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Select item 99318991.

IL-17A expression by both T cells and non-T cells contribute to HSV-IL-2-induced CNS demyelination

Satoshi Hirose, Shaohui Wang, Ujjaldeep Jaggi, Harry H. Matundan, Mihoko Kato, Xue-Ying Song, Sara J. Molesworth-Kenyon, Robert N. Lausch, Homayon Ghiasi

Front Immunol. 2023; 14: 1102486. Published online 2023 Feb 2. doi: 10.3389/fimmu.2023.1102486

PMCID:: PMC9931899

Article PDF–4.9M

Select item 98132072.

IL-17A promotes Helicobacter pylori-induced gastric carcinogenesis via interactions with IL-17RC

Jee Hyun Kang, Suyoung Park, Jinhyung Rho, Eun-Ju Hong, Young-Eun Cho, Young-Suk Won, Hyo-Jung Kwon

Gastric Cancer. 2023; 26(1): 82–94. Published online 2022 Sep 20. doi: 10.1007/s10120-022-01342-5

PMCID:: PMC9813207

Article PDF–2.5M

Select item 97532313.

Interleukin-17 governs hypoxic adaptation of injured epithelium

Piotr Konieczny, Yue Xing, Ikjot Sidhu, Ipsita Subudhi, Kody P. Mansfield, Brandon Hsieh, Douglas E. Biancur, Samantha B. Larsen, Michael Cammer, Dongqing Li, Ning Xu Landén, Cynthia Loomis, Adriana Heguy, Anastasia N. Tikhonova, Aristotelis Tsirigos, Shruti Naik

Science. Author manuscript; available in PMC 2022 Dec 15.

Published in final edited form as: Science. 2022 Jul 8; 377(6602): eabg9302. Published online 2022 Jul 8. doi: 10.1126/science.abg9302

PMCID:: PMC9753231

Article PDF–3.9M

Select item 80179224.

IL17A critically shapes the transcriptional program of fibroblasts in pancreatic cancer and switches on their protumorigenic functions

Gianluca Mucciolo, Claudia Curcio, Cecilia Roux, Wanda Y. Li, Michela Capello, Roberta Curto, Roberto Chiarle, Daniele Giordano, Maria Antonietta Satolli, Rita Lawlor, Aldo Scarpa, Pavol Lukac, Dmitry Stakheev, Paolo Provero, Luca Vannucci, Tak W. Mak, Francesco Novelli, Paola Cappello

Proc Natl Acad Sci U S A. 2021 Feb 9; 118(6): e2020395118. Published online 2021 Feb 1. doi: 10.1073/pnas.2020395118

PMCID:: PMC8017922

Article PDF–1.8M

Select item 74152935.

Role of T_H17 Responses in Increasing Herpetic Keratitis in the Eyes of Mice Infected with HSV-1

Satoshi Hirose, Ujjaldeep Jaggi, Shaohui Wang, Kati Tormanen, Yoshiko Nagaoka, Makoto Katsumata, Homayon Ghiasi

Invest Ophthalmol Vis Sci. 2020 Jun; 61(6): 20. Published online 2020 Jun 9. doi: 10.1167/iovs.61.6.20

PMCID:: PMC7415293

Article PDF–1.9M

Select item 70554846.

γδT cells and adipocyte IL-17RC control fat innervation and thermogenesis

Bo Hu, Chengcheng Jin, Xing Zeng, Jon M. Resch, Mark P. Jedrychowski, Zongfang Yang, Bhavna N. Desai, Alexander S. Banks, Bradford B. Lowell, Diane Mathis, Bruce M. Spiegelman

Nature. Author manuscript; available in PMC 2020 Aug 19.

Published in final edited form as: Nature. 2020 Feb; 578(7796): 610–614. Published online 2020 Feb 19. doi: 10.1038/s41586-020-2028-z

PMCID:: PMC7055484

Article PDF–4.1M

Select item 64433337.

Potential role of the IL17RC gene in the thoracic ossification of the posterior longitudinal ligament

Peng Wang, Xiaoguang Liu, Chao Kong, Xiao Liu, Ze Teng, Yunlong Ma, Lei Yong, Chen Liang, Guanping He, Shibao Lu

Int J Mol Med. 2019 May; 43(5): 2005–2014. Published online 2019 Mar 12. doi: 10.3892/ijmm.2019.4130

PMCID:: PMC6443333

Article PDF–1.3M

Select item 63798098.

IL-17A Recruits Rab35 to IL-17R to Mediate PKCα-Dependent Stress Fiber Formation and Airway Smooth Muscle Contractility

Katarzyna Bulek, Xing Chen, Vandy Parron, Aparna Sundaram, Tomasz Herjan, Suidong Ouyang, Caini Liu, Alana Majors, Jarod Zepp, Ji Gao, Ashok Dongre, Malgorzata Bodaszewska-Lubas, Arnaud Echard, Mark Aronica, Julie Carman, Stavros Garantziotis, Dean Sheppard, Xiaoxia Li

J Immunol. 2019 Mar 1; 202(5): 1540–1548. Published online 2019 Jan 25. doi: 10.4049/jimmunol.1801025

PMCID:: PMC6379809

Article PDF–2.0M

Select item 63145259.

IL-17R–EGFR axis links wound healing to tumorigenesis in Lrig1⁺ stem cells

Xing Chen, Gang Cai, Caini Liu, Junjie Zhao, Chunfang Gu, Ling Wu, Thomas A. Hamilton, Cun-jin Zhang, Jennifer Ko, Liang Zhu, Jun Qin, Allison Vidimos, Shlomo Koyfman, Brian R. Gastman, Kim B. Jensen, Xiaoxia Li

J Exp Med. 2019 Jan 7; 216(1): 195–214. doi: 10.1084/jem.20171849

PMCID:: PMC6314525

Article PDF–6.9M

Select item 577149310.

IL-17A-induced Plet1 expression contributes to tissue repair and colon tumorigenesis

Jarod A. Zepp, Junjie Zhao, Caini Liu, Katazyna Bulek, Ling Wu, Xing Chen, Yujun Hao, Zhenghe Wang, Xinxin Wang, Wenjun Ouyang, Matthew F. Kalady, Julie Carman, Wen-Pin Yang, Jun Zhu, Clare Blackburn, Yina H. Huang, Thomas Hamilton, Bing Su, Xiaoxia Li

J Immunol. Author manuscript; available in PMC 2018 Dec 1.

Published in final edited form as: J Immunol. 2017 Dec 1; 199(11): 3849–3857. Published online 2017 Oct 25. doi: 10.4049/jimmunol.1601540

PMCID:: PMC5771493

Article PDF–953K

Select item 552213511.

IL-17RC is critically required to maintain baseline A20 production to repress JNK isoform-dependent tumor-specific proliferation

Chi Yan, Yang Lei, Tong-Jun Lin, David W. Hoskin, Averil Ma, Jun Wang

Oncotarget. 2017 Jun 27; 8(26): 43153–43168. Published online 2017 May 11. doi: 10.18632/oncotarget.17820

PMCID:: PMC5522135

Article PDF–8.7M

Select item 552099412.

The flavonoid cyanidin blocks binding of the cytokine interleukin-17A to the IL-17RA subunit to alleviate inflammation in vivo

Caini Liu, Liang Zhu, Koichi Fukuda, Suidong Ouyang, Xing Chen, Chenhui Wang, Cun-jin Zhang, Bradley Martin, Chunfang Gu, Luke Qin, Suguna Rachakonda, Mark Aronica, Jun Qin, Xiaoxia Li

Sci Signal. Author manuscript; available in PMC 2017 Jul 21.

Published in final edited form as: Sci Signal. 2017 Feb 21; 10(467): eaaf8823. Published online 2017 Feb 21. doi: 10.1126/scisignal.aaf8823

PMCID:: PMC5520994

Article PDF–1017K

Select item 541107913.

Pneumocystis driven inducible bronchus associated lymphoid tissue formation requires Th2 and Th17 immunity

Taylor Eddens, Waleed Elsegeiny, Maria de la Luz Garcia-Hernadez, Patricia Castillo, Giraldina Trevejo-Nunez, Katelin Serody, Brian T. Campfield, Shabaana A. Khader, Kong Chen, Javier Rangel-Moreno, Jay K. Kolls

Cell Rep. Author manuscript; available in PMC 2017 May 1.

Published in final edited form as: Cell Rep. 2017 Mar 28; 18(13): 3078–3090. doi: 10.1016/j.celrep.2017.03.016

PMCID:: PMC5411079

Article PDF–2.5M

Select item 535395714.

Increased IL-17RA and IL-17RC in End-Stage COPD and the Contribution to Mast Cell Secretion of FGF-2 and VEGF

Abraham B. Roos, Michiko Mori, Harpreet K. Gura, Axel Lorentz, Leif Bjermer, Hans Jürgen Hoffmann, Jonas S. Erjefält, Martin R. Stampfli

Respir Res. 2017; 18: 48. Published online 2017 Mar 15. doi: 10.1186/s12931-017-0534-9

PMCID:: PMC5353957

Article PDF–721K

Select item 514940615.

IL-17 receptor signaling in the lung epithelium is required for mucosal chemokine gradients and pulmonary host defense against K. pneumoniae

Kong Chen, Taylor Eddens, Giraldina Trevejo-Nunez, Emily E. Way, Waleed Elsegeiny, David M. Ricks, Abhishek V. Garg, Carla J. Erb, Meihua Bo, Ting Wang, Wei Chen, Janet S. Lee, Sarah L. Gaffen, Jay K. Kolls

Cell Host Microbe. Author manuscript; available in PMC 2017 Nov 9.

Published in final edited form as: Cell Host Microbe. 2016 Nov 9; 20(5): 596–605. Published online 2016 Oct 27. doi: 10.1016/j.chom.2016.10.003

PMCID:: PMC5149406

Article PDF–1.6M

Select item 479475016.

Intestinal interleukin-17 receptor signaling mediates reciprocal control of the gut microbiota and autoimmune inflammation

Pawan Kumar, Leticia Monin, Patricia Castillo, Waleed Elsegeiny, William Horne, Taylor Eddens, Amit Vikram, Misty Good, Alexi A. Schoenborn, Kyle Bibby, Ronald C. Montelaro, Dennis W. Metzger, Ajay S. Gulati, Jay K. Kolls

Immunity. Author manuscript; available in PMC 2017 Mar 15.

Published in final edited form as: Immunity. 2016 Mar 15; 44(3): 659–671. doi: 10.1016/j.immuni.2016.02.007

PMCID:: PMC4794750

Article PDF–1.4M

Select item 438849017.

Signaling through IL-17C/IL-17RE Is Dispensable for Immunity to Systemic, Oral and Cutaneous Candidiasis

Heather R. Conti, Natasha Whibley, Bianca M. Coleman, Abhishek V. Garg, Jillian R. Jaycox, Sarah L. Gaffen

PLoS One. 2015; 10(4): e0122807. Published online 2015 Apr 7. doi: 10.1371/journal.pone.0122807

PMCID:: PMC4388490

Article PDF–613K

Select item 406329918.

Interleukin-17 promotes development of castration-resistant prostate cancer potentially through creating an immunotolerant and pro-angiogenic tumor microenvironment

Qiuyang Zhang, Sen Liu, Qingsong Zhang, Zhenggang Xiong, Alun R. Wang, Leann Myers, Jonathan Melamed, Wendell W. Tang, Zongbing You

Prostate. Author manuscript; available in PMC 2015 Jun 1.

Published in final edited form as: Prostate. 2014 Jun; 74(8): 869–879. Published online 2014 Apr 1. doi: 10.1002/pros.22805

PMCID:: PMC4063299

Article PDF–1.7M

Select item 397289219.

Autocrine IL-17A–IL-17RC neutrophil activation in fungal infections is regulated by IL-6, IL-23, ROR?t and Dectin-2

Patricia R. Taylor, Sanhita Roy, Sixto M. Leal, Jr., Yan Sun, Scott J. Howell, Brian A. Cobb, Xiaoxia Li, Eric Pearlman

Nat Immunol. Author manuscript; available in PMC 2014 Aug 1.

Published in final edited form as: Nat Immunol. 2014 Feb; 15(2): 143–151. Published online 2013 Dec 22. doi: 10.1038/ni.2797

Correction in:: volume 16 on page 214

PMCID:: PMC3972892

Article PDF–1.2M

Select item 366515820.

Interleulin-17 Promotes Formation and Growth of Prostate Adenocarcinoma in Mouse Models

Qiuyang Zhang, Sen Liu, Dongxia Ge, Qingsong Zhang, Yun Xue, Zhenggang Xiong, Asim B. Abdel–Mageed, Leann Myers, Steven M. Hill, Brian G. Rowan, Oliver Sartor, Jonathan Melamed, Zhenbang Chen, Zongbing You

Cancer Res. Author manuscript; available in PMC 2013 May 28.

Published in final edited form as: Cancer Res. 2012 May 15; 72(10): 2589–2599. Published online 2012 Mar 28. doi: 10.1158/0008-5472.CAN-11-3795