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Select item 92897091.

TRIM27 cooperates with STK38L to inhibit ULK1‐mediated autophagy and promote tumorigenesis

Yi Yang, Yifu Zhu, Shuai Zhou, Peipei Tang, Ran Xu, Yuwei Zhang, Dongping Wei, Jian Wen, Rick F Thorne, Xu Dong Zhang, Jun‐Lin Guan, Lianxin Liu, Mian Wu, Song Chen

EMBO J. 2022 Jul; 41(14): e109777. Published online 2022 Jun 7. doi: 10.15252/embj.2021109777

PMCID:: PMC9289709

Article PDF–2.3M

Select item 90021352.

Expression of a RhoA-Specific Guanine Nucleotide Exchange Factor, p190RhoGEF, in Mouse Macrophages Negatively Affects M1 Polarization and Inflammatory Responses

So-Yeon Choi, Yu Ri Ahn, Eun-Bi Lee, Mi Jin Yu, Jong Ran Lee

Front Immunol. 2022; 13: 782475. Published online 2022 Mar 29. doi: 10.3389/fimmu.2022.782475

PMCID:: PMC9002135

Article PDF–3.8M

Select item 83132393.

Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development

Francesco Bedogni, Robert F. Hevner

Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034

PMCID:: PMC8313239

Article PDF–1.6M

Select item 79387704.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Article PDF–2.0M

Select item 78651855.

ZFP57 dictates allelic expression switch of target imprinted genes

Weijun Jiang, Jiajia Shi, Jingjie Zhao, Qiu Wang, Dan Cong, Fenghua Chen, Yu Zhang, Yuhan Liu, Junzheng Zhao, Qian Chen, Linhao Gu, Wenjia Zhou, Chenhang Wang, Zhaoyuan Fang, Shuhui Geng, Wei Xie, Luo-Nan Chen, Yang Yang, Yun Bai, Haodong Lin, Xiajun Li

Proc Natl Acad Sci U S A. 2021 Feb 2; 118(5): e2005377118. Published online 2021 Jan 26. doi: 10.1073/pnas.2005377118

PMCID:: PMC7865185

Article PDF–1.8M

Select item 67936316.

Distinct Roles for Ras-Guanine Nucleotide-Releasing Factor 1 (Ras-GRF1) and Ras-GRF2 in the Induction of Long-Term Potentiation and Long-Term Depression

Shaomin Li, Xuejun Tian, Dean M. Hartley, Larry A. Feig

J Neurosci. 2006 Feb 8; 26(6): 1721–1729. doi: 10.1523/JNEUROSCI.3990-05.2006

PMCID:: PMC6793631

Article PDF–421K

Select item 66879057.

The Inhibition of RasGRF2, But Not RasGRF1, Alters Cocaine Reward in Mice

Rick E. Bernardi, Anastasia Olevska, Ilaria Morella, Stefania Fasano, Eugenio Santos, Riccardo Brambilla, Rainer Spanagel

J Neurosci. 2019 Aug 7; 39(32): 6325–6338. doi: 10.1523/JNEUROSCI.1120-18.2019

PMCID:: PMC6687905

Article PDF–1.8M

Select item 66752608.

ERK-Dependent Modulation of Cerebellar Synaptic Plasticity after Chronic Δ9-Tetrahydrocannabinol Exposure

Raffaella Tonini, Sonia Ciardo, Milica Cerovic, Tiziana Rubino, Daniela Parolaro, Michele Mazzanti, Renata Zippel

J Neurosci. 2006 May 24; 26(21): 5810–5818. doi: 10.1523/JNEUROSCI.5469-05.2006

PMCID:: PMC6675260

Article PDF–367K

Select item 62362499.

Spatial learning and long‐term memory impairments in RasGrf1 KO, Pttg1 KO, and double KO mice

Lara Manyes, Sarah Holst, Manuel Lozano, Eugenio Santos, Alberto Fernandez‐Medarde

Brain Behav. 2018 Nov; 8(11): e01089. Published online 2018 Sep 26. doi: 10.1002/brb3.1089

PMCID:: PMC6236249

Article PDF–770K

Select item 621302810.

Deletion of RasGRF1 Attenuated Interstitial Fibrosis in Streptozotocin-Induced Diabetic Cardiomyopathy in Mice through Affecting Inflammation and Oxidative Stress

Tzu-Hsien Tsai, Cheng-Jei Lin, Sarah Chua, Sheng-Ying Chung, Shyh-Ming Chen, Chien-Ho Lee, Chi-Ling Hang

Int J Mol Sci. 2018 Oct; 19(10): 3094. Published online 2018 Oct 10. doi: 10.3390/ijms19103094

PMCID:: PMC6213028

Article PDF–5.9M

Select item 619412711.

Genetic enhancement of Ras-ERK pathway does not aggravate L-DOPA-induced dyskinesia in mice but prevents the decrease induced by lovastatin

Irene Ruiz-DeDiego, Stefania Fasano, Oscar Solís, José-Rubén Garcia-Montes, José Brea, María I. Loza, Riccardo Brambilla, Rosario Moratalla

Sci Rep. 2018; 8: 15381. Published online 2018 Oct 18. doi: 10.1038/s41598-018-33713-3

PMCID:: PMC6194127

Article PDF–3.8M

Select item 554226712.

Association of RASgrf1 methylation with epileptic seizures

Xiaoni Chen, Xi Peng, Liang Wang, Xinwei Fu, Ji Xiu Zhou, Binglin Zhu, Jing Luo, Xuefeng Wang, Zheng Xiao

Oncotarget. 2017 Jul 11; 8(28): 46286–46297. Published online 2017 May 19. doi: 10.18632/oncotarget.18000

PMCID:: PMC5542267

Article PDF–9.1M

Select item 497241813.

Gene expression analysis of the embryonic subplate

Franziska M. Oeschger, Wei-Zhi Wang, Sheena Lee, Fernando García-Moreno, André M. Goffinet, Mariona Arbones, Sonia Rakic, Zoltán Molnár

Cereb Cortex. Author manuscript; available in PMC 2016 Aug 3.

Published in final edited form as: Cereb Cortex. 2012 Jun; 22(6): 1343–1359. Published online 2011 Aug 22. doi: 10.1093/cercor/bhr197

PMCID:: PMC4972418

Article PDF–7.1M

Select item 458024514.

Very low density lipoprotein receptor regulates dendritic spine formation in a RasGRF1/CaMKII dependent manner

Amanda Marie DiBattista, Sonya B. Dumanis, Jung Min Song, Guojun Bu, Edwin Weeber, G. William Rebeck, Hyang-Sook Hoe

Biochim Biophys Acta. Author manuscript; available in PMC 2016 May 1.

Published in final edited form as: Biochim Biophys Acta. 2015 May; 1853(5): 904–917. Published online 2015 Jan 31. doi: 10.1016/j.bbamcr.2015.01.015

PMCID:: PMC4580245

Article PDF–2.5M

Select item 456099115.

RasGRF1 Regulates the Hypothalamic-Pituitary-Adrenal Axis Specifically in Early-Adolescent Female Mice

Belkis Gizem Uzturk, Shan-xue Jin, Beverly Rubin, Christopher Bartolome, Larry A. Feig

J Endocrinol. Author manuscript; available in PMC 2016 Aug 1.

Published in final edited form as: J Endocrinol. 2015 Oct; 227(1): 227–238. Published online 2015 Aug 5. doi: 10.1530/JOE-15-0304

PMCID:: PMC4560991

Article PDF–482K

Select item 447952616.

Differential involvement of Ras-GRF1 and Ras-GRF2 in L-DOPA-induced dyskinesia

Simone Bido, Nicola Solari, Marzia Indrigo, Angela D’Antoni, Riccardo Brambilla, Michele Morari, Stefania Fasano

Ann Clin Transl Neurol. 2015 Jun; 2(6): 662–678. Published online 2015 Apr 24. doi: 10.1002/acn3.202

PMCID:: PMC4479526

Article PDF–1.8M

Select item 431955917.

A high resolution spatiotemporal atlas of gene expression of the developing mouse brain

Carol L. Thompson, Lydia Ng, Vilas Menon, Salvador Martinez, Chang-Kyu Lee, Katie Glattfelder, Susan M. Sunkin, Alex Henry, Christopher Lau, Chinh Dang, Raquel Garcia-Lopez, Almudena Martinez-Ferre, Ana Pombero, John L.R. Rubenstein, Wayne B. Wakeman, John Hohmann, Nick Dee, Andrew J. Sodt, Rob Young, Kimberly Smith, Thuc-Nghi Nguyen, Jolene Kidney, Leonard Kuan, Andreas Jeromin, Ajamete Kaykas, Jeremy Miller, Damon Page, Geri Orta, Amy Bernard, Zackery Riley, Simon Smith, Paul Wohnoutka, Mike Hawrylycz, Luis Puelles, Allan R. Jones

Neuron. Author manuscript; available in PMC 2015 Jul 16.

Published in final edited form as: Neuron. 2014 Jul 16; 83(2): 309–323. Published online 2014 Jun 19. doi: 10.1016/j.neuron.2014.05.033

PMCID:: PMC4319559

Article PDF–3.0M

Select item 430145018.

Transcriptional profiling reveals functional links between RasGrf1 and Pttg1 in pancreatic beta cells

Lara Manyes, Monica Arribas, Carmela Gomez, Nuria Calzada, Alberto Fernandez-Medarde, Eugenio Santos

BMC Genomics. 2014; 15: 1019. Published online 2014 Nov 25. doi: 10.1186/1471-2164-15-1019

PMCID:: PMC4301450

Article PDF–2.3M

Select item 420395319.

CARD9 mediates Dectin-1–induced ERK activation by linking Ras-GRF1 to H-Ras for antifungal immunity

Xin-Ming Jia, Bing Tang, Le-Le Zhu, Yan-Hui Liu, Xue-Qiang Zhao, Sara Gorjestani, Yen-Michael S. Hsu, Long Yang, Jian-Hong Guan, Guo-Tong Xu, Xin Lin

J Exp Med. 2014 Oct 20; 211(11): 2307–2321. doi: 10.1084/jem.20132349

PMCID:: PMC4203953

Article PDF–2.4M

Select item 411514820.

A genome-wide association study for myopia and refractive error identifies a susceptibility locus at 15q25

Pirro G Hysi, Terri L Young, David A Mackey, Toby Andrew, Alberto Fernández-Medarde, Abbas M Solouki, Alex W Hewitt, Stuart Macgregor, Johannes R Vingerling, Yi-Ju Li, M Kamran Ikram, Lee Yiu Fai, Pak C Sham, Lara Manyes, Angel Porteros, Margarida C Lopes, Francis Carbonaro, Samantha J Fahy, Nicholas G Martin, Cornelia M van Duijn, Timothy D Spector, Jugnoo S Rahi, Eugenio Santos, Caroline C W Klaver, Christopher J Hammond

Nat Genet. Author manuscript; available in PMC 2014 Jul 30.

Published in final edited form as: Nat Genet. 2010 Oct; 42(10): 902–905. Published online 2010 Sep 12. doi: 10.1038/ng.664

PMCID:: PMC4115148

Article PDF–288K

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