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Items: 1 to 20 of 26

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
Gut commensal bacteria enhance pathogenesis of a tumorigenic murine retrovirus
Jessica Spring, Aly A. Khan, Sophie Lara, Kelly O’Grady, Jessica Wilks, Sandeep Gurbuxani, Steven Erickson, Michael Fischbach, Amy Jacobson, Alexander Chervonsky, Tatyana Golovkina
Cell Rep. Author manuscript; available in PMC 2023 May 29.
Published in final edited form as: Cell Rep. 2022 Sep 13; 40(11): 111341. doi: 10.1016/j.celrep.2022.111341
PMCID:
PMC10226680
AbstractArticlePDF–1.1M
3.
Hypoxia Induces M2 Macrophages to Express VSIG4 and Mediate Cardiac Fibrosis After Myocardial Infarction
Yan Wang, Yu Zhang, Jiao Li, Chaofu Li, Ranzun Zhao, Changyin Shen, Weiwei Liu, Jidong Rong, Zhenglong Wang, Junbo Ge, Bei Shi
Theranostics. 2023; 13(7): 2192–2209. Published online 2023 Apr 2. doi: 10.7150/thno.78736
PMCID:
PMC10157727
AbstractArticlePDF–12M
4.
In situ expansion and reprogramming of Kupffer cells elicit potent tumoricidal immunity against liver metastasis
Wei Liu, Xia Zhou, Qi Yao, Chen Chen, Qing Zhang, Keshuo Ding, Lu Li, Zhutian Zeng
J Clin Invest. 2023 Apr 17; 133(8): e157937. Published online 2023 Apr 17. doi: 10.1172/JCI157937
PMCID:
PMC10104906
AbstractArticlePDF–21M
5.
Gut microbial DNA and immune checkpoint gene Vsig4/CRIg are key antagonistic players in healthy aging and age-associated development of hypertension and diabetes
Matthew A. Liu, Shandy Shahabi, Suborno Jati, Kechun Tang, Hong Gao, Zhongmou Jin, Wyatt Miller, Frédéric A. Meunier, Wei Ying, Geert van den Bogaart, Gourisankar Ghosh, Sushil K. Mahata
Front Endocrinol (Lausanne) 2022; 13: 1037465. Published online 2022 Nov 11. doi: 10.3389/fendo.2022.1037465
PMCID:
PMC9691654
AbstractArticlePDF–19M
6.
Functional vulnerability of liver macrophages to capsules defines virulence of blood-borne bacteria
Haoran An, Chenyun Qian, Yijia Huang, Jing Li, Xianbin Tian, Jiaying Feng, Jiao Hu, Yujie Fang, Fangfang Jiao, Yuna Zeng, Xueting Huang, Xianbin Meng, Xue Liu, Xin Lin, Zhutian Zeng, Martin Guilliams, Alain Beschin, Yongwen Chen, Yuzhang Wu, Jing Wang, Marco Rinaldo Oggioni, John Leong, Jan-Willem Veening, Haiteng Deng, Rong Zhang, Hui Wang, Jiang Wu, Yan Cui, Jing-Ren Zhang
J Exp Med. 2022 Apr 4; 219(4): e20212032. Published online 2022 Mar 8. doi: 10.1084/jem.20212032
PMCID:
PMC8908791
AbstractArticlePDF–8.0M
7.
CRIg on liver macrophages clears pathobionts and protects against alcoholic liver disease
Yi Duan, Huikuan Chu, Katharina Brandl, Lu Jiang, Suling Zeng, Nairika Meshgin, Eleni Papachristoforou, Josepmaria Argemi, Beatriz G. Mendes, Yanhan Wang, Hua Su, Weizhong Sun, Cristina Llorente, Tim Hendrikx, Xiao Liu, Mojgan Hosseini, Tatiana Kisseleva, David A. Brenner, Ramon Bataller, Prakash Ramachandran, Michael Karin, Wenxian Fu, Bernd Schnabl
Nat Commun. 2021; 12: 7172. Published online 2021 Dec 9. doi: 10.1038/s41467-021-27385-3
PMCID:
PMC8660815
AbstractArticlePDF–2.5M
8.
VSIG4(+) peritoneal macrophages induce apoptosis of double-positive thymocyte via the secretion of TNF-α in a CLP-induced sepsis model resulting in thymic atrophy
Hae-Yun Cho, Yun Gyeong Yang, Youkyoung Jeon, Chae-Kwan Lee, InHak Choi, Soo-Woong Lee
Cell Death Dis. 2021 Jun; 12(6): 526. Published online 2021 May 22. doi: 10.1038/s41419-021-03806-5
PMCID:
PMC8139869
AbstractArticlePDF–4.0M
9.
Immune checkpoint protein VSIG4 as a biomarker of aging in murine adipose tissue
Brandon M. Hall, Anatoli S. Gleiberman, Evguenia Strom, Peter A. Krasnov, David Frescas, Slavoljub Vujcic, Olga V. Leontieva, Marina P. Antoch, Valeria Kogan, Igor E. Koman, Yi Zhu, Tamara Tchkonia, James L. Kirkland, Olga B. Chernova, Andrei V. Gudkov
Aging Cell. 2020 Oct; 19(10): e13219. Published online 2020 Aug 28. doi: 10.1111/acel.13219
PMCID:
PMC7576241
AbstractArticlePDF–3.3M
10.
CRIg plays an essential role in intravascular clearance of bloodborne parasites by interacting with complement
Gongguan Liu, Yong Fu, Mohammed Yosri, Yanli Chen, Peng Sun, Jinjun Xu, Mingshun Zhang, Donglei Sun, Ashley B. Strickland, Zachary B. Mackey, Meiqing Shi
Proc Natl Acad Sci U S A. 2019 Nov 26; 116(48): 24214–24220. Published online 2019 Nov 13. doi: 10.1073/pnas.1913443116
PMCID:
PMC6883839
AbstractArticlePDF–1.2M
11.
Fungal dissemination is limited by liver macrophage filtration of the blood
Donglei Sun, Peng Sun, Hongmei Li, Mingshun Zhang, Gongguan Liu, Ashley B. Strickland, Yanli Chen, Yong Fu, Juan Xu, Mohammed Yosri, Yuchen Nan, Hong Zhou, Xiquan Zhang, Meiqing Shi
Nat Commun. 2019; 10: 4566. Published online 2019 Oct 8. doi: 10.1038/s41467-019-12381-5
PMCID:
PMC6783440
AbstractArticlePDF–3.1M
12.
VSIG4 mediates transcriptional inhibition of Nlrp3 and Il-1β in macrophages
Xiaoyong Huang, Zeqing Feng, Yuanzhong Jiang, Jialin Li, Qun Xiang, Sheng Guo, Chengying Yang, Lei Fei, Guoning Guo, Lixin Zheng, Yuzhang Wu, Yongwen Chen
Sci Adv. 2019 Jan; 5(1): eaau7426. Published online 2019 Jan 9. doi: 10.1126/sciadv.aau7426
PMCID:
PMC6326752
AbstractArticlePDF–8.8M
13.
Inhibition of Macrophage Complement Receptor CRIg by TRIM72 Polarizes Innate Immunity of the Lung
Nagaraja Nagre, Xiaofei Cong, César Terrazas, Ian Pepper, John M. Schreiber, Hongyun Fu, Joshua M. Sill, John W. Christman, Abhay R. Satoskar, Xiaoli Zhao
Am J Respir Cell Mol Biol. 2018 Jun; 58(6): 756–766. doi: 10.1165/rcmb.2017-0236OC
PMCID:
PMC6002657
AbstractArticlePDF–1.7M
14.
CRIg, a tissue-resident macrophage specific immune checkpoint molecule, promotes immunological tolerance in NOD mice, via a dual role in effector and regulatory T cells
Xiaomei Yuan, Bi-Huei Yang, Yi Dong, Asami Yamamura, Wenxian Fu
eLife. 2017; 6: e29540. Published online 2017 Nov 24. doi: 10.7554/eLife.29540
PMCID:
PMC5728720
AbstractArticlePDF–2.5M
15.
VSIG4 inhibits proinflammatory macrophage activation by reprogramming mitochondrial pyruvate metabolism
Jialin Li, Bo Diao, Sheng Guo, Xiaoyong Huang, Chengying Yang, Zeqing Feng, Weiming Yan, Qin Ning, Lixin Zheng, Yongwen Chen, Yuzhang Wu
Nat Commun. 2017; 8: 1322. Published online 2017 Nov 6. doi: 10.1038/s41467-017-01327-4
PMCID:
PMC5673889
AbstractArticlePDF–3.5M
16.
Extracellular stimulation of VSIG4/complement receptor Ig suppresses intracellular bacterial infection by inducing autophagy
Kwang H. Kim, Beom K. Choi, Young H. Kim, Chungyong Han, Ho S. Oh, Don G. Lee, Byoung S. Kwon
Autophagy. 2016; 12(9): 1647–1659. Published online 2016 Jul 20. doi: 10.1080/15548627.2016.1196314
PMCID:
PMC5082771
AbstractArticlePDF–1.3M
17.
The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data
Gautier Koscielny, Gagarine Yaikhom, Vivek Iyer, Terrence F. Meehan, Hugh Morgan, Julian Atienza-Herrero, Andrew Blake, Chao-Kung Chen, Richard Easty, Armida Di Fenza, Tanja Fiegel, Mark Grifiths, Alan Horne, Natasha A. Karp, Natalja Kurbatova, Jeremy C. Mason, Peter Matthews, Darren J. Oakley, Asfand Qazi, Jack Regnart, Ahmad Retha, Luis A. Santos, Duncan J. Sneddon, Jonathan Warren, Henrik Westerberg, Robert J. Wilson, David G. Melvin, Damian Smedley, Steve D. M. Brown, Paul Flicek, William C. Skarnes, Ann-Marie Mallon, Helen Parkinson
Nucleic Acids Res. 2014 Jan 1; 42(Database issue): D802–D809. Published online 2013 Nov 3. doi: 10.1093/nar/gkt977
PMCID:
PMC3964955
AbstractArticlePDF–5.7M
18.
A conditional knockout resource for the genome–wide study of mouse gene function
William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley
Nature. Author manuscript; available in PMC 2013 Feb 14.
Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163
PMCID:
PMC3572410
AbstractArticlePDF–1.1M
19.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
20.
Complement-dependent T-cell lymphopenia caused by thymocyte deletion of the membrane complement regulator Crry
Takashi Miwa, Lin Zhou, Yuko Kimura, David Kim, Avinash Bhandoola, Wen-Chao Song
Blood. 2009 Mar 19; 113(12): 2684–2694. Prepublished online 2009 Jan 9. doi: 10.1182/blood-2008-05-157966
PMCID:
PMC2661856
AbstractArticle

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