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Select item 109176601.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 108152482.

Nanxi Li, Peng Ren, Jingya Wang, Xiaohui Zhu, Xuan Qiao, Zhirui Zeng, Tong Ye, Shanshan Wang, Zhiyun Meng, Hui Gan, Shuchen Liu, Yunbo Sun, Xiaoxia Zhu, Guifang Dou, Ruolan Gu

Int J Mol Sci. 2024 Jan; 25(2): 749. Published online 2024 Jan 6. doi: 10.3390/ijms25020749

PMCID:: PMC10815248

Abstract Article PDF–10M

Select item 105924723.

Distinct bidirectional regulation of LFA1 and α4β7 by Rap1 and integrin adaptors in T cells under shear flow

Yuji Kamioka, Yoshihiro Ueda, Naoyuki Kondo, Keizo Tokuhiro, Yoshiki Ikeda, Wolfgang Bergmeier, Tatsuo Kinashi

Cell Rep. Author manuscript; available in PMC 2023 Oct 23.

Published in final edited form as: Cell Rep. 2023 Jun 27; 42(6): 112580. Published online 2023 Jun 1. doi: 10.1016/j.celrep.2023.112580

PMCID:: PMC10592472

Abstract Article PDF–2.2M

Select item 91331654.

Progressive skeletal defects caused by Kindlin3 deficiency, a model of autosomal recessive osteopetrosis in humans

Tejasvi Dudiki, Daniel W. Nascimento, Lauren S. Childs, Swetha Kareti, Charlie Androjna, Irina Zhevlakova, Tatiana V. Byzova

Bone. Author manuscript; available in PMC 2023 Jul 1.

Published in final edited form as: Bone. 2022 Jul; 160: 116397. Published online 2022 Mar 25. doi: 10.1016/j.bone.2022.116397

PMCID:: PMC9133165

Abstract Article PDF–2.7M

Select item 89865385.

Neutrophils direct preexisting matrix to initiate repair in damaged tissues

Adrian Fischer, Juliane Wannemacher, Simon Christ, Tim Koopmans, Safwen Kadri, Jiakuan Zhao, Mahesh Gouda, Haifeng Ye, Martin Mück-Häusl, Peter W. Krenn, Hans-Günther Machens, Reinhard Fässler, Philipp-Alexander Neumann, Stefanie M. Hauck, Yuval Rinkevich

Nat Immunol. 2022; 23(4): 518–531. Published online 2022 Mar 30. doi: 10.1038/s41590-022-01166-6

PMCID:: PMC8986538

Abstract Article PDF–18M

Select item 83132396.

Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development

Francesco Bedogni, Robert F. Hevner

Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034

PMCID:: PMC8313239

Abstract Article PDF–1.6M

Select item 79865767.

Kindlin-3 is essential for patrolling and phagocytosis functions of nonclassical monocytes during metastatic cancer surveillance

Paola M. Marcovecchio, Yanfang Peipei Zhu, Richard N. Hanna, Huy Q. Dinh, Robert Tacke, Runpei Wu, Sara McArdle, Sophia Reynolds, Daniel J. Araujo, Klaus Ley, Catherine C. Hedrick

J Leukoc Biol. Author manuscript; available in PMC 2021 Mar 23.

Published in final edited form as: J Leukoc Biol. 2020 Jun; 107(6): 883–892. Published online 2020 May 9. doi: 10.1002/JLB.4HI0420-098R

PMCID:: PMC7986576

Abstract Article PDF–1.5M

Select item 79387708.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 78745239.

Kindlin-3 Mutation in Mesenchymal Stem Cells Results in Enhanced Chondrogenesis

Bethany A. Kerr, Lihong Shi, Alexander H. Jinnah, Koran S. Harris, Jeffrey S. Willey, Donald P. Lennon, Arnold I. Caplan, Tatiana V. Byzova

Exp Cell Res. Author manuscript; available in PMC 2022 Feb 15.

Published in final edited form as: Exp Cell Res. 2021 Feb 15; 399(2): 112456. Published online 2021 Jan 5. doi: 10.1016/j.yexcr.2020.112456

PMCID:: PMC7874523

Abstract Article PDF–3.0M

Select item 780801210.

Kindlin-3 recruitment to the plasma membrane precedes high-affinity β₂-integrin and neutrophil arrest from rolling

Lai Wen, Alex Marki, Payel Roy, Sara McArdle, Hao Sun, Zhichao Fan, Alexandre R. Gingras, Mark H. Ginsberg, Klaus Ley

Blood. 2021 Jan 7; 137(1): 29–38. Prepublished online 2020 Aug 10. doi: 10.1182/blood.2019003446

PMCID:: PMC7808012

Abstract Article

Select item 753367611.

Kindlin-3 loss curbs chronic myeloid leukemia in mice by mobilizing leukemic stem cells from protective bone marrow niches

Peter William Krenn, Steffen Koschmieder, Reinhard Fässler

Proc Natl Acad Sci U S A. 2020 Sep 29; 117(39): 24326–24335. Published online 2020 Sep 14. doi: 10.1073/pnas.2009078117

PMCID:: PMC7533676

Abstract Article PDF–1.9M

Select item 741599112.

BioID screening of biotinylation sites using the avidin-like protein Tamavidin 2-REV identifies global interactors of stimulator of interferon genes (STING)

Kou Motani, Hidetaka Kosako

J Biol Chem. 2020 Aug 7; 295(32): 11174–11183. Published online 2020 Jun 17. doi: 10.1074/jbc.RA120.014323

PMCID:: PMC7415991

Abstract Article PDF–2.0M

Select item 703310613.

Microglia control vascular architecture via a TGFβ1 dependent paracrine mechanism linked to tissue mechanics

Tejasvi Dudiki, Julia Meller, Gautam Mahajan, Huan Liu, Irina Zhevlakova, Samantha Stefl, Conner Witherow, Eugene Podrez, Chandrasekhar R. Kothapalli, Tatiana V. Byzova

Nat Commun. 2020; 11: 986. Published online 2020 Feb 20. doi: 10.1038/s41467-020-14787-y

PMCID:: PMC7033106

Abstract Article PDF–6.0M

Select item 690880614.

Eosinophil-platelet interactions promote atherosclerosis and stabilize thrombosis with eosinophil extracellular traps

Charlotte Marx, Julia Novotny, Danby Salbeck, Katie R. Zellner, Leo Nicolai, Kami Pekayvaz, Badr Kilani, Sven Stockhausen, Niklas Bürgener, Danny Kupka, Thomas J. Stocker, Ludwig T. Weckbach, Joachim Pircher, Markus Moser, Michael Joner, Walter Desmet, Tom Adriaenssens, Franz-Josef Neumann, Anthony H. Gerschlick, Jurrien M. ten Berg, Michael Lorenz, Konstantin Stark

Blood. 2019 Nov 21; 134(21): 1859–1872. Prepublished online 2019 Sep 3. doi: 10.1182/blood.2019000518

PMCID:: PMC6908806

Abstract Article

Select item 678144915.

A kindlin-3–leupaxin–paxillin signaling pathway regulates podosome stability

Sarah Klapproth, Thomas Bromberger, Clara Türk, Marcus Krüger, Markus Moser

J Cell Biol. 2019 Oct 7; 218(10): 3436–3454. Published online 2019 Sep 19. doi: 10.1083/jcb.201903109

PMCID:: PMC6781449

Abstract Article PDF–6.0M

Select item 675689216.

Kindlin-3 in platelets and myeloid cells differentially regulates deep vein thrombosis in mice

Yanyan Yan, Hongqin Yang, Xiao Hu, Zeping Zhang, Shushu Ge, Zhen Xu, Juan Gao, Junling Liu, Gilbert C. White, Yan-Qing Ma

Aging (Albany NY) 2019 Sep 15; 11(17): 6951–6959. Published online 2019 Aug 31. doi: 10.18632/aging.102229

PMCID:: PMC6756892

Abstract Article PDF–1.9M

Select item 654682717.

A β2-Integrin/MRTF-A/SRF Pathway Regulates Dendritic Cell Gene Expression, Adhesion, and Traction Force Generation

Carla Guenther, Imrul Faisal, Liisa M. Uotila, Marc Llort Asens, Heidi Harjunpää, Terhi Savinko, Tiina Öhman, Sean Yao, Markus Moser, Stephan W. Morris, Sari Tojkander, Susanna Carola Fagerholm

Front Immunol. 2019; 10: 1138. Published online 2019 May 28. doi: 10.3389/fimmu.2019.01138

PMCID:: PMC6546827

Abstract Article PDF–7.6M

Select item 638111218.

Kindlin-2 links mechano-environment to proline synthesis and tumor growth

Ling Guo, Chunhong Cui, Kuo Zhang, Jiaxin Wang, Yilin Wang, Yixuan Lu, Ka Chen, Jifan Yuan, Guozhi Xiao, Bin Tang, Ying Sun, Chuanyue Wu

Nat Commun. 2019; 10: 845. Published online 2019 Feb 19. doi: 10.1038/s41467-019-08772-3

PMCID:: PMC6381112

Abstract Article PDF–8.7M

Select item 633346019.

ATG5 is required for B cell polarization and presentation of particulate antigens

Florent Arbogast, Johan Arnold, Philippe Hammann, Lauriane Kuhn, Johana Chicher, Diane Murera, Justine Weishaar, Sylviane Muller, Jean-Daniel Fauny, Frédéric Gros

Autophagy. 2019; 15(2): 280–294. Published online 2018 Sep 22. doi: 10.1080/15548627.2018.1516327

PMCID:: PMC6333460

Abstract Article PDF–2.7M

Select item 612691920.

Differential requirement of kindlin-3 for T cell progenitor homing to the non-vascularized and vascularized thymus

Federico Andrea Moretti, Sarah Klapproth, Raphael Ruppert, Andreas Margraf, Jasmin Weber, Robert Pick, Christoph Scheiermann, Markus Sperandio, Reinhard Fässler, Markus Moser

eLife. 2018; 7: e35816. Published online 2018 Sep 6. doi: 10.7554/eLife.35816

PMCID:: PMC6126919

Abstract Article PDF–9.2M

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