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Select item 111138421.

Apaf1-deficient cortical neurons exhibit defects in axonal outgrowth

Daniela De Zio, Francesca Molinari, Salvatore Rizza, Lucia Gatta, Maria Teresa Ciotti, Anna Maria Salvatore, Søs Grønbæk Mathiassen, Andrzej W. Cwetsch, Giuseppe Filomeni, Giuseppe Rosano, Elisabetta Ferraro

Cell Mol Life Sci. 2015 Nov; 72(21): 4173–4191. Published online 2015 May 15. doi: 10.1007/s00018-015-1927-x

PMCID:: PMC11113842

Abstract Article PDF–1.8M

Select item 110430752.

Functional synergy of a human-specific and an ape-specific metabolic regulator in human neocortex development

Lei Xing, Vasiliki Gkini, Anni I. Nieminen, Hui-Chao Zhou, Matilde Aquilino, Ronald Naumann, Katrin Reppe, Kohichi Tanaka, Peter Carmeliet, Oskari Heikinheimo, Svante Pääbo, Wieland B. Huttner, Takashi Namba

Nat Commun. 2024; 15: 3468. Published online 2024 Apr 24. doi: 10.1038/s41467-024-47437-8

PMCID:: PMC11043075

Abstract Article PDF–1.8M

Select item 110146573.

A BMP-controlled metabolic/epigenetic signaling cascade directs midfacial morphogenesis

Jingwen Yang, Lingxin Zhu, Haichun Pan, Hiroki Ueharu, Masako Toda, Qian Yang, Shawn A. Hallett, Lorin E. Olson, Yuji Mishina

J Clin Invest. 2024 Apr 15; 134(8): e165787. Published online 2024 Mar 11. doi: 10.1172/JCI165787

PMCID:: PMC11014657

Abstract Article PDF–16M

Select item 109176604.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 107171345.

EAE-induced upregulation of mitochondrial MnSOD is associated with increases of mitochondrial SGK1 and Tom20 protein in the mouse kidney cortex

Sharanpreet Hira, Balamuguran Packialakshmi, Xiaoming Zhou

J Physiol Sci. 2019 Sep; 69(5): 723–732. Published online 2019 Jun 8. doi: 10.1007/s12576-019-00687-4

PMCID:: PMC10717134

Abstract Article PDF–821K

Select item 105896736.

Impairment of serine transport across the blood–brain barrier by deletion of Slc38a5 causes developmental delay and motor dysfunction

Inna Radzishevsky, Maali Odeh, Oded Bodner, Salman Zubedat, Lihi Shaulov, Maxim Litvak, Kayoko Esaki, Takeo Yoshikawa, Bella Agranovich, Wen-Hong Li, Alex Radzishevsky, Eyal Gottlieb, Avi Avital, Herman Wolosker

Proc Natl Acad Sci U S A. 2023 Oct 17; 120(42): e2302780120. Published online 2023 Oct 9. doi: 10.1073/pnas.2302780120

PMCID:: PMC10589673

Abstract Article PDF–6.8M

Select item 104616057.

Monitoring mitochondrial calcium and metabolism in the beating MCU-KO heart

A Kosmach, B Roman, J Sun, A Femnou, F Zhang, C Liu, CA Combs, RS Balaban, E Murphy

Cell Rep. Author manuscript; available in PMC 2023 Aug 28.

Published in final edited form as: Cell Rep. 2021 Oct 19; 37(3): 109846. doi: 10.1016/j.celrep.2021.109846

PMCID:: PMC10461605

Abstract Article PDF–1.6M

Select item 103626438.

Iron induces B cell pyroptosis through Tom20–Bax–caspase–gasdermin E signaling to promote inflammation post-spinal cord injury

Chengjie Wu, Lining Wang, Sixian Chen, Lei Shi, Mengmin Liu, Pengcheng Tu, Jie Sun, Ruihua Zhao, Yafeng Zhang, Jianwei Wang, Yalan Pan, Yong Ma, Yang Guo

J Neuroinflammation. 2023; 20: 171. Published online 2023 Jul 22. doi: 10.1186/s12974-023-02848-0

PMCID:: PMC10362643

Abstract Article PDF–17M

Select item 100105629.

The RNA binding protein DND1 is elevated in a subpopulation of pro-spermatogonia and targets chromatin modifiers and translational machinery during late gestation

Victor A. Ruthig, Talia Hatkevich, Josiah Hardy, Matthew B. Friedersdorf, Chloé Mayère, Serge Nef, Jack D. Keene, Blanche Capel

PLoS Genet. 2023 Mar; 19(3): e1010656. Published online 2023 Mar 1. doi: 10.1371/journal.pgen.1010656

PMCID:: PMC10010562

Abstract Article PDF–2.8M

Select item 944061110.

Deficiency of Jamc Leads to Congenital Nuclear Cataract and Activates the Unfolded Protein Response in Mouse Lenses

Jiani Li, Xuhua Tan, Qihang Sun, Xuri Li, Rongyuan Chen, Lixia Luo

Invest Ophthalmol Vis Sci. 2022 Sep; 63(10): 1. Published online 2022 Sep 1. doi: 10.1167/iovs.63.10.1

PMCID:: PMC9440611

Abstract Article PDF–10M

Select item 943472411.

Ambra1 deficiency impairs mitophagy in skeletal muscle

Lisa Gambarotto, Samuele Metti, Martina Chrisam, Cristina Cerqua, Patrizia Sabatelli, Andrea Armani, Carlo Zanon, Marianna Spizzotin, Silvia Castagnaro, Flavie Strappazzon, Paolo Grumati, Matilde Cescon, Paola Braghetta, Eva Trevisson, Francesco Cecconi, Paolo Bonaldo

J Cachexia Sarcopenia Muscle. 2022 Aug; 13(4): 2211–2224. Published online 2022 May 20. doi: 10.1002/jcsm.13010

PMCID:: PMC9434724

Abstract Article PDF–9.7M

Select item 925823112.

Neuropathy-associated Fars2 deficiency affects neuronal development and potentiates neuronal apoptosis by impairing mitochondrial function

Xihui Chen, Fangfang Liu, Bowen Li, Yufeng Wang, Lijuan Yuan, Anan Yin, Qi Chen, Weihong Hu, Yan Yao, Mengjie Zhang, YuanMing Wu, Kun Chen

Cell Biosci. 2022; 12: 103. Published online 2022 Jul 6. doi: 10.1186/s13578-022-00838-y

PMCID:: PMC9258231

Abstract Article PDF–12M

Select item 891933313.

Drp1 regulates transcription of ribosomal protein genes in embryonic hearts

Qiancong Zhao, Shun Yan, Jin Lu, Danitra J. Parker, Huiying Wu, Qianchuang Sun, David K. Crossman, Shanrun Liu, Qin Wang, Hiromi Sesaki, Kasturi Mitra, Kexiang Liu, Kai Jiao

J Cell Sci. 2022 Feb 15; 135(4): jcs258956. Published online 2022 Feb 21. doi: 10.1242/jcs.258956

PMCID:: PMC8919333

Abstract Article

Select item 831323914.

Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development

Francesco Bedogni, Robert F. Hevner

Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034

PMCID:: PMC8313239

Abstract Article PDF–1.6M

Select item 754976815.

Deficiency of the Tbc1d21 gene causes male infertility with morphological abnormalities of the sperm mitochondria and flagellum in mice

Ya-Yun Wang, Chih-Chun Ke, Yen-Lin Chen, Yu-Hua Lin, I-Shing Yu, Wei-Chi Ku, Moira K. O’Bryan, Ying-Hung Lin

PLoS Genet. 2020 Sep; 16(9): e1009020. Published online 2020 Sep 25. doi: 10.1371/journal.pgen.1009020

PMCID:: PMC7549768

Abstract Article PDF–2.9M

Select item 741599116.

BioID screening of biotinylation sites using the avidin-like protein Tamavidin 2-REV identifies global interactors of stimulator of interferon genes (STING)

Kou Motani, Hidetaka Kosako

J Biol Chem. 2020 Aug 7; 295(32): 11174–11183. Published online 2020 Jun 17. doi: 10.1074/jbc.RA120.014323

PMCID:: PMC7415991

Abstract Article PDF–2.0M

Select item 727233417.

Nuclear-encoded mitochondrial ribosomal proteins are required to initiate gastrulation

Agnes Cheong, Danielle Archambault, Rinat Degani, Elizabeth Iverson, Kimberly D. Tremblay, Jesse Mager

Development. 2020 May 15; 147(10): dev188714. Published online 2020 May 26. doi: 10.1242/dev.188714

PMCID:: PMC7272334

Abstract Article

Select item 634761918.

Beclin 1 regulates recycling endosome and is required for skin development in mice

Saori Noguchi, Shinya Honda, Tatsuya Saitoh, Hiroyuki Matsumura, Emi Nishimura, Shizuo Akira, Shigeomi Shimizu

Commun Biol. 2019; 2: 37. Published online 2019 Jan 25. doi: 10.1038/s42003-018-0279-0

PMCID:: PMC6347619

Abstract Article PDF–4.1M

Select item 633677719.

Tip60- and sirtuin 2-regulated MARCKS acetylation and phosphorylation are required for diabetic embryopathy

Penghua Yang, Cheng Xu, E. Albert Reece, Xi Chen, Jianxiang Zhong, Min Zhan, Deborah J. Stumpo, Perry J. Blackshear, Peixin Yang

Nat Commun. 2019; 10: 282. Published online 2019 Jan 17. doi: 10.1038/s41467-018-08268-6

PMCID:: PMC6336777

Abstract Article PDF–6.8M

Select item 633346020.

ATG5 is required for B cell polarization and presentation of particulate antigens

Florent Arbogast, Johan Arnold, Philippe Hammann, Lauriane Kuhn, Johana Chicher, Diane Murera, Justine Weishaar, Sylviane Muller, Jean-Daniel Fauny, Frédéric Gros

Autophagy. 2019; 15(2): 280–294. Published online 2018 Sep 22. doi: 10.1080/15548627.2018.1516327

PMCID:: PMC6333460

Abstract Article PDF–2.7M

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