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Select item 91022691.

Is P-Glycoprotein Functionally Expressed in the Limiting Membrane of Endolysosomes? A Biochemical and Ultrastructural Study in the Rat Liver

Birthe Gericke, Inka Wienböker, Gudrun Brandes, Wolfgang Löscher

Cells. 2022 May; 11(9): 1556. Published online 2022 May 5. doi: 10.3390/cells11091556

PMCID:: PMC9102269

Abstract Article PDF–4.1M

Select item 88845072.

Sex-specific and concentration-dependent influence of Cremophor RH 40 on ampicillin absorption via its effect on intestinal membrane transporters in rats

Heyue Yin, Haibin Shao, Jing Liu, Yujia Qin, Wenbin Deng

PLoS One. 2022; 17(2): e0263692. Published online 2022 Feb 28. doi: 10.1371/journal.pone.0263692

PMCID:: PMC8884507

Abstract Article PDF–1.4M

Select item 86536103.

P-gp expression inhibition mediates placental glucocorticoid barrier opening and fetal weight loss

Caiyun Ge, Dan Xu, Pengxia Yu, Man Fang, Juanjuan Guo, Dan Xu, Yuan Qiao, Sijia Chen, Yuanzhen Zhang, Hui Wang

BMC Med. 2021; 19: 311. Published online 2021 Dec 8. doi: 10.1186/s12916-021-02173-4

Correction in:: BMC Med. 2022; 20: 126.

PMCID:: PMC8653610

Abstract Article PDF–6.9M

Select item 85638814.

Bile duct ligation causes opposite impacts on the expression and function of BCRP and P-gp in rat brain partly via affecting membrane expression of ezrin/radixin/moesin proteins

Tong Wu, Yun Sheng, Yuan-yuan Qin, Wei-min Kong, Meng-meng Jin, Han-yu Yang, Xiao-ke Zheng, Chang Dai, Ming Liu, Xiao-dong Liu, Li Liu

Acta Pharmacol Sin. 2021 Nov; 42(11): 1942–1950. Published online 2021 Feb 8. doi: 10.1038/s41401-020-00602-3

PMCID:: PMC8563881

Abstract Article PDF–1.7M

Select item 82770735.

Metabolomic and transcriptomic analysis reveals endogenous substrates and metabolic adaptation in rats lacking Abcg2 and Abcb1a transporters

Samit Ganguly, David Finkelstein, Timothy I. Shaw, Ryan D. Michalek, Kimberly M. Zorn, Sean Ekins, Kazuto Yasuda, Yu Fukuda, John D. Schuetz, Kamalika Mukherjee, Erin G. Schuetz

PLoS One. 2021; 16(7): e0253852. Published online 2021 Jul 13. doi: 10.1371/journal.pone.0253852

PMCID:: PMC8277073

Abstract Article PDF–3.6M

Select item 77803016.

Alcohol and Cocaine Exposure Modulates ABCB1 and ABCG2 Transporters in Male Alcohol-Preferring Rats

Alaa M. Hammad, Fawaz Alasmari, Youssef Sari, F. Scott Hall, Amit K. Tiwari

Mol Neurobiol. Author manuscript; available in PMC 2021 Jan 4.

Published in final edited form as: Mol Neurobiol. 2019 Mar; 56(3): 1921–1932. Published online 2018 Jul 6. doi: 10.1007/s12035-018-1153-2

PMCID:: PMC7780301

Abstract Article PDF–913K

Select item 62730547.

The Alterations in the Expression and Function of P-Glycoprotein in Vitamin A-Deficient Rats as well as the Effect of Drug Disposition in Vivo

Yubang Wang, Heng Qin, Chengxiang Zhang, Fei Huan, Ting Yan, Lulu Zhang

Molecules. 2016 Jan; 21(1): 46. Published online 2015 Dec 29. doi: 10.3390/molecules21010046

PMCID:: PMC6273054

Abstract Article PDF–1.0M

Select item 61519908.

Effects of P-Glycoprotein on the Transport of DL0410, a Potential Multifunctional Anti-Alzheimer Agent

Xiaocong Pang, Lin Wang, De Kang, Ying Zhao, Song Wu, Ai-Lin Liu, Guan-Hua Du

Molecules. 2017 Aug; 22(8): 1246. Published online 2017 Jul 25. doi: 10.3390/molecules22081246

PMCID:: PMC6151990

Abstract Article PDF–5.4M

Select item 57356539.

Upregulations of Clcn3 and P-Gp Provoked by Lens Osmotic Expansion in Rat Galactosemic Cataract

Lixia Ji, Lixia Cheng, Zhihong Yang

J Diabetes Res. 2017; 2017: 3472735. Published online 2017 Nov 21. doi: 10.1155/2017/3472735

PMCID:: PMC5735653

Abstract Article PDF–3.1M

Select item 563698010.

Abcb1a and Abcb1b genes function differentially in blood–testis barrier dynamics in the rat

Linlin Su, Yan C Cheng, Will M Lee, Min Zhang, Fangfang Yang, Bin Zhao, Daishu Han, Yixun Liu, Dahai Hu

Cell Death Dis. 2017 Sep; 8(9): e3038. Published online 2017 Sep 7. doi: 10.1038/cddis.2017.435

PMCID:: PMC5636980

Abstract Article PDF–4.1M

Select item 560907311.

The drug transporter ABCB1 c.3435C>T SNP influences artemether–lumefantrine treatment outcome

Kinanga Kiaco, António Sebastião Rodrigues, Virgílio do Rosário, José Pedro Gil, Dinora Lopes

Malar J. 2017; 16: 383. Published online 2017 Sep 21. doi: 10.1186/s12936-017-2006-6

PMCID:: PMC5609073

Abstract Article PDF–950K

Select item 546491012.

Combination analysis of NOS3, ABCB1 and IL23R polymorphisms with alcohol-induced osteonecrosis of the femoral head risk in Chinese males

Yuan Wang, Xuejun Yang, Jianping Shi, Yan Zhao, Linlin Pan, Jinqiu Zhou, Guoqiang Wang, Jianzhong Wang

Oncotarget. 2017 May 16; 8(20): 33770–33778. Published online 2017 Apr 4. doi: 10.18632/oncotarget.16809

PMCID:: PMC5464910

Abstract Article PDF–1.6M

Select item 539702713.

Genetic and epigenetic changes in host ABCB1 influences malaria susceptibility to Plasmodium falciparum

Himanshu Gupta, Sima Chaudhari, Ayushi Rai, Smitha Bhat, Pratima K Sahu, Manjunath H. Hande, Sydney C. D’Souza, Umakanth Shashikiran, Kapaettu Satyamoorthy

PLoS One. 2017; 12(4): e0175702. Published online 2017 Apr 19. doi: 10.1371/journal.pone.0175702

PMCID:: PMC5397027

Abstract Article PDF–2.9M

Select item 536370814.

Ceramide 1-Phosphate Increases P-Glycoprotein Transport Activity at the Blood-Brain Barrier via Prostaglandin E2 Signaling

Emily V. Mesev, David S. Miller, Ronald E. Cannon

Mol Pharmacol. 2017 Apr; 91(4): 373–382. Published online 2017 Apr. doi: 10.1124/mol.116.107169

PMCID:: PMC5363708

Abstract Article PDF–1.8M

Select item 522855515.

Ouabain-induced alterations in ABCB1 of mesenteric lymph nodes and thymocytes of rats and mice

Daniel Boff Lima, Raphael Carmo Valente, Marcia Alves Marques Capella

Oncol Lett. 2016 Dec; 12(6): 5275–5280. Published online 2016 Nov 8. doi: 10.3892/ol.2016.5366

PMCID:: PMC5228555

Abstract Article PDF–435K

Select item 520744516.

Effects on P-Glycoprotein Expression after Blood-Brain Barrier Disruption Using Focused Ultrasound and Microbubbles

Muna Aryal, Krisztina Fischer, Caroline Gentile, Salvatore Gitto, Yong-Zhi Zhang, Nathan McDannold

PLoS One. 2017; 12(1): e0166061. Published online 2017 Jan 3. doi: 10.1371/journal.pone.0166061

PMCID:: PMC5207445

Abstract Article PDF–1.4M

Select item 503191817.

P-glycoprotein (ABCB1) activity decreases raltegravir disposition in primary CD4+P-gp^high cells and correlates with HIV-1 viral load

Gerard Minuesa, Cristina Arimany-Nardi, Itziar Erkizia, Samandhy Cedeño, José Moltó, Bonaventura Clotet, Marçal Pastor-Anglada, Javier Martinez-Picado

J Antimicrob Chemother. 2016 Oct; 71(10): 2782–2792. Published online 2016 Jun 21. doi: 10.1093/jac/dkw215