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Items: 1 to 20 of 220

1.
SNP rs11185644 in RXRA gene and SNP rs2235544 in DIO1 gene predict dosage requirements in a cross-sectional sample of hypothyroid patients
Rowan AlEjielat, Anas Khaleel, Yazan S. Batarseh, Luay Abu-Qatouseh, Suzan Al-Wawi, Toleen AlSunna
BMC Endocr Disord. 2023; 23: 167. Published online 2023 Aug 10. doi: 10.1186/s12902-023-01425-z
PMCID:
PMC10413766
AbstractArticlePDF–1022K
2.
lncRNA RMST suppresses the progression of colorectal cancer by competitively binding to miR-27a-3p/RXRα axis and inactivating Wnt signaling pathway: RMST suppresses the progression of colorectal cancer
Shuo Chen, Liechen Ji, Yan Wang, Lin Zhang, Mingyue Xu, Yi’nan Su, Xipeng Zhang
Acta Biochim Biophys Sin (Shanghai) 2023 May; 55(5): 726–735. Published online 2023 May 29. doi: 10.3724/abbs.2023065
PMCID:
PMC10281887
AbstractArticlePDF–2.5M
3.
Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery
Pierre C. Havugimana, Raghuveera Kumar Goel, Sadhna Phanse, Ahmed Youssef, Dzmitry Padhorny, Sergei Kotelnikov, Dima Kozakov, Andrew Emili
Nat Commun. 2022; 13: 4043. Published online 2022 Jul 13. doi: 10.1038/s41467-022-31809-z
PMCID:
PMC9279285
AbstractArticlePDF–2.5M
4.
The role of resveratrol, Sirtuin1 and RXRα as prognostic markers in ovarian cancer
Fangfang Chen, Thomas Kolben, Sarah Meister, Bastian Czogalla, Theresa M. Kolben, Anna Hester, Alexander Burges, Fabian Trillsch, Elisa Schmoeckel, Doris Mayr, Artur Mayerhofer, Sven Mahner, Udo Jeschke, Susanne Beyer
Arch Gynecol Obstet. 2022; 305(6): 1559–1572. Published online 2021 Dec 6. doi: 10.1007/s00404-021-06262-w
PMCID:
PMC9166836
AbstractArticlePDF–1.5M
5.
Cytoplasmic Colocalization of RXRα and PPARγ as an Independent Negative Prognosticator for Breast Cancer Patients
Wanting Shao, Melitta B. Köpke, Theresa Vilsmaier, Alaleh Zati Zehni, Mirjana Kessler, Sophie Sixou, Mariella Schneider, Nina Ditsch, Vincent Cavaillès, Udo Jeschke
Cells. 2022 Apr; 11(7): 1244. Published online 2022 Apr 6. doi: 10.3390/cells11071244
PMCID:
PMC8997589
AbstractArticlePDF–1.5M
6.
Human transcription factor protein interaction networks
Helka Göös, Matias Kinnunen, Kari Salokas, Zenglai Tan, Xiaonan Liu, Leena Yadav, Qin Zhang, Gong-Hong Wei, Markku Varjosalo
Nat Commun. 2022; 13: 766. Published online 2022 Feb 9. doi: 10.1038/s41467-022-28341-5
PMCID:
PMC8828895
AbstractArticlePDF–1.7M
7.
Regulation of Epigenetic Modifications in the Placenta during Preeclampsia: PPARγ Influences H3K4me3 and H3K9ac in Extravillous Trophoblast Cells
Sarah Meister, Laura Hahn, Susanne Beyer, Corinna Paul, Sophie Mitter, Christina Kuhn, Viktoria von Schönfeldt, Stefanie Corradini, Kritika Sudan, Christian Schulz, Theresa Maria Kolben, Sven Mahner, Udo Jeschke, Thomas Kolben
Int J Mol Sci. 2021 Nov; 22(22): 12469. Published online 2021 Nov 18. doi: 10.3390/ijms222212469
PMCID:
PMC8622744
AbstractArticlePDF–4.4M
8.
Association between functional genetic variants in retinoid X receptor-α/γ and the risk of gestational diabetes mellitus in a southern Chinese population
Xiang-yuan Yu, Li-ping Song, Hui-ting Zheng, Shu-dan Wei, Xiao-lan Wen, Bo Huang, Da-bin Liu
Biosci Rep. 2021 Oct 29; 41(10): BSR20211338. Published online 2021 Oct 19. doi: 10.1042/BSR20211338
PMCID:
PMC8529336
AbstractArticlePDF–504K
9.
Integrative oncogene-dependency mapping identifies RIT1 vulnerabilities and synergies in lung cancer
Athea Vichas, Amanda K. Riley, Naomi T. Nkinsi, Shriya Kamlapurkar, Phoebe C. R. Parrish, April Lo, Fujiko Duke, Jennifer Chen, Iris Fung, Jacqueline Watson, Matthew Rees, Austin M. Gabel, James D. Thomas, Robert K. Bradley, John K. Lee, Emily M. Hatch, Marina K. Baine, Natasha Rekhtman, Marc Ladanyi, Federica Piccioni, Alice H. Berger
Nat Commun. 2021; 12: 4789. Published online 2021 Aug 9. doi: 10.1038/s41467-021-24841-y
PMCID:
PMC8352964
AbstractArticlePDF–4.5M
10.
EGR1 and RXRA transcription factors link TGF-β pathway and CCL2 expression in triple negative breast cancer cells
Alisa M. Gorbacheva, Aksinya N. Uvarova, Alina S. Ustiugova, Arindam Bhattacharyya, Kirill V. Korneev, Dmitry V. Kuprash, Nikita A. Mitkin
Sci Rep. 2021; 11: 14120. Published online 2021 Jul 8. doi: 10.1038/s41598-021-93561-6
PMCID:
PMC8266896
AbstractArticlePDF–3.3M
11.
Heterodimer formation with retinoic acid receptor RXRα modulates coactivator recruitment by peroxisome proliferator-activated receptor PPARγ
Whitney Kilu, Daniel Merk, Dieter Steinhilber, Ewgenij Proschak, Jan Heering
J Biol Chem. 2021 Jul; 297(1): 100814. Published online 2021 May 31. doi: 10.1016/j.jbc.2021.100814
PMCID:
PMC8258697
AbstractArticlePDF–2.8M
12.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
13.
Impact of cytosine methylation on DNA binding specificities of human transcription factors
Yimeng Yin, Ekaterina Morgunova, Arttu Jolma, Eevi Kaasinen, Biswajyoti Sahu, Syed Khund-Sayeed, Pratyush K. Das, Teemu Kivioja, Kashyap Dave, Fan Zhong, Kazuhiro R. Nitta, Minna Taipale, Alexander Popov, Paul A. Ginno, Silvia Domcke, Jian Yan, Dirk Schübeler, Charles Vinson, Jussi Taipale
Science. Author manuscript; available in PMC 2021 Mar 30.
Published in final edited form as: Science. 2017 May 5; 356(6337): eaaj2239. doi: 10.1126/science.aaj2239
PMCID:
PMC8009048
AbstractArticlePDF–2.6M
14.
Genome‐wide association study of chemotherapeutic agent‐induced severe neutropenia/leucopenia for patients in Biobank Japan
Siew‐Kee Low, Suyoun Chung, Atsushi Takahashi, Hitoshi Zembutsu, Taisei Mushiroda, Michiaki Kubo, Yusuke Nakamura
Cancer Sci. 2013 Aug; 104(8): 1074–1082. Published online 2013 Jun 10. doi: 10.1111/cas.12186
PMCID:
PMC7657179
AbstractArticlePDF–225K
15.
Molecular determinants of MED1 interaction with the DNA bound VDR–RXR heterodimer
Anna Y Belorusova, Maxime Bourguet, Steve Hessmann, Sandra Chalhoub, Bruno Kieffer, Sarah Cianférani, Natacha Rochel
Nucleic Acids Res. 2020 Nov 4; 48(19): 11199–11213. Published online 2020 Sep 29. doi: 10.1093/nar/gkaa775
PMCID:
PMC7641746
AbstractArticlePDF–3.0M
16.
PML-RARα interaction with TRIB3 impedes PPARγ/RXR function and triggers dyslipidemia in acute promyelocytic leukemia
Ke Li, Feng Wang, Zhao-Na Yang, Bing Cui, Ping-Ping Li, Zhen-Yu Li, Zhuo-Wei Hu, Hong-Hu Zhu
Theranostics. 2020; 10(22): 10326–10340. Published online 2020 Aug 15. doi: 10.7150/thno.45924
PMCID:
PMC7481410
AbstractArticlePDF–3.3M
17.
Characterization of a novel HDAC/RXR/HtrA1 signaling axis as a novel target to overcome cisplatin resistance in human non-small cell lung cancer
Wenjing Wang, Mengyue Zhao, Lijuan Cui, Yong Ren, Jingyuan Zhang, Junli Chen, Lina Jia, Jiayu Zhang, Jingyu Yang, Guoliang Chen, Charles R. Ashby, Jr, Chunfu Wu, Zhe-Sheng Chen, Lihui Wang
Mol Cancer. 2020; 19: 134. Published online 2020 Sep 2. doi: 10.1186/s12943-020-01256-9
PMCID:
PMC7466461
AbstractArticlePDF–3.0M
18.
Bexarotene combined with lapatinib for the treatment of Cushing’s disease: evidence based on drug repositioning and experimental confirmation
Haoying Yu, Shuyue Ren, Jingrong Wang, Tingting Lv, Lan Sun, Guanhua Du
Signal Transduct Target Ther. 2020; 5: 175. Published online 2020 Aug 29. doi: 10.1038/s41392-020-00284-7
PMCID:
PMC7456421
ArticlePDF–1.3M
19.
Agonist binding directs dynamic competition among nuclear receptors for heterodimerization with retinoid X receptor
Lina Fadel, Bálint Rehó, Julianna Volkó, Dóra Bojcsuk, Zsuzsanna Kolostyák, Gergely Nagy, Gabriele Müller, Zoltan Simandi, Éva Hegedüs, Gábor Szabó, Katalin Tóth, Laszlo Nagy, György Vámosi
J Biol Chem. 2020 Jul 17; 295(29): 10045–10061. Published online 2020 Jun 8. doi: 10.1074/jbc.RA119.011614
PMCID:
PMC7380180
AbstractArticlePDF–4.2M
20.
Synthetic lethal and resistance interactions with BET bromodomain inhibitors in triple-negative breast cancer
Shaokun Shu, Hua-Jun Wu, Jennifer Y. Ge, Rhamy Zeid, Isaac S. Harris, Bojana Jovanović, Katherine Murphy, Binbin Wang, Xintao Qiu, Jennifer E. Endress, Jaime Reyes, Klothilda Lim, Alba Font-Tello, Sudeepa Syamala, Tengfei Xiao, Chandra Sekhar Reddy Chilamakuri, Evangelia K. Papachristou, Clive D’Santos, Jayati Anand, Kunihiko Hinohara, Wei Li, Thomas O. McDonald, Adrienne Luoma, Rebecca J. Modiste, Quang-De Nguyen, Brittany Michel, Paloma Cejas, Cigall Kadoch, Jacob D. Jaffe, Kai W. Wucherpfennig, Jun Qi, X. Shirley Liu, Henry Long, Myles Brown, Jason S. Carroll, Joan S. Brugge, James Bradner, Franziska Michor, Kornelia Polyak
Mol Cell. Author manuscript; available in PMC 2021 Jun 18.
Published in final edited form as: Mol Cell. 2020 Jun 18; 78(6): 1096–1113.e8. Published online 2020 May 15. doi: 10.1016/j.molcel.2020.04.027
PMCID:
PMC7306005
AbstractArticlePDF–3.2M

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