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Select item 109685951.

Inhibition of Granule Cell Dispersion and Seizure Development by Astrocyte Elevated Gene-1 in a Mouse Model of Temporal Lobe Epilepsy

Eunju Leem, Sehwan Kim, Chanchal Sharma, Youngpyo Nam, Tae Yeon Kim, Minsang Shin, Seok-Geun Lee, Jaekwang Kim, Sang Ryong Kim

Biomolecules. 2024 Mar; 14(3): 380. Published online 2024 Mar 20. doi: 10.3390/biom14030380

PMCID:: PMC10968595

Abstract Article PDF–8.1M

Select item 98509072.

Astrocyte Elevated Gene-1 Cys75 S-Palmitoylation by ZDHHC6 Regulates Its Biological Activity

Garrison Komaniecki, Maria Del Carmen Camarena, Eric Gelsleichter, Rachel Mendoza, Mark Subler, Jolene J. Windle, Mikhail G. Dozmorov, Zhao Lai, Devanand Sarkar, Hening Lin

Biochemistry. 2023 Jan 17; 62(2): 543–553. Published online 2022 Dec 22. doi: 10.1021/acs.biochem.2c00583

PMCID:: PMC9850907

Abstract Article PDF–5.7M

Select item 88700243.

Dissecting the Balance Between Metabolic and Oncogenic Functions of Astrocyte‐Elevated Gene‐1/Metadherin

Yetirajam Rajesh, Saranya Chidambaranathan Reghupaty, Rachel G. Mendoza, Debashri Manna, Indranil Banerjee, Mark A. Subler, Korri Weldon, Zhao Lai, Shah Giashuddin, Paul B. Fisher, Arun J. Sanyal, Rebecca K. Martin, Mikhail G. Dozmorov, Jolene J. Windle, Devanand Sarkar

Hepatol Commun. 2022 Mar; 6(3): 561–575. Published online 2021 Nov 5. doi: 10.1002/hep4.1834

PMCID:: PMC8870024

Abstract Article PDF–2.1M

Select item 88180884.

Pharmacological Disruption of the MTDH-SND1 Complex Enhances Tumor Antigen Presentation and Synergizes with Anti-PD-1 Therapy in Metastatic Breast Cancer

Minhong Shen, Heath A. Smith, Yong Wei, Yi-Zhou Jiang, Sheng Zhao, Nicole Wang, Michelle Rowicki, Yong Tang, Xiang Hang, Songyang Wu, Liling Wan, Zhi-Ming Shao, Yibin Kang

Nat Cancer. Author manuscript; available in PMC 2022 May 29.

Published in final edited form as: Nat Cancer. 2022 Jan; 3(1): 60–74. Published online 2021 Nov 29. doi: 10.1038/s43018-021-00280-y

PMCID:: PMC8818088

Abstract Article PDF–5.3M

Select item 88180875.

Small Molecule Inhibitors that Disrupt the MTDH-SND1 Complex Suppress Breast Cancer Progression and Metastasis

Minhong Shen, Yong Wei, Hahn Kim, Liling Wan, Yi-Zhou Jiang, Xiang Hang, Michael Raba, Stacy Remiszewski, Michelle Rowicki, Cheng-Guo Wu, Songyang Wu, Lanjing Zhang, Xin Lu, Min Yuan, Heath A. Smith, Aiping Zheng, Joseph Bertino, John F. Jin, Yongna Xing, Zhi-Ming Shao, Yibin Kang

Nat Cancer. Author manuscript; available in PMC 2022 May 29.

Published in final edited form as: Nat Cancer. 2022 Jan; 3(1): 43–59. Published online 2021 Nov 29. doi: 10.1038/s43018-021-00279-5

PMCID:: PMC8818087

Abstract Article PDF–4.6M

Select item 80264916.

Therapeutic Targeting of Metadherin Suppresses Colorectal and Lung Cancer Progression and Metastasis

Minhong Shen, Shanshan Xie, Michelle Rowicki, Sven Michel, Yong Wei, Xiang Hang, Liling Wan, Xin Lu, Min Yuan, John F. Jin, Frank Jaschinski, Tianhua Zhou, Richard Klar, Yibin Kang

Cancer Res. Author manuscript; available in PMC 2021 Aug 15.

Published in final edited form as: Cancer Res. 2021 Feb 15; 81(4): 1014–1025. Published online 2020 Nov 25. doi: 10.1158/0008-5472.CAN-20-1876

PMCID:: PMC8026491

Abstract Article PDF–3.1M

Select item 79387707.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 79270088.

The Scope of Astrocyte Elevated Gene-1/Metadherin (AEG-1/MTDH) in Cancer Clinicopathology: A Review

Maheen Khan, Devanand Sarkar

Genes (Basel) 2021 Feb; 12(2): 308. Published online 2021 Feb 22. doi: 10.3390/genes12020308

PMCID:: PMC7927008

Abstract Article PDF–950K

Select item 74159919.

BioID screening of biotinylation sites using the avidin-like protein Tamavidin 2-REV identifies global interactors of stimulator of interferon genes (STING)

Kou Motani, Hidetaka Kosako

J Biol Chem. 2020 Aug 7; 295(32): 11174–11183. Published online 2020 Jun 17. doi: 10.1074/jbc.RA120.014323

PMCID:: PMC7415991

Abstract Article PDF–2.0M

Select item 736849410.

The sperm associated antigen 6 interactome and its role in spermatogenesis

Yunhao Liu, Ling Zhang, Wei Li, Yuhong Li, Junpin Liu, Shiyang Zhang, Guanglun Pin, Shizhen Song, Pierre F Ray, Christophe Arnoult, Chunghee Cho, Balbina Garcia-Reyes, Uwe Knippschild, Jerome F. Strauss, III, Zhibing Zhang

Reproduction. Author manuscript; available in PMC 2020 Jul 18.

Published in final edited form as: Reproduction. 2019 Aug; 158(2): 181–197. doi: 10.1530/REP-18-0522

PMCID:: PMC7368494

Abstract Article PDF–1.8M

Select item 676064511.

Micheliolide ameliorates renal fibrosis by suppressing the Mtdh/BMP/MAPK pathway

Fenfen Peng, Hongyu Li, Shuting Li, Yuxian Wang, Wenting Liu, Wangqiu Gong, Bohui Yin, Sijia Chen, Ying Zhang, Congwei Luo, Weidong Zhou, Yihua Chen, Peilin Li, Qianyin Huang, Zhaozhong Xu, Haibo Long

Lab Invest. 2019; 99(8): 1092–1106. Published online 2019 Apr 11. doi: 10.1038/s41374-019-0245-6

Correction in:: Lab Invest. 2020; 100(5): 786–787.

PMCID:: PMC6760645

Abstract Article PDF–4.0M

Select item 669277012.

Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics

Joel D. Federspiel, Todd M. Greco, Krystal K. Lum, Ileana M. Cristea

Mol Cell Proteomics. 2019 Aug 9; 18(8 Suppl 1): S92–S113. Published online 2019 Apr 30. doi: 10.1074/mcp.RA118.001253

PMCID:: PMC6692770

Abstract Article PDF–7.7M

Select item 629804013.

Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors

Hyeonwoo Kim, Christiane D. Wrann, Mark Jedrychowski, Sara Vidoni, Yukiko Kitase, Kenichi Nagano, Chenhe Zhou, Joshua Chou, Virginia-Jeni A. Parkman, Scott J. Novick, Timothy S. Strutzenberg, Bruce D. Pascal, Phuong T. Le, Daniel J. Brooks, Alexander M. Roche, Kaitlyn K. Gerber, Laura Mattheis, Wenjing Chen, Hua Tu, Mary L. Bouxsein, Patrick R. Griffin, Roland Baron, Clifford J. Rosen, Lynda F. Bonewald, Bruce M. Spiegelman

Cell. Author manuscript; available in PMC 2019 Dec 13.

Published in final edited form as: Cell. 2018 Dec 13; 175(7): 1756–1768.e17. doi: 10.1016/j.cell.2018.10.025

Correction in:: Cell. 2019 Jul 11; 178(2): 507–508.

PMCID:: PMC6298040

Abstract Article PDF–1.2M

Select item 623994714.

Astrocyte elevated gene-1 (AEG-1) regulates macrophage activation in hepatocellular carcinogenesis

Chadia L. Robertson, Rachel G. Mendoza, Nidhi Jariwala, Mikhail Dozmorov, Nitai D. Mukhopadhyay, Mark A. Subler, Jolene J. Windle, Zhao Lai, Paul B. Fisher, Shobha Ghosh, Devanand Sarkar

Cancer Res. Author manuscript; available in PMC 2019 Nov 15.

Published in final edited form as: Cancer Res. 2018 Nov 15; 78(22): 6436–6446. Published online 2018 Sep 4. doi: 10.1158/0008-5472.CAN-18-0659

PMCID:: PMC6239947

Abstract Article PDF–905K

Select item 551941215.

A Novel Role of Astrocyte Elevated Gene-1 (AEG-1) in Regulating Non-alcoholic Steatohepatitis (NASH)

Jyoti Srivastava, Chadia L. Robertson, Kareem Ebeid, Mikhail Dozmorov, Devaraja Rajasekaran, Rachel Mendoza, Ayesha Siddiq, Maaged A. Akiel, Nidhi Jariwala, Xue-Ning Shen, Jolene J. Windle, Mark A. Subler, Nitai D. Mukhopadhyay, Shah Giashuddin, Shobha Ghosh, Zhao Lai, Yidong Chen, Paul B. Fisher, Aliasger K. Salem, Arun J. Sanyal, Devanand Sarkar

Hepatology. Author manuscript; available in PMC 2018 Aug 1.

Published in final edited form as: Hepatology. 2017 Aug; 66(2): 466–480. Published online 2017 Jun 30. doi: 10.1002/hep.29230

PMCID:: PMC5519412

Abstract Article PDF–1.2M

Select item 526088516.

Metadherin facilitates podocyte apoptosis in diabetic nephropathy

Wen-Ting Liu, Fen-Fen Peng, Hong-Yu Li, Xiao-Wen Chen, Wang-Qiu Gong, Wen-Jing Chen, Yi-Hua Chen, Pei-Lin Li, Shu-Ting Li, Zhao-Zhong Xu, Hai-Bo Long

Cell Death Dis. 2016 Nov; 7(11): e2477. Published online 2016 Nov 24. doi: 10.1038/cddis.2016.335

PMCID:: PMC5260885

Abstract Article PDF–4.1M

Select item 450546817.

Astrocyte Elevated Gene-1 (AEG-1) Contributes to Non-thyroidal Illness Syndrome (NTIS) Associated with Hepatocellular Carcinoma (HCC)

Jyoti Srivastava, Chadia L. Robertson, Rachel Gredler, Ayesha Siddiq, Devaraja Rajasekaran, Maaged A. Akiel, Luni Emdad, Valeria Mas, Nitai D. Mukhopadhyay, Paul B. Fisher, Devanand Sarkar

J Biol Chem. 2015 Jun 19; 290(25): 15549–15558. Published online 2015 May 5. doi: 10.1074/jbc.M115.649707

PMCID:: PMC4505468

Abstract Article PDF–1.3M

Select item 450506518.

Astrocyte Elevated Gene-1 (AEG-1) Regulates Lipid Homeostasis

Chadia L. Robertson, Jyoti Srivastava, Ayesha Siddiq, Rachel Gredler, Luni Emdad, Devaraja Rajasekaran, Maaged Akiel, Xue-Ning Shen, Frank Corwin, Gobalakrishnan Sundaresan, Jamal Zweit, Colleen Croniger, Xiaoli Gao, Shobha Ghosh, Philip B. Hylemon, Mark A. Subler, Jolene J. Windle, Paul B. Fisher, Devanand Sarkar

J Biol Chem. 2015 Jul 17; 290(29): 18227–18236. Published online 2015 Jun 11. doi: 10.1074/jbc.M115.661801

PMCID:: PMC4505065

Abstract Article PDF–1.3M

Select item 442432619.

Genetic Deficiency of Mtdh Gene in Mice Causes Male Infertility via Impaired Spermatogenesis and Alterations in the Expression of Small Non-coding RNAs

Xiangbing Meng, Shujie Yang, Yuping Zhang, Xinjun Wang, Renee X. Goodfellow, Yichen Jia, Kristina W. Thiel, Henry D. Reyes, Baoli Yang, Kimberly K. Leslie

J Biol Chem. 2015 May 8; 290(19): 11853–11864. Published online 2015 Mar 18. doi: 10.1074/jbc.M114.627653

PMCID:: PMC4424326

Abstract Article PDF–4.4M

Select item 430975120.

Astrocyte elevated gene-1 (AEG-1) and c-Myc cooperate to promote hepatocarcinogenesis

Jyoti Srivastava, Ayesha Siddiq, Rachel Gredler, Xue-Ning Shen, Devaraja Rajasekaran, Chadia L. Robertson, Mark A. Subler, Jolene J. Windle, Catherine I. Dumur, Nitai D. Mukhopadhyay, Dawn Garcia, Zhao Lai, Yidong Chen, Uthra Balaji, Paul B. Fisher, Devanand Sarkar

Hepatology. Author manuscript; available in PMC 2016 Mar 1.

Published in final edited form as: Hepatology. 2015 Mar; 61(3): 915–929. Published online 2015 Jan 23. doi: 10.1002/hep.27339

PMCID:: PMC4309751

Abstract Article PDF–1.7M

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