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Items: 1 to 20 of 139

1.
TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing
Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan
Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233
PMCID:
PMC10237422
AbstractArticlePDF–23M
2.
CLEC16A interacts with retromer and TRIM27, and its loss impairs endosomal trafficking and neurodevelopment
Daphne J. Smits, Jordy Dekker, Rachel Schot, Brahim Tabarki, Amal Alhashem, Jeroen A. A. Demmers, Dick H. W. Dekkers, Antonio Romito, Peter J. van der Spek, Tjakko J. van Ham, Aida M. Bertoli-Avella, Grazia M. S. Mancini
Hum Genet. 2023; 142(3): 379–397. Published online 2022 Dec 20. doi: 10.1007/s00439-022-02511-3
PMCID:
PMC9950183
AbstractArticlePDF–2.4M
3.
The variants in PTPRB, TRAF3IP3, and DISC1 genes were associated with Graves’ disease in the Chinese population
Wei Li, Haidong Jiang, Xu Chen, Kevin Yang, Xindan Deng, Zheng Tang, Zhihui Hu, Xiaodan Zhang, Shihan Lin, Yuanlin Zou, Hui Wu
Medicine (Baltimore) 2022 Nov 11; 101(45): e31501. Published online 2022 Nov 11. doi: 10.1097/MD.0000000000031501
PMCID:
PMC9666212
AbstractArticlePDF–527K
4.
Regulation of sensorimotor gating via Disc1/Huntingtin-mediated Bdnf transport in the cortico-striatal circuit
Hanna Jaaro-Peled, Sunil Kumar, Dalton Hughes, Akiko Sumitomo, Sun-Hong Kim, Sandra Zoubovsky, Yuki Hirota-Tsuyada, Diana Zala, Julie Bruyere, Brittany M. Katz, Beverly Huang, Rafael Flores, III, Soumya Narayan, Zhipeng Hou, Aris N. Economides, Takatoshi Hikida, William C. Wetsel, Karl Deisseroth, Susumu Mori, Nicholas J. Brandon, Motomasa Tanaka, Koko Ishizuka, Miles D. Houslay, Frédéric Saudou, Kafui Dzirasa, Akira Sawa, Toshifumi Tomoda
Mol Psychiatry. Author manuscript; available in PMC 2022 Aug 14.
Published in final edited form as: Mol Psychiatry. 2022 Mar; 27(3): 1805–1815. Published online 2022 Feb 14. doi: 10.1038/s41380-021-01389-3
PMCID:
PMC9272458
AbstractArticlePDF–1.8M
5.
Combining fMRI and DISC1 gene haplotypes to understand working memory-related brain activity in schizophrenia
Maria Guardiola-Ripoll, Alejandro Sotero-Moreno, Carmen Almodóvar-Payá, Noemí Hostalet, Amalia Guerrero-Pedraza, Núria Ramiro, Jordi Ortiz-Gil, Bárbara Arias, Mercè Madre, Joan Soler-Vidal, Raymond Salvador, Peter J. McKenna, Edith Pomarol-Clotet, Mar Fatjó-Vilas
Sci Rep. 2022; 12: 7351. Published online 2022 May 5. doi: 10.1038/s41598-022-10660-8
PMCID:
PMC9072540
AbstractArticlePDF–1.5M
6.
The involvement of Parkin-dependent mitophagy in the anti-cancer activity of Ginsenoside
Xin Sun, Yeting Hong, Yuhan Shu, Caixia Wu, Guiqin Ye, Hanxiao Chen, Hongying Zhou, Ruilan Gao, Jianbin Zhang
J Ginseng Res. 2022 Mar; 46(2): 266–274. Published online 2021 Jul 8. doi: 10.1016/j.jgr.2021.06.009
PMCID:
PMC9058836
AbstractArticlePDF–2.9M
7.
The D2R-DISC1 protein complex and associated proteins are altered in schizophrenia and normalized with antipsychotic treatment
Jijun Wang, Ping Su, Jian Yang, Lihua Xu, Aihua Yuan, Chunbo Li, Tianhong Zhang, Fang Dong, Jingjing Zhou, James Samsom, Albert H.C. Wong, Fang Liu
J Psychiatry Neurosci. 2022 Mar-Apr; 47(2): E134–E147. Published online 2022 Mar 31. doi: 10.1503/jpn.210145
PMCID:
PMC8979657
AbstractArticlePDF–2.9M
8.
Proteome‐scale mapping of binding sites in the unstructured regions of the human proteome
Caroline Benz, Muhammad Ali, Izabella Krystkowiak, Leandro Simonetti, Ahmed Sayadi, Filip Mihalic, Johanna Kliche, Eva Andersson, Per Jemth, Norman E Davey, Ylva Ivarsson
Mol Syst Biol. 2022 Jan; 18(1): e10584. Published online 2022 Jan 19. doi: 10.15252/msb.202110584
PMCID:
PMC8769072
AbstractArticlePDF–2.9M
9.
Effects of DISC1 on Alzheimer’s disease cell models assessed by iTRAQ proteomics analysis
Jiajie Lu, Rihong Huang, Yuecheng Peng, Haojian Wang, Zejia Feng, Yongyang Fan, Zhaorong Zeng, Yezhong Wang, Jiana Wei, Zhaotao Wang
Biosci Rep. 2022 Jan 28; 42(1): BSR20211150. Published online 2022 Jan 11. doi: 10.1042/BSR20211150
PMCID:
PMC8753346
AbstractArticlePDF–1.4M
10.
Arginine methylation and ubiquitylation crosstalk controls DNA end-resection and homologous recombination repair
Maria Pilar Sanchez-Bailon, Soo-Youn Choi, Elizabeth R. Dufficy, Karan Sharma, Gavin S. McNee, Emma Gunnell, Kelly Chiang, Debashish Sahay, Sarah Maslen, Grant S. Stewart, J. Mark Skehel, Ingrid Dreveny, Clare C. Davies
Nat Commun. 2021; 12: 6313. Published online 2021 Nov 2. doi: 10.1038/s41467-021-26413-6
PMCID:
PMC8564520
AbstractArticlePDF–2.3M
11.
BioID reveals an ATG9A interaction with ATG13‐ATG101 in the degradation of p62/SQSTM1‐ubiquitin clusters
Ashari R Kannangara, Daniel M Poole, Colten M McEwan, Joshua C Youngs, Vajira K Weerasekara, Alex M Thornock, Misael T Lazaro, Eranga R Balasooriya, Laura M Oh, Erik J Soderblom, Jonathan J Lee, Daniel L Simmons, Joshua L Andersen
EMBO Rep. 2021 Oct 5; 22(10): e51136. Published online 2021 Aug 9. doi: 10.15252/embr.202051136
PMCID:
PMC8490997
AbstractArticlePDF–4.5M
12.
Structural interaction between DISC1 and ATF4 underlying transcriptional and synaptic dysregulation in an iPSC model of mental disorders
Xinyuan Wang, Fei Ye, Zhexing Wen, Ziyuan Guo, Chuan Yu, Wei-Kai Huang, Francisca Rojas Ringeling, Yijing Su, Wei Zheng, Guomin Zhou, Kimberly M. Christian, Hongjun Song, Mingjie Zhang, Guo-li Ming
Mol Psychiatry. Author manuscript; available in PMC 2021 Sep 16.
Published in final edited form as: Mol Psychiatry. 2021 Apr; 26(4): 1346–1360. Published online 2019 Aug 23. doi: 10.1038/s41380-019-0485-2
PMCID:
PMC8444148
AbstractArticlePDF–1.8M
13.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
14.
Altered expression of the DISC1 gene in peripheral blood of patients with schizophrenia
Xiaoqian Fu, Guofu Zhang, Yansong Liu, Ling Zhang, Fuquan Zhang, Conghua Zhou
BMC Med Genet. 2020; 21: 194. Published online 2020 Oct 2. doi: 10.1186/s12881-020-01132-9
PMCID:
PMC7532617
AbstractArticlePDF–588K
15.
Kinase Interaction Network Expands Functional and Disease Roles of Human Kinases
Marija Buljan, Rodolfo Ciuffa, Audrey van Drogen, Anton Vichalkovski, Martin Mehnert, George Rosenberger, Sohyon Lee, Markku Varjosalo, Lucia Espona Pernas, Vincent Spegg, Berend Snijder, Ruedi Aebersold, Matthias Gstaiger
Mol Cell. 2020 Aug 6; 79(3): 504–520.e9. doi: 10.1016/j.molcel.2020.07.001
PMCID:
PMC7427327
AbstractArticle
16.
The DISC1–Girdin complex – a missing link in signaling to the T cell cytoskeleton
Nicholas Maskalenko, Shubhankar Nath, Adarsh Ramakrishnan, Nadia Anikeeva, Yuri Sykulev, Martin Poenie
J Cell Sci. 2020 Jul 1; 133(13): jcs242875. Published online 2020 Jul 6. doi: 10.1242/jcs.242875
PMCID:
PMC7358132
AbstractArticle
17.
The DISC1 R264Q variant increases affinity for the dopamine D2 receptor and increases GSK3 activity
Ping Su, Hailong Zhang, Albert H. C. Wong, Fang Liu
Mol Brain. 2020; 13: 87. Published online 2020 Jun 3. doi: 10.1186/s13041-020-00625-1
PMCID:
PMC7271519
AbstractArticlePDF–1.3M
18.
A reference map of the human binary protein interactome
Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood
Nature. Author manuscript; available in PMC 2020 Oct 8.
Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x
PMCID:
PMC7169983
AbstractArticlePDF–5.4M
19.
Disrupted-in-Schizophrenia 1 (DISC1) functional polymorphisms and D2/D3 receptor availability: a [11C]-(+)-PHNO imaging study
Tarik Dahoun, Matthew M Nour, Rick A Adams, Svenja Trossbach, Sang hyuck Lee, Hamel Patel, Charles Curtis, Carsten Korth, Oliver D. Howes
Genes Brain Behav. Author manuscript; available in PMC 2020 Mar 30.
Published in final edited form as: Genes Brain Behav. 2019 Nov 1; 18(8): e12596. Published online 2019 Jul 5. doi: 10.1111/gbb.12596
PMCID:
PMC7105392
AbstractArticlePDF–1.2M
20.
A Brain‐wide association study of DISC1 genetic variants reveals a relationship with the structure and functional connectivity of the precuneus in schizophrenia
Xiaohong Gong, Wenlian Lu, Keith M. Kendrick, Weidan Pu, Chu Wang, Li Jin, Guangmin Lu, Zhening Liu, Haihong Liu, Jianfeng Feng
Hum Brain Mapp. 2014 Nov; 35(11): 5414–5430. Published online 2014 Jun 7. doi: 10.1002/hbm.22560
PMCID:
PMC6869119
AbstractArticlePDF–801K

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