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Select item 109176601.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 108534532.

Dbx1 is a dorsal midbrain-specific determinant of GABAergic neuron fate and regulates differentiation of the dorsal midbrain into the inferior and superior colliculi

Hong-Nhung Tran, Quy-Hoai Nguyen, Yongsu Jeong

Front Cell Dev Biol. 2024; 12: 1336308. Published online 2024 Jan 26. doi: 10.3389/fcell.2024.1336308

PMCID:: PMC10853453

Abstract Article PDF–8.4M

Select item 102536673.

The Midbrain Preisthmus: A Poorly Known Effect of the Isthmic Organizer

Luis Puelles, Matias Hidalgo-Sánchez

Int J Mol Sci. 2023 Jun; 24(11): 9769. Published online 2023 Jun 5. doi: 10.3390/ijms24119769

PMCID:: PMC10253667

Abstract Article PDF–6.8M

Select item 102089754.

TCF7L2 acts as a molecular switch in midbrain to control mammal vocalization through its DNA binding domain but not transcription activation domain

Huihui Qi, Li Luo, Caijing Lu, Runze Chen, Xianyao Zhou, Xiaohui Zhang, Yichang Jia

Mol Psychiatry. 2023; 28(4): 1703–1717. Published online 2023 Feb 13. doi: 10.1038/s41380-023-01993-5

Correction in:: Mol Psychiatry. 2023; 28(4): 1718.

PMCID:: PMC10208975

Abstract Article PDF–3.4M

Select item 101087075.

Canonical Wnt signaling regulates soft palate development by mediating ciliary homeostasis

Eva Janečková, Jifan Feng, Tingwei Guo, Xia Han, Aileen Ghobadi, Angelita Araujo-Villalba, Md Shaifur Rahman, Heliya Ziaei, Thach-Vu Ho, Siddhika Pareek, Jasmine Alvarez, Yang Chai

Development. 2023 Mar 1; 150(5): dev201189. Published online 2023 Mar 9. doi: 10.1242/dev.201189

PMCID:: PMC10108707

Abstract Article

Select item 100362876.

Tcf7l2 in hepatocytes regulates de novo lipogenesis in diet-induced non-alcoholic fatty liver disease in mice

Da Som Lee, Tae Hyeon An, Hyunmi Kim, Eunsun Jung, Gyeonghun Kim, Seung Yeon Oh, Jun Seok Kim, Hye Jin Chun, Jaeeun Jung, Eun-Woo Lee, Baek-Soo Han, Dai Hoon Han, Yong-Ho Lee, Tae-Su Han, Keun Hur, Chul-Ho Lee, Dae-Soo Kim, Won Kon Kim, Jun Won Park, Seung-Hoi Koo, Je Kyung Seong, Sang Chul Lee, Hail Kim, Kwang-Hee Bae, Kyoung-Jin Oh

Diabetologia. 2023; 66(5): 931–954. Published online 2023 Feb 10. doi: 10.1007/s00125-023-05878-8

PMCID:: PMC10036287

Abstract Article PDF–13M

Select item 98513887.

Habenular Tcf7l2 links nicotine addiction to diabetes

Alexander Duncan, Mary P. Heyer, Masago Ishikawa, Stephanie P. B. Caligiuri, Xin-an Liu, Zuxin Chen, Maria Vittoria di Bonaventura, Karim Elayouby, Jessica L. Ables, William M. Howe, Purva Bali, Clementine Fillinger, Maya Williams, Richard O’Connor, Zichen Wang, Qun Lu, Theodore M. Kamenecka, Avi Ma’ayan, Heidi C. O’Neill, Ines Ibanez-Tallon, Aron M. Geurts, Paul J. Kenny

Nature. Author manuscript; available in PMC 2023 Jan 19.

Published in final edited form as: Nature. 2019 Oct; 574(7778): 372–377. Published online 2019 Oct 16. doi: 10.1038/s41586-019-1653-x

PMCID:: PMC9851388

Abstract Article PDF–2.1M

Select item 97720708.

TCF7l2, a nuclear marker that labels premyelinating oligodendrocytes and promotes oligodendroglial lineage progression

Fuzheng Guo, Yan Wang

Glia. Author manuscript; available in PMC 2023 Feb 1.

Published in final edited form as: Glia. 2023 Feb; 71(2): 143–154. Published online 2022 Jul 16. doi: 10.1002/glia.24249

PMCID:: PMC9772070

Abstract Article PDF–2.7M

Select item 97206729.

Dentate gyrus morphogenesis is regulated by β-catenin function in hem-derived fimbrial glia

Arpan Parichha, Debarpita Datta, Varun Suresh, Mallika Chatterjee, Michael J. Holtzman, Shubha Tole

Development. 2022 Nov 1; 149(21): dev200953. Published online 2022 Oct 23. doi: 10.1242/dev.200953

PMCID:: PMC9720672

Abstract Article

Select item 968719610.

FGF9 Promotes Expression of HAS2 in Palatal Elevation via the Wnt/β-Catenin/TCF7L2 Pathway

Yidan Sun, Xiyu Ying, Ruomei Li, Mengjia Weng, Jiajun Shi, Zhenqi Chen

Biomolecules. 2022 Nov; 12(11): 1639. Published online 2022 Nov 4. doi: 10.3390/biom12111639

PMCID:: PMC9687196

Abstract Article PDF–2.4M

Select item 962437411.

TCF7L2 transcriptionally regulates Fgf15 to maintain bile acid and lipid homeostasis through gut-liver crosstalk

Neha Bhat, Fatemehsadat Esteghamat, Bal Krishna Chaube, Kushan Gunawardhana, Mitra Mani, Clay Thames, Dhanpat Jain, Henry N. Ginsberg, Carlos Fernandes-Hernando, Arya Mani

FASEB J. Author manuscript; available in PMC 2023 Mar 1.

Published in final edited form as: FASEB J. 2022 Mar; 36(3): e22185. doi: 10.1096/fj.202101607R

Correction in:: FASEB J. 2022 Mar; 36(3): e22217.

PMCID:: PMC9624374

Abstract Article PDF–4.1M

Select item 948196912.

Integrated analysis of Wnt signalling system component gene expression

Paula Murphy, Chris Armit, Bill Hill, Shanmugasundaram Venkataraman, Patrick Frankel, Richard A. Baldock, Duncan R. Davidson

Development. 2022 Aug 15; 149(16): dev200312. Published online 2022 Aug 15. doi: 10.1242/dev.200312

PMCID:: PMC9481969

Abstract Article

Select item 933435313.

Aberrant androgen action in prostatic progenitor cells induces oncogenesis and tumor development through IGF1 and Wnt axes

Won Kyung Kim, Adam W. Olson, Jiaqi Mi, Jinhui Wang, Dong-Hoon Lee, Vien Le, Alex Hiroto, Joseph Aldahl, Christian H. Nenninger, Alyssa J. Buckley, Robert Cardiff, Sungyong You, Zijie Sun

Nat Commun. 2022; 13: 4364. Published online 2022 Jul 28. doi: 10.1038/s41467-022-32119-0

PMCID:: PMC9334353

Abstract Article PDF–13M

Select item 929827714.

Olanzapine Promotes the Occurrence of Metabolic Disorders in Conditional TCF7L2-Knockout Mice

Ye Yang, Manjun Shen, Li Li, Yujun Long, Lu Wang, Bing Lang, Renrong Wu

Front Cell Dev Biol. 2022; 10: 890472. Published online 2022 Jul 6. doi: 10.3389/fcell.2022.890472

PMCID:: PMC9298277

Abstract Article PDF–2.5M

Select item 929666615.

A brain precursor atlas reveals the acquisition of developmental-like states in adult cerebral tumours

Akram A. Hamed, Daniel J. Kunz, Ibrahim El-Hamamy, Quang M. Trinh, Omar D. Subedar, Laura M. Richards, Warren Foltz, Garrett Bullivant, Matthaeus Ware, Maria C. Vladoiu, Jiao Zhang, Antony M. Raj, Trevor J. Pugh, Michael D. Taylor, Sarah A. Teichmann, Lincoln D. Stein, Benjamin D. Simons, Peter B. Dirks

Nat Commun. 2022; 13: 4178. Published online 2022 Jul 19. doi: 10.1038/s41467-022-31408-y