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Items: 1 to 20 of 90

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
IQGAP1 promotes chronic pain by regulating the trafficking and sensitization of TRPA1 channels
Shakil Khan, Pabitra Hriday Patra, Hannah Somerfield, Hattaya Benya-Aphikul, Manoj Upadhya, Xuming Zhang
Brain. 2023 Jun; 146(6): 2595–2611. Published online 2022 Dec 7. doi: 10.1093/brain/awac462
PMCID:
PMC10232262
AbstractArticlePDF–1.7M
3.
SVEP1 is an endogenous ligand for the orphan receptor PEAR1
Jared S. Elenbaas, Upasana Pudupakkam, Katrina J. Ashworth, Chul Joo Kang, Ved Patel, Katherine Santana, In-Hyuk Jung, Paul C. Lee, Kendall H. Burks, Junedh M. Amrute, Robert P. Mecham, Carmen M. Halabi, Arturo Alisio, Jorge Di Paola, Nathan O. Stitziel
Nat Commun. 2023; 14: 850. Published online 2023 Feb 15. doi: 10.1038/s41467-023-36486-0
Correction in:
Nat Commun. 2023; 14: 1511.
PMCID:
PMC9932102
AbstractArticlePDF–8.9M
4.
The Ras GTPase‐activating‐like protein IQGAP1 bridges Gasdermin D to the ESCRT system to promote IL‐1β release via exosomes
Yun Liao, Xing Chen, William Miller‐Little, Han Wang, Belinda Willard, Katarzyna Bulek, Junjie Zhao, Xiaoxia Li
EMBO J. 2023 Jan; 42(1): e110780. Published online 2022 Nov 14. doi: 10.15252/embj.2022110780
PMCID:
PMC9811620
AbstractArticlePDF–17M
5.
Identification of IQGAP1 as a SLC26A4 (Pendrin)-Binding Protein in the Kidney
Jie Xu, Sharon Barone, Mujan Varasteh Kia, L. Shannon Holliday, Kamyar Zahedi, Manoocher Soleimani
Front Mol Biosci. 2022; 9: 874186. Published online 2022 May 5. doi: 10.3389/fmolb.2022.874186
PMCID:
PMC9117723
AbstractArticlePDF–2.5M
6.
Active Rap1-mediated Inhibition of Choroidal Neovascularization Requires Interactions with IQGAP1 in Choroidal Endothelial Cells
Aniket Ramshekar, Haibo Wang, Eric Kunz, Christian Pappas, Gregory S. Hageman, Brahim Chaqour, David B. Sacks, M. Elizabeth Hartnett
FASEB J. Author manuscript; available in PMC 2022 Jul 1.
Published in final edited form as: FASEB J. 2021 Jul; 35(7): e21642. doi: 10.1096/fj.202100112R
PMCID:
PMC8238370
AbstractArticlePDF–1.7M
7.
Proteotyping of knockout mouse strains reveals sex- and strain-specific signatures in blood plasma
Yassene Mohammed, Sarah A. Michaud, Helena Pětrošová, Juncong Yang, Milan Ganguly, David Schibli, Ann M. Flenniken, Lauryl M. J. Nutter, Hibret A. Adissu, K. C. Kent Lloyd, Colin McKerlie, Christoph H. Borchers
NPJ Syst Biol Appl. 2021; 7: 25. Published online 2021 May 28. doi: 10.1038/s41540-021-00184-8
PMCID:
PMC8163790
AbstractArticlePDF–6.9M
8.
Scaffolding Protein IQGAP1 Is Dispensable, but Its Overexpression Promotes Hepatocellular Carcinoma via YAP1 Signaling
Evan R. Delgado, Hanna L. Erickson, Junyan Tao, Satdarshan P. Monga, Andrew W. Duncan, Sayeepriyadarshini Anakk
Mol Cell Biol. 2021 Apr; 41(4): e00596-20. Prepublished online 2021 Feb 1. Published online 2021 Mar 24. doi: 10.1128/MCB.00596-20
PMCID:
PMC8088129
AbstractArticlePDF–4.6M
9.
IQGAP1 binds AMPK and is required for maximum AMPK activation
Andrew C. Hedman, Zhigang Li, Laëtitia Gorisse, Swetha Parvathaneni, Chase J. Morgan, David B. Sacks
J Biol Chem. 2021 Jan-Jun; 296: 100075. Published online 2020 Nov 21. doi: 10.1074/jbc.RA120.016193
PMCID:
PMC7948462
AbstractArticlePDF–2.3M
10.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
11.
IQGAP1 Causes Choroidal Neovascularization by Sustaining VEGFR2-mediated Rac1 Activation
Haibo Wang, Aniket Ramshekar, Eric Kunz, David B Sacks, M. Elizabeth Hartnett
Angiogenesis. Author manuscript; available in PMC 2021 Nov 1.
Published in final edited form as: Angiogenesis. 2020 Nov; 23(4): 685–698. Published online 2020 Aug 11. doi: 10.1007/s10456-020-09740-y
PMCID:
PMC7530064
AbstractArticlePDF–2.5M
12.
Flightless anchors IQGAP1 and R-ras to mediate cell extension formation and matrix remodeling
P. D. Arora, K. Nakajima, A. Nanda, A. Plaha, A. Wilde, D. B. Sacks, C. A. McCulloch
Mol Biol Cell. 2020 Jul 15; 31(15): 1595–1610. doi: 10.1091/mbc.E19-10-0554
PMCID:
PMC7521798
AbstractArticlePDF–4.7M
13.
Methyltransferase-like 21e inhibits 26S proteasome activity to facilitate hypertrophy of type IIb myofibers
Chao Wang, Bin Zhang, Anna C. Ratliff, Justine Arrington, Jingjuan Chen, Yan Xiong, Feng Yue, Yaohui Nie, Keping Hu, Wen Jin, W. Andy Tao, Christine A. Hrycyna, Xiaobo Sun, Shihuan Kuang
FASEB J. 2019 Aug; 33(8): 9672–9684. Published online 2019 Jun 4. doi: 10.1096/fj.201900582R
PMCID:
PMC6993925
AbstractArticle
14.
Endothelial IQGAP1 regulates leukocyte transmigration by directing the LBRC to the site of diapedesis
David P. Sullivan, Prarthana J. Dalal, Fanny Jaulin, David B. Sacks, Geri Kreitzer, William A. Muller
J Exp Med. 2019 Nov 4; 216(11): 2582–2601. Published online 2019 Aug 8. doi: 10.1084/jem.20190008
PMCID:
PMC6829592
AbstractArticlePDF–3.9M
15.
Single-Cell Analysis of the Liver Epithelium Reveals Dynamic Heterogeneity and an Essential Role for YAP in Homeostasis and Regeneration
Brian J. Pepe-Mooney, Michael T. Dill, Anna Alemany, Jose Ordovas-Montanes, Yuki Matsushita, Anuradha Rao, Anushna Sen, Makoto Miyazaki, Sayeepriyadarshini Anakk, Paul A. Dawson, Noriaki Ono, Alex K. Shalek, Alexander van Oudenaarden, Fernando D. Camargo
Cell Stem Cell. Author manuscript; available in PMC 2020 Jul 3.
Published in final edited form as: Cell Stem Cell. 2019 Jul 3; 25(1): 23–38.e8. Published online 2019 May 9. doi: 10.1016/j.stem.2019.04.004
PMCID:
PMC6814390
AbstractArticlePDF–5.7M
16.
Protein prenylation restrains innate immunity by inhibiting Rac1 effector interactions
Murali K. Akula, Mohamed X. Ibrahim, Emil G. Ivarsson, Omar M. Khan, Israiel T. Kumar, Malin Erlandsson, Christin Karlsson, Xiufeng Xu, Mikael Brisslert, Cord Brakebusch, Donghai Wang, Maria Bokarewa, Volkan I. Sayin, Martin O. Bergo
Nat Commun. 2019; 10: 3975. Published online 2019 Sep 4. doi: 10.1038/s41467-019-11606-x
PMCID:
PMC6726657
AbstractArticlePDF–1.4M
17.
Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics
Joel D. Federspiel, Todd M. Greco, Krystal K. Lum, Ileana M. Cristea
Mol Cell Proteomics. 2019 Aug 9; 18(8 Suppl 1): S92–S113. Published online 2019 Apr 30. doi: 10.1074/mcp.RA118.001253
PMCID:
PMC6692770
AbstractArticlePDF–7.7M
18.
IQGAP1 Regulates Adult Neural Progenitors In Vivo and Vascular Endothelial Growth Factor-Triggered Neural Progenitor Migration In Vitro
Laurent Balenci, Yasmina Saoudi, Didier Grunwald, Jean Christophe Deloulme, Alexandre Bouron, André Bernards, Jacques Baudier
J Neurosci. 2007 Apr 25; 27(17): 4716–4724. doi: 10.1523/JNEUROSCI.0830-07.2007
PMCID:
PMC6672986
AbstractArticlePDF–681K
19.
WDFY4 is required for cross-presentation in response to viral and tumor antigens
Derek J. Theisen, Jesse T. Davidson, IV, Carlos G. Briseño, Marco Gargaro, Elvin J. Lauron, Qiuling Wang, Pritesh Desai, Vivek Durai, Prachi Bagadia, Joshua R. Brickner, Wandy L. Beatty, Herbert W. Virgin, William E. Gillanders, Nima Mosammaparast, Michael S. Diamond, L. David Sibley, Wayne Yokoyama, Robert D. Schreiber, Theresa L. Murphy, Kenneth M. Murphy
Science. Author manuscript; available in PMC 2019 Jul 24.
Published in final edited form as: Science. 2018 Nov 9; 362(6415): 694–699. doi: 10.1126/science.aat5030
PMCID:
PMC6655551
AbstractArticlePDF–1020K
20.
Postnatal liver functional maturation requires Cnot complex-mediated decay of mRNAs encoding cell cycle and immature liver genes
Toru Suzuki, Chisato Kikuguchi, Saori Nishijima, Takeshi Nagashima, Akinori Takahashi, Mariko Okada, Tadashi Yamamoto
Development. 2019 Feb 15; 146(4): dev168146. Published online 2019 Feb 15. doi: 10.1242/dev.168146
PMCID:
PMC6398447
AbstractArticle

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