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Select item 109444581.

Axl and MerTK regulate synovial inflammation and are modulated by IL-6 inhibition in rheumatoid arthritis

Alessandra Nerviani, Marie-Astrid Boutet, Giulia Maria Ghirardi, Katriona Goldmann, Elisabetta Sciacca, Felice Rivellese, Elena Pontarini, Edoardo Prediletto, Federico Abatecola, Mattia Caliste, Sara Pagani, Daniele Mauro, Mattia Bellan, Cankut Cubuk, Rachel Lau, Sarah E. Church, Briana M. Hudson, Frances Humby, Michele Bombardieri, Myles J. Lewis, Costantino Pitzalis

Nat Commun. 2024; 15: 2398. Published online 2024 Mar 16. doi: 10.1038/s41467-024-46564-6

PMCID:: PMC10944458

Abstract Article PDF–5.4M

Select item 108869202.

Signaling Pathways of AXL Receptor Tyrosine Kinase Contribute to the Pathogenetic Mechanisms of Glioblastoma

Alberto Repici, Alessio Ardizzone, Fabiola De Luca, Lorenzo Colarossi, Angela Prestifilippo, Gabriele Pizzino, Irene Paterniti, Emanuela Esposito, Anna Paola Capra

Cells. 2024 Feb; 13(4): 361. Published online 2024 Feb 19. doi: 10.3390/cells13040361

PMCID:: PMC10886920

Abstract Article PDF–1.1M

Select item 105688773.

AXL receptor tyrosine kinase modulates gonadotropin-releasing hormone receptor signaling

Pardis Mohammadzadeh, Mina Roueinfar, Gregory C. Amberg

Cell Commun Signal. 2023; 21: 284. Published online 2023 Oct 12. doi: 10.1186/s12964-023-01313-y

PMCID:: PMC10568877

Abstract Article PDF–3.3M

Select item 103109214.

AXL/Gas6 signaling mechanisms in the hypothalamic-pituitary-gonadal axis

Pardis Mohammadzadeh, Gregory C. Amberg

Front Endocrinol (Lausanne) 2023; 14: 1212104. Published online 2023 Jun 15. doi: 10.3389/fendo.2023.1212104

PMCID:: PMC10310921

Abstract Article PDF–1.0M

Select item 102736965.

AXL in cancer: a modulator of drug resistance and therapeutic target

Yaoxiang Tang, Hongjing Zang, Qiuyuan Wen, Songqing Fan

J Exp Clin Cancer Res. 2023; 42: 148. Published online 2023 Jun 16. doi: 10.1186/s13046-023-02726-w

PMCID:: PMC10273696

Abstract Article PDF–2.1M

Select item 102374226.

TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan

Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233

PMCID:: PMC10237422

Abstract Article PDF–23M

Select item 101263067.

Identifying key genes related to inflammasome in severe COVID-19 patients based on a joint model with random forest and artificial neural network

Haiya Ou, Yaohua Fan, Xiaoxuan Guo, Zizhao Lao, Meiling Zhu, Geng Li, Lijun Zhao

Front Cell Infect Microbiol. 2023; 13: 1139998. Published online 2023 Apr 11. doi: 10.3389/fcimb.2023.1139998

PMCID:: PMC10126306

Abstract Article PDF–12M

Select item 100729068.

Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity

Martin Golkowski, Andrea Lius, Tanmay Sapre, Ho-Tak Lau, Taylor Moreno, Dustin J. Maly, Shao-En Ong

Mol Cell. Author manuscript; available in PMC 2023 Apr 4.

Published in final edited form as: Mol Cell. 2023 Mar 2; 83(5): 803–818.e8. Published online 2023 Feb 2. doi: 10.1016/j.molcel.2023.01.015

PMCID:: PMC10072906

Abstract Article PDF–4.2M

Select item 100577409.

Axl contributes to efficient migration and invasion of melanoma cells

Hanshuang Shao, Diana Teramae, Alan Wells

PLoS One. 2023; 18(3): e0283749. Published online 2023 Mar 29. doi: 10.1371/journal.pone.0283749

PMCID:: PMC10057740

Abstract Article PDF–1.7M

Select item 989960310.

High levels of AXL expression in untreated EGFR‐mutated non‐small cell lung cancer negatively impacts the use of osimertinib

Akihiro Yoshimura, Tadaaki Yamada, Masakuni Serizawa, Hisanori Uehara, Keiko Tanimura, Yusuke Okuma, Akito Fukuda, Satoshi Watanabe, Naoya Nishioka, Takayuki Takeda, Yusuke Chihara, Shinnosuke Takemoto, Taishi Harada, Osamu Hiranuma, Yukina Shirai, Takehito Shukuya, Akihiro Nishiyama, Yasuhiro Goto, Shinsuke Shiotsu, Kei Kunimasa, Kenji Morimoto, Yuki Katayama, Kenichi Suda, Tetsuya Mitsudomi, Seiji Yano, Hirotsugu Kenmotsu, Toshiaki Takahashi, Koichi Takayama

Cancer Sci. 2023 Feb; 114(2): 606–618. Published online 2022 Nov 11. doi: 10.1111/cas.15608

PMCID:: PMC9899603

Abstract Article PDF–1.8M

Select item 983366911.

Identification of AXL as a co-receptor for human parvovirus B19 infection of human erythroid progenitors

Kang Ning, Wei Zou, Peng Xu, Fang Cheng, Elizabeth Yan Zhang, Aaron Zhang-Chen, Steve Kleiboeker, Jianming Qiu

Sci Adv. 2023 Jan; 9(2): eade0869. Published online 2023 Jan 11. doi: 10.1126/sciadv.ade0869

PMCID:: PMC9833669

Abstract Article PDF–1.5M

Select item 968805712.

Decreased CSTB, RAGE, and Axl Receptor Are Associated with Zika Infection in the Human Placenta

Gabriel Borges-Vélez, Juan A. Arroyo, Yadira M. Cantres-Rosario, Ana Rodriguez de Jesus, Abiel Roche-Lima, Julio Rosado-Philippi, Lester J. Rosario-Rodríguez, María S. Correa-Rivas, Maribel Campos-Rivera, Loyda M. Meléndez

Cells. 2022 Nov; 11(22): 3627. Published online 2022 Nov 16. doi: 10.3390/cells11223627

PMCID:: PMC9688057

Abstract Article PDF–5.5M

Select item 953588313.

AXL, along with PROS1, is overexpressed in papillary thyroid carcinoma and regulates its biological behaviour

Mingze Wei, Yizeng Wang, Yuanchao Liu, Dongyang Li, Xianghui He

World J Surg Oncol. 2022; 20: 334. Published online 2022 Oct 6. doi: 10.1186/s12957-022-02801-0

PMCID:: PMC9535883

Abstract Article PDF–1.6M

Select item 946247614.

Axon guidance receptor ROBO3 modulates subtype identity and prognosis via AXL-associated inflammatory network in pancreatic cancer

Niklas Krebs, Lukas Klein, Florian Wegwitz, Elisa Espinet, Hans Carlo Maurer, Mengyu Tu, Frederike Penz, Stefan Küffer, Xingbo Xu, Hanibal Bohnenberger, Silke Cameron, Marius Brunner, Albrecht Neesse, Uday Kishore, Elisabeth Hessmann, Andreas Trumpp, Philipp Ströbel, Rolf A. Brekken, Volker Ellenrieder, Shiv K. Singh

JCI Insight. 2022 Aug 22; 7(16): e154475. Published online 2022 Aug 22. doi: 10.1172/jci.insight.154475

PMCID:: PMC9462476

Abstract Article PDF–6.0M

Select item 929877815.

Increased serum AXL is associated with radiographic knee osteoarthritis severity

Shao Zhenghai

Int J Rheum Dis. 2022 Jan; 25(1): 32–37. Published online 2021 Nov 28. doi: 10.1111/1756-185X.14239

PMCID:: PMC9298778

Abstract Article PDF–683K

Select item 926436316.

Mitochondrial antiviral-signalling protein is a client of the BAG6 protein quality control complex

Peristera Roboti, Craig Lawless, Stephen High

J Cell Sci. 2022 May 1; 135(9): jcs259596. Published online 2022 May 11. doi: 10.1242/jcs.259596

PMCID:: PMC9264363

Abstract Article

Select item 923162317.

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1

Boris Simonetti, James L. Daly, Lorena Simón-Gracia, Katja Klein, Saroja Weeratunga, Carlos Antón-Plágaro, Allan Tobi, Lorna Hodgson, Philip A. Lewis, Kate J. Heesom, Deborah K. Shoemark, Andrew D. Davidson, Brett M. Collins, Tambet Teesalu, Yohei Yamauchi, Peter J. Cullen

Proc Natl Acad Sci U S A. 2022 Jun 21; 119(25): e2201980119. Published online 2022 Jun 13. doi: 10.1073/pnas.2201980119

PMCID:: PMC9231623

Abstract Article PDF–6.0M

Select item 917141118.

Physical and functional interactome atlas of human receptor tyrosine kinases

Kari Salokas, Xiaonan Liu, Tiina Öhman, Iftekhar Chowdhury, Lisa Gawriyski, Salla Keskitalo, Markku Varjosalo

EMBO Rep. 2022 Jun; 23(6): e54041. Published online 2022 Apr 5. doi: 10.15252/embr.202154041

PMCID:: PMC9171411

Abstract Article PDF–1.9M

Select item 913559719.

Endocytic trafficking of GAS6–AXL complexes is associated with sustained AKT activation

Agata Poświata, Kamila Kozik, Marta Miączyńska, Daria Zdżalik-Bielecka

Cell Mol Life Sci. 2022 Jun; 79(6): 316. Published online 2022 May 27. doi: 10.1007/s00018-022-04312-3

PMCID:: PMC9135597

Abstract Article PDF–10M

Select item 912574720.

Growth Arrest Specific-6 and Axl Coordinate Inflammation and Hypertension

Justin P. Van Beusecum, Natalia R. Barbaro, Charles D. Smart, David M. Patrick, Roxana Loperena, Shilin Zhao, Mingfang Ao, Liang Xiao, Cyndya A. Shibao, David G. Harrison

Circ Res. Author manuscript; available in PMC 2022 Nov 12.

Published in final edited form as: Circ Res. 2021 Nov 12; 129(11): 975–991. Published online 2021 Sep 27. doi: 10.1161/CIRCRESAHA.121.319643

PMCID:: PMC9125747

Abstract Article PDF–2.4M

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