatsuya Sawasaki
Commun Biol. 2020; 3: 515. Published online 2020 Sep 18. doi: 10.1038/s42003-020-01240-5
PMCID:
PMC7501283
ArticlePDF–3.3M
8.
Lineage tracing and targeting of IL17RB+ tuft cell-like human colorectal cancer stem cells
Norihiro Goto, Akihisa Fukuda, Yuichi Yamaga, Takaaki Yoshikawa, Takahisa Maruno, Hisatsugu Maekawa, Susumu Inamoto, Kenji Kawada, Yoshiharu Sakai, Hiroyuki Miyoshi, Makoto Mark Taketo, Tsutomu Chiba, Hiroshi Seno
Proc Natl Acad Sci U S A. 2019 Jun 25; 116(26): 12996–13005. Published online 2019 Jun 10. doi: 10.1073/pnas.1900251116
PMCID:
PMC6601016
ArticlePDF–2.8M
9.
IL-4 Induces IL17Rb Gene Transcription in Monocytic Cells with Coordinate Autocrine IL-25 Signaling
Nathaniel M. Weathington, Shreya M. Kanth, Qiaoke Gong, James Londino, Akihiko Hoji, Mauricio Rojas, John Trudeau, Sally Wenzel, Rama K. Mallampalli
Am J Respir Cell Mol Biol. 2017 Sep; 57(3): 346–354. doi: 10.1165/rcmb.2016-0316OC
PMCID:
PMC5625225
ArticlePDF–1.2M
10.
Architecture of the human interactome defines protein communities and disease networks
Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper
Nature. Author manuscript; available in PMC 2017 Nov 17.
Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366
PMCID:
PMC5531611
ArticlePDF–2.7M
11.
The antiobesity factor WDTC1 suppresses adipogenesis via the CRL4WDTC1 E3 ligase
Beezly S Groh, Feng Yan, Matthew D Smith, Yanbao Yu, Xian Chen, Yue Xiong
EMBO Rep. 2016 May; 17(5): 638–647. Published online 2016 Apr 9. doi: 10.15252/embr.201540500
PMCID:
PMC5341520
ArticlePDF–1.1M
12.
IL-17RB+ granulocytes are associated with airflow obstruction in asthma
Lin Li, Nicholas W. Lukacs, Matthew A. Schaller, Bryan Petersen, Alan P. Baptist
Ann Allergy Asthma Immunol. Author manuscript; available in PMC 2017 Dec 1.
Published in final edited form as: Ann Allergy Asthma Immunol. 2016 Dec; 117(6): 674–679. doi: 10.1016/j.anai.2016.09.448
PMCID:
PMC5172383
ArticlePDF–604K
13.
PCNA-Dependent Cleavage and Degradation of SDE2 Regulates Response to Replication Stress
Ukhyun Jo, Winson Cai, Jingming Wang, Yoojin Kwon, Alan D. D’Andrea, Hyungjin Kim
PLoS Genet. 2016 Dec; 12(12): e1006465. Published online 2016 Dec 1. doi: 10.1371/journal.pgen.1006465
PMCID:
PMC5131917
ArticlePDF–3.0M
14.
Glutamine triggers acetylation-dependent degradation of glutamine synthetase via the thalidomide receptor cereblon
Thang Van Nguyen, J. Eugene Lee, Michael J. Sweredoski, Seung-Joo Yang, Seung-Je Jeon, Joseph S. Harrison, Jung-Hyuk Yim, Sang Ghil Lee, Hiroshi Handa, Brian Kuhlman, Ji-Seon Jeong, Justin M. Reitsma, Chul-Seung Park, Sonja Hess, Raymond J. Deshaies
Mol Cell. Author manuscript; available in PMC 2017 Mar 17.
Published in final edited form as: Mol Cell. 2016 Mar 17; 61(6): 809–820. doi: 10.1016/j.molcel.2016.02.032
PMCID:
PMC4889030
ArticlePDF–2.3M
15.
Non-tumor tissue derived interleukin-17B activates IL-17RB/AKT/β-catenin pathway to enhance the stemness of gastric cancer
Qingli Bie, Caixia Sun, Aihua Gong, Chunye Li, Zhaoliang Su, Dong Zheng, Xiaoyun Ji, Yumin Wu, Qi Guo, Shengjun Wang, Huaxi Xu
Sci Rep. 2016; 6: 25447. Published online 2016 May 5. doi: 10.1038/srep25447
PMCID:
PMC4857095
ArticlePDF–2.3M
16.
Assessment of the prognostic and predictive utility of the Breast Cancer Index (BCI): an NCIC CTG MA.14 study
Dennis C. Sgroi, Judy-Anne W. Chapman, T. Badovinac-Crnjevic, Elizabeth Zarella, Shemeica Binns, Yi Zhang, Catherine A. Schnabel, Mark G. Erlander, Kathleen I. Pritchard, Lei Han, Lois E. Shepherd, Paul E. Goss, Michael Pollak
Breast Cancer Res. 2016; 18: 1. Published online 2016 Jan 4. doi: 10.1186/s13058-015-0660-6
PMCID:
PMC4700696
ArticlePDF–670K
17.
Targeting interleukin-17 receptors
Wen-Hwa Lee, Heng-Hsiung Wu, Chun-Kai Huang
Oncotarget. 2015 Jul 30; 6(21): 18244–18245. Published online 2015 Jul 17. doi: 10.18632/oncotarget.4892
PMCID:
PMC4621885
ArticlePDF–885K
18.
Targeting IL-17B–IL-17RB signaling with an anti–IL-17RB antibody blocks pancreatic cancer metastasis by silencing multiple chemokines
Heng-Hsiung Wu, Wendy W. Hwang-Verslues, Wen-Hsin Lee, Chun-Kai Huang, Pei-Chi Wei, Chia-Lin Chen, Jin-Yuh Shew, Eva Y.-H.P. Lee, Yung-Ming Jeng, Yu-Wen Tien, Che Ma, Wen-Hwa Lee
J Exp Med. 2015 Mar 9; 212(3): 333–349. doi: 10.1084/jem.20141702
PMCID:
PMC4354366
ArticlePDF–4.7M
19.
A biallelic ACT1 mutation selectively abolishes interleukin-17 responses in humans with chronic mucocutaneous candidiasis
Bertrand Boisson, Chenhui Wang, Vincent Pedergnana, Ling Wu, Sophie Cypowyj, Michel Rybojad, Aziz Belkadi, Capucine Picard, Laurent Abel, Claire Fieschi, Anne Puel, Xiaoxia Li, Jean-Laurent Casanova
Immunity. Author manuscript; available in PMC 2014 Oct 17.
Published in final edited form as: Immunity. 2013 Oct 17; 39(4): 10.1016/j.immuni.2013.09.002. Published online 2013 Oct 10. doi: 10.1016/j.immuni.2013.09.002
PMCID:
PMC3873857
ArticlePDF–2.0M
20.
Nine Loci for Ocular Axial Length Identified through Genome-wide Association Studies, Including Shared Loci with Refractive Error
Ching-Yu Cheng, Maria Schache, M. Kamran Ikram, Terri L. Young, Jeremy A. Guggenheim, Veronique Vitart, Stuart MacGregor, Virginie J.M. Verhoeven, Veluchamy A. Barathi, Jiemin Liao, Pirro G. Hysi, Joan E. Bailey-Wilson, Beate St. Pourcain, John P. Kemp, George McMahon, Nicholas J. Timpson, David M. Evans, Grant W. Montgomery, Aniket Mishra, Ya Xing Wang, Jie Jin Wang, Elena Rochtchina, Ozren Polasek, Alan F. Wright, Najaf Amin, Elisabeth M. van Leeuwen, James F. Wilson, Craig E. Pennell, Cornelia M. van Duijn, Paulus T.V.M. de Jong, Johannes R. Vingerling, Xin Zhou, Peng Chen, Ruoying Li, Wan-Ting Tay, Yingfeng Zheng, Merwyn Chew, Consortium for Refractive Error and Myopia, Kathryn P. Burdon, Jamie E. Craig, Sudha K. Iyengar, Robert P. Igo, Jr., Jonathan H. Lass, Jr., The Fuchs’ Genetics Multi-Center Study Group, Emily Y. Chew, Toomas Haller, Evelin Mihailov, Andres Metspalu, Juho Wedenoja, Claire L. Simpson, Robert Wojciechowski, René Höhn, Alireza Mirshahi, Tanja Zeller, Norbert Pfeiffer, Karl J. Lackner, Wellcome Trust Case Control Consortium 2, Thomas Bettecken, Thomas Meitinger, Konrad Oexle, Mario Pirastu, Laura Portas, Abhishek Nag, Katie M. Williams, Ekaterina Yonova-Doing, Ronald Klein, Barbara E. Klein, S. Mohsen Hosseini, Andrew D. Paterson, The Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions, and Complications Research Group, Kari-Matti Makela, Terho Lehtimaki, Mika Kahonen, Olli Raitakari, Nagahisa Yoshimura, Fumihiko Matsuda, Li Jia Chen, Chi Pui Pang, Shea Ping Yip, Maurice K.H. Yap, Akira Meguro, Nobuhisa Mizuki, Hidetoshi Inoko, Paul J. Foster, Jing Hua Zhao, Eranga Vithana, E-Shyong Tai, Qiao Fan, Liang Xu, Harry Campbell, Brian Fleck, Igor Rudan, Tin Aung, Albert Hofman, André G. Uitterlinden, Goran Bencic, Chiea-Chuen Khor, Hannah Forward, Olavi Pärssinen, Paul Mitchell, Fernando Rivadeneira, Alex W. Hewitt, Cathy Williams, Ben A. Oostra, Yik-Ying Teo, Christopher J. Hammond, Dwight Stambolian, David A. Mackey, Caroline C.W. Klaver, Tien-Yin Wong, Seang-Mei Saw, Paul N. Baird
Am J Hum Genet. 2013 Aug 8; 93(2): 264–277. doi: 10.1016/j.ajhg.2013.06.016
PMCID:
PMC3772747
ArticlePDF–959K

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