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Items: 1 to 20 of 69

1.
The midnolin-proteasome pathway catches proteins for ubiquitination-independent degradation
Xin Gu, Christopher Nardone, Nolan Kamitaki, Aoyue Mao, Stephen J. Elledge, Michael E. Greenberg
Science. Author manuscript; available in PMC 2023 Oct 31.
Published in final edited form as: Science. 2023 Aug 25; 381(6660): eadh5021. Published online 2023 Aug 25. doi: 10.1126/science.adh5021
PMCID:
PMC10617673
ArticlePDF–3.6M
2.
C5orf51 is a component of the MON1-CCZ1 complex and controls RAB7A localization and stability during mitophagy
Bing-Ru Yan, Taoyingnan Li, Etienne Coyaud, Estelle M. N. Laurent, Jonathan St-Germain, Yuhuan Zhou, Peter K. Kim, Brian Raught, John H. Brumell
Autophagy. 2022; 18(4): 829–840. Published online 2021 Aug 25. doi: 10.1080/15548627.2021.1960116
PMCID:
PMC9037554
ArticlePDF–4.1M
3.
SLC1A1 mediated glutamine addiction and contributed to natural killer T-cell lymphoma progression with immunotherapeutic potential
Jie Xiong, Nan Wang, Hui-Juan Zhong, Bo-Wen Cui, Shu Cheng, Rui Sun, Jia-Yi Chen, Peng-Peng Xu, Gang Cai, Li Wang, Xiao-Jian Sun, Jin-Yan Huang, Wei-Li Zhao
EBioMedicine. 2021 Oct; 72: 103614. Published online 2021 Oct 7. doi: 10.1016/j.ebiom.2021.103614
PMCID:
PMC8511843
ArticlePDF–4.1M
4.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
ArticlePDF–2.2M
5.
Cryo-EM structures of excitatory amino acid transporter 3 visualize coupled substrate, sodium, and proton binding and transport
Biao Qiu, Doreen Matthies, Eva Fortea, Zhiheng Yu, Olga Boudker
Sci Adv. 2021 Mar; 7(10): eabf5814. Published online 2021 Mar 3. doi: 10.1126/sciadv.abf5814
PMCID:
PMC7929514
ArticlePDF–667K
6.
Neuregulin-1 inhibits CoCl2-induced upregulation of excitatory amino acid carrier 1 expression and oxidative stress in SH-SY5Y cells and the hippocampus of mice
Han-Byeol Kim, Ji-Young Yoo, Seung-Yeon Yoo, Jun-Ho Lee, Wonseok Chang, Hye-Sun Kim, Tai-Kyoung Baik, Ran-Sook Woo
Mol Brain. 2020; 13: 153. Published online 2020 Nov 13. doi: 10.1186/s13041-020-00686-2
PMCID:
PMC7664014
ArticlePDF–2.1M
7.
Gateways for Glutamate Neuroprotection in Parkinson’s Disease (PD): Essential Role of EAAT3 and NCX1 Revealed in an In Vitro Model of PD
Silvia Piccirillo, Simona Magi, Alessandra Preziuso, Pasqualina Castaldo, Salvatore Amoroso, Vincenzo Lariccia
Cells. 2020 Sep; 9(9): 2037. Published online 2020 Sep 6. doi: 10.3390/cells9092037
PMCID:
PMC7563499
ArticlePDF–2.7M
8.
SLC1A1, SLC16A9, and CNTN3 Are Potential Biomarkers for the Occurrence of Colorectal Cancer
Jie Zhou, Zhiman Xie, Ping Cui, Qisi Su, Yu Zhang, Lijia Luo, Zhuoxin Li, Li Ye, Hao Liang, Jiegang Huang
Biomed Res Int. 2020; 2020: 1204605. Published online 2020 May 23. doi: 10.1155/2020/1204605
PMCID:
PMC7273407
ArticlePDF–5.4M
9.
A reference map of the human binary protein interactome
Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood
Nature. Author manuscript; available in PMC 2020 Oct 8.
Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x
PMCID:
PMC7169983
ArticlePDF–5.4M
10.
Glutamate transporter SLC1A1 is associated with clear cell renal cell carcinoma
Sercan ERGÜN, Sezgin GÜNEŞ, Recep BÜYÜKALPELLİ, Oğuz AYDIN
Turk J Med Sci. 2019; 49(2): 531–537. Published online 2019 Apr 18. doi: 10.3906/sag-1808-130
PMCID:
PMC7024430
ArticlePDF–926K
11.
Extensive disruption of protein interactions by genetic variants across the allele frequency spectrum in human populations
Robert Fragoza, Jishnu Das, Shayne D. Wierbowski, Jin Liang, Tina N. Tran, Siqi Liang, Juan F. Beltran, Christen A. Rivera-Erick, Kaixiong Ye, Ting-Yi Wang, Li Yao, Matthew Mort, Peter D. Stenson, David N. Cooper, Xiaomu Wei, Alon Keinan, John C. Schimenti, Andrew G. Clark, Haiyuan Yu
Nat Commun. 2019; 10: 4141. Published online 2019 Sep 12. doi: 10.1038/s41467-019-11959-3
PMCID:
PMC6742646
ArticlePDF–1.2M
12.
Phorbol Myristate Acetate-Dependent Interaction of Protein Kinase Cα and the Neuronal Glutamate Transporter EAAC1
Marco I. González, Peter G. Bannerman, Michael B. Robinson
J Neurosci. 2003 Jul 2; 23(13): 5589–5593. doi: 10.1523/JNEUROSCI.23-13-05589.2003
PMCID:
PMC6741220
ArticlePDF–317K
13.
Small-Scale Molecular Motions Accomplish Glutamate Uptake in Human Glutamate Transporters
Hans P. Koch, H. Peter Larsson
J Neurosci. 2005 Feb 16; 25(7): 1730–1736. doi: 10.1523/JNEUROSCI.4138-04.2005
PMCID:
PMC6725926
ArticlePDF–245K
14.
The Glutamate and Chloride Permeation Pathways Are Colocalized in Individual Neuronal Glutamate Transporter Subunits
Gregory P. Leary, Emily F. Stone, David C. Holley, Michael P. Kavanaugh
J Neurosci. 2007 Mar 14; 27(11): 2938–2942. doi: 10.1523/JNEUROSCI.4851-06.2007
PMCID:
PMC6672579
ArticlePDF–205K
15.
EAAC1 Gene Deletion Alters Zinc Homeostasis and Exacerbates Neuronal Injury after Transient Cerebral Ischemia
Seok Joon Won, Byung Hoon Yoo, Angela M. Brennan, Byung Seop Shin, Tiina M. Kauppinen, Ari E. Berman, Raymond A. Swanson, Sang Won Suh
J Neurosci. 2010 Nov 17; 30(46): 15409–15418. doi: 10.1523/JNEUROSCI.2084-10.2010
PMCID:
PMC6633677
ArticlePDF–2.9M
16.
Functional comparisons of three glutamate transporter subtypes cloned from human motor cortex
JL Arriza, WA Fairman, JI Wadiche, GH Murdoch, MP Kavanaugh, SG Amara
J Neurosci. 1994 Sep 1; 14(9): 5559–5569. doi: 10.1523/JNEUROSCI.14-09-05559.1994
PMCID:
PMC6577102
AbstractPDF–1.6M
17.
Brief Report: Functional Studies and Rare Variant Screening of SLC1A1/EAAC1 in Males with Obsessive-Compulsive Disorder
Jeremy Veenstra-VanderWeele, Tim Xu, Alicia M. Ruggiero, Lauren R. Anderson, Shaine T. Jones, Joseph A. Himle, James L. Kennedy, Margaret A. Richter, Gregory L. Hanna, Paul D. Arnold
Psychiatr Genet. Author manuscript; available in PMC 2019 Apr 28.
Published in final edited form as: Psychiatr Genet. 2012 Oct; 22(5): 256–260. doi: 10.1097/YPG.0b013e328353fb63
PMCID:
PMC6486951
ArticlePDF–465K
18.
SorCS2 Controls Functional Expression of Amino Acid Transporter EAAT3 and Protects Neurons from Oxidative Stress and Epilepsy-Induced Pathology
Anna R. Malik, Kinga Szydlowska, Karolina Nizinska, Antonino Asaro, Erwin A. van Vliet, Oliver Popp, Gunnar Dittmar, Raphaela Fritsche-Guenther, Jennifer A. Kirwan, Anders Nykjaer, Katarzyna Lukasiuk, Eleonora Aronica, Thomas E. Willnow
Cell Rep. 2019 Mar 5; 26(10): 2792–2804.e6. Published online 2019 Mar 5. doi: 10.1016/j.celrep.2019.02.027
PMCID:
PMC6410498
Article
19.
Blood-Brain Barrier: From Physiology to Disease and Back
Melanie D. Sweeney, Zhen Zhao, Axel Montagne, Amy R. Nelson, Berislav V. Zlokovic
Physiol Rev. 2019 Jan 1; 99(1): 21–78. Published online 2018 Oct 3. doi: 10.1152/physrev.00050.2017
PMCID:
PMC6335099
Article
20.
Glutathione in Cellular Redox Homeostasis: Association with the Excitatory Amino Acid Carrier 1 (EAAC1)
Koji Aoyama, Toshio Nakaki
Molecules. 2015 May; 20(5): 8742–8758. Published online 2015 May 14. doi: 10.3390/molecules20058742
PMCID:
PMC6272787
ArticlePDF–1.3M

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