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Select item 109360501.

Long noncoding RNA Gm2694 drives depressive-like behaviors in male mice by interacting with GRP78 to disrupt endoplasmic reticulum homeostasis

Hong-Sheng Chen, Ji Wang, Hou-Hong Li, Xiao Wang, Shao-Qi Zhang, Tan Deng, Yu-Ke Li, Ruo-Si Zou, Hua-Jie Wang, Rui Zhu, Wen-Long Xie, Gang Zhao, Fang Wang, Jian-Guo Chen

Sci Adv. 2022 Dec; 8(48): eabn2496. Published online 2022 Dec 2. doi: 10.1126/sciadv.abn2496

PMCID:: PMC10936050

Abstract Article PDF–7.2M

Select item 109176602.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 107877913.

Loss of Mptx2 alters bacteria composition and intestinal homeostasis potentially by impairing autophagy

Weihui Yan, Shanshan Chen, Ying Wang, Yaying You, Ying Lu, Weipeng Wang, Bo Wu, Jun Du, Shicheng Peng, Wei Cai, Yongtao Xiao

Commun Biol. 2024; 7: 94. Published online 2024 Jan 13. doi: 10.1038/s42003-024-05785-7

PMCID:: PMC10787791

Abstract Article PDF–21M

Select item 107554984.

Intestinal SURF4 is essential for apolipoprotein transport and lipoprotein secretion

Chun-Guang Guo, Rui Sun, Xiao Wang, Ye Yuan, Yan Xu, Shihan Li, Xueting Sun, Jue Wang, Xinli Hu, Tiannan Guo, Xiao-Wei Chen, Rui-Ping Xiao, Xiuqin Zhang

Mol Metab. 2024 Jan; 79: 101847. Published online 2023 Nov 30. doi: 10.1016/j.molmet.2023.101847

PMCID:: PMC10755498

Abstract Article PDF–3.6M

Select item 106702915.

ATF4 May Be Essential for Adaption of the Ocular Lens to Its Avascular Environment

Jiawen Xiang, Anthony J. Pompetti, Adam P. Faranda, Yan Wang, Samuel G. Novo, David Wan-Cheng Li, Melinda K. Duncan

Cells. 2023 Nov; 12(22): 2636. Published online 2023 Nov 16. doi: 10.3390/cells12222636

PMCID:: PMC10670291

Abstract Article PDF–9.2M

Select item 104659246.

Grp78 is required for intestinal Kras-dependent glycolysis proliferation and adenomagenesis

Claudia N Spaan, Ruben J de Boer, Wouter L Smit, Jonathan HM van der Meer, Manon van Roest, Jacqueline LM Vermeulen, Pim J Koelink, Marte AJ Becker, Simei Go, Joana Silva, William J Faller, Gijs R van den Brink, Vanesa Muncan, Jarom Heijmans

Life Sci Alliance. 2023 Nov; 6(11): e202301912. Published online 2023 Aug 29. doi: 10.26508/lsa.202301912

PMCID:: PMC10465924

Abstract Article PDF–1.9M

Select item 102944517.

Disturbance of neuron–microglia crosstalk mediated by GRP78 in Neuropsychiatric systemic lupus erythematosus mice

Jingyi Xu, Chunshu Yang, Siyuan Zeng, Xuejiao Wang, Pingting Yang, Ling Qin

J Neuroinflammation. 2023; 20: 150. Published online 2023 Jun 26. doi: 10.1186/s12974-023-02832-8

PMCID:: PMC10294451

Abstract Article PDF–7.5M

Select item 102901028.

NFIC regulates ribosomal biology and ER stress in pancreatic acinar cells and restrains PDAC initiation

Isidoro Cobo, Sumit Paliwal, Cristina Bodas, Irene Felipe, Júlia Melià-Alomà, Ariadna Torres, Jaime Martínez-Villarreal, Marina Malumbres, Fernando García, Irene Millán, Natalia del Pozo, Joo-Cheol Park, Ray J. MacDonald, Javier Muñoz, Raúl Méndez, Francisco X. Real

Nat Commun. 2023; 14: 3761. Published online 2023 Jun 23. doi: 10.1038/s41467-023-39291-x

PMCID:: PMC10290102

Abstract Article PDF–3.4M

Select item 101906079.

The inhibition of ORMDL3 prevents Alzheimer's disease through ferroptosis by PERK/ATF4/HSPA5 pathway

Yankun Shao, Yilin Xu, Huang Di, Xinxiu Shi, Yingying Wang, Hongyu Liu, Lina Song

IET Nanobiotechnol. 2023 May; 17(3): 182–196. Published online 2023 Jan 20. doi: 10.1049/nbt2.12113

PMCID:: PMC10190607

Abstract Article PDF–4.2M

Select item 1004632510.

Immunoexpression Pattern of Autophagy Markers in Developing and Postnatal Kidneys of Dab1^−/−(yotari) Mice

Mirko Maglica, Nela Kelam, Ejazul Haque, Ilija Perutina, Anita Racetin, Natalija Filipović, Yu Katsuyama, Katarina Vukojević

Biomolecules. 2023 Mar; 13(3): 402. Published online 2023 Feb 21. doi: 10.3390/biom13030402

PMCID:: PMC10046325

Abstract Article PDF–72M

Select item 984843111.

The effects of 4-Phenylbutyric acid on ER stress during mouse tooth development

Eui-Seon Lee, Yam Prasad Aryal, Tae-Young Kim, Elina Pokharel, Ji-Youn Kim, Hitoshi Yamamoto, Chang-Hyeon An, Seo-Young An, Jae-Kwang Jung, Youngkyun Lee, Jung-Hong Ha, Wern-Joo Sohn, Jae-Young Kim

Front Physiol. 2022; 13: 1079355. Published online 2023 Jan 4. doi: 10.3389/fphys.2022.1079355

PMCID:: PMC9848431

Abstract Article PDF–4.4M

Select item 976094812.

Citrullinated glucose-regulated protein 78 is a candidate target for melanoma immunotherapy

Victoria Anne Brentville, Peter Symonds, JiaXin Chua, Anne Skinner, Ian Daniels, Katherine Wendy Cook, Sasa Koncarevic, Roxana Martinez-Pinna, Sabaria Shah, Ruhul Hasan Choudhury, Poonam Vaghela, Daisy Weston, Abdullah Al-Omari, James Davis, Lindy G. Durrant

Front Immunol. 2022; 13: 1066185. Published online 2022 Dec 5. doi: 10.3389/fimmu.2022.1066185

PMCID:: PMC9760948

Abstract Article PDF–2.4M

Select item 974691613.

HIF1 inhibitor acriflavine rescues early-onset preeclampsia phenotype in mice lacking placental prolyl hydroxylase domain protein 2

Julien Sallais, Chanho Park, Sruthi Alahari, Tyler Porter, Ruizhe Liu, Merve Kurt, Abby Farrell, Martin Post, Isabella Caniggia

JCI Insight. 2022 Dec 8; 7(23): e158908. Published online 2022 Dec 8. doi: 10.1172/jci.insight.158908

PMCID:: PMC9746916

Abstract Article PDF–7.1M

Select item 960672214.

O-fucosylation of thrombospondin type 1 repeats is essential for ECM remodeling and signaling during bone development

Sanjiv Neupane, Steven J. Berardinelli, Daniel C. Cameron, Richard C. Grady, David E. Komatsu, Christopher J. Percival, Megumi Takeuchi, Atsuko Ito, Ta-Wei Liu, Alison V. Nairn, Kelley W. Moremen, Robert S. Haltiwanger, Bernadette C. Holdener

Matrix Biol. Author manuscript; available in PMC 2022 Oct 27.

Published in final edited form as: Matrix Biol. 2022 Mar; 107: 77–96. Published online 2022 Feb 12. doi: 10.1016/j.matbio.2022.02.002

PMCID:: PMC9606722

Abstract Article PDF–6.7M

Select item 960386015.

The Deubiquitinating Enzyme USP48 Interacts with the Retinal Degeneration-Associated Proteins UNC119a and ARL3

Laura Sánchez-Bellver, Andrea Férriz-Gordillo, Marc Carrillo-Pz, Laura Rabanal, Francesc R. Garcia-Gonzalo, Gemma Marfany

Int J Mol Sci. 2022 Oct; 23(20): 12527. Published online 2022 Oct 19. doi: 10.3390/ijms232012527

PMCID:: PMC9603860

Abstract Article PDF–3.4M

Select item 955156716.

KRAS protein expression becomes progressively restricted during embryogenesis and in adulthood

Marie-Albane Minati, Mohamad Assi, Maxime Libert, Sabine Cordi, Frédéric Lemaigre, Patrick Jacquemin

Front Cell Dev Biol. 2022; 10: 995013. Published online 2022 Sep 27. doi: 10.3389/fcell.2022.995013

PMCID:: PMC9551567

Abstract Article PDF–5.6M

Select item 944061117.

Deficiency of Jamc Leads to Congenital Nuclear Cataract and Activates the Unfolded Protein Response in Mouse Lenses

Jiani Li, Xuhua Tan, Qihang Sun, Xuri Li, Rongyuan Chen, Lixia Luo

Invest Ophthalmol Vis Sci. 2022 Sep; 63(10): 1. Published online 2022 Sep 1. doi: 10.1167/iovs.63.10.1

PMCID:: PMC9440611

Abstract Article PDF–10M

Select item 938238918.

Paternal obesity induces placental hypoxia and sex-specific impairments in placental vascularization and offspring metabolism

Patrycja A Jazwiec, Violet S Patterson, Tatiane A Ribeiro, Erica Yeo, Katherine M Kennedy, Paulo C F Mathias, Jim J Petrik, Deborah M Sloboda

Biol Reprod. 2022 Aug; 107(2): 574–589. Published online 2022 Apr 4. doi: 10.1093/biolre/ioac066

PMCID:: PMC9382389

Abstract Article PDF–1.7M

Select item 925058919.

Disruption of Trip11 in cranial neural crest cells is associated with increased ER and Golgi stress contributing to skull defects in mice

Hiroyuki Yamaguchi, Matthew D. Meyer, Li He, Yoshihiro Komatsu

Dev Dyn. Author manuscript; available in PMC 2023 Jul 1.

Published in final edited form as: Dev Dyn. 2022 Jul; 251(7): 1209–1222. Published online 2022 Feb 18. doi: 10.1002/dvdy.461

PMCID:: PMC9250589

Abstract Article PDF–2.3M

Select item 885027520.

Neutrophils Contribute to ER Stress in Lung Epithelial Cells in the Pristane-Induced Diffuse Alveolar Hemorrhage Mouse Model

Gantsetseg Tumurkhuu, Duygu Ercan Laguna, Richard E. Moore, Jorge Contreras, Gabriela De Los Santos, Luisa Akaveka, Erica N. Montano, Yizhou Wang, Mariko Ishimori, Swamy Venuturupalli, Lindsy J. Forbess, Barry R. Stripp, Daniel J. Wallace, Caroline A. Jefferies

Front Immunol. 2022; 13: 790043. Published online 2022 Feb 3. doi: 10.3389/fimmu.2022.790043

PMCID:: PMC8850275

Abstract Article PDF–3.3M

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