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Items: 1 to 20 of 30

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
FAP-targeted CAR-T suppresses MDSCs recruitment to improve the antitumor efficacy of claudin18.2-targeted CAR-T against pancreatic cancer
Yifan Liu, Yansha Sun, Peng Wang, Songling Li, Yiwei Dong, Min Zhou, Bizhi Shi, Hua Jiang, Ruixin Sun, Zonghai Li
J Transl Med. 2023; 21: 255. Published online 2023 Apr 12. doi: 10.1186/s12967-023-04080-z
PMCID:
PMC10091631
AbstractArticlePDF–10M
3.
Claudin-9 constitutes tight junctions of folliculo-stellate cells in the anterior pituitary gland
Atsuko Y. Higashi, Tomohito Higashi, Kyoko Furuse, Kana Ozeki, Mikio Furuse, Hideki Chiba
Sci Rep. 2021; 11: 21642. Published online 2021 Nov 4. doi: 10.1038/s41598-021-01004-z
PMCID:
PMC8568902
AbstractArticlePDF–7.0M
4.
Deficiency of lung-specific claudin-18 leads to aggravated infection with Cryptococcus deneoformans through dysregulation of the microenvironment in lungs
Ko Sato, Ikumi Matsumoto, Koya Suzuki, Atsushi Tamura, Aki Shiraishi, Hiroshi Kiyonari, Jun Kasamatsu, Hideki Yamamoto, Tomomitsu Miyasaka, Daiki Tanno, Anna Miyahara, Tong Zong, Takafumi Kagesawa, Akiho Oniyama, Kotone Kawamura, Yuki Kitai, Aya Umeki, Emi Kanno, Hiromasa Tanno, Keiko Ishii, Sachiko Tsukita, Kazuyoshi Kawakami
Sci Rep. 2021; 11: 21110. Published online 2021 Oct 26. doi: 10.1038/s41598-021-00708-6
PMCID:
PMC8548597
AbstractArticlePDF–2.3M
5.
Claudin-18 Loss Alters Transcellular Chloride Flux but not Tight Junction Ion Selectivity in Gastric Epithelial Cells
Tyler J. Caron, Kathleen E. Scott, Nishita Sinha, Sureshkumar Muthupalani, Mahnoor Baqai, Lay-Hong Ang, Yue Li, Jerrold R. Turner, James G. Fox, Susan J. Hagen
Cell Mol Gastroenterol Hepatol. 2021; 11(3): 783–801. Published online 2020 Oct 16. doi: 10.1016/j.jcmgh.2020.10.005
PMCID:
PMC7847960
AbstractArticlePDF–7.5M
6.
Epithelial expression of Gata4 and Sox2 regulates specification of the squamous–columnar junction via MAPK/ERK signaling in mice
Nao Sankoda, Wataru Tanabe, Akito Tanaka, Hirofumi Shibata, Knut Woltjen, Tsutomu Chiba, Hironori Haga, Yoshiharu Sakai, Masaki Mandai, Takuya Yamamoto, Yasuhiro Yamada, Shinji Uemoto, Yoshiya Kawaguchi
Nat Commun. 2021; 12: 560. Published online 2021 Jan 25. doi: 10.1038/s41467-021-20906-0
PMCID:
PMC7835245
AbstractArticlePDF–16M
7.
Loss of Tight Junction Protein Claudin-18 Promotes Rapid Cancer Development in Mouse Stomach
Susan J. Hagen, Lay-Hong Ang, Yi Zheng, Salih N. Karahan, Jessica Wu, Yaoyu E. Wang, Tyler Caron, Aniket Gad, Sureshkumar Muthupalani, James G. Fox
Gastroenterology. Author manuscript; available in PMC 2019 Jul 8.
Published in final edited form as: Gastroenterology. 2018 Dec; 155(6): 1852–1867. Published online 2018 Sep 7. doi: 10.1053/j.gastro.2018.08.041
PMCID:
PMC6613545
AbstractArticlePDF–2.4M
8.
Deficiency of Stomach-Type Claudin-18 in Mice Induces Gastric Tumor Formation Independent of H pylori Infection
Koya Suzuki, Kazuhiro Sentani, Hiroo Tanaka, Tomoki Yano, Kazuo Suzuki, Masanobu Oshima, Wataru Yasui, Atsushi Tamura, Sachiko Tsukita
Cell Mol Gastroenterol Hepatol. 2019; 8(1): 119–142. Published online 2019 Mar 23. doi: 10.1016/j.jcmgh.2019.03.003
PMCID:
PMC6554658
AbstractArticlePDF–15M
9.
Genetic ablation of carbonic anhydrase IX disrupts gastric barrier function via claudin‐18 downregulation and acid backflux
T. Li, X. Liu, B. Riederer, K. Nikolovska, A. K. Singh, K. A. Mäkelä, A. Seidler, Y. Liu, G. Gros, H. Bartels, K. H. Herzig, U. Seidler
Acta Physiol (Oxf) 2018 Apr; 222(4): e12923. Published online 2017 Oct 19. doi: 10.1111/apha.12923
PMCID:
PMC5901031
AbstractArticlePDF–2.4M
10.
Transitional basal cells at the squamous-columnar junction generate Barrett’s oesophagus
Ming Jiang, Haiyan Li, Yongchun Zhang, Ying Yang, Rong Lu, Kuancan Liu, Sijie Lin, Xiaopeng Lan, Haikun Wang, Han Wu, Jian Zhu, Zhongren Zhou, Jianming Xu, Dong-Kee Lee, Lanjing Zhang, Yuan-Cho Lee, Jingsong Yuan, Julian A. Abrams, Timothy G. Wang, Antonia R. Sepulveda, Qi Wu, Huaiyong Chen, Xin Sun, Junjun She, Xiaoxin Chen, Jianwen Que
Nature. Author manuscript; available in PMC 2018 Apr 12.
Published in final edited form as: Nature. 2017 Oct 26; 550(7677): 529–533. Published online 2017 Oct 12. doi: 10.1038/nature24269
PMCID:
PMC5831195
AbstractArticlePDF–4.1M
11.
Claudin-18–mediated YAP activity regulates lung stem and progenitor cell homeostasis and tumorigenesis
Beiyun Zhou, Per Flodby, Jiao Luo, Dan R. Castillo, Yixin Liu, Fa-Xing Yu, Alicia McConnell, Bino Varghese, Guanglei Li, Nyam-Osor Chimge, Mitsuhiro Sunohara, Michael N. Koss, Wafaa Elatre, Peter Conti, Janice M. Liebler, Chenchen Yang, Crystal N. Marconett, Ite A. Laird-Offringa, Parviz Minoo, Kunliang Guan, Barry R. Stripp, Edward D. Crandall, Zea Borok
J Clin Invest. 2018 Mar 1; 128(3): 970–984. Published online 2018 Feb 5. doi: 10.1172/JCI90429
PMCID:
PMC5824875
AbstractArticlePDF–13M
12.
High-throughput discovery of novel developmental phenotypes
Mary E. Dickinson, Ann M. Flenniken, Xiao Ji, Lydia Teboul, Michael D. Wong, Jacqueline K. White, Terrence F. Meehan, Wolfgang J. Weninger, Henrik Westerberg, Hibret Adissu, Candice N. Baker, Lynette Bower, James M. Brown, L. Brianna Caddle, Francesco Chiani, Dave Clary, James Cleak, Mark J. Daly, James M. Denegre, Brendan Doe, Mary E. Dolan, Sarah M. Edie, Helmut Fuchs, Valerie Gailus-Durner, Antonella Galli, Alessia Gambadoro, Juan Gallegos, Shiying Guo, Neil R. Horner, Chih-wei Hsu, Sara J. Johnson, Sowmya Kalaga, Lance C. Keith, Louise Lanoue, Thomas N. Lawson, Monkol Lek, Manuel Mark, Susan Marschall, Jeremy Mason, Melissa L. McElwee, Susan Newbigging, Lauryl M.J. Nutter, Kevin A. Peterson, Ramiro Ramirez-Solis, Douglas J. Rowland, Edward Ryder, Kaitlin E. Samocha, John R. Seavitt, Mohammed Selloum, Zsombor Szoke-Kovacs, Masaru Tamura, Amanda G Trainor, Ilinca Tudose, Shigeharu Wakana, Jonathan Warren, Olivia Wendling, David B. West, Leeyean Wong, Atsushi Yoshiki, The International Mouse Phenotyping Consortium, Daniel G. MacArthur, Glauco P. Tocchini-Valentini, Xiang Gao, Paul Flicek, Allan Bradley, William C. Skarnes, Monica J. Justice, Helen E. Parkinson, Mark Moore, Sara Wells, Robert E. Braun, Karen L. Svenson, Martin Hrabe de Angelis, Yann Herault, Tim Mohun, Ann-Marie Mallon, R. Mark Henkelman, Steve D.M. Brown, David J. Adams, K.C. Kent Lloyd, Colin McKerlie, Arthur L. Beaudet, Maja Bucan, Stephen A. Murray
Nature. Author manuscript; available in PMC 2017 Mar 14.
Published in final edited form as: Nature. 2016 Sep 22; 537(7621): 508–514. Published online 2016 Sep 14. doi: 10.1038/nature19356
Correction in:
Nature. 2017 Nov 16; 551(7680): 398.
PMCID:
PMC5295821
AbstractArticlePDF–3.0M
13.
Claudin-18 deficiency is associated with airway epithelial barrier dysfunction and asthma
Kelly Sweerus, Marrah Lachowicz-Scroggins, Erin Gordon, Michael LaFemina, Xiaozhu Huang, Mihir Parikh, Cindy Kanegai, John V. Fahy, James A. Frank
J Allergy Clin Immunol. Author manuscript; available in PMC 2018 Jan 1.
Published in final edited form as: J Allergy Clin Immunol. 2017 Jan; 139(1): 72–81.e1. Published online 2016 Apr 20. doi: 10.1016/j.jaci.2016.02.035
PMCID:
PMC5073041
AbstractArticlePDF–975K
14.
High-throughput screening of mouse gene knockouts identifies established and novel skeletal phenotypes
Robert Brommage, Jeff Liu, Gwenn M Hansen, Laura L Kirkpatrick, David G Potter, Arthur T Sands, Brian Zambrowicz, David R Powell, Peter Vogel
Bone Res. 2014; 2: 14034. Published online 2014 Oct 28. doi: 10.1038/boneres.2014.34
PMCID:
PMC4472125
AbstractArticlePDF–1.6M
15.
Claudin-18 Deficiency Results in Alveolar Barrier Dysfunction and Impaired Alveologenesis in Mice
Michael J. LaFemina, Katherine M. Sutherland, Trevor Bentley, Linda W. Gonzales, Lennell Allen, Cheryl J. Chapin, Deepti Rokkam, Kelly A. Sweerus, Leland G. Dobbs, Philip L. Ballard, James A. Frank
Am J Respir Cell Mol Biol. 2014 Oct; 51(4): 550–558. doi: 10.1165/rcmb.2013-0456OC
PMCID:
PMC4189483
AbstractArticlePDF–1.4M
16.
Knockout Mice Reveal Key Roles for Claudin 18 in Alveolar Barrier Properties and Fluid Homeostasis
Guanglei Li, Per Flodby, Jiao Luo, Hidenori Kage, Arnold Sipos, Danping Gao, Yanbin Ji, LaMonta L. Beard, Crystal N. Marconett, Lucas DeMaio, Yong Ho Kim, Kwang-Jin Kim, Ite A. Laird-Offringa, Parviz Minoo, Janice M. Liebler, Beiyun Zhou, Edward D. Crandall, Zea Borok
Am J Respir Cell Mol Biol. 2014 Aug; 51(2): 210–222. doi: 10.1165/rcmb.2013-0353OC
PMCID:
PMC4148039
AbstractArticlePDF–1.9M
17.
A high‐calcium diet failed to rescue an osteopenia phenotype in claudin‐18 knockout mice
Fatima Z. Alshbool, Catrina Alarcon, Jon Wergedal, Subburaman Mohan
Physiol Rep. 2014 Jan 1; 2(1): e00200. Published online 2014 Jan 13. doi: 10.1002/phy2.200
PMCID:
PMC3967683
AbstractArticlePDF–934K
18.
The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data
Gautier Koscielny, Gagarine Yaikhom, Vivek Iyer, Terrence F. Meehan, Hugh Morgan, Julian Atienza-Herrero, Andrew Blake, Chao-Kung Chen, Richard Easty, Armida Di Fenza, Tanja Fiegel, Mark Grifiths, Alan Horne, Natasha A. Karp, Natalja Kurbatova, Jeremy C. Mason, Peter Matthews, Darren J. Oakley, Asfand Qazi, Jack Regnart, Ahmad Retha, Luis A. Santos, Duncan J. Sneddon, Jonathan Warren, Henrik Westerberg, Robert J. Wilson, David G. Melvin, Damian Smedley, Steve D. M. Brown, Paul Flicek, William C. Skarnes, Ann-Marie Mallon, Helen Parkinson
Nucleic Acids Res. 2014 Jan 1; 42(Database issue): D802–D809. Published online 2013 Nov 3. doi: 10.1093/nar/gkt977
PMCID:
PMC3964955
AbstractArticlePDF–5.7M
19.
Disruption of claudin-18 diminishes ovariectomy-induced bone loss in mice
Ha-Young Kim, Catrina Alarcon, Sheila Pourteymour, Jon E. Wergedal, Subburaman Mohan
Am J Physiol Endocrinol Metab. 2013 Mar 1; 304(5): E531–E537. Published online 2013 Jan 8. doi: 10.1152/ajpendo.00408.2012
PMCID:
PMC3602660
AbstractArticle
20.
Scribble is required for normal epithelial cell–cell contacts and lumen morphogenesis in the mammalian lung
Laura L. Yates, Carsten Schnatwinkel, Lee Hazelwood, Lauren Chessum, Anju Paudyal, Helen Hilton, M. Rosario Romero, Jonathan Wilde, Debora Bogani, Jeremy Sanderson, Caroline Formstone, Jennifer N. Murdoch, Lee A. Niswander, Andy Greenfield, Charlotte H. Dean
Dev Biol. 2013 Jan 15; 373(2): 267–280. doi: 10.1016/j.ydbio.2012.11.012
PMCID:
PMC3549499
AbstractArticle

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