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Items: 1 to 20 of 30

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
Acyloxyacyl hydrolase promotes pulmonary defense by preventing alveolar macrophage tolerance
Xiaofang Cheng, Wei Jiang, Yeying Chen, Benkun Zou, Zhiyan Wang, Lu Gan, Zeling Xiao, Changshun Li, Cheng-Yun Yu, Yimeng Lu, Zeyao Han, Jiashun Zeng, Jie Gu, Tianqing Chu, Mingsheng Fu, Yiwei Chu, Wenhong Zhang, Jianguo Tang, Mingfang Lu
PLoS Pathog. 2023 Jul; 19(7): e1011556. Published online 2023 Jul 27. doi: 10.1371/journal.ppat.1011556
PMCID:
PMC10409266
AbstractArticlePDF–3.8M
3.
Acyloxyacyl hydrolase is a host determinant of gut microbiome-mediated pelvic pain
Afrida Rahman-Enyart, Wenbin Yang, Ryan E. Yaggie, Bryan A. White, Michael Welge, Loretta Auvil, Matthew Berry, Colleen Bushell, John M. Rosen, Charles N. Rudick, Anthony J. Schaeffer, David J. Klumpp
Am J Physiol Regul Integr Comp Physiol. 2021 Sep 1; 321(3): R396–R412. Published online 2021 Jul 28. doi: 10.1152/ajpregu.00106.2021
PMCID:
PMC8530758
AbstractArticle
4.
Comprehensive Proteomic Profiling of Urinary Exosomes and Identification of Potential Non-invasive Early Biomarkers of Alzheimer’s Disease in 5XFAD Mouse Model
Zhiqi Song, Yanfeng Xu, Ling Zhang, Li Zhou, Yu Zhang, Yunlin Han, Xianglei Li, Pin Yu, Yajin Qu, Wenjie Zhao, Chuan Qin
Front Genet. 2020; 11: 565479. Published online 2020 Nov 5. doi: 10.3389/fgene.2020.565479
PMCID:
PMC7674956
AbstractArticlePDF–11M
5.
AOAH remodels arachidonic acid-containing phospholipid pools in a model of interstitial cystitis pain: A MAPP Network study
Wenbin Yang, Ryan E. Yaggie, Anthony J. Schaeffer, David J. Klumpp
PLoS One. 2020; 15(9): e0235384. Published online 2020 Sep 14. doi: 10.1371/journal.pone.0235384
PMCID:
PMC7489500
AbstractArticlePDF–1.7M
6.
HSPA12A attenuates lipopolysaccharide-induced liver injury through inhibiting caspase-11-mediated hepatocyte pyroptosis via PGC-1α-dependent acyloxyacyl hydrolase expression
Jiali Liu, Shuya Du, Qiuyue Kong, Xiaojin Zhang, Surong Jiang, Xiaofei Cao, Yuehua Li, Chuanfu Li, Huaqun Chen, Zhengnian Ding, Li Liu
Cell Death Differ. 2020 Sep; 27(9): 2651–2667. Published online 2020 Apr 24. doi: 10.1038/s41418-020-0536-x
PMCID:
PMC7429872
AbstractArticlePDF–4.3M
7.
Acyloxyacyl hydrolase regulates voiding activity
Lizath M. Aguiniga, Timothy J. Searl, Afrida Rahman-Enyart, Ryan E. Yaggie, Wenbin Yang, Anthony J. Schaeffer, David J. Klumpp
Am J Physiol Renal Physiol. 2020 Apr 1; 318(4): F1006–F1016. Published online 2020 Jan 31. doi: 10.1152/ajprenal.00442.2019
PMCID:
PMC7191453
AbstractArticle
8.
Acyloxyacyl hydrolase modulates depressive-like behaviors through aryl hydrocarbon receptor
Lizath M. Aguiniga, Wenbin Yang, Ryan E. Yaggie, Anthony J. Schaeffer, David J. Klumpp, MAPP Research Network Study Group
Am J Physiol Regul Integr Comp Physiol. 2019 Aug 1; 317(2): R289–R300. Published online 2019 Apr 24. doi: 10.1152/ajpregu.00029.2019
PMCID:
PMC6732428
AbstractArticle
9.
LPS inactivation by a host lipase allows lung epithelial cell sensitization for allergic asthma
Guojun Qian, Wei Jiang, Benkun Zou, Jintao Feng, Xiaofang Cheng, Jie Gu, Tianqing Chu, Chen Niu, Rui He, Yiwei Chu, Mingfang Lu
J Exp Med. 2018 Sep 3; 215(9): 2397–2412. doi: 10.1084/jem.20172225
PMCID:
PMC6122967
AbstractArticlePDF–3.1M
10.
Acyloxyacyl hydrolase modulates pelvic pain severity
Wenbin Yang, Ryan E. Yaggie, Mingchen C. Jiang, Charles N. Rudick, Joseph Done, Charles J. Heckman, John M. Rosen, Anthony J. Schaeffer, David J. Klumpp
Am J Physiol Regul Integr Comp Physiol. 2018 Mar 1; 314(3): R353–R365. Published online 2017 Nov 8. doi: 10.1152/ajpregu.00239.2017
PMCID:
PMC5899250
AbstractArticle
11.
Crystal structure of the mammalian lipopolysaccharide detoxifier
Alexei Gorelik, Katalin Illes, Bhushan Nagar
Proc Natl Acad Sci U S A. 2018 Jan 30; 115(5): E896–E905. Published online 2018 Jan 17. doi: 10.1073/pnas.1719834115
PMCID:
PMC5798384
AbstractArticlePDF–2.4M
12.
Acyloxyacyl hydrolase promotes the resolution of lipopolysaccharide-induced acute lung injury
Benkun Zou, Wei Jiang, Han Han, Jing Li, Weiying Mao, Zihui Tang, Qian Yang, Guojun Qian, Jing Qian, Wenjiao Zeng, Jie Gu, Tianqing Chu, Ning Zhu, Wenhong Zhang, Dapeng Yan, Rui He, Yiwei Chu, Mingfang Lu
PLoS Pathog. 2017 Jun; 13(6): e1006436. Published online 2017 Jun 16. doi: 10.1371/journal.ppat.1006436
PMCID:
PMC5489216
AbstractArticlePDF–7.7M
13.
Sox4 Links Tumor Suppression to Accelerated Aging in Mice by Modulating Stem Cell Activation
Miguel Foronda, Paula Martínez, Stefan Schoeftner, Gonzalo Gómez-López, Ralph Schneider, Juana M. Flores, David G. Pisano, Maria A. Blasco
Cell Rep. Author manuscript; available in PMC 2016 Jun 13.
Published in final edited form as: Cell Rep. 2014 Jul 24; 8(2): 487–500. Published online 2014 Jul 17. doi: 10.1016/j.celrep.2014.06.031
PMCID:
PMC4905521
AbstractArticlePDF–2.8M
14.
Hepatic uptake and deacylation of the lipopolysaccharide in bloodborne lipopolysaccharide-lipoprotein complexes
Baomei Shao, Robert Munford, Richard L. Kitchens, Alan W. Varley
Innate Immun. Author manuscript; available in PMC 2014 Aug 4.
Published in final edited form as: Innate Immun. 2012 Dec; 18(6): 825–833. Published online 2012 Mar 22. doi: 10.1177/1753425912442431
PMCID:
PMC4120711
AbstractArticlePDF–2.3M
15.
Altered inactivation of commensal LPS due to acyloxyacyl hydrolase deficiency in colonic dendritic cells impairs mucosal Th17 immunity
Brian M. Janelsins, Mingfang Lu, Sandip K. Datta
Proc Natl Acad Sci U S A. 2014 Jan 7; 111(1): 373–378. Published online 2013 Dec 16. doi: 10.1073/pnas.1311987111
PMCID:
PMC3890863
AbstractArticlePDF–969K
16.
Persistently Active Microbial Molecules Prolong Innate Immune Tolerance In Vivo
Mingfang Lu, Alan W. Varley, Robert S. Munford
PLoS Pathog. 2013 May; 9(5): e1003339. Published online 2013 May 9. doi: 10.1371/journal.ppat.1003339
PMCID:
PMC3649966
AbstractArticlePDF–2.2M
17.
Prolonged hepatomegaly in mice that cannot inactivate bacterial endotoxin
Baomei Shao, Richard Kitchens, Robert Munford, Thomas E. Rogers, Don C. Rockey, Alan W. Varley
Hepatology. Author manuscript; available in PMC 2012 Sep 2.
Published in final edited form as: Hepatology. 2011 Sep 2; 54(3): 1051–1062. Published online 2011 Jul 27. doi: 10.1002/hep.24488
PMCID:
PMC3188384
AbstractArticlePDF–1.9M
18.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
19.
The Transport and Inactivation Kinetics of Bacterial Lipopolysaccharide Influence its Immunological Potency in vivo
Mingfang Lu, Robert S. Munford
J Immunol. Author manuscript; available in PMC 2012 Sep 15.
Published in final edited form as: J Immunol. 2011 Sep 15; 187(6): 3314–3320. Published online 2011 Aug 17. doi: 10.4049/jimmunol.1004087
PMCID:
PMC3169744
AbstractArticlePDF–1.6M
20.
A High-Resolution Anatomical Atlas of the Transcriptome in the Mouse Embryo
Graciana Diez-Roux, Sandro Banfi, Marc Sultan, Lars Geffers, Santosh Anand, David Rozado, Alon Magen, Elena Canidio, Massimiliano Pagani, Ivana Peluso, Nathalie Lin-Marq, Muriel Koch, Marchesa Bilio, Immacolata Cantiello, Roberta Verde, Cristian De Masi, Salvatore A. Bianchi, Juliette Cicchini, Elodie Perroud, Shprese Mehmeti, Emilie Dagand, Sabine Schrinner, Asja Nürnberger, Katja Schmidt, Katja Metz, Christina Zwingmann, Norbert Brieske, Cindy Springer, Ana Martinez Hernandez, Sarah Herzog, Frauke Grabbe, Cornelia Sieverding, Barbara Fischer, Kathrin Schrader, Maren Brockmeyer, Sarah Dettmer, Christin Helbig, Violaine Alunni, Marie-Annick Battaini, Carole Mura, Charlotte N. Henrichsen, Raquel Garcia-Lopez, Diego Echevarria, Eduardo Puelles, Elena Garcia-Calero, Stefan Kruse, Markus Uhr, Christine Kauck, Guangjie Feng, Nestor Milyaev, Chuang Kee Ong, Lalit Kumar, MeiSze Lam, Colin A. Semple, Attila Gyenesei, Stefan Mundlos, Uwe Radelof, Hans Lehrach, Paolo Sarmientos, Alexandre Reymond, Duncan R. Davidson, Pascal Dollé, Stylianos E. Antonarakis, Marie-Laure Yaspo, Salvador Martinez, Richard A. Baldock, Gregor Eichele, Andrea Ballabio
PLoS Biol. 2011 Jan; 9(1): e1000582. Published online 2011 Jan 18. doi: 10.1371/journal.pbio.1000582
PMCID:
PMC3022534
AbstractArticlePDF–3.8M

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